PT72596B - Process for the preparation of new 2(1h)-pyridone derivatives having pharmaceutical effect - Google Patents
Process for the preparation of new 2(1h)-pyridone derivatives having pharmaceutical effectInfo
- Publication number
- PT72596B PT72596B PT72596A PT7259681A PT72596B PT 72596 B PT72596 B PT 72596B PT 72596 A PT72596 A PT 72596A PT 7259681 A PT7259681 A PT 7259681A PT 72596 B PT72596 B PT 72596B
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- new
- pharmaceutical effect
- pyridone derivatives
- pyridone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH166880 | 1980-03-03 | ||
| CH166980 | 1980-03-03 | ||
| CH571780 | 1980-07-25 | ||
| CH794780 | 1980-10-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT72596A PT72596A (en) | 1981-04-01 |
| PT72596B true PT72596B (en) | 1982-07-13 |
Family
ID=27428258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT72596A PT72596B (en) | 1980-03-03 | 1981-03-02 | Process for the preparation of new 2(1h)-pyridone derivatives having pharmaceutical effect |
Country Status (16)
| Country | Link |
|---|---|
| CA (1) | CA1183533A (en) |
| CH (1) | CH652395A5 (en) |
| DE (1) | DE3106460A1 (en) |
| DK (1) | DK94481A (en) |
| ES (1) | ES8301469A1 (en) |
| FI (1) | FI810558L (en) |
| FR (1) | FR2477148A1 (en) |
| GB (1) | GB2070606B (en) |
| IL (1) | IL62246A (en) |
| IT (1) | IT1142458B (en) |
| NL (1) | NL8100964A (en) |
| NZ (1) | NZ196385A (en) |
| PT (1) | PT72596B (en) |
| SE (1) | SE8101336L (en) |
| WO (1) | WO1981002575A1 (en) |
| YU (1) | YU51581A (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL65278A0 (en) * | 1981-03-30 | 1982-05-31 | Sterling Drug Inc | 3-amino-5-(substituted)-2(1h)-pyridinones and corresponding 3-cyano compounds,their preparation and pharmaceutical compositions containing them |
| US4465686A (en) * | 1981-09-08 | 1984-08-14 | Sterling Drug Inc. | 5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation |
| US4515797A (en) * | 1981-09-08 | 1985-05-07 | Sterling Drug Inc. | 3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof |
| US4432979A (en) * | 1981-10-26 | 1984-02-21 | William H. Rorer, Inc. | Pyridone compounds |
| US4593028A (en) * | 1981-10-26 | 1986-06-03 | William H. Rorer, Inc. | 5-hetero aryl-substituted-2-pyridones useful as cardiotonic agents for treatment of congestive heart failure |
| US4514400A (en) * | 1981-10-26 | 1985-04-30 | William H. Rorer, Inc. | Cardiotonic 5-heteroaryl-pyridone |
| US4539321A (en) * | 1981-10-26 | 1985-09-03 | William H. Rorer, Inc. | 5-Diaza-aryl-3-substituted pyridone compounds |
| AT384021B (en) * | 1982-05-18 | 1987-09-25 | Sandoz Ag | Process for the preparation of novel 2(1H)-pyridinone derivatives and their salts |
| FR2527206B1 (en) * | 1982-05-18 | 1986-12-05 | Sandoz Sa | NOVEL 2 (1H) -PYRIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS |
| FR2529891A1 (en) * | 1982-07-12 | 1984-01-13 | Nativelle Sa Ets | PYRIDYL-3 ALCOXY-5 PYRAZOLE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC APPLICATION |
| IL69407A (en) * | 1982-08-23 | 1987-10-20 | Warner Lambert Co | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
| US4503061A (en) * | 1983-07-22 | 1985-03-05 | Warner-Lambert Company | Substituted phenyl-pyridinones as cardiotonic agents |
| IT8367883A0 (en) * | 1982-08-23 | 1983-08-22 | Rorer Int Overseas | CARDIOTONIC COMPOUNDS OF SUBSTITUTED BICYCLIC 2 PYRIDONE 5 HETEROARYL AND RELATED PHARMACEUTICAL COMPOSITIONS |
| US4517192A (en) * | 1983-01-31 | 1985-05-14 | Sterling Drug Inc. | 6-Alkyl-5-[4-(alkylsulfinyl or alkylsulfonyl)phenyl]-2(1H)-pyridinones and their use as cardiatonics |
| ES521644A0 (en) * | 1983-04-20 | 1985-10-16 | Quimicos Y Farmaceuticos Abel | A NEW PROCEDURE FOR THE PREPARATION OF 5-AZINYL-1,2-DIHYDROAZIN-2-ONAS. |
| US4568751A (en) * | 1983-04-29 | 1986-02-04 | Merrell Dow Pharmaceuticals Inc. | 5-Acyl-2-(1H)-pyridinones |
| DE3406329A1 (en) * | 1984-02-22 | 1985-08-22 | Merck Patent Gmbh, 6100 Darmstadt | PYRIDONE |
| DE3685840D1 (en) | 1985-04-30 | 1992-08-06 | Dresden Arzneimittel | 3-CYAN-PYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACEUTICAL USE. |
| US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
| US4785005A (en) * | 1986-06-25 | 1988-11-15 | Rorer Pharmaceutical Corporation | 6-(6-alkylpyridone)-carbostyril compounds and their cardiotonic uses |
| GB8809481D0 (en) * | 1988-04-21 | 1988-05-25 | Smith Kline French Lab | Chemical compounds |
| US5254571A (en) * | 1988-04-21 | 1993-10-19 | Smith Kline & French Laboratories Ltd. | Chemical compounds |
| GB8923131D0 (en) * | 1989-10-13 | 1989-11-29 | Smith Kline French Lab | Chemical compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3355278A (en) * | 1961-03-13 | 1967-11-28 | Hooker Chemical Corp | Herbicidal composition and method |
| NL6816241A (en) * | 1967-12-01 | 1969-06-03 | ||
| FR2050940A5 (en) * | 1969-06-30 | 1971-04-02 | Rhone Poulenc Sa | |
| US3666765A (en) * | 1969-10-27 | 1972-05-30 | Union Carbide Corp | Synthesis of 2-pyridones and derivatives thereof |
| US3721676A (en) * | 1969-11-12 | 1973-03-20 | Merck & Co Inc | Certain 3-amino-2(1h)pyridones |
| BE758759A (en) * | 1969-11-12 | 1971-05-10 | Merck & Co Inc | ANTI-INFLAMMATORY PYRIDONES |
| US4038396A (en) * | 1975-02-24 | 1977-07-26 | Merck & Co., Inc. | Anti-inflammatory oxazole[4,5-b]pyridines |
| US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
-
1981
- 1981-02-21 DE DE19813106460 patent/DE3106460A1/en not_active Withdrawn
- 1981-02-24 FI FI810558A patent/FI810558L/en not_active Application Discontinuation
- 1981-02-27 FR FR8104152A patent/FR2477148A1/en active Granted
- 1981-02-27 CH CH7325/81A patent/CH652395A5/en not_active IP Right Cessation
- 1981-02-27 GB GB8106335A patent/GB2070606B/en not_active Expired
- 1981-02-27 NL NL8100964A patent/NL8100964A/en not_active Application Discontinuation
- 1981-02-27 WO PCT/CH1981/000023 patent/WO1981002575A1/en unknown
- 1981-03-02 SE SE8101336A patent/SE8101336L/en not_active Application Discontinuation
- 1981-03-02 CA CA000372050A patent/CA1183533A/en not_active Expired
- 1981-03-02 DK DK94481A patent/DK94481A/en not_active Application Discontinuation
- 1981-03-02 IT IT47920/81A patent/IT1142458B/en active
- 1981-03-02 IL IL62246A patent/IL62246A/en unknown
- 1981-03-02 NZ NZ196385A patent/NZ196385A/en unknown
- 1981-03-02 PT PT72596A patent/PT72596B/en unknown
- 1981-03-02 YU YU00515/81A patent/YU51581A/en unknown
- 1981-03-02 ES ES499971A patent/ES8301469A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| YU51581A (en) | 1983-12-31 |
| FR2477148B1 (en) | 1983-09-02 |
| FR2477148A1 (en) | 1981-09-04 |
| IT8147920A0 (en) | 1981-03-02 |
| SE8101336L (en) | 1981-09-04 |
| WO1981002575A1 (en) | 1981-09-17 |
| DE3106460A1 (en) | 1982-01-28 |
| NZ196385A (en) | 1983-12-16 |
| NL8100964A (en) | 1981-10-01 |
| IL62246A (en) | 1984-09-30 |
| GB2070606A (en) | 1981-09-09 |
| CH652395A5 (en) | 1985-11-15 |
| IT1142458B (en) | 1986-10-08 |
| ES499971A0 (en) | 1982-12-01 |
| CA1183533A (en) | 1985-03-05 |
| IL62246A0 (en) | 1981-05-20 |
| GB2070606B (en) | 1984-02-29 |
| DK94481A (en) | 1981-09-04 |
| PT72596A (en) | 1981-04-01 |
| FI810558L (en) | 1981-09-04 |
| ES8301469A1 (en) | 1982-12-01 |
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