DE2333883C3 - Verfahren zur Herstellung von hochgereinigtem Humanalbumin - Google Patents

Verfahren zur Herstellung von hochgereinigtem Humanalbumin

Info

Publication number
DE2333883C3
DE2333883C3 DE2333883A DE2333883A DE2333883C3 DE 2333883 C3 DE2333883 C3 DE 2333883C3 DE 2333883 A DE2333883 A DE 2333883A DE 2333883 A DE2333883 A DE 2333883A DE 2333883 C3 DE2333883 C3 DE 2333883C3
Authority
DE
Germany
Prior art keywords
albumin
solution
caprylate
concentration
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2333883A
Other languages
German (de)
English (en)
Other versions
DE2333883A1 (de
DE2333883B2 (de
Inventor
Paule Caluire Gattel
Jacques Limonest Liautaud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Merieux SA
Original Assignee
Institut Merieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Merieux SA filed Critical Institut Merieux SA
Publication of DE2333883A1 publication Critical patent/DE2333883A1/de
Publication of DE2333883B2 publication Critical patent/DE2333883B2/de
Application granted granted Critical
Publication of DE2333883C3 publication Critical patent/DE2333883C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y10S530/851—Placenta; amniotic fluid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE2333883A 1972-07-05 1973-07-03 Verfahren zur Herstellung von hochgereinigtem Humanalbumin Expired DE2333883C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7224311A FR2190437B1 (ja) 1972-07-05 1972-07-05

Publications (3)

Publication Number Publication Date
DE2333883A1 DE2333883A1 (de) 1974-01-31
DE2333883B2 DE2333883B2 (de) 1982-09-16
DE2333883C3 true DE2333883C3 (de) 1983-05-11

Family

ID=9101388

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2333883A Expired DE2333883C3 (de) 1972-07-05 1973-07-03 Verfahren zur Herstellung von hochgereinigtem Humanalbumin

Country Status (17)

Country Link
US (1) US3992367A (ja)
JP (1) JPS5312965B2 (ja)
AR (1) AR195041A1 (ja)
BE (1) BE801888A (ja)
BR (1) BR7305002D0 (ja)
CA (1) CA1028320A (ja)
DE (1) DE2333883C3 (ja)
DK (1) DK134425B (ja)
ES (1) ES416597A1 (ja)
FR (1) FR2190437B1 (ja)
GB (1) GB1441751A (ja)
LU (1) LU67931A1 (ja)
NL (1) NL179874C (ja)
NO (1) NO140579C (ja)
RO (1) RO64629A (ja)
SE (1) SE421997B (ja)
SU (1) SU591126A3 (ja)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2415079C3 (de) * 1974-03-28 1980-02-14 Plasmesco Ag, Zug (Schweiz) Verfahren zum Isolieren von Albumin aus Blutplasma
US4075197A (en) * 1976-09-20 1978-02-21 Monsanto Company Serum albumin production
DK25877A (da) * 1977-01-21 1978-08-15 Nordisk Insulinlab Fremgangsmaade til udvinding af renset albumin fra blodplasma
US4197238A (en) * 1977-04-12 1980-04-08 The Green Cross Corporation Method of preparation of human albumin using polyethylene glycol
US4164496A (en) * 1978-08-23 1979-08-14 American National Red Cross Preparation of albumin using PEG and EDTA
US4228154A (en) * 1979-02-26 1980-10-14 Armour Pharmaceutical Company Purification of plasma albumin by ion exchange chromatography
US4222934A (en) * 1979-04-12 1980-09-16 American National Red Cross Preparation of albumin using ethanol
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
DE3344656A1 (de) * 1983-12-09 1985-06-13 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Verfahren zur herstellung einer serumproteinloesung
JPS6152702U (ja) * 1984-09-12 1986-04-09
JPS62294621A (ja) * 1986-06-13 1987-12-22 Green Cross Corp:The アルブミンの回収方法
US4841023A (en) * 1986-06-25 1989-06-20 New York Blood Center, Inc. Inactivation of viruses in labile protein-containing compositions using fatty acids
US4791191A (en) * 1987-11-12 1988-12-13 Plasmatech Corporation Depyrogenation of clinical albumin
FR2632308B1 (fr) * 1988-06-07 1991-08-16 Fondation Nale Transfusion San Procede et installation de fractionnement en continu de proteines vegetales animales ou humaines
JPH0253505U (ja) * 1988-10-12 1990-04-18
US5277818A (en) * 1988-10-31 1994-01-11 The Green Cross Corporation Albumin preparation and process for preparing the same
FR2648048B1 (fr) * 1989-06-08 1994-06-03 Lille Transfusion Sanguine Procede de preparation de solutions d'albumine purifiee
JPH0671434B2 (ja) * 1989-09-18 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法
US5250663A (en) * 1990-04-19 1993-10-05 Miles Inc. Preparing essentially monomeric normal human serum albumin
US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5440018A (en) * 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
US5886154A (en) 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
US6955917B2 (en) * 1997-06-20 2005-10-18 Bayer Healthcare Llc Chromatographic method for high yield purification and viral inactivation of antibodies
GB9902000D0 (en) * 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
JP4935242B2 (ja) * 2006-08-24 2012-05-23 ニプロ株式会社 脂肪酸を含有するｓ−ニトロソタンパク質とその製法
WO2018165766A1 (en) 2017-03-16 2018-09-20 Therapure Biopharma Inc. Method for purification of albumin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2390074A (en) * 1942-02-09 1945-12-04 Research Corp Protein product and process
US2705230A (en) * 1949-09-23 1955-03-29 Allen F Reid Method of purifying albumin
US2770616A (en) * 1951-01-29 1956-11-13 Protein Foundation Inc Fractionation of proteinaceous materials in blood plasma and liver tissue
US2765299A (en) * 1952-06-27 1956-10-02 Armour & Co Recovery of serum albumin
US2761810A (en) * 1954-07-22 1956-09-04 Ortho Pharma Corp Preparation of blood fraction for use in rh testing procedures
US2958628A (en) * 1957-02-21 1960-11-01 Cutter Lab Heat treatable plasma protein product and method of preparation
US3100737A (en) * 1958-02-05 1963-08-13 Auerswald Wilhelm Method of preparing a plasma protein solution free of active hepatitis virus and product produced thereby
US3497492A (en) * 1968-04-02 1970-02-24 American Cyanamid Co Preparation of placental albumin
JPS5220524B1 (ja) * 1968-11-02 1977-06-04

Also Published As

Publication number Publication date
NL7309361A (ja) 1974-01-08
DK134425B (da) 1976-11-08
FR2190437B1 (ja) 1975-08-08
NL179874C (nl) 1986-12-01
RO64629A (fr) 1979-02-15
NL179874B (nl) 1986-07-01
FR2190437A1 (ja) 1974-02-01
DE2333883A1 (de) 1974-01-31
DK134425C (ja) 1977-04-12
BE801888A (fr) 1974-01-04
CA1028320A (en) 1978-03-21
JPS5312965B2 (ja) 1978-05-06
US3992367A (en) 1976-11-16
NO140579B (no) 1979-06-25
AR195041A1 (es) 1973-08-30
NO140579C (no) 1979-10-03
ES416597A1 (es) 1976-03-01
GB1441751A (en) 1976-07-07
BR7305002D0 (pt) 1974-08-15
DE2333883B2 (de) 1982-09-16
SU591126A3 (ru) 1978-01-30
LU67931A1 (ja) 1975-04-11
JPS4985219A (ja) 1974-08-15
SE421997B (sv) 1982-02-15

Similar Documents

Publication Publication Date Title
DE2333883C3 (de) Verfahren zur Herstellung von hochgereinigtem Humanalbumin
DE3412144C2 (ja)
DE2801123A1 (de) Verfahren zur herstellung eines intravenoes applizierbaren serumeiweiss- praeparates
DE3402647C2 (de) Verfahren zur Gewinnung von koloniestimulierendem Faktor und Kallikrein aus menschlichem Urin
DE3782768T2 (de) Verfahren fuer die produktion von im wesentlichen reinem albumin.
DE69133399T2 (de) Methode zur Herstellung von im Wesentlichen monomeren normalen menschlichen Serum-Albumin
DE3236126A1 (de) Verfahren zur herstellung von zur intravenoesen verabreichung geeignetem (gamma)-globulin
DE3101001A1 (de) Verfahren zur konzentration und reinigung des antihaemophilie-faktors oder faktor viii
DE2415079C3 (de) Verfahren zum Isolieren von Albumin aus Blutplasma
DE2333884C3 (de) Verfahren zum Herstellen von hochgereinigtem Humanalbumin
DE1517750B1 (de) Verfahren zur Gewinnung von praktisch albuminfreiem Lysozym
DE2733923C3 (de) Verfahren zur Gewinnung von Humanalbumin
DE3619565A1 (de) Verfahren zur herstellung einer pasteurisierten immunglobulinpraeparation
DE1642611C3 (de) Verfahren zur Beschleunigung der Kristallisation eines HühnereiweiB-Lysozymsalzes oder von isoelektrischem Hühnereiweiß-Lysozym
DE3307871C2 (de) Verfahren zur Gewinnung von hochreinem Albumin
AT259763B (de) Verfahren zur Herstellung einer pasteurisierten Plasmaproteinlösung
DE2154557A1 (de) Verfahren zur reinigung und kristallisation von kaudinogease (kallikrein)
DE1642592C (de) Verfahren zur Gewinnung von praktisch Fremdoxydase freier Glucose oxydase
DE876143C (de) Verfahren zur Gewinnung von Insulin aus insulinhaltigen Organen im Wege der Extraktion
DE2856939A1 (de) Verfahren zur gewinnung von intravenoes-vertraeglichen gammaglobulinen
DE1958386A1 (de) Verfahren zum Extrahieren von Pankreas
DE654960C (de) Verfahren zur Darstellung von wasserstoffuebertragenden Co-Enzymen
DE1517750C (de) Verfahren zur Gewinnung von praktisch albummfreiem Lysozym
AT271725B (de) Verfahren zur Gewinnung von Gammaglobulin
AT224807B (de) Verfahren zur Gewinnung eines neuen tumorhemmenden Polysaccharids

Legal Events

Date Code Title Description
OI Miscellaneous see part 1
AG Has addition no.

Ref country code: DE

Ref document number: 2333884

Format of ref document f/p: P

8128 New person/name/address of the agent

Representative=s name: BERENDT, T., DIPL.-CHEM. DR., PAT.-ANW., 8000 MUEN

AG Has addition no.

Ref country code: DE

Ref document number: 2333884

Format of ref document f/p: P

AG Has addition no.

Ref country code: DE

Ref document number: 2333884

Format of ref document f/p: P

C3 Grant after two publication steps (3rd publication)