IT1142458B - 2 (1H) -PYRIDONE DERIVATIVES THEIR PREPARATION AND THERAPEUTIC APPLICATION - Google Patents
2 (1H) -PYRIDONE DERIVATIVES THEIR PREPARATION AND THERAPEUTIC APPLICATIONInfo
- Publication number
- IT1142458B IT1142458B IT47920/81A IT4792081A IT1142458B IT 1142458 B IT1142458 B IT 1142458B IT 47920/81 A IT47920/81 A IT 47920/81A IT 4792081 A IT4792081 A IT 4792081A IT 1142458 B IT1142458 B IT 1142458B
- Authority
- IT
- Italy
- Prior art keywords
- preparation
- therapeutic application
- pyridone derivatives
- pyridone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH166880 | 1980-03-03 | ||
| CH166980 | 1980-03-03 | ||
| CH571780 | 1980-07-25 | ||
| CH794780 | 1980-10-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8147920A0 IT8147920A0 (en) | 1981-03-02 |
| IT1142458B true IT1142458B (en) | 1986-10-08 |
Family
ID=27428258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT47920/81A IT1142458B (en) | 1980-03-03 | 1981-03-02 | 2 (1H) -PYRIDONE DERIVATIVES THEIR PREPARATION AND THERAPEUTIC APPLICATION |
Country Status (16)
| Country | Link |
|---|---|
| CA (1) | CA1183533A (en) |
| CH (1) | CH652395A5 (en) |
| DE (1) | DE3106460A1 (en) |
| DK (1) | DK94481A (en) |
| ES (1) | ES8301469A1 (en) |
| FI (1) | FI810558L (en) |
| FR (1) | FR2477148A1 (en) |
| GB (1) | GB2070606B (en) |
| IL (1) | IL62246A (en) |
| IT (1) | IT1142458B (en) |
| NL (1) | NL8100964A (en) |
| NZ (1) | NZ196385A (en) |
| PT (1) | PT72596B (en) |
| SE (1) | SE8101336L (en) |
| WO (1) | WO1981002575A1 (en) |
| YU (1) | YU51581A (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL65278A0 (en) * | 1981-03-30 | 1982-05-31 | Sterling Drug Inc | 3-amino-5-(substituted)-2(1h)-pyridinones and corresponding 3-cyano compounds,their preparation and pharmaceutical compositions containing them |
| US4515797A (en) * | 1981-09-08 | 1985-05-07 | Sterling Drug Inc. | 3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof |
| US4465686A (en) * | 1981-09-08 | 1984-08-14 | Sterling Drug Inc. | 5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation |
| US4593028A (en) * | 1981-10-26 | 1986-06-03 | William H. Rorer, Inc. | 5-hetero aryl-substituted-2-pyridones useful as cardiotonic agents for treatment of congestive heart failure |
| US4432979A (en) * | 1981-10-26 | 1984-02-21 | William H. Rorer, Inc. | Pyridone compounds |
| US4514400A (en) * | 1981-10-26 | 1985-04-30 | William H. Rorer, Inc. | Cardiotonic 5-heteroaryl-pyridone |
| US4539321A (en) * | 1981-10-26 | 1985-09-03 | William H. Rorer, Inc. | 5-Diaza-aryl-3-substituted pyridone compounds |
| FR2527206B1 (en) * | 1982-05-18 | 1986-12-05 | Sandoz Sa | NOVEL 2 (1H) -PYRIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS |
| AT384021B (en) * | 1982-05-18 | 1987-09-25 | Sandoz Ag | Process for the preparation of novel 2(1H)-pyridinone derivatives and their salts |
| FR2529891A1 (en) * | 1982-07-12 | 1984-01-13 | Nativelle Sa Ets | PYRIDYL-3 ALCOXY-5 PYRAZOLE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC APPLICATION |
| US4503061A (en) * | 1983-07-22 | 1985-03-05 | Warner-Lambert Company | Substituted phenyl-pyridinones as cardiotonic agents |
| IL69407A (en) * | 1982-08-23 | 1987-10-20 | Warner Lambert Co | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
| IT8367883A0 (en) * | 1982-08-23 | 1983-08-22 | Rorer Int Overseas | CARDIOTONIC COMPOUNDS OF SUBSTITUTED BICYCLIC 2 PYRIDONE 5 HETEROARYL AND RELATED PHARMACEUTICAL COMPOSITIONS |
| US4517192A (en) * | 1983-01-31 | 1985-05-14 | Sterling Drug Inc. | 6-Alkyl-5-[4-(alkylsulfinyl or alkylsulfonyl)phenyl]-2(1H)-pyridinones and their use as cardiatonics |
| ES8600746A1 (en) * | 1983-04-20 | 1985-10-16 | Quimicos Y Farmaceuticos Abel | Process for the preparation of 5-pyridyl-pyridine-2(1H)-ones. |
| US4568751A (en) * | 1983-04-29 | 1986-02-04 | Merrell Dow Pharmaceuticals Inc. | 5-Acyl-2-(1H)-pyridinones |
| DE3406329A1 (en) * | 1984-02-22 | 1985-08-22 | Merck Patent Gmbh, 6100 Darmstadt | PYRIDONE |
| EP0200024B1 (en) | 1985-04-30 | 1992-07-01 | ARZNEIMITTELWERK DRESDEN GmbH | 3-cyano-pyridines, process for their preparation and their pharmaceutical use |
| US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
| US4785005A (en) * | 1986-06-25 | 1988-11-15 | Rorer Pharmaceutical Corporation | 6-(6-alkylpyridone)-carbostyril compounds and their cardiotonic uses |
| GB8809481D0 (en) * | 1988-04-21 | 1988-05-25 | Smith Kline French Lab | Chemical compounds |
| US5254571A (en) * | 1988-04-21 | 1993-10-19 | Smith Kline & French Laboratories Ltd. | Chemical compounds |
| GB8923131D0 (en) * | 1989-10-13 | 1989-11-29 | Smith Kline French Lab | Chemical compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3355278A (en) * | 1961-03-13 | 1967-11-28 | Hooker Chemical Corp | Herbicidal composition and method |
| NL6816241A (en) * | 1967-12-01 | 1969-06-03 | ||
| FR2050940A5 (en) * | 1969-06-30 | 1971-04-02 | Rhone Poulenc Sa | |
| US3666765A (en) * | 1969-10-27 | 1972-05-30 | Union Carbide Corp | Synthesis of 2-pyridones and derivatives thereof |
| BE758759A (en) * | 1969-11-12 | 1971-05-10 | Merck & Co Inc | ANTI-INFLAMMATORY PYRIDONES |
| US3721676A (en) * | 1969-11-12 | 1973-03-20 | Merck & Co Inc | Certain 3-amino-2(1h)pyridones |
| US4038396A (en) * | 1975-02-24 | 1977-07-26 | Merck & Co., Inc. | Anti-inflammatory oxazole[4,5-b]pyridines |
| US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
-
1981
- 1981-02-21 DE DE19813106460 patent/DE3106460A1/en not_active Withdrawn
- 1981-02-24 FI FI810558A patent/FI810558L/en not_active Application Discontinuation
- 1981-02-27 GB GB8106335A patent/GB2070606B/en not_active Expired
- 1981-02-27 NL NL8100964A patent/NL8100964A/en not_active Application Discontinuation
- 1981-02-27 WO PCT/CH1981/000023 patent/WO1981002575A1/en unknown
- 1981-02-27 FR FR8104152A patent/FR2477148A1/en active Granted
- 1981-02-27 CH CH7325/81A patent/CH652395A5/en not_active IP Right Cessation
- 1981-03-02 YU YU00515/81A patent/YU51581A/en unknown
- 1981-03-02 IT IT47920/81A patent/IT1142458B/en active
- 1981-03-02 ES ES499971A patent/ES8301469A1/en not_active Expired
- 1981-03-02 NZ NZ196385A patent/NZ196385A/en unknown
- 1981-03-02 PT PT72596A patent/PT72596B/en unknown
- 1981-03-02 CA CA000372050A patent/CA1183533A/en not_active Expired
- 1981-03-02 SE SE8101336A patent/SE8101336L/en not_active Application Discontinuation
- 1981-03-02 DK DK94481A patent/DK94481A/en not_active Application Discontinuation
- 1981-03-02 IL IL62246A patent/IL62246A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| YU51581A (en) | 1983-12-31 |
| NL8100964A (en) | 1981-10-01 |
| CA1183533A (en) | 1985-03-05 |
| FI810558L (en) | 1981-09-04 |
| NZ196385A (en) | 1983-12-16 |
| ES499971A0 (en) | 1982-12-01 |
| CH652395A5 (en) | 1985-11-15 |
| ES8301469A1 (en) | 1982-12-01 |
| PT72596A (en) | 1981-04-01 |
| DK94481A (en) | 1981-09-04 |
| DE3106460A1 (en) | 1982-01-28 |
| PT72596B (en) | 1982-07-13 |
| IT8147920A0 (en) | 1981-03-02 |
| IL62246A0 (en) | 1981-05-20 |
| WO1981002575A1 (en) | 1981-09-17 |
| FR2477148B1 (en) | 1983-09-02 |
| GB2070606B (en) | 1984-02-29 |
| IL62246A (en) | 1984-09-30 |
| GB2070606A (en) | 1981-09-09 |
| FR2477148A1 (en) | 1981-09-04 |
| SE8101336L (en) | 1981-09-04 |
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