DE2823916A1 - Verfahren zur selektiven bestimmung von lebensfaehigen soma- und mikroben-zellen - Google Patents
Verfahren zur selektiven bestimmung von lebensfaehigen soma- und mikroben-zellenInfo
- Publication number
- DE2823916A1 DE2823916A1 DE19782823916 DE2823916A DE2823916A1 DE 2823916 A1 DE2823916 A1 DE 2823916A1 DE 19782823916 DE19782823916 DE 19782823916 DE 2823916 A DE2823916 A DE 2823916A DE 2823916 A1 DE2823916 A1 DE 2823916A1
- Authority
- DE
- Germany
- Prior art keywords
- atp
- cells
- sample
- concentration
- release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 230000001580 bacterial effect Effects 0.000 claims description 31
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- 241000894006 Bacteria Species 0.000 claims description 26
- 230000029918 bioluminescence Effects 0.000 claims description 21
- 238000005415 bioluminescence Methods 0.000 claims description 21
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- 102000007347 Apyrase Human genes 0.000 claims description 14
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- IGXWBGJHJZYPQS-SSDOTTSWSA-N D-Luciferin Chemical compound OC(=O)[C@H]1CSC(C=2SC3=CC=C(O)C=C3N=2)=N1 IGXWBGJHJZYPQS-SSDOTTSWSA-N 0.000 claims description 7
- 239000012528 membrane Substances 0.000 claims description 6
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- 239000011780 sodium chloride Substances 0.000 claims description 3
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- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 2
- 108091006112 ATPases Proteins 0.000 claims 1
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- 244000061456 Solanum tuberosum Species 0.000 claims 1
- ZKHQWZAMYRWXGA-KQYNXXCUSA-J ATP(4-) Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-J 0.000 description 70
- ZKHQWZAMYRWXGA-UHFFFAOYSA-N Adenosine triphosphate Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O ZKHQWZAMYRWXGA-UHFFFAOYSA-N 0.000 description 70
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- 229910019142 PO4 Inorganic materials 0.000 description 3
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 3
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- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 3
- 235000021317 phosphate Nutrition 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- -1 urine Substances 0.000 description 3
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- 241000192125 Firmicutes Species 0.000 description 2
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
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- XTWYTFMLZFPYCI-KQYNXXCUSA-N 5'-adenylphosphoric acid Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O XTWYTFMLZFPYCI-KQYNXXCUSA-N 0.000 description 1
- 201000004538 Bacteriuria Diseases 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 241000195651 Chlorella sp. Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- UDMBCSSLTHHNCD-UHFFFAOYSA-N Coenzym Q(11) Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(O)=O)C(O)C1O UDMBCSSLTHHNCD-UHFFFAOYSA-N 0.000 description 1
- 241000588722 Escherichia Species 0.000 description 1
- YTNIXZGTHTVJBW-SCRDCRAPSA-N FMNH2 Chemical compound OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2NC2=C1NC(=O)NC2=O YTNIXZGTHTVJBW-SCRDCRAPSA-N 0.000 description 1
- XKMLYUALXHKNFT-UUOKFMHZSA-N Guanosine-5'-triphosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O XKMLYUALXHKNFT-UUOKFMHZSA-N 0.000 description 1
- HAEJPQIATWHALX-KQYNXXCUSA-J ITP(4-) Chemical compound O[C@@H]1[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)O[C@H]1N1C(N=CNC2=O)=C2N=C1 HAEJPQIATWHALX-KQYNXXCUSA-J 0.000 description 1
- MSFSPUZXLOGKHJ-UHFFFAOYSA-N Muraminsaeure Natural products OC(=O)C(C)OC1C(N)C(O)OC(CO)C1O MSFSPUZXLOGKHJ-UHFFFAOYSA-N 0.000 description 1
- 108010013639 Peptidoglycan Proteins 0.000 description 1
- CYTYCFOTNPOANT-UHFFFAOYSA-N Perchloroethylene Chemical compound ClC(Cl)=C(Cl)Cl CYTYCFOTNPOANT-UHFFFAOYSA-N 0.000 description 1
- 241000607568 Photobacterium Species 0.000 description 1
- 239000002202 Polyethylene glycol Chemical class 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical compound OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 description 1
- XJLXINKUBYWONI-DQQFMEOOSA-N [[(2r,3r,4r,5r)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2s,3r,4s,5s)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate Chemical compound NC(=O)C1=CC=C[N+]([C@@H]2[C@H]([C@@H](O)[C@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](OP(O)(O)=O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 XJLXINKUBYWONI-DQQFMEOOSA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
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- 150000004985 diamines Chemical class 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
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- 230000008030 elimination Effects 0.000 description 1
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- 230000007613 environmental effect Effects 0.000 description 1
- 239000002532 enzyme inhibitor Substances 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
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- 238000002796 luminescence method Methods 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
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- 239000002609 medium Substances 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 210000000663 muscle cell Anatomy 0.000 description 1
- KRGPXXHMOXVMMM-UHFFFAOYSA-N nicotianamine Natural products OC(=O)C(N)CCNC(C(O)=O)CCN1CCC1C(O)=O KRGPXXHMOXVMMM-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920001223 polyethylene glycol Chemical class 0.000 description 1
- 229920000151 polyglycol Polymers 0.000 description 1
- 239000010695 polyglycol Substances 0.000 description 1
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- 238000002360 preparation method Methods 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
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- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/008—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions for determining co-enzymes or co-factors, e.g. NAD, ATP
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/82—Subcellular parts of microorganisms
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB22992/77A GB1604249A (en) | 1977-05-31 | 1977-05-31 | Selective measurement of somatic and microbial cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2823916A1 true DE2823916A1 (de) | 1978-12-07 |
| DE2823916C2 DE2823916C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-12-06 |
Family
ID=10188370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19782823916 Granted DE2823916A1 (de) | 1977-05-31 | 1978-05-31 | Verfahren zur selektiven bestimmung von lebensfaehigen soma- und mikroben-zellen |
Country Status (7)
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0025351A1 (en) * | 1979-09-05 | 1981-03-18 | Dynatech Ag | Detection of bacteria in urine |
| US4314026A (en) * | 1980-03-31 | 1982-02-02 | Institut National De La Sante Et De La Recherche Medicale | Process for determining the complement-dependent cytotoxicity mediated by anti-HLA antibodies by means of ATP determination and device for ATP determination |
| EP0309184A3 (en) * | 1987-09-22 | 1990-04-18 | Lumac Bv | Method for atp extraction |
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| WO1988007584A1 (en) * | 1987-03-23 | 1988-10-06 | New Horizons Diagnostics Corporation | Method and apparatus for detection and quantification of bacteria |
| DK258787D0 (da) * | 1987-05-21 | 1987-05-21 | Foss Electric As N | Fremgangsmaade til bestemmelse af bakteriekoncentration i en proeve |
| JPH0257197A (ja) * | 1988-02-03 | 1990-02-26 | Japan Organo Co Ltd | 生菌の定量法 |
| US5354663A (en) * | 1988-05-04 | 1994-10-11 | Charm Sciences, Inc. | Microbial inhibition test kit and method |
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| US5426035A (en) * | 1992-03-18 | 1995-06-20 | Microbics Corporation | Method of compensating toxicity test data for the measured toxicity of a reference sample |
| FI93742C (fi) * | 1992-10-23 | 1995-05-26 | Elias Hakalehto | Menetelmä ja laite solujen osoittamiseksi |
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| DE4306184A1 (de) * | 1993-02-27 | 1994-09-01 | Joerg Doerpinghaus | Vorrichtung zum kontinuierlichen Erfassen physikalischer und/oder chemischer Parameter von Flüssigkeiten |
| GB9308411D0 (en) * | 1993-04-23 | 1993-06-09 | Celsis Ltd | Detection of biological material |
| GB2288232A (en) * | 1994-04-06 | 1995-10-11 | Brf International | Photosensitive derivatives of ATP as assay control standards |
| DE19625137A1 (de) * | 1996-06-24 | 1998-01-08 | Basf Ag | Verwendung eines Bioluminszenz-Tests zum Nachweis von Mikroorganismen in Dispersionen, die Polymere und/oder Pigmente enthalten |
| GB9626932D0 (en) * | 1996-12-24 | 1997-02-12 | Lumitech Limited | Assay methods and kits therefor |
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| US20050089918A1 (en) * | 1998-02-23 | 2005-04-28 | Amersham Biosciences Uk Limited | In-situ cell extraction and assay method |
| US6703211B1 (en) | 1998-03-13 | 2004-03-09 | Promega Corporation | Cellular detection by providing high energy phosphate donor other than ADP to produce ATP |
| US6391551B1 (en) | 1998-03-13 | 2002-05-21 | Promega Corporation | Detection of nucleic acid hybrids |
| US7090975B2 (en) | 1998-03-13 | 2006-08-15 | Promega Corporation | Pyrophosphorolysis and incorporation of nucleotide method for nucleic acid detection |
| US6335162B1 (en) | 1998-03-13 | 2002-01-01 | Promega Corporation | Nucleic acid detection |
| US6270974B1 (en) | 1998-03-13 | 2001-08-07 | Promega Corporation | Exogenous nucleic acid detection |
| US6268146B1 (en) | 1998-03-13 | 2001-07-31 | Promega Corporation | Analytical methods and materials for nucleic acid detection |
| US6312902B1 (en) | 1998-03-13 | 2001-11-06 | Promega Corporation | Nucleic acid detection |
| US6270973B1 (en) | 1998-03-13 | 2001-08-07 | Promega Corporation | Multiplex method for nucleic acid detection |
| US6235480B1 (en) | 1998-03-13 | 2001-05-22 | Promega Corporation | Detection of nucleic acid hybrids |
| US6242235B1 (en) * | 1998-06-24 | 2001-06-05 | Promega Corp. | Polymerase stabilization by polyethoxylated amine surfactants |
| US6939696B1 (en) * | 1998-08-03 | 2005-09-06 | Becton, Dickinson And Company | Cell disruption method using sonication |
| GB9911095D0 (en) * | 1999-05-13 | 1999-07-14 | Secr Defence | Microbiological test method and reagents |
| GB9916443D0 (en) * | 1999-07-14 | 1999-09-15 | Diagnostic Testing Limited | Method and apparatus |
| GB0002201D0 (en) * | 2000-01-31 | 2000-03-22 | Imperial College | Process |
| DE60118797T2 (de) * | 2000-09-13 | 2007-01-18 | Merck Patent Gmbh | Verfahren zur detektion und messung der biomasse |
| US6660489B2 (en) | 2000-12-01 | 2003-12-09 | Becton, Dickinson And Company | ATP extraction method |
| US7083911B2 (en) * | 2001-02-16 | 2006-08-01 | Promega Corporation | Method for detection of ATP |
| US7494781B1 (en) * | 2003-05-12 | 2009-02-24 | Charm Sciences, Inc. | Sensitive method for detecting low levels of ATP |
| US7132249B1 (en) | 2003-05-12 | 2006-11-07 | Charm Sciences, Inc. | Method of determining allergenic food on surfaces |
| EP1660508A2 (en) * | 2003-08-15 | 2006-05-31 | Celsis Inc. | Use of novel compounds to release nucleotides from living cells |
| US20050070701A1 (en) * | 2003-09-29 | 2005-03-31 | Hochstetler Spencer Erich | Detection of living cells in polymers or pigments |
| US7422868B2 (en) * | 2004-07-02 | 2008-09-09 | Promega Corporation | Microbial ATP extraction and detection system |
| FR2876706A1 (fr) * | 2004-10-19 | 2006-04-21 | Testlife Technologies Sarl | Atp-metrie pour detecter et denombrer les virus, utilisation et procede de mise en oeuvre a partir des nucleotides adenyliques des cellules hotes ou du patrimoine genetique des virus |
| GB0513535D0 (en) * | 2005-07-01 | 2005-08-10 | Iseao Technologies Ltd | Improved methods of detecting microbes |
| NL1030525C2 (nl) | 2005-11-25 | 2007-05-29 | Amiris B V | Werkwijze voor het met luminescentie detecteren van ATP in een monster en een computerprogramma daarvoor. |
| US8304206B2 (en) | 2005-12-02 | 2012-11-06 | Sirtris Pharmaceuticals, Inc. | Mass spectrometry assays for identifying compounds that activate deacetylases |
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| WO2009079120A1 (en) * | 2007-12-14 | 2009-06-25 | Genewiz Inc. | Methods for measuring adp |
| WO2010078399A2 (en) | 2008-12-31 | 2010-07-08 | 3M Innovative Properties Company | Sampling devices and methods for concentrating microorganisms |
| CN102325596B (zh) | 2008-12-31 | 2015-04-29 | 3M创新有限公司 | 使用微粒进行的活生物负载检测 |
| EP2519355B1 (en) | 2009-12-30 | 2017-01-25 | 3M Innovative Properties Company | Live bioload detection using microparticles |
| US8845801B2 (en) | 2009-12-30 | 2014-09-30 | Regents Of The University Of Minnesota | Bone cement and method |
| DE102011077238B4 (de) * | 2011-06-09 | 2016-03-31 | Bayerische Motoren Werke Aktiengesellschaft | Verfahren zum Nachweis von Mikroorganismen in einem Hohlraumkonservierungsmittel |
| US9562253B1 (en) | 2012-11-09 | 2017-02-07 | Point Of Care Diagnostics, Llc | Distinguishing between a bacterial and non-bacterial infection at the point of care |
| WO2018088874A1 (ko) * | 2016-11-14 | 2018-05-17 | 주식회사 파이안바이오테크놀로지 | 외래 미토콘드리아를 세포로 전달하는 방법 |
| GB201703383D0 (en) | 2017-03-02 | 2017-04-19 | Gargle Tech Ltd | Testing for particulates |
| US11680877B2 (en) | 2018-09-05 | 2023-06-20 | Hero Scientific Ltd. | Testing for particulates |
| WO2022149135A2 (en) | 2021-01-06 | 2022-07-14 | Hero Scientific Ltd. | Filtration sampling devices |
| EP4308696A1 (en) | 2021-03-16 | 2024-01-24 | ApiRays Bioscience AB | Modified shigella apyrase and uses thereof |
| EP4317451A4 (en) * | 2021-04-01 | 2025-03-12 | Fujirebio Inc. | Method for treating biological sample |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3745090A (en) * | 1970-08-04 | 1973-07-10 | Nasa | Method of detecting and counting bacteria in body fluids |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE337223B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1967-05-23 | 1971-08-02 | Pharmacia Ab | |
| SE343210B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1967-12-20 | 1972-03-06 | Pharmacia Ab | |
| FR2141680A2 (en) * | 1971-04-30 | 1973-01-26 | Nat Aeronautics Spa | Bacteria determination in urine - by bioluminescence reaction of bacterial atp |
| US3930956A (en) * | 1973-10-29 | 1976-01-06 | The Regents Of The University Of Michigan | Method for the genetic detection of microorganisms |
| US3971703A (en) * | 1974-05-31 | 1976-07-27 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Method of detecting and counting bacteria |
| US4014745A (en) * | 1975-04-30 | 1977-03-29 | Nasa | Application of luciferase assay for ATP to antimicrobial drug susceptibility |
| US4144134A (en) * | 1977-01-31 | 1979-03-13 | Vitatect Corp. | Method for detection of bacterial concentration by luminescence |
-
1977
- 1977-05-31 GB GB22992/77A patent/GB1604249A/en not_active Expired
-
1978
- 1978-05-29 SE SE7806164A patent/SE448100B/sv not_active IP Right Cessation
- 1978-05-31 DE DE19782823916 patent/DE2823916A1/de active Granted
- 1978-05-31 CA CA304,548A patent/CA1125152A/en not_active Expired
- 1978-05-31 JP JP53065596A patent/JPS5991900A/ja active Granted
- 1978-05-31 FR FR7816183A patent/FR2401423A1/fr active Granted
-
1979
- 1979-11-30 US US06/098,763 patent/US4303752A/en not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3745090A (en) * | 1970-08-04 | 1973-07-10 | Nasa | Method of detecting and counting bacteria in body fluids |
Non-Patent Citations (1)
| Title |
|---|
| P. Tarkkanen et al.: Freseniles Z. Anal. Chem. 290, S.180, 1978 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0025351A1 (en) * | 1979-09-05 | 1981-03-18 | Dynatech Ag | Detection of bacteria in urine |
| US4314026A (en) * | 1980-03-31 | 1982-02-02 | Institut National De La Sante Et De La Recherche Medicale | Process for determining the complement-dependent cytotoxicity mediated by anti-HLA antibodies by means of ATP determination and device for ATP determination |
| EP0309184A3 (en) * | 1987-09-22 | 1990-04-18 | Lumac Bv | Method for atp extraction |
| WO1992012253A1 (en) * | 1991-01-10 | 1992-07-23 | Amersham International Plc | Method for extraction of intracellular components |
| EP0566010A1 (de) * | 1992-04-13 | 1993-10-20 | BIOLAC GmbH Gesellschaft für industrielle Nutzung von Milchinhaltsstoffen | Verfahren und Analyse-Kit zur Bestimmung der bakteriellen Keimzahl in Molke und Molkeninhaltsstoffen |
| WO1995005483A1 (en) * | 1993-08-18 | 1995-02-23 | The Minister Of Agriculture, Fisheries And Food In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Method and test kits for detection of bacteriophage |
| GB2295893A (en) * | 1993-08-18 | 1996-06-12 | Mini Agriculture & Fisheries | Method and test kits for detection of bacteriophage |
| GB2295893B (en) * | 1993-08-18 | 1997-10-08 | Mini Agriculture & Fisheries | Method and test kits for detection of bacteriophage |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2823916C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-12-06 |
| CA1125152A (en) | 1982-06-08 |
| US4303752A (en) | 1981-12-01 |
| GB1604249A (en) | 1981-12-02 |
| FR2401423B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1983-11-18 |
| JPS624120B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1987-01-28 |
| SE448100B (sv) | 1987-01-19 |
| SE7806164L (sv) | 1978-12-01 |
| JPS5991900A (ja) | 1984-05-26 |
| FR2401423A1 (fr) | 1979-03-23 |
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Representative=s name: TUERK, D., DIPL.-CHEM. DR.RER.NAT. GILLE, C., DIPL |
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Owner name: MINNESOTA MINING AND MANUFACTURING CO., SAINT PAUL |
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