DE2612726C3 - Stabilisierte Urease - Google Patents

Stabilisierte Urease

Info

Publication number
DE2612726C3
DE2612726C3 DE2612726A DE2612726A DE2612726C3 DE 2612726 C3 DE2612726 C3 DE 2612726C3 DE 2612726 A DE2612726 A DE 2612726A DE 2612726 A DE2612726 A DE 2612726A DE 2612726 C3 DE2612726 C3 DE 2612726C3
Authority
DE
Germany
Prior art keywords
urease
ammonia
detection
stabilized
urea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2612726A
Other languages
German (de)
English (en)
Other versions
DE2612726A1 (de
DE2612726B2 (de
Inventor
Ingeborg Dr.Phil.Nat. 8136 Percha Gutmann
Hans 8132 Tutzing Moellering
Albert Dr.Rer.Nat. 8124 Seeshaupt Roeder
Walter 8120 Weilheim Schneider
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE2612726A priority Critical patent/DE2612726C3/de
Priority to AT05477A priority patent/AT349651B/de
Priority to AR266169A priority patent/AR210632A1/es
Priority to IT19581/77A priority patent/IT1076016B/it
Priority to NLAANVRAGE7700686,A priority patent/NL188169C/xx
Priority to CA270,368A priority patent/CA1086615A/en
Priority to FI770294A priority patent/FI56536C/fi
Priority to SU772453752A priority patent/SU743600A3/ru
Priority to SE7703206A priority patent/SE428475B/xx
Priority to GB11994/77A priority patent/GB1517146A/en
Priority to FR7708519A priority patent/FR2345460A1/fr
Priority to CH369777A priority patent/CH629535A5/de
Priority to DD7700198026A priority patent/DD129692A5/xx
Priority to BR7701770A priority patent/BR7701770A/pt
Priority to AU23562/77A priority patent/AU509593B2/en
Priority to BE176043A priority patent/BE852791A/xx
Priority to JP52032754A priority patent/JPS6027516B2/ja
Priority to HU77BO1657A priority patent/HU179124B/hu
Priority to US05/781,222 priority patent/US4188465A/en
Publication of DE2612726A1 publication Critical patent/DE2612726A1/de
Publication of DE2612726B2 publication Critical patent/DE2612726B2/de
Application granted granted Critical
Publication of DE2612726C3 publication Critical patent/DE2612726C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/58—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving urea or urease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE2612726A 1976-03-25 1976-03-25 Stabilisierte Urease Expired DE2612726C3 (de)

Priority Applications (19)

Application Number Priority Date Filing Date Title
DE2612726A DE2612726C3 (de) 1976-03-25 1976-03-25 Stabilisierte Urease
AT05477A AT349651B (de) 1976-03-25 1977-01-07 Stabilisiertes ureasepraeparat
AR266169A AR210632A1 (es) 1976-03-25 1977-01-12 Ureasa estabilizada y reactivo que la contiene
IT19581/77A IT1076016B (it) 1976-03-25 1977-01-24 Ureasi stabilizzata
NLAANVRAGE7700686,A NL188169C (nl) 1976-03-25 1977-01-24 Werkwijze ter bereiding van gestabiliseerde urease, werkwijze ter bereiding of vervaardiging van een reagens voor het aantonen van ureum, alsmede proefpapier of -film.
CA270,368A CA1086615A (en) 1976-03-25 1977-01-24 Stabilised urease
FI770294A FI56536C (fi) 1976-03-25 1977-01-28 Mot aktivitetsfoerlust stabiliserat ureaspreparat
SU772453752A SU743600A3 (ru) 1976-03-25 1977-02-15 Стабилизированный состав дл определени мочевины, содержащий уреазу
SE7703206A SE428475B (sv) 1976-03-25 1977-03-21 Stabiliserad ureas
FR7708519A FR2345460A1 (fr) 1976-03-25 1977-03-22 Urease stabilisee
GB11994/77A GB1517146A (en) 1976-03-25 1977-03-22 Stabilised urease
DD7700198026A DD129692A5 (de) 1976-03-25 1977-03-23 Stabilisierte urease
BR7701770A BR7701770A (pt) 1976-03-25 1977-03-23 Urease estabilizada e reagente para a determinacao de ureia
AU23562/77A AU509593B2 (en) 1976-03-25 1977-03-23 Stabilised urease
BE176043A BE852791A (fr) 1976-03-25 1977-03-23 Urease stabilisee
CH369777A CH629535A5 (de) 1976-03-25 1977-03-23 Stabilisierte urease.
JP52032754A JPS6027516B2 (ja) 1976-03-25 1977-03-24 安定化ウレア−ゼ
HU77BO1657A HU179124B (en) 1976-03-25 1977-03-24 Stabilized urethane compositionand reagent for detecting urea
US05/781,222 US4188465A (en) 1976-03-25 1977-03-25 Stabilized urease composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2612726A DE2612726C3 (de) 1976-03-25 1976-03-25 Stabilisierte Urease

Publications (3)

Publication Number Publication Date
DE2612726A1 DE2612726A1 (de) 1977-10-06
DE2612726B2 DE2612726B2 (de) 1978-07-06
DE2612726C3 true DE2612726C3 (de) 1979-03-15

Family

ID=5973424

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2612726A Expired DE2612726C3 (de) 1976-03-25 1976-03-25 Stabilisierte Urease

Country Status (19)

Country Link
US (1) US4188465A (https=)
JP (1) JPS6027516B2 (https=)
AR (1) AR210632A1 (https=)
AT (1) AT349651B (https=)
AU (1) AU509593B2 (https=)
BE (1) BE852791A (https=)
BR (1) BR7701770A (https=)
CA (1) CA1086615A (https=)
CH (1) CH629535A5 (https=)
DD (1) DD129692A5 (https=)
DE (1) DE2612726C3 (https=)
FI (1) FI56536C (https=)
FR (1) FR2345460A1 (https=)
GB (1) GB1517146A (https=)
HU (1) HU179124B (https=)
IT (1) IT1076016B (https=)
NL (1) NL188169C (https=)
SE (1) SE428475B (https=)
SU (1) SU743600A3 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009057050A1 (de) * 2009-12-04 2011-06-09 Torsten Beel Urin-Indikator-Mittel

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4378430A (en) * 1979-09-11 1983-03-29 Modrovich Ivan Endre Method of forming stabilized urease solutions
US4282316A (en) * 1979-09-11 1981-08-04 Modrovich Ivan Endre Stabilized enzymic solutions for determining urea
US4465770A (en) * 1979-09-11 1984-08-14 Modrovich Ivan Endre Stabilized enzymic solutions for determining urea
US4350659A (en) * 1981-07-30 1982-09-21 Corning Glass Works Stabilization of sensitive biologically active intermediate metabolites such as folic acid derivatives
JPS62502653A (ja) * 1985-02-11 1987-10-15 トラベノ−ル‐ジエネンテツク、ダイアグノスチクス 安定化された酵素基質溶液
AU2003296492A1 (en) * 2002-12-11 2004-06-30 Instrumentation Laboratory Company Multi-analyte reference solutions
US20040154933A1 (en) * 2003-02-11 2004-08-12 Instrumentation Laboratory Company Polymeric membranes for use in electrochemical sensors
US20040256227A1 (en) * 2003-02-11 2004-12-23 Jungwon Shin Electrochemical urea sensors and methods of making the same
US20050176650A1 (en) * 2004-02-09 2005-08-11 Xanodyne Pharmacal, Inc. Stable parenteral formulation of levomepromazine and a method for stabilizing said formulation
BRPI0718328A2 (pt) 2006-12-15 2011-10-11 Lifebond Ltd composição, curativo hemostático e dispositivo médico para a inserção em um corpo de um ser humano ou de um mamìfero inferior
WO2009153748A2 (en) * 2008-06-18 2009-12-23 Lifebond Ltd Methods and devices for use with sealants
EP2543394A1 (en) * 2008-06-18 2013-01-09 Lifebond Ltd A method for enzymatic cross-linking of a protein
EP2487206A3 (en) * 2008-06-18 2012-11-28 Lifebond Ltd Cross-linkable gelatin-based compositions
WO2011077388A1 (en) 2009-12-22 2011-06-30 Lifebond Ltd Modification of enzymatic crosslinkers for controlling properties of crosslinked matrices
US8961544B2 (en) 2010-08-05 2015-02-24 Lifebond Ltd. Dry composition wound dressings and adhesives comprising gelatin and transglutaminase in a cross-linked matrix
SI2606147T1 (sl) 2010-08-20 2015-02-27 Cytonet Gmbh & Co. Kg Postopek za izoliranje uree z eliminiranjem moteäśega co2
US11998654B2 (en) 2018-07-12 2024-06-04 Bard Shannon Limited Securing implants and medical devices
AU2024312148A1 (en) * 2023-06-20 2025-11-27 Awak Technologies Pte Ltd Immobilised urease formulations with improved shelf life

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1321659A (fr) * 1961-03-20 1963-03-22 Albert L Chaney Chemical Lab Méthode de dosage de l'azote dans les fluides biologiques
USRE26125E (en) * 1962-05-08 1966-12-13 Reagents and analysis of nitrogen
US3527674A (en) * 1966-06-30 1970-09-08 Calbiochem Reagent material and method for urea assay
US3542649A (en) * 1967-04-07 1970-11-24 Hoffmann La Roche Color developing composition consisting of an enzyme,a salicylate and a hypochlorite donor
DE1758581C3 (de) * 1968-06-29 1974-01-10 Demag Ag, 4100 Duisburg Stützvorrichtung für ein metallurgisches Gefäß, insbesondere für einen Stahlwerkskonverter
ZA733611B (en) * 1972-10-11 1974-04-24 Merck Patent Gmbh Indicator for the determination of urea
DE2329174C2 (de) * 1973-06-07 1975-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur quantitativen Bestimmung von Blutammoniak

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009057050A1 (de) * 2009-12-04 2011-06-09 Torsten Beel Urin-Indikator-Mittel

Also Published As

Publication number Publication date
HU179124B (en) 1982-08-28
SE7703206L (sv) 1977-09-26
DE2612726A1 (de) 1977-10-06
SU743600A3 (ru) 1980-06-25
BE852791A (fr) 1977-09-23
CA1086615A (en) 1980-09-30
FR2345460A1 (fr) 1977-10-21
IT1076016B (it) 1985-04-22
FI770294A7 (https=) 1977-09-26
JPS6027516B2 (ja) 1985-06-29
NL188169B (nl) 1991-11-18
AU2356277A (en) 1978-09-28
FR2345460B1 (https=) 1982-12-17
NL188169C (nl) 1992-04-16
US4188465A (en) 1980-02-12
SE428475B (sv) 1983-07-04
AT349651B (de) 1979-04-25
DD129692A5 (de) 1978-02-01
NL7700686A (nl) 1977-09-27
BR7701770A (pt) 1978-01-17
CH629535A5 (de) 1982-04-30
JPS52117488A (en) 1977-10-01
GB1517146A (en) 1978-07-12
DE2612726B2 (de) 1978-07-06
FI56536B (fi) 1979-10-31
FI56536C (fi) 1980-02-11
AU509593B2 (en) 1980-05-15
ATA5477A (de) 1978-09-15
AR210632A1 (es) 1977-08-31

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
EI Miscellaneous see part 3