IE781277L - Benzoxaprofen - Google Patents
BenzoxaprofenInfo
- Publication number
- IE781277L IE781277L IE781277A IE127778A IE781277L IE 781277 L IE781277 L IE 781277L IE 781277 A IE781277 A IE 781277A IE 127778 A IE127778 A IE 127778A IE 781277 L IE781277 L IE 781277L
- Authority
- IE
- Ireland
- Prior art keywords
- benoxaprofen
- novel
- pharmaceutical formulations
- benzoxaprofen
- mastastable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A novel crystalling form of benoxaprofen, methods of preparation thereof and pharmaceutical formulations containing said novel form. A thermodynamically stable polymorph of benoxaprofen, an antiinflammatory agent of the structural formula: <CHEM> This stable polymorphic form, which can be prepared from the mastastable form by thermal treatment or crystallisation from a solution, is used in pharmaceutical formulations.
[EP0000276A1]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB26907/77A GB1590587A (en) | 1977-06-28 | 1977-06-28 | Benoxaprofen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE781277L true IE781277L (en) | 1978-12-28 |
| IE47009B1 IE47009B1 (en) | 1983-11-30 |
Family
ID=10251100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1277/78A IE47009B1 (en) | 1977-06-28 | 1978-06-27 | Improvements in or relating to benoxaprofen |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0000276B1 (en) |
| JP (1) | JPS5411224A (en) |
| AT (1) | AT360008B (en) |
| AU (1) | AU518403B2 (en) |
| BE (1) | BE868522A (en) |
| CH (1) | CH631449A5 (en) |
| DE (2) | DE2828074A1 (en) |
| DK (1) | DK145419C (en) |
| FI (1) | FI69453C (en) |
| FR (1) | FR2396004A1 (en) |
| GB (1) | GB1590587A (en) |
| IE (1) | IE47009B1 (en) |
| IL (1) | IL55015A (en) |
| IT (1) | IT1105065B (en) |
| LU (1) | LU79879A1 (en) |
| NZ (1) | NZ187674A (en) |
| ZA (1) | ZA783660B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1435721A (en) * | 1972-05-18 | 1976-05-12 | Lilly Industries Ltd | Benzoxazole derivatives |
| US3888864A (en) | 1973-06-29 | 1975-06-10 | Hoffmann La Roche | Amino lower alkyl ether derivatives of opium alkaloids |
| GB1495488A (en) * | 1976-06-23 | 1977-12-21 | Ippco Int Pharma Patents Co Es | Optically active 2-(2-phenyl-5-benzoxazolyl)propionic acids |
| IT1099589B (en) * | 1978-08-04 | 1985-09-18 | Ravizza Spa | PROCESS FOR THE PREPARATION OF PROPIONIC BENZOXAZOLYL ACID DERIVATIVES |
| IT1157295B (en) * | 1982-07-19 | 1987-02-11 | Ravizza Spa | PROCESS PERFECTED FOR THE PREPARATION OF DERIVATIVES OF BENZOXAZOLYL PROPIONIC ACID |
| UA83620C2 (en) | 2001-12-05 | 2008-08-11 | Уайт | Substituted benzoxazoles and analogues as estrogenic agents |
| WO2021116820A1 (en) * | 2019-12-10 | 2021-06-17 | Aurobindo Pharma Limited | An improved process for the preparation of benoxaprofen |
| DE102022117931A1 (en) | 2022-07-18 | 2024-01-18 | HUECK System GmbH & Co. KG | PROFILE ARRANGEMENT WITH THERMAL INSULATION |
| US11981645B1 (en) | 2023-10-10 | 2024-05-14 | King Faisal University | N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as antimicrobial compound |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1435721A (en) * | 1972-05-18 | 1976-05-12 | Lilly Industries Ltd | Benzoxazole derivatives |
| GB1488003A (en) * | 1973-10-23 | 1977-10-05 | Lilly Industries Ltd | 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals |
| US4087437A (en) * | 1976-09-07 | 1978-05-02 | Eli Lilly And Company | 2-Phenyl-5-benzoxazolylalkanoic acid purification process |
-
1977
- 1977-06-28 GB GB26907/77A patent/GB1590587A/en not_active Expired
-
1978
- 1978-06-26 NZ NZ187674A patent/NZ187674A/en unknown
- 1978-06-26 DK DK287578A patent/DK145419C/en not_active IP Right Cessation
- 1978-06-26 CH CH691778A patent/CH631449A5/en not_active IP Right Cessation
- 1978-06-27 AU AU37501/78A patent/AU518403B2/en not_active Expired
- 1978-06-27 EP EP78300082A patent/EP0000276B1/en not_active Expired
- 1978-06-27 DE DE19782828074 patent/DE2828074A1/en not_active Ceased
- 1978-06-27 FR FR7819091A patent/FR2396004A1/en active Granted
- 1978-06-27 IL IL55015A patent/IL55015A/en unknown
- 1978-06-27 IE IE1277/78A patent/IE47009B1/en not_active IP Right Cessation
- 1978-06-27 BE BE6046515A patent/BE868522A/en not_active IP Right Cessation
- 1978-06-27 DE DE7878300082T patent/DE2862013D1/en not_active Expired
- 1978-06-27 ZA ZA00783660A patent/ZA783660B/en unknown
- 1978-06-27 LU LU79879A patent/LU79879A1/xx unknown
- 1978-06-27 FI FI782043A patent/FI69453C/en not_active IP Right Cessation
- 1978-06-27 JP JP7795178A patent/JPS5411224A/en active Granted
- 1978-06-27 AT AT466178A patent/AT360008B/en not_active IP Right Cessation
- 1978-06-27 IT IT50048/78A patent/IT1105065B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| DK287578A (en) | 1978-12-29 |
| FI69453C (en) | 1986-02-10 |
| IE47009B1 (en) | 1983-11-30 |
| AU3750178A (en) | 1980-01-03 |
| JPS6231714B2 (en) | 1987-07-09 |
| AT360008B (en) | 1980-12-10 |
| FR2396004A1 (en) | 1979-01-26 |
| EP0000276B1 (en) | 1982-09-01 |
| IT7850048A0 (en) | 1978-06-27 |
| ATA466178A (en) | 1980-05-15 |
| FR2396004B1 (en) | 1981-09-18 |
| FI782043A (en) | 1978-12-29 |
| DE2828074A1 (en) | 1979-01-11 |
| LU79879A1 (en) | 1978-12-07 |
| CH631449A5 (en) | 1982-08-13 |
| DK145419B (en) | 1982-11-15 |
| DE2862013D1 (en) | 1982-10-28 |
| GB1590587A (en) | 1981-06-03 |
| AU518403B2 (en) | 1981-10-01 |
| DK145419C (en) | 1983-04-18 |
| FI69453B (en) | 1985-10-31 |
| IL55015A (en) | 1981-11-30 |
| EP0000276A1 (en) | 1979-01-10 |
| IL55015A0 (en) | 1978-08-31 |
| IT1105065B (en) | 1985-10-28 |
| NZ187674A (en) | 1980-11-14 |
| ZA783660B (en) | 1979-06-27 |
| JPS5411224A (en) | 1979-01-27 |
| BE868522A (en) | 1978-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |