DE2463001C2 - - Google Patents

Info

Publication number
DE2463001C2
DE2463001C2 DE2463001A DE2463001A DE2463001C2 DE 2463001 C2 DE2463001 C2 DE 2463001C2 DE 2463001 A DE2463001 A DE 2463001A DE 2463001 A DE2463001 A DE 2463001A DE 2463001 C2 DE2463001 C2 DE 2463001C2
Authority
DE
Germany
Prior art keywords
methyl
esters
acid
chlorobenzyl
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2463001A
Other languages
German (de)
English (en)
Inventor
Kurt Dr. Zofingen Ch Thiele
Quazi Dr. Strengelbach Ch Ahmed
Andre Dr. Demolis
Georg Dr. Zofingen Ch Mixich
Rudolf Dr. Vordemwald Ch Adrian
Ulrich Dr. Zofingen De Jahn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siegfried AG
Original Assignee
Siegfried AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1814473A external-priority patent/CH605557A5/de
Priority claimed from CH1814573A external-priority patent/CH601169A5/de
Priority claimed from CH435574A external-priority patent/CH605642A5/de
Priority claimed from CH1330274A external-priority patent/CH616909A5/de
Priority claimed from CH1532974A external-priority patent/CH617417A5/de
Priority claimed from CH1533074A external-priority patent/CH617420A5/de
Application filed by Siegfried AG filed Critical Siegfried AG
Application granted granted Critical
Publication of DE2463001C2 publication Critical patent/DE2463001C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
  • Testing Resistance To Weather, Investigating Materials By Mechanical Methods (AREA)
DE2463001A 1973-12-27 1974-12-23 Expired DE2463001C2 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH1814473A CH605557A5 (en) 1973-12-27 1973-12-27 Phenoxy- and phenylthio-alkanes
CH1814573A CH601169A5 (en) 1973-12-27 1973-12-27 Phenoxy- and phenylthio-alkanes
CH435574A CH605642A5 (en) 1974-03-28 1974-03-28 Phenoxy- and phenylthio-alkanes
CH1330274A CH616909A5 (en) 1974-10-03 1974-10-03 Process for the preparation of aromatically substituted olefins
CH1532974A CH617417A5 (fr) 1973-12-27 1974-11-18
CH1533074A CH617420A5 (en) 1974-11-18 1974-11-18 Process for the preparation of novel pivaloyloxymethyl esters

Publications (1)

Publication Number Publication Date
DE2463001C2 true DE2463001C2 (fr) 1988-11-24

Family

ID=27543738

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2463001A Expired DE2463001C2 (fr) 1973-12-27 1974-12-23
DE2461069A Expired DE2461069C3 (de) 1973-12-27 1974-12-23 2-(4-Benzylphenoxy)-alkancarbonsäureester, Verfahren zu ihrer Herstellung und diese Ester enthaltende Arzneimittel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2461069A Expired DE2461069C3 (de) 1973-12-27 1974-12-23 2-(4-Benzylphenoxy)-alkancarbonsäureester, Verfahren zu ihrer Herstellung und diese Ester enthaltende Arzneimittel

Country Status (11)

Country Link
JP (1) JPS5934695B2 (fr)
BE (1) BE823904A (fr)
DE (2) DE2463001C2 (fr)
DK (1) DK157005C (fr)
FR (1) FR2255891B1 (fr)
GB (1) GB1497266A (fr)
IE (1) IE42425B1 (fr)
LU (1) LU71561A1 (fr)
NL (1) NL7416412A (fr)
SE (1) SE426582B (fr)
SU (1) SU612619A3 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211551A (en) * 1976-11-15 1980-07-08 Siegfried Ag Herbicide
US4214095A (en) * 1979-01-25 1980-07-22 Siegfried Aktiengesellschaft Chlorobenzyl phenoxy alkoxylates
FR2481702A1 (fr) * 1980-04-30 1981-11-06 Anvar Phenoxyacetates substitues d'amines cycliques, procede d'obtention, applications a titre de medicaments et compositions pharmaceutiques les contenant
DE3037391A1 (de) * 1980-10-03 1982-05-19 King Consult GmbH, 5000 Köln Ester von 7-hydroxyalkyl-1,3-dimethylxanthinen, verfahren zu ihrer herstellung und ihre verwendung als lipidsenkende mittel
ATE14584T1 (de) * 1981-03-11 1985-08-15 Merckle Kg Chem Pharm L Verfahren zur herstellung von phenoxyalkancarbonsaeureestern von hydroxyaethyltheophyllin.
JPS59172440A (ja) * 1983-03-23 1984-09-29 Nippon Tokushu Noyaku Seizo Kk 置換フエノキシプロピオン酸エステル及びその中間体、それらの製法並びに除草剤
JPH02502998A (ja) * 1988-01-22 1990-09-20 ハルコフスキ　ナウチノ‐イススレドバテルスキ　インスティテュト　エンドクリノロギイ　イ　ヒミイ　ゴルモノフ ｎ‐クロロフェノキシイソ酪酸ウンデシルエステルおよびそれを基剤とした高類脂血症の治療用医薬製剤
DE102011006425A1 (de) 2010-03-31 2011-10-06 Awd.Pharma Gmbh & Co. Kg Pharmazeutische Zubereitung und deren Verwendung

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1620024B2 (de) * 1965-07-30 1973-12-06 Merck & Co., Inc., Rahway, N.J. (V.St.A.) 3'-Pyridylmethyl-2-(4- chlorphenoxyy2-methylpropionat
DE2356655A1 (de) * 1972-11-16 1974-05-22 Funai Pharmaceutical Ind Ltd Substituierte phenoxy-alpha-methylpropionsaeure-derivate und verfahren zur herstellung derselben
DE2308826A1 (de) * 1973-02-22 1974-10-10 Merckle Kg Chem Pharm L Phenoxyalkancarbonsaeurederivate, verfahren zu ihrer herstellung und arzneimittel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB860303A (en) * 1958-06-20 1961-02-01 Ici Ltd Pharmaceutical compositions comprising ª‡-aryloxy-aliphatic carboxylic acids and/or ª
GB1064252A (en) * 1963-09-19 1967-04-05 Ici Ltd Amides and pharmaceutical compositions containing them
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
GB1140748A (en) * 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
DE2149070C3 (de) * 1971-10-01 1978-03-23 Boehringer Mannheim Gmbh, 6800 Mannheim Phenoxyalkylcarbonsäurederivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1620024B2 (de) * 1965-07-30 1973-12-06 Merck & Co., Inc., Rahway, N.J. (V.St.A.) 3'-Pyridylmethyl-2-(4- chlorphenoxyy2-methylpropionat
DE2356655A1 (de) * 1972-11-16 1974-05-22 Funai Pharmaceutical Ind Ltd Substituierte phenoxy-alpha-methylpropionsaeure-derivate und verfahren zur herstellung derselben
DE2308826A1 (de) * 1973-02-22 1974-10-10 Merckle Kg Chem Pharm L Phenoxyalkancarbonsaeurederivate, verfahren zu ihrer herstellung und arzneimittel

Also Published As

Publication number Publication date
AU7690274A (en) 1976-07-01
SE7416163L (fr) 1975-06-30
BE823904A (fr) 1975-06-27
SU612619A3 (ru) 1978-06-25
DE2461069B2 (de) 1980-10-02
DK157005B (da) 1989-10-30
DK670274A (fr) 1975-09-08
NL7416412A (nl) 1975-07-01
GB1497266A (en) 1978-01-05
JPS50105621A (fr) 1975-08-20
FR2255891B1 (fr) 1978-11-10
FR2255891A1 (fr) 1975-07-25
SE426582B (sv) 1983-01-31
IE42425B1 (en) 1980-08-13
DE2461069C3 (de) 1981-07-23
IE42425L (en) 1975-06-27
DK157005C (da) 1990-03-26
LU71561A1 (fr) 1975-08-20
JPS5934695B2 (ja) 1984-08-24
DE2461069A1 (de) 1975-07-17

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Legal Events

Date Code Title Description
OI Miscellaneous see part 1
OI Miscellaneous see part 1
8125 Change of the main classification

Ipc: C07D213/30

AC Divided out of

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D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee