DE2912414A1 - 2-(4-aethyl-1-piperazinyl)-4-phenylchinolin und dessen salze mit saeuren, verfahren zu ihrer herstellung und ihre verwendung als antidepressive wirkstoffe - Google Patents

2-(4-aethyl-1-piperazinyl)-4-phenylchinolin und dessen salze mit saeuren, verfahren zu ihrer herstellung und ihre verwendung als antidepressive wirkstoffe

Info

Publication number
DE2912414A1
DE2912414A1 DE19792912414 DE2912414A DE2912414A1 DE 2912414 A1 DE2912414 A1 DE 2912414A1 DE 19792912414 DE19792912414 DE 19792912414 DE 2912414 A DE2912414 A DE 2912414A DE 2912414 A1 DE2912414 A1 DE 2912414A1
Authority
DE
Germany
Prior art keywords
compound
piperazinyl
ethyl
phenylquinoline
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19792912414
Other languages
German (de)
English (en)
Other versions
DE2912414C2 (https=
Inventor
Kiyoshi Furukawa
Tadahiko Karasawa
Yasutaka Nagai
Hitoshi Uno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd filed Critical Dainippon Pharmaceutical Co Ltd
Publication of DE2912414A1 publication Critical patent/DE2912414A1/de
Application granted granted Critical
Publication of DE2912414C2 publication Critical patent/DE2912414C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
DE19792912414 1978-03-29 1979-03-29 2-(4-aethyl-1-piperazinyl)-4-phenylchinolin und dessen salze mit saeuren, verfahren zu ihrer herstellung und ihre verwendung als antidepressive wirkstoffe Granted DE2912414A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3702978A JPS54128588A (en) 1978-03-29 1978-03-29 Antidepressive drugs consisting mainly of 2-(1-piperazinyl)- 4-phenylquinoline

Publications (2)

Publication Number Publication Date
DE2912414A1 true DE2912414A1 (de) 1979-10-04
DE2912414C2 DE2912414C2 (https=) 1988-03-17

Family

ID=12486204

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19792912414 Granted DE2912414A1 (de) 1978-03-29 1979-03-29 2-(4-aethyl-1-piperazinyl)-4-phenylchinolin und dessen salze mit saeuren, verfahren zu ihrer herstellung und ihre verwendung als antidepressive wirkstoffe

Country Status (6)

Country Link
US (1) US4237135A (https=)
JP (1) JPS54128588A (https=)
DE (1) DE2912414A1 (https=)
FR (1) FR2421173A1 (https=)
GB (1) GB2017698B (https=)
IT (1) IT1121456B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79603B (https=) * 1982-07-24 1984-10-31 Pfizer
JPS59222418A (ja) * 1983-05-31 1984-12-14 Dainippon Pharmaceut Co Ltd 抗潰瘍剤
US4677107A (en) * 1983-05-31 1987-06-30 Dainippon Pharmaceutical Co., Ltd. Anti-peptic ulcer agent
WO1986003198A1 (fr) * 1984-11-27 1986-06-05 Dainippon Pharmaceutical Co., Ltd. Derives de 2-(1-piperazinyle)-4-substitue phenylquinoline, procede de preparation et composition medicinale les contenant
FR2637591B1 (fr) * 1988-10-11 1992-10-23 Synthelabo Derives de quinoleinone, leur preparation et leur application en therapeutique
DK0385237T3 (da) * 1989-03-03 1994-07-25 Dainippon Pharmaceutical Co 2-(1-Piperazinyl)-4-phenylcycloalkanopyridinderivater, fremgangsmåde til fremstilling deraf og farmaceutisk præparat indeholdende dem
CA2144669A1 (en) * 1994-03-29 1995-09-30 Kozo Akasaka Biphenyl derivatives

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3542785A (en) * 1967-05-15 1970-11-24 Ciba Geigy Corp 2-hydroxy-4-aryl-quinolines
US3668207A (en) * 1970-01-22 1972-06-06 Ciba Geigy Corp 2-amino-4-aryl-quinolines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3576809A (en) * 1968-05-06 1971-04-27 Miles Lab 2-substituted derivatives of 6-methoxyquinoline
US3737540A (en) * 1972-02-14 1973-06-05 Miles Lab Composition for suppressing the tremor of parkinson's syndrome

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3542785A (en) * 1967-05-15 1970-11-24 Ciba Geigy Corp 2-hydroxy-4-aryl-quinolines
US3668207A (en) * 1970-01-22 1972-06-06 Ciba Geigy Corp 2-amino-4-aryl-quinolines

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
C.A.74, 125470n (1971) *
C.A.77, 126452g (1972) *
Helv.Chim.Acta 60, 1644 (1977) *
J.Am.Chem.Soc. 70, 2402 (1948) *

Also Published As

Publication number Publication date
JPS6344749B2 (https=) 1988-09-06
FR2421173B1 (https=) 1983-01-28
GB2017698A (en) 1979-10-10
FR2421173A1 (fr) 1979-10-26
JPS54128588A (en) 1979-10-05
US4237135A (en) 1980-12-02
GB2017698B (en) 1982-08-04
IT7967658A0 (it) 1979-03-29
DE2912414C2 (https=) 1988-03-17
IT1121456B (it) 1986-04-02

Similar Documents

Publication Publication Date Title
DE2915318A1 (de) Cycloalkyltriazole, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2846945A1 (de) Pharmazeutische praeparate
EP0000220B1 (de) Dihydrouracile, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE3306006A1 (de) Pyrrolessigsaeureamide mit antiinflammatorischer aktivitaet, verfahren zu deren herstellung und arzneimittel, die dieselben enthalten
DE2363052A1 (de) 3-phenyl-3-aminoalkyl-2,6-dioxo-tetraund -hexahydropyridine, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen zubereitungen
DE60204044T2 (de) Piperazin derivate mit sst1 antagonistischer wirkung
DE3855520T2 (de) Methode zur Verbesserung des Schlafes
DE3334757A1 (de) Piperazinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate
DD281596A5 (de) Verfahren zur hersteung antiarrhytmischer mittel
DE2434951A1 (de) 3-substituierte diphenylhydantoine
DE2912414A1 (de) 2-(4-aethyl-1-piperazinyl)-4-phenylchinolin und dessen salze mit saeuren, verfahren zu ihrer herstellung und ihre verwendung als antidepressive wirkstoffe
DE3115552A1 (de) 4,1-benzoxazepine und diese verbindungen enthaltende arzneimittel
DE69311566T2 (de) Heterocyclische amine als calmodulin antagonisten
AT396362B (de) 5,5-dimethyl-3-phenylvinyl-1-aminoalkoxy-iminocyclohex-2-enderivate
DE3216843C2 (de) 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE69331234T2 (de) Neue nicotinsäureester
DE1695111B1 (de) Indolderivate
DE69115954T2 (de) Kondensierte 7-gliedrige zyklische Verbindungen und diese enthaltende antipsychotische Zubereitung
DE3112984A1 (de) 2-(3-(4-(3-chlor-4-fluorphenyl)-1-piperazinyl) propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-on dessen pharmazeutische anwendung und herstellung
CH620685A5 (https=)
CH649289A5 (de) 2-pyridyl- und 2-pyrimidylaminobenzoesaeuren.
DE1926359A1 (de) oxylkansaeuren
DE2435381C2 (de) 8-(2-Dimethylaminoäthyl)-3-oxo-4-phenyl-1-thia-4,8-diazaspiro[4.5]decan und seine Salze mit Säuren, Verfahren zu ihrer Herstellung und deren Verwendung in Arzneipräparaten
DE69821019T2 (de) 3-carboalkoxy-2,3-dihydro-1h-phenothiazin-4(10h)-one derivate
DE1470110A1 (de) Verfahren zur Herstellung von Dioxodibenzothiadiazepinderivaten

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: C07D215/46

D2 Grant after examination
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: VOSSIUS, V., DIPL.-CHEM. DR.RER.NAT. TAUCHNER, P., DIPL.-CHEM. DR.RER.NAT. HEUNEMANN, D., DIPL.-PHYS. DR.RER.NAT., PAT.-ANWAELTE, 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee
8328 Change in the person/name/address of the agent

Free format text: TAUCHNER, P., DIPL.-CHEM. DR.RER.NAT. HEUNEMANN, D., DIPL.-PHYS. DR.RER.NAT., PAT.-ANWAELTE, 8000 MUENCHEN