DE248777A - - Google Patents
Info
- Publication number
- DE248777A DE248777A DE248777A DE 248777 A DE248777 A DE 248777A DE 248777 A DE248777 A DE 248777A
- Authority
- DE
- Germany
- Prior art keywords
- acid
- phenyl
- acids
- derivatives
- ether
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002253 acid Substances 0.000 claims description 8
- 150000001408 amides Chemical class 0.000 claims description 6
- 150000007513 acids Chemical class 0.000 claims description 5
- SHDBWXXRCCHGQD-UHFFFAOYSA-N 2-methyl-2-(4-methylphenyl)propanoic acid Chemical compound CC1=CC=C(C(C)(C)C(O)=O)C=C1 SHDBWXXRCCHGQD-UHFFFAOYSA-N 0.000 claims description 2
- 125000000217 alkyl group Chemical group 0.000 claims description 2
- 125000003118 aryl group Chemical group 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 10
- -1 phenyl diethylacetylurea Chemical compound 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- PYXQBGGQMBEYLO-UHFFFAOYSA-N 2-ethyl-2-phenylbutanoic acid Chemical compound CCC(CC)(C(O)=O)C1=CC=CC=C1 PYXQBGGQMBEYLO-UHFFFAOYSA-N 0.000 description 2
- VZFHOKANOVYGHO-UHFFFAOYSA-N 2-phenyl-2-propylpentanenitrile Chemical compound CCCC(CCC)(C#N)C1=CC=CC=C1 VZFHOKANOVYGHO-UHFFFAOYSA-N 0.000 description 2
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 239000004471 Glycine Substances 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- 230000000147 hypnotic effect Effects 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 150000002825 nitriles Chemical class 0.000 description 2
- 239000003208 petroleum Substances 0.000 description 2
- QHQWYLVUSIWEDA-UHFFFAOYSA-N 2-(2-phenylethyl)pentanoic acid Chemical compound CCCC(C(O)=O)CCC1=CC=CC=C1 QHQWYLVUSIWEDA-UHFFFAOYSA-N 0.000 description 1
- VMWAPTXFNZLIEZ-UHFFFAOYSA-N 2-ethyl-2-phenylbutanoyl chloride Chemical compound CCC(CC)(C(Cl)=O)C1=CC=CC=C1 VMWAPTXFNZLIEZ-UHFFFAOYSA-N 0.000 description 1
- ABNUAFDYCOJGOZ-UHFFFAOYSA-N 2-methyl-2-(4-methylphenyl)propanamide Chemical compound CC1=CC=C(C(C)(C)C(N)=O)C=C1 ABNUAFDYCOJGOZ-UHFFFAOYSA-N 0.000 description 1
- RINQAFSDAWYOFT-UHFFFAOYSA-N 2-phenyl-2-propylpentanoic acid Chemical compound CCCC(CCC)(C(O)=O)C1=CC=CC=C1 RINQAFSDAWYOFT-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 150000001805 chlorine compounds Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 125000001033 ether group Chemical group 0.000 description 1
- OHZZTXYKLXZFSZ-UHFFFAOYSA-I manganese(3+) 5,10,15-tris(1-methylpyridin-1-ium-4-yl)-20-(1-methylpyridin-4-ylidene)porphyrin-22-ide pentachloride Chemical compound [Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Mn+3].C1=CN(C)C=CC1=C1C(C=C2)=NC2=C(C=2C=C[N+](C)=CC=2)C([N-]2)=CC=C2C(C=2C=C[N+](C)=CC=2)=C(C=C2)N=C2C(C=2C=C[N+](C)=CC=2)=C2N=C1C=C2 OHZZTXYKLXZFSZ-UHFFFAOYSA-I 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- SUSQOBVLVYHIEX-UHFFFAOYSA-N phenylacetonitrile Chemical compound N#CCC1=CC=CC=C1 SUSQOBVLVYHIEX-UHFFFAOYSA-N 0.000 description 1
- 230000006207 propylation Effects 0.000 description 1
- 238000007127 saponification reaction Methods 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 150000003672 ureas Chemical class 0.000 description 1
Family
ID=
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