JPS54128588A - Antidepressive drugs consisting mainly of 2-(1-piperazinyl)- 4-phenylquinoline - Google Patents

Antidepressive drugs consisting mainly of 2-(1-piperazinyl)- 4-phenylquinoline

Info

Publication number
JPS54128588A
JPS54128588A JP3702978A JP3702978A JPS54128588A JP S54128588 A JPS54128588 A JP S54128588A JP 3702978 A JP3702978 A JP 3702978A JP 3702978 A JP3702978 A JP 3702978A JP S54128588 A JPS54128588 A JP S54128588A
Authority
JP
Japan
Prior art keywords
compound
formula
piperazinyl
phenylquinoline
antidepressive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3702978A
Other languages
English (en)
Other versions
JPS6344749B2 (ja
Inventor
Jun Uno
Yasutaka Nagai
Tadahiko Karasawa
Kiyoshi Furukawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dainippon Pharmaceutical Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd filed Critical Dainippon Pharmaceutical Co Ltd
Priority to JP3702978A priority Critical patent/JPS54128588A/ja
Priority to US06/022,779 priority patent/US4237135A/en
Priority to GB7910802A priority patent/GB2017698B/en
Priority to FR7907932A priority patent/FR2421173A1/fr
Priority to IT67658/79A priority patent/IT1121456B/it
Priority to DE19792912414 priority patent/DE2912414A1/de
Publication of JPS54128588A publication Critical patent/JPS54128588A/ja
Publication of JPS6344749B2 publication Critical patent/JPS6344749B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
JP3702978A 1978-03-29 1978-03-29 Antidepressive drugs consisting mainly of 2-(1-piperazinyl)- 4-phenylquinoline Granted JPS54128588A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP3702978A JPS54128588A (en) 1978-03-29 1978-03-29 Antidepressive drugs consisting mainly of 2-(1-piperazinyl)- 4-phenylquinoline
US06/022,779 US4237135A (en) 1978-03-29 1979-03-22 2-(4-Ethyl-1-piperazinyl)-4-phenylquinoline, process for preparation thereof, and composition thereof
GB7910802A GB2017698B (en) 1978-03-29 1979-03-28 2-(4-ethyl-1-piperazinyl)-4-phenylquinoline and pharmaceutical compositions thereof
FR7907932A FR2421173A1 (fr) 1978-03-29 1979-03-29 2-(4-ethylpiperazino)-4-phenylquinoleine et ses sels, utiles notamment comme antidepresseurs, et leur procede de preparation
IT67658/79A IT1121456B (it) 1978-03-29 1979-03-29 2 4 etil i pipera inil 4 fenilchinoline procedimento per la loro preparazione e composizioni farmaceutiche contenenti tali composti
DE19792912414 DE2912414A1 (de) 1978-03-29 1979-03-29 2-(4-aethyl-1-piperazinyl)-4-phenylchinolin und dessen salze mit saeuren, verfahren zu ihrer herstellung und ihre verwendung als antidepressive wirkstoffe

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3702978A JPS54128588A (en) 1978-03-29 1978-03-29 Antidepressive drugs consisting mainly of 2-(1-piperazinyl)- 4-phenylquinoline

Publications (2)

Publication Number Publication Date
JPS54128588A true JPS54128588A (en) 1979-10-05
JPS6344749B2 JPS6344749B2 (ja) 1988-09-06

Family

ID=12486204

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3702978A Granted JPS54128588A (en) 1978-03-29 1978-03-29 Antidepressive drugs consisting mainly of 2-(1-piperazinyl)- 4-phenylquinoline

Country Status (6)

Country Link
US (1) US4237135A (ja)
JP (1) JPS54128588A (ja)
DE (1) DE2912414A1 (ja)
FR (1) FR2421173A1 (ja)
GB (1) GB2017698B (ja)
IT (1) IT1121456B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003198A1 (en) * 1984-11-27 1986-06-05 Dainippon Pharmaceutical Co., Ltd. 2-(1-piperazinyl)-4-substituted phenylquinoline derivatives, process for their preparation, and medicinal composition containing same

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79603B (ja) * 1982-07-24 1984-10-31 Pfizer
JPS59222418A (ja) * 1983-05-31 1984-12-14 Dainippon Pharmaceut Co Ltd 抗潰瘍剤
US4677107A (en) * 1983-05-31 1987-06-30 Dainippon Pharmaceutical Co., Ltd. Anti-peptic ulcer agent
FR2637591B1 (fr) * 1988-10-11 1992-10-23 Synthelabo Derives de quinoleinone, leur preparation et leur application en therapeutique
DK0385237T3 (da) * 1989-03-03 1994-07-25 Dainippon Pharmaceutical Co 2-(1-Piperazinyl)-4-phenylcycloalkanopyridinderivater, fremgangsmåde til fremstilling deraf og farmaceutisk præparat indeholdende dem
CA2144669A1 (en) * 1994-03-29 1995-09-30 Kozo Akasaka Biphenyl derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3542785A (en) * 1967-05-15 1970-11-24 Ciba Geigy Corp 2-hydroxy-4-aryl-quinolines
US3576809A (en) * 1968-05-06 1971-04-27 Miles Lab 2-substituted derivatives of 6-methoxyquinoline
US3668207A (en) * 1970-01-22 1972-06-06 Ciba Geigy Corp 2-amino-4-aryl-quinolines
US3737540A (en) * 1972-02-14 1973-06-05 Miles Lab Composition for suppressing the tremor of parkinson's syndrome

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003198A1 (en) * 1984-11-27 1986-06-05 Dainippon Pharmaceutical Co., Ltd. 2-(1-piperazinyl)-4-substituted phenylquinoline derivatives, process for their preparation, and medicinal composition containing same

Also Published As

Publication number Publication date
FR2421173A1 (fr) 1979-10-26
JPS6344749B2 (ja) 1988-09-06
US4237135A (en) 1980-12-02
DE2912414A1 (de) 1979-10-04
IT1121456B (it) 1986-04-02
GB2017698A (en) 1979-10-10
GB2017698B (en) 1982-08-04
DE2912414C2 (ja) 1988-03-17
FR2421173B1 (ja) 1983-01-28
IT7967658A0 (it) 1979-03-29

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