DE2828074A1 - Form ii der 2-(4-chlorphenyl)- alpha -methyl-5-benzoxazolyl-essigsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel - Google Patents
Form ii der 2-(4-chlorphenyl)- alpha -methyl-5-benzoxazolyl-essigsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittelInfo
- Publication number
- DE2828074A1 DE2828074A1 DE19782828074 DE2828074A DE2828074A1 DE 2828074 A1 DE2828074 A1 DE 2828074A1 DE 19782828074 DE19782828074 DE 19782828074 DE 2828074 A DE2828074 A DE 2828074A DE 2828074 A1 DE2828074 A1 DE 2828074A1
- Authority
- DE
- Germany
- Prior art keywords
- benoxaprofen
- methyl
- acetic acid
- benzoxazolyl
- chlorphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB26907/77A GB1590587A (en) | 1977-06-28 | 1977-06-28 | Benoxaprofen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2828074A1 true DE2828074A1 (de) | 1979-01-11 |
Family
ID=10251100
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19782828074 Ceased DE2828074A1 (de) | 1977-06-28 | 1978-06-27 | Form ii der 2-(4-chlorphenyl)- alpha -methyl-5-benzoxazolyl-essigsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel |
| DE7878300082T Expired DE2862013D1 (en) | 1977-06-28 | 1978-06-27 | A novel crystalline form of benoxaprofen, methods of preparation thereof and pharmaceutical formulations containing said novel form |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE7878300082T Expired DE2862013D1 (en) | 1977-06-28 | 1978-06-27 | A novel crystalline form of benoxaprofen, methods of preparation thereof and pharmaceutical formulations containing said novel form |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0000276B1 (enExample) |
| JP (1) | JPS5411224A (enExample) |
| AT (1) | AT360008B (enExample) |
| AU (1) | AU518403B2 (enExample) |
| BE (1) | BE868522A (enExample) |
| CH (1) | CH631449A5 (enExample) |
| DE (2) | DE2828074A1 (enExample) |
| DK (1) | DK145419C (enExample) |
| FI (1) | FI69453C (enExample) |
| FR (1) | FR2396004A1 (enExample) |
| GB (1) | GB1590587A (enExample) |
| IE (1) | IE47009B1 (enExample) |
| IL (1) | IL55015A (enExample) |
| IT (1) | IT1105065B (enExample) |
| LU (1) | LU79879A1 (enExample) |
| NZ (1) | NZ187674A (enExample) |
| ZA (1) | ZA783660B (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2324443A1 (de) * | 1972-05-18 | 1973-11-29 | Lilly Industries Ltd | Benzoxazol-derivate und verfahren zu ihrer herstellung |
| DE2431255A1 (de) | 1973-06-29 | 1975-01-23 | Hoffmann La Roche | Amino-niedere-alkylaether des phenolischen hydroxylrestes eines opiumalkaloides, verfahren zu ihrer herstellung und ihre verwendung |
| DE2728323A1 (de) * | 1976-06-23 | 1978-01-19 | Int Pharmaceutical Patents Co | Optisch aktive derivate von benzoxazolylpropionsaeure, verfahren zu ihrer herstellung und arzneimittel |
| DE2931255A1 (de) * | 1978-08-04 | 1980-02-28 | Ravizza Spa | Verfahren zur herstellung von benzoxazolylpropionsaeurederivaten |
| DE3325672A1 (de) * | 1982-07-19 | 1984-01-19 | Ravizza S.p.A., Muggio, Milano | Verfahren zur herstellung von benzoxazolylpropionsaeure-derivaten |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA83620C2 (ru) | 2001-12-05 | 2008-08-11 | Уайт | Замещенные бензоксазолы и их аналоги как эстрогенные агенты |
| WO2021116820A1 (en) * | 2019-12-10 | 2021-06-17 | Aurobindo Pharma Limited | An improved process for the preparation of benoxaprofen |
| DE102022117931A1 (de) | 2022-07-18 | 2024-01-18 | HUECK System GmbH & Co. KG | Profilanordnung mit wärmedämmung |
| US11981645B1 (en) | 2023-10-10 | 2024-05-14 | King Faisal University | N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as antimicrobial compound |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1435721A (en) * | 1972-05-18 | 1976-05-12 | Lilly Industries Ltd | Benzoxazole derivatives |
| GB1488003A (en) * | 1973-10-23 | 1977-10-05 | Lilly Industries Ltd | 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals |
| US4087437A (en) * | 1976-09-07 | 1978-05-02 | Eli Lilly And Company | 2-Phenyl-5-benzoxazolylalkanoic acid purification process |
-
1977
- 1977-06-28 GB GB26907/77A patent/GB1590587A/en not_active Expired
-
1978
- 1978-06-26 CH CH691778A patent/CH631449A5/fr not_active IP Right Cessation
- 1978-06-26 NZ NZ187674A patent/NZ187674A/xx unknown
- 1978-06-26 DK DK287578A patent/DK145419C/da not_active IP Right Cessation
- 1978-06-27 AU AU37501/78A patent/AU518403B2/en not_active Expired
- 1978-06-27 IT IT50048/78A patent/IT1105065B/it active
- 1978-06-27 IE IE1277/78A patent/IE47009B1/en not_active IP Right Cessation
- 1978-06-27 AT AT466178A patent/AT360008B/de not_active IP Right Cessation
- 1978-06-27 LU LU79879A patent/LU79879A1/xx unknown
- 1978-06-27 DE DE19782828074 patent/DE2828074A1/de not_active Ceased
- 1978-06-27 ZA ZA00783660A patent/ZA783660B/xx unknown
- 1978-06-27 IL IL55015A patent/IL55015A/xx unknown
- 1978-06-27 FR FR7819091A patent/FR2396004A1/fr active Granted
- 1978-06-27 EP EP78300082A patent/EP0000276B1/en not_active Expired
- 1978-06-27 BE BE6046515A patent/BE868522A/xx not_active IP Right Cessation
- 1978-06-27 DE DE7878300082T patent/DE2862013D1/de not_active Expired
- 1978-06-27 FI FI782043A patent/FI69453C/fi not_active IP Right Cessation
- 1978-06-27 JP JP7795178A patent/JPS5411224A/ja active Granted
Non-Patent Citations (1)
| Title |
|---|
| Journal Med. Chem. Vol. 18 (1975), S. 55 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2324443A1 (de) * | 1972-05-18 | 1973-11-29 | Lilly Industries Ltd | Benzoxazol-derivate und verfahren zu ihrer herstellung |
| DE2431255A1 (de) | 1973-06-29 | 1975-01-23 | Hoffmann La Roche | Amino-niedere-alkylaether des phenolischen hydroxylrestes eines opiumalkaloides, verfahren zu ihrer herstellung und ihre verwendung |
| DE2431255C3 (de) | 1973-06-29 | 1980-11-06 | F. Hoffmann-La Roche & Co Ag, Basel (Schweiz) | Amino-alkyläther des Morphins, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung eines Reagens zur antikörperspezifischen Bestimmung von Opiumalkaloiden |
| DE2728323A1 (de) * | 1976-06-23 | 1978-01-19 | Int Pharmaceutical Patents Co | Optisch aktive derivate von benzoxazolylpropionsaeure, verfahren zu ihrer herstellung und arzneimittel |
| DE2931255A1 (de) * | 1978-08-04 | 1980-02-28 | Ravizza Spa | Verfahren zur herstellung von benzoxazolylpropionsaeurederivaten |
| DE3325672A1 (de) * | 1982-07-19 | 1984-01-19 | Ravizza S.p.A., Muggio, Milano | Verfahren zur herstellung von benzoxazolylpropionsaeure-derivaten |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ187674A (en) | 1980-11-14 |
| DE2862013D1 (en) | 1982-10-28 |
| EP0000276A1 (en) | 1979-01-10 |
| IL55015A0 (en) | 1978-08-31 |
| DK287578A (da) | 1978-12-29 |
| DK145419B (da) | 1982-11-15 |
| FR2396004B1 (enExample) | 1981-09-18 |
| CH631449A5 (fr) | 1982-08-13 |
| LU79879A1 (enExample) | 1978-12-07 |
| ATA466178A (de) | 1980-05-15 |
| AU3750178A (en) | 1980-01-03 |
| IT1105065B (it) | 1985-10-28 |
| IE47009B1 (en) | 1983-11-30 |
| FI69453B (fi) | 1985-10-31 |
| JPS6231714B2 (enExample) | 1987-07-09 |
| FI782043A7 (fi) | 1978-12-29 |
| BE868522A (fr) | 1978-12-27 |
| IL55015A (en) | 1981-11-30 |
| AT360008B (de) | 1980-12-10 |
| FR2396004A1 (fr) | 1979-01-26 |
| GB1590587A (en) | 1981-06-03 |
| AU518403B2 (en) | 1981-10-01 |
| FI69453C (fi) | 1986-02-10 |
| IE781277L (en) | 1978-12-28 |
| DK145419C (da) | 1983-04-18 |
| JPS5411224A (en) | 1979-01-27 |
| EP0000276B1 (en) | 1982-09-01 |
| IT7850048A0 (it) | 1978-06-27 |
| ZA783660B (en) | 1979-06-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3529529C2 (enExample) | ||
| DE69104991T2 (de) | Mometason-furoate-monohydrat, verfahren zu seiner herstellung und das enthaltende pharmazeutische zusammensetzungen. | |
| DE69905176T2 (de) | Verfahren zur herstellung von clarithromycinkristallen der form ii | |
| DE69322087T2 (de) | Neues kristall von heterozyclischen bis(phosphonsäure) monohydrat-derivat | |
| DE2748825A1 (de) | Neue carbonsaeurederivate und deren verwendung als mittel gegen hyperlipaemie | |
| LU84919A1 (de) | Medizinisches praeparat enthaltend pirprofen | |
| DE2828074A1 (de) | Form ii der 2-(4-chlorphenyl)- alpha -methyl-5-benzoxazolyl-essigsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel | |
| DD202573A5 (de) | Verfahren zur herstellung von 1-aethyl-6-fluor-1,4dihydro-4-oxo-7-(1-piperazinyl)-1,8 naphthyridin-3-carbonsaeure | |
| WO1998047872A1 (de) | Verfahren zur herstellung von reinem flupirtin-maleat und dessen modifikation a | |
| DE1966640A1 (de) | Verfahren zur herstellung von 4- und/ oder 4,6-substituierten pyrazolo (3,4-d)pyrimidinen | |
| DE3017977A1 (de) | Neue substituierte 2(3h)-benzothiazolone | |
| DE1518354B2 (de) | Aminophenylsalicylate, Verfahren zu deren Herstellung und Arzneimittel | |
| DE830994C (de) | Verfahren zur Herstellung von Doppelsalzen des Streptomycins | |
| DE2317179C2 (de) | Verfahren zur Herstellung der relativ wasserunlöslichen kristallinen Form von Cefalexinmonohydrat | |
| DE69820301T2 (de) | Neue krystalline polymorphe form von 1-methyl-5-p-toluoylpyrrol-2-acetamidoessigsäure guaiacyl ester (med 15) | |
| DE3246135C2 (de) | Kristallines gamma-Bestatin und Verfahren zu seiner Herstellung | |
| DE2520488A1 (de) | Verfahren zur gewinnung reiner 3alpha,7alpha-dihydroxy-5beta-cholansaeure | |
| DD157256A5 (de) | Verfahren zur herstellung einer neuen kristallinen form von n-2-(6-methoxy)benzothiazolyl-n'-phenyl-harnstoff | |
| DE831549C (de) | Verfahren zur Herstellung von Lactoflavinmonophosphorsaeureester | |
| DE1924451C3 (de) | Verfahren zur Herstellung von 2-Methylamino-5-phenyl-3H-1,4benzodiazepin-4-oxydderivaten | |
| DE2312460C3 (de) | Verfahren zur Herstellung von 3-Acetamido-5-aminobenzoesaure | |
| CH641174A5 (de) | Verfahren zur herstellung von n-(4'-chlor-3'-sulfamoyl-benzolsulfonyl)-n-methyl-2-aminomethyl-2-methyl-tetrahydrofuran. | |
| DE1958329A1 (de) | Verfahren zur Reinigung von Cephaloglycinantibiotica | |
| AT221501B (de) | Verfahren zur Herstellung der neuen 4-Chlor-3-sulfamyl-benzoesäure und deren Alkalisalze | |
| DE2950345A1 (de) | Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| 8128 | New person/name/address of the agent |
Representative=s name: TUERK, D., DIPL.-CHEM. DR.RER.NAT. GILLE, C., DIPL |
|
| 8131 | Rejection |