IT8367883A0 - CARDIOTONIC COMPOUNDS OF SUBSTITUTED BICYCLIC 2 PYRIDONE 5 HETEROARYL AND RELATED PHARMACEUTICAL COMPOSITIONS - Google Patents
CARDIOTONIC COMPOUNDS OF SUBSTITUTED BICYCLIC 2 PYRIDONE 5 HETEROARYL AND RELATED PHARMACEUTICAL COMPOSITIONSInfo
- Publication number
- IT8367883A0 IT8367883A0 IT8367883A IT6788383A IT8367883A0 IT 8367883 A0 IT8367883 A0 IT 8367883A0 IT 8367883 A IT8367883 A IT 8367883A IT 6788383 A IT6788383 A IT 6788383A IT 8367883 A0 IT8367883 A0 IT 8367883A0
- Authority
- IT
- Italy
- Prior art keywords
- pyridone
- heteroaryl
- pharmaceutical compositions
- substituted bicyclic
- related pharmaceutical
- Prior art date
Links
- 230000003177 cardiotonic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- UBQKCCHYAOITMY-UHFFFAOYSA-N pyridin-2-ol Chemical compound OC1=CC=CC=N1 UBQKCCHYAOITMY-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41064682A | 1982-08-23 | 1982-08-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
IT8367883A0 true IT8367883A0 (en) | 1983-08-22 |
Family
ID=23625622
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8367883A IT8367883A0 (en) | 1982-08-23 | 1983-08-22 | CARDIOTONIC COMPOUNDS OF SUBSTITUTED BICYCLIC 2 PYRIDONE 5 HETEROARYL AND RELATED PHARMACEUTICAL COMPOSITIONS |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0118528A4 (en) |
JP (1) | JPS59501716A (en) |
AU (1) | AU2038683A (en) |
IT (1) | IT8367883A0 (en) |
WO (1) | WO1984000756A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2568251B1 (en) * | 1984-07-26 | 1988-05-27 | Mitsui Toatsu Chemicals | NEW ISOQUINOLEIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS |
JPS625963A (en) * | 1985-07-02 | 1987-01-12 | Mitsui Toatsu Chem Inc | Isoquinoline derivative |
US4785005A (en) * | 1986-06-25 | 1988-11-15 | Rorer Pharmaceutical Corporation | 6-(6-alkylpyridone)-carbostyril compounds and their cardiotonic uses |
US4859672A (en) * | 1986-10-29 | 1989-08-22 | Rorer Pharmaceutical Corporation | Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone |
US5002944A (en) * | 1986-10-29 | 1991-03-26 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having cardiotonic activity |
ES2072015T3 (en) * | 1990-08-21 | 1995-07-01 | Upjohn Co | DERIVATIVES OF THE BISPHOSPHONIC ACID AS AN ANTI-ARTHRITIC AGENT. |
US5141931A (en) * | 1991-01-03 | 1992-08-25 | Sterling Winthrop Inc. | 5-Quinolinylpyridinones, cardiotonic compositions and methods |
CZ403592A3 (en) * | 1992-02-20 | 1993-12-15 | Hoechst Ag | Arylcarbonylaminoalkyldihydrooxopyridines, process of their preparation and their use |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2242787C2 (en) * | 1972-08-31 | 1982-01-21 | Bayer Ag, 5090 Leverkusen | 4-Phenyl-6-amino-3,4-dihydropyridon- (2) -3,5-dicarboxylic acid diethyl ester derivatives, a process for their preparation and pharmaceuticals containing them |
US3981882A (en) * | 1972-08-31 | 1976-09-21 | Bayer Aktiengesellschaft | Process for preparing 4-aryl of hetero-6-amino-3,4-dihydropyrid-2-one-3,5-dicarboxylic acid ester |
US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
US4271168A (en) * | 1979-12-26 | 1981-06-02 | Sterling Drug Inc. | Selected 3-acylamino-5-[4(or 3)-pyridinyl]-2(1H)-pyridinones |
DE3106460A1 (en) * | 1980-03-03 | 1982-01-28 | Sandoz-Patent-GmbH, 7850 Lörrach | 2 (1H) -PYRIDINONE DERIVATIVES, THEIR PRODUCTION AND THE PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME |
-
1983
- 1983-08-22 IT IT8367883A patent/IT8367883A0/en unknown
- 1983-08-23 JP JP58502958A patent/JPS59501716A/en active Pending
- 1983-08-23 EP EP19830902935 patent/EP0118528A4/en not_active Withdrawn
- 1983-08-23 AU AU20386/83A patent/AU2038683A/en not_active Abandoned
- 1983-08-23 WO PCT/US1983/001285 patent/WO1984000756A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0118528A4 (en) | 1985-09-09 |
WO1984000756A1 (en) | 1984-03-01 |
EP0118528A1 (en) | 1984-09-19 |
AU2038683A (en) | 1984-03-07 |
JPS59501716A (en) | 1984-10-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT86974A (en) | PROCESS FOR THE PREPARATION OF IMIDAZOL COMPOUNDS AND OF BIOCIDDAL COMPOSITIONS CONTAINING THE SAME | |
IT1143056B (en) | PROCEDURE FOR THE PRODUCTION OF TYPE II INTERFERON AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | |
NO831873L (en) | PROCEDURE FOR THE PREPARATION OF NEW ALKAN AND ALKENDER DERIVATIVES | |
PT71999A (en) | Novel quinoline derivatives pharmaceutical compositions containing such compounds and method for the preparation of these compounds | |
IL58579A0 (en) | Nitrogen heterocyclic compounds their preparation and pharmaceutical compositions containing them | |
NO164171C (en) | ANALOGY PROCEDURE FOR THE PREPARATION OF BICYCLIC HETEROCYCYLYCLE-CONTAINING N- (BICYCLEIC HETEROCYCYLYL) -4-PIPERIDINAMINES | |
NO844433L (en) | PROCEDURE FOR PROCESSING OF COMPOSITION MATERIALS | |
FI834057A0 (en) | ANORDINATION FOR THE EXTENSION OF MATERIALS | |
PT75827B (en) | Process for the preparation of heterocyclic derivatives of phenlthiadiazinone oxadiazinone and triadiazinone and pharmaceutical compositions therewith | |
SE8300912D0 (en) | COMPOSITIONS FOR TREATMENT OF GLAUCOM | |
PT87470A (en) | PROCESS FOR THE PREPARATION OF NOVEL SUBSTITUTED BENZAMIDES AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | |
IT1194748B (en) | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF OSTEOPATHIES | |
PT87699A (en) | PROCESS FOR THE PREPARATION OF TRICYCLIC PYRIDONE DERIVATIVES AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | |
IT8367883A0 (en) | CARDIOTONIC COMPOUNDS OF SUBSTITUTED BICYCLIC 2 PYRIDONE 5 HETEROARYL AND RELATED PHARMACEUTICAL COMPOSITIONS | |
IT8049163A0 (en) | SUBSTITUTED HETEROCYCLIC PHENOXYAMINE PROCEDURE FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM | |
IL49835A (en) | Preparation of 2,4-dioxo-1,2,3,4tetrahydro-s-triazino-(1,2-a)benzimidazoles, certain such novel compounds and fungicidal compositions containing them | |
SE8300913D0 (en) | COMPOSITIONS FOR TREATMENT OF GLAUCOM | |
IT1162463B (en) | PROCEDURE FOR THE PREPARATION OF CEPHALOSPORINS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PRODUCT OBTAINED | |
PT84184A (en) | PROCESS FOR THE PREPARATION OF 8 ALPHA-ACYLAMINOERGOLINES AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
IT8149370A0 (en) | ANTIHYPERTENSIVE QUINOLONE COMPOUNDS VI PHARMACEUTICAL COMPOSITIONS THEY CONTAIN AND PROCEDURE FOR PRODUCING THEM | |
IL57476A0 (en) | Compounds of the muramy-peptide type and pharmaceutical compositions containing them | |
PT72619B (en) | Novel quinoline derivatives pharmaceutical compositions con- taining such compounds and methods for the preparation of these compounds | |
PT87441A (en) | PROCESS FOR THE PREPARATION OF CARDIOTONIC TRICYCLIC IMIDAZOLONES AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | |
FI792303A (en) | PHARMACEUTICAL COMPOSITION FOR THE ADMINISTRATION OF KEFALOSPORIN | |
IT8148776A0 (en) | HETEROCYCLIC COMPOUNDS THEIR PHARMACEUTICAL PREPARATION AND COMPOSITION CONTAINING THESE COMPOUNDS |