DE2505519A1 - Prostaglandinanaloge, verfahren zu ihrer herstellung und diese enthaltende arzneimittel - Google Patents

Prostaglandinanaloge, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Info

Publication number
DE2505519A1
DE2505519A1 DE19752505519 DE2505519A DE2505519A1 DE 2505519 A1 DE2505519 A1 DE 2505519A1 DE 19752505519 DE19752505519 DE 19752505519 DE 2505519 A DE2505519 A DE 2505519A DE 2505519 A1 DE2505519 A1 DE 2505519A1
Authority
DE
Germany
Prior art keywords
radical
hydroxy
methyl
radicals
prostaglandin analogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752505519
Other languages
German (de)
English (en)
Inventor
Masaki Hayashi
Seiji Kori
Hajimu Miyake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of DE2505519A1 publication Critical patent/DE2505519A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE19752505519 1974-02-13 1975-02-10 Prostaglandinanaloge, verfahren zu ihrer herstellung und diese enthaltende arzneimittel Withdrawn DE2505519A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB6610/74A GB1488006A (en) 1974-02-13 1974-02-13 Prostaglandin analogues

Publications (1)

Publication Number Publication Date
DE2505519A1 true DE2505519A1 (de) 1975-08-14

Family

ID=9817609

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752505519 Withdrawn DE2505519A1 (de) 1974-02-13 1975-02-10 Prostaglandinanaloge, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Country Status (13)

Country Link
US (1) US4140712A (en:Method)
JP (1) JPS50111050A (en:Method)
AU (1) AU7810075A (en:Method)
BE (1) BE825459A (en:Method)
DE (1) DE2505519A1 (en:Method)
DK (1) DK50775A (en:Method)
FI (1) FI750371A7 (en:Method)
FR (1) FR2260335B1 (en:Method)
GB (1) GB1488006A (en:Method)
LU (1) LU71831A1 (en:Method)
NL (1) NL7501613A (en:Method)
SE (1) SE7501512L (en:Method)
ZA (1) ZA75856B (en:Method)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054595A (en) * 1974-03-26 1977-10-18 Gist-Brocades N.V. 18 OR 19 Hydroxy prostaglandins
USRE30287E (en) * 1974-03-26 1980-05-27 Gist-Brocades N.V. 19 Hydroxy prostaglandins
US4267352A (en) * 1979-07-05 1981-05-12 The Upjohn Company 19-Hydroxy-19-methyl-6-oxo-PGF1 sulfonylamides
US4267371A (en) * 1979-07-05 1981-05-12 The Upjohn Company 19-Hydroxy-6a-carba-PGI2 amides
US4281191A (en) * 1979-04-02 1981-07-28 The Upjohn Company 19-Hydroxy-19-methyl-PG amides
US4281150A (en) * 1979-07-05 1981-07-28 The Upjohn Company 19-Hydroxy-19-methyl-6a-carba-PGI2 sulfonylamides
US4289904A (en) * 1979-07-05 1981-09-15 The Upjohn Company 19-Hydroxy-6a-carba-PGI2 sulfonylamides
US4312997A (en) * 1979-07-05 1982-01-26 The Upjohn Company 19-Hydroxy-6-oxo-PGF1 amides

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK142235B (da) * 1974-12-20 1980-09-29 Yamanouchi Pharma Co Ltd Analogifremgangsmåde til fremstilling af 20-alkoxy-16-methyl-prostadiensyre-derivater.
US4259513A (en) * 1979-04-02 1981-03-31 The Upjohn Company 19-Hydroxy-13,14-dihydro-PG1 compounds
JPS58121243A (ja) * 1982-01-12 1983-07-19 Sumitomo Chem Co Ltd 新規ビシクロオクタン誘導体及びその製造法
DE4014665C2 (de) * 1990-05-08 1994-06-01 Sanol Arznei Schwarz Gmbh Oberflächenvergütete Gläser in Primärpackmitteln von Lyophilisaten und deren Verwendung bei der Herstellung von Lyophilisaten
SE9900025D0 (sv) 1999-01-08 1999-01-08 Synphora Ab Method and composition for treatment of female sexual dysfunction

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3843713A (en) * 1972-04-05 1974-10-22 Ciba Geigy Corp 16-lower alkoxy lower alkyl,-16-20 w-pentano,pge
JPS5432773B2 (en:Method) * 1972-05-09 1979-10-16
JPS50116453A (en:Method) * 1974-02-28 1975-09-11

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054595A (en) * 1974-03-26 1977-10-18 Gist-Brocades N.V. 18 OR 19 Hydroxy prostaglandins
USRE30287E (en) * 1974-03-26 1980-05-27 Gist-Brocades N.V. 19 Hydroxy prostaglandins
US4281191A (en) * 1979-04-02 1981-07-28 The Upjohn Company 19-Hydroxy-19-methyl-PG amides
US4267352A (en) * 1979-07-05 1981-05-12 The Upjohn Company 19-Hydroxy-19-methyl-6-oxo-PGF1 sulfonylamides
US4267371A (en) * 1979-07-05 1981-05-12 The Upjohn Company 19-Hydroxy-6a-carba-PGI2 amides
US4281150A (en) * 1979-07-05 1981-07-28 The Upjohn Company 19-Hydroxy-19-methyl-6a-carba-PGI2 sulfonylamides
US4289904A (en) * 1979-07-05 1981-09-15 The Upjohn Company 19-Hydroxy-6a-carba-PGI2 sulfonylamides
US4312997A (en) * 1979-07-05 1982-01-26 The Upjohn Company 19-Hydroxy-6-oxo-PGF1 amides

Also Published As

Publication number Publication date
FR2260335B1 (en:Method) 1978-07-21
US4140712A (en) 1979-02-20
LU71831A1 (en:Method) 1975-12-09
NL7501613A (nl) 1975-08-15
ZA75856B (en) 1976-01-28
AU7810075A (en) 1976-08-12
FR2260335A1 (en:Method) 1975-09-05
GB1488006A (en) 1977-10-05
BE825459A (fr) 1975-08-12
DK50775A (en:Method) 1975-10-06
JPS50111050A (en:Method) 1975-09-01
SE7501512L (en:Method) 1975-08-14
FI750371A7 (en:Method) 1975-08-14

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination