DE2828074A1 - Form ii der 2-(4-chlorphenyl)- alpha -methyl-5-benzoxazolyl-essigsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel - Google Patents

Form ii der 2-(4-chlorphenyl)- alpha -methyl-5-benzoxazolyl-essigsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel

Info

Publication number
DE2828074A1
DE2828074A1 DE19782828074 DE2828074A DE2828074A1 DE 2828074 A1 DE2828074 A1 DE 2828074A1 DE 19782828074 DE19782828074 DE 19782828074 DE 2828074 A DE2828074 A DE 2828074A DE 2828074 A1 DE2828074 A1 DE 2828074A1
Authority
DE
Germany
Prior art keywords
benoxaprofen
methyl
acetic acid
benzoxazolyl
chlorphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19782828074
Other languages
German (de)
English (en)
Inventor
Terence Allan Hicks
Roy Sherlock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of DE2828074A1 publication Critical patent/DE2828074A1/de
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57Aryl or substituted aryl radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19782828074 1977-06-28 1978-06-27 Form ii der 2-(4-chlorphenyl)- alpha -methyl-5-benzoxazolyl-essigsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel Ceased DE2828074A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB26907/77A GB1590587A (en) 1977-06-28 1977-06-28 Benoxaprofen

Publications (1)

Publication Number Publication Date
DE2828074A1 true DE2828074A1 (de) 1979-01-11

Family

ID=10251100

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19782828074 Ceased DE2828074A1 (de) 1977-06-28 1978-06-27 Form ii der 2-(4-chlorphenyl)- alpha -methyl-5-benzoxazolyl-essigsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
DE7878300082T Expired DE2862013D1 (en) 1977-06-28 1978-06-27 A novel crystalline form of benoxaprofen, methods of preparation thereof and pharmaceutical formulations containing said novel form

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE7878300082T Expired DE2862013D1 (en) 1977-06-28 1978-06-27 A novel crystalline form of benoxaprofen, methods of preparation thereof and pharmaceutical formulations containing said novel form

Country Status (17)

Country Link
EP (1) EP0000276B1 (enExample)
JP (1) JPS5411224A (enExample)
AT (1) AT360008B (enExample)
AU (1) AU518403B2 (enExample)
BE (1) BE868522A (enExample)
CH (1) CH631449A5 (enExample)
DE (2) DE2828074A1 (enExample)
DK (1) DK145419C (enExample)
FI (1) FI69453C (enExample)
FR (1) FR2396004A1 (enExample)
GB (1) GB1590587A (enExample)
IE (1) IE47009B1 (enExample)
IL (1) IL55015A (enExample)
IT (1) IT1105065B (enExample)
LU (1) LU79879A1 (enExample)
NZ (1) NZ187674A (enExample)
ZA (1) ZA783660B (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2324443A1 (de) * 1972-05-18 1973-11-29 Lilly Industries Ltd Benzoxazol-derivate und verfahren zu ihrer herstellung
DE2431255A1 (de) 1973-06-29 1975-01-23 Hoffmann La Roche Amino-niedere-alkylaether des phenolischen hydroxylrestes eines opiumalkaloides, verfahren zu ihrer herstellung und ihre verwendung
DE2728323A1 (de) * 1976-06-23 1978-01-19 Int Pharmaceutical Patents Co Optisch aktive derivate von benzoxazolylpropionsaeure, verfahren zu ihrer herstellung und arzneimittel
DE2931255A1 (de) * 1978-08-04 1980-02-28 Ravizza Spa Verfahren zur herstellung von benzoxazolylpropionsaeurederivaten
DE3325672A1 (de) * 1982-07-19 1984-01-19 Ravizza S.p.A., Muggio, Milano Verfahren zur herstellung von benzoxazolylpropionsaeure-derivaten

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA83620C2 (ru) 2001-12-05 2008-08-11 Уайт Замещенные бензоксазолы и их аналоги как эстрогенные агенты
WO2021116820A1 (en) * 2019-12-10 2021-06-17 Aurobindo Pharma Limited An improved process for the preparation of benoxaprofen
DE102022117931A1 (de) 2022-07-18 2024-01-18 HUECK System GmbH & Co. KG Profilanordnung mit wärmedämmung
US11981645B1 (en) 2023-10-10 2024-05-14 King Faisal University N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as antimicrobial compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1435721A (en) * 1972-05-18 1976-05-12 Lilly Industries Ltd Benzoxazole derivatives
GB1488003A (en) * 1973-10-23 1977-10-05 Lilly Industries Ltd 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals
US4087437A (en) * 1976-09-07 1978-05-02 Eli Lilly And Company 2-Phenyl-5-benzoxazolylalkanoic acid purification process

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Journal Med. Chem. Vol. 18 (1975), S. 55 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2324443A1 (de) * 1972-05-18 1973-11-29 Lilly Industries Ltd Benzoxazol-derivate und verfahren zu ihrer herstellung
DE2431255A1 (de) 1973-06-29 1975-01-23 Hoffmann La Roche Amino-niedere-alkylaether des phenolischen hydroxylrestes eines opiumalkaloides, verfahren zu ihrer herstellung und ihre verwendung
DE2431255C3 (de) 1973-06-29 1980-11-06 F. Hoffmann-La Roche & Co Ag, Basel (Schweiz) Amino-alkyläther des Morphins, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung eines Reagens zur antikörperspezifischen Bestimmung von Opiumalkaloiden
DE2728323A1 (de) * 1976-06-23 1978-01-19 Int Pharmaceutical Patents Co Optisch aktive derivate von benzoxazolylpropionsaeure, verfahren zu ihrer herstellung und arzneimittel
DE2931255A1 (de) * 1978-08-04 1980-02-28 Ravizza Spa Verfahren zur herstellung von benzoxazolylpropionsaeurederivaten
DE3325672A1 (de) * 1982-07-19 1984-01-19 Ravizza S.p.A., Muggio, Milano Verfahren zur herstellung von benzoxazolylpropionsaeure-derivaten

Also Published As

Publication number Publication date
NZ187674A (en) 1980-11-14
DE2862013D1 (en) 1982-10-28
EP0000276A1 (en) 1979-01-10
IL55015A0 (en) 1978-08-31
DK287578A (da) 1978-12-29
DK145419B (da) 1982-11-15
FR2396004B1 (enExample) 1981-09-18
CH631449A5 (fr) 1982-08-13
LU79879A1 (enExample) 1978-12-07
ATA466178A (de) 1980-05-15
AU3750178A (en) 1980-01-03
IT1105065B (it) 1985-10-28
IE47009B1 (en) 1983-11-30
FI69453B (fi) 1985-10-31
JPS6231714B2 (enExample) 1987-07-09
FI782043A7 (fi) 1978-12-29
BE868522A (fr) 1978-12-27
IL55015A (en) 1981-11-30
AT360008B (de) 1980-12-10
FR2396004A1 (fr) 1979-01-26
GB1590587A (en) 1981-06-03
AU518403B2 (en) 1981-10-01
FI69453C (fi) 1986-02-10
IE781277L (en) 1978-12-28
DK145419C (da) 1983-04-18
JPS5411224A (en) 1979-01-27
EP0000276B1 (en) 1982-09-01
IT7850048A0 (it) 1978-06-27
ZA783660B (en) 1979-06-27

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: TUERK, D., DIPL.-CHEM. DR.RER.NAT. GILLE, C., DIPL

8131 Rejection