PT72596B - Process for the preparation of new 2(1h)-pyridone derivatives having pharmaceutical effect - Google Patents
Process for the preparation of new 2(1h)-pyridone derivatives having pharmaceutical effectInfo
- Publication number
- PT72596B PT72596B PT72596A PT7259681A PT72596B PT 72596 B PT72596 B PT 72596B PT 72596 A PT72596 A PT 72596A PT 7259681 A PT7259681 A PT 7259681A PT 72596 B PT72596 B PT 72596B
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- new
- pharmaceutical effect
- pyridone derivatives
- pyridone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH166980 | 1980-03-03 | ||
| CH166880 | 1980-03-03 | ||
| CH571780 | 1980-07-25 | ||
| CH794780 | 1980-10-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT72596A PT72596A (en) | 1981-04-01 |
| PT72596B true PT72596B (en) | 1982-07-13 |
Family
ID=27428258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT72596A PT72596B (en) | 1980-03-03 | 1981-03-02 | Process for the preparation of new 2(1h)-pyridone derivatives having pharmaceutical effect |
Country Status (16)
| Country | Link |
|---|---|
| CA (1) | CA1183533A (fr) |
| CH (1) | CH652395A5 (fr) |
| DE (1) | DE3106460A1 (fr) |
| DK (1) | DK94481A (fr) |
| ES (1) | ES499971A0 (fr) |
| FI (1) | FI810558L (fr) |
| FR (1) | FR2477148A1 (fr) |
| GB (1) | GB2070606B (fr) |
| IL (1) | IL62246A (fr) |
| IT (1) | IT1142458B (fr) |
| NL (1) | NL8100964A (fr) |
| NZ (1) | NZ196385A (fr) |
| PT (1) | PT72596B (fr) |
| SE (1) | SE8101336L (fr) |
| WO (1) | WO1981002575A1 (fr) |
| YU (1) | YU51581A (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL65278A0 (en) * | 1981-03-30 | 1982-05-31 | Sterling Drug Inc | 3-amino-5-(substituted)-2(1h)-pyridinones and corresponding 3-cyano compounds,their preparation and pharmaceutical compositions containing them |
| US4515797A (en) * | 1981-09-08 | 1985-05-07 | Sterling Drug Inc. | 3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof |
| US4465686A (en) * | 1981-09-08 | 1984-08-14 | Sterling Drug Inc. | 5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation |
| US4514400A (en) * | 1981-10-26 | 1985-04-30 | William H. Rorer, Inc. | Cardiotonic 5-heteroaryl-pyridone |
| US4593028A (en) * | 1981-10-26 | 1986-06-03 | William H. Rorer, Inc. | 5-hetero aryl-substituted-2-pyridones useful as cardiotonic agents for treatment of congestive heart failure |
| US4539321A (en) * | 1981-10-26 | 1985-09-03 | William H. Rorer, Inc. | 5-Diaza-aryl-3-substituted pyridone compounds |
| US4432979A (en) * | 1981-10-26 | 1984-02-21 | William H. Rorer, Inc. | Pyridone compounds |
| AT384021B (de) * | 1982-05-18 | 1987-09-25 | Sandoz Ag | Verfahren zur herstellung neuer 2(1h)-pyridinon- derivate und ihrer salze |
| FR2527206B1 (fr) * | 1982-05-18 | 1986-12-05 | Sandoz Sa | Nouveaux derives de la 2(1h)-pyridinone, leur preparation et leur utilisation comme medicaments |
| FR2529891A1 (fr) * | 1982-07-12 | 1984-01-13 | Nativelle Sa Ets | Derives du pyridyl-3 alcoxy-5 pyrazole, procede de preparation et application en therapeutique |
| IT8367883A0 (it) * | 1982-08-23 | 1983-08-22 | Rorer Int Overseas | Composti cardiotonici del 2 piridone 5 biciclico eteroaril sostituito e relative composizioni farmaceutiche |
| IL69407A (en) * | 1982-08-23 | 1987-10-20 | Warner Lambert Co | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
| US4503061A (en) * | 1983-07-22 | 1985-03-05 | Warner-Lambert Company | Substituted phenyl-pyridinones as cardiotonic agents |
| US4517192A (en) * | 1983-01-31 | 1985-05-14 | Sterling Drug Inc. | 6-Alkyl-5-[4-(alkylsulfinyl or alkylsulfonyl)phenyl]-2(1H)-pyridinones and their use as cardiatonics |
| ES8600746A1 (es) * | 1983-04-20 | 1985-10-16 | Quimicos Y Farmaceuticos Abel | Un nuevo procedimiento para la preparacion de 5-azinil-1,2-dihidroazin-2-onas. |
| US4568751A (en) * | 1983-04-29 | 1986-02-04 | Merrell Dow Pharmaceuticals Inc. | 5-Acyl-2-(1H)-pyridinones |
| DE3406329A1 (de) * | 1984-02-22 | 1985-08-22 | Merck Patent Gmbh, 6100 Darmstadt | Pyridone |
| ATE77817T1 (de) | 1985-04-30 | 1992-07-15 | Dresden Arzneimittel | 3-cyan-pyridine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung. |
| US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
| US4785005A (en) * | 1986-06-25 | 1988-11-15 | Rorer Pharmaceutical Corporation | 6-(6-alkylpyridone)-carbostyril compounds and their cardiotonic uses |
| US5254571A (en) * | 1988-04-21 | 1993-10-19 | Smith Kline & French Laboratories Ltd. | Chemical compounds |
| GB8809481D0 (en) * | 1988-04-21 | 1988-05-25 | Smith Kline French Lab | Chemical compounds |
| GB8923131D0 (en) * | 1989-10-13 | 1989-11-29 | Smith Kline French Lab | Chemical compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3355278A (en) * | 1961-03-13 | 1967-11-28 | Hooker Chemical Corp | Herbicidal composition and method |
| NL6816241A (fr) * | 1967-12-01 | 1969-06-03 | ||
| FR2050940A5 (fr) * | 1969-06-30 | 1971-04-02 | Rhone Poulenc Sa | |
| US3666765A (en) * | 1969-10-27 | 1972-05-30 | Union Carbide Corp | Synthesis of 2-pyridones and derivatives thereof |
| US3721676A (en) * | 1969-11-12 | 1973-03-20 | Merck & Co Inc | Certain 3-amino-2(1h)pyridones |
| BE758759A (fr) * | 1969-11-12 | 1971-05-10 | Merck & Co Inc | Pyridones anti-inflammatoires |
| US4038396A (en) * | 1975-02-24 | 1977-07-26 | Merck & Co., Inc. | Anti-inflammatory oxazole[4,5-b]pyridines |
| US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
-
1981
- 1981-02-21 DE DE19813106460 patent/DE3106460A1/de not_active Withdrawn
- 1981-02-24 FI FI810558A patent/FI810558L/fi not_active Application Discontinuation
- 1981-02-27 WO PCT/CH1981/000023 patent/WO1981002575A1/fr unknown
- 1981-02-27 NL NL8100964A patent/NL8100964A/nl not_active Application Discontinuation
- 1981-02-27 GB GB8106335A patent/GB2070606B/en not_active Expired
- 1981-02-27 FR FR8104152A patent/FR2477148A1/fr active Granted
- 1981-02-27 CH CH7325/81A patent/CH652395A5/de not_active IP Right Cessation
- 1981-03-02 YU YU00515/81A patent/YU51581A/xx unknown
- 1981-03-02 DK DK94481A patent/DK94481A/da not_active Application Discontinuation
- 1981-03-02 SE SE8101336A patent/SE8101336L/xx not_active Application Discontinuation
- 1981-03-02 NZ NZ196385A patent/NZ196385A/xx unknown
- 1981-03-02 PT PT72596A patent/PT72596B/pt unknown
- 1981-03-02 CA CA000372050A patent/CA1183533A/fr not_active Expired
- 1981-03-02 ES ES499971A patent/ES499971A0/es active Granted
- 1981-03-02 IL IL62246A patent/IL62246A/xx unknown
- 1981-03-02 IT IT47920/81A patent/IT1142458B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| WO1981002575A1 (fr) | 1981-09-17 |
| CA1183533A (fr) | 1985-03-05 |
| FI810558L (fi) | 1981-09-04 |
| ES8301469A1 (es) | 1982-12-01 |
| SE8101336L (sv) | 1981-09-04 |
| DK94481A (da) | 1981-09-04 |
| YU51581A (en) | 1983-12-31 |
| IT8147920A0 (it) | 1981-03-02 |
| IT1142458B (it) | 1986-10-08 |
| CH652395A5 (de) | 1985-11-15 |
| DE3106460A1 (de) | 1982-01-28 |
| IL62246A0 (en) | 1981-05-20 |
| IL62246A (en) | 1984-09-30 |
| FR2477148A1 (fr) | 1981-09-04 |
| ES499971A0 (es) | 1982-12-01 |
| FR2477148B1 (fr) | 1983-09-02 |
| GB2070606A (en) | 1981-09-09 |
| NL8100964A (nl) | 1981-10-01 |
| PT72596A (en) | 1981-04-01 |
| GB2070606B (en) | 1984-02-29 |
| NZ196385A (en) | 1983-12-16 |
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