DE2317538C2 - Carbonsäureamide, Verfahren zu deren Herstellung und deren Verwendung - Google Patents
Carbonsäureamide, Verfahren zu deren Herstellung und deren VerwendungInfo
- Publication number
- DE2317538C2 DE2317538C2 DE2317538A DE2317538A DE2317538C2 DE 2317538 C2 DE2317538 C2 DE 2317538C2 DE 2317538 A DE2317538 A DE 2317538A DE 2317538 A DE2317538 A DE 2317538A DE 2317538 C2 DE2317538 C2 DE 2317538C2
- Authority
- DE
- Germany
- Prior art keywords
- acid
- carboxamides
- iso
- carbon atoms
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003857 carboxamides Chemical class 0.000 title claims description 18
- 238000002360 preparation method Methods 0.000 title claims description 18
- 238000000034 method Methods 0.000 title claims description 3
- 125000004432 carbon atom Chemical group C* 0.000 claims description 11
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 10
- 150000001408 amides Chemical class 0.000 claims description 10
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 claims description 7
- 239000002826 coolant Substances 0.000 claims description 6
- 125000000217 alkyl group Chemical group 0.000 claims description 4
- 150000001412 amines Chemical class 0.000 claims description 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 38
- 239000000203 mixture Substances 0.000 description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 26
- 239000000243 solution Substances 0.000 description 24
- 230000000694 effects Effects 0.000 description 23
- 238000001816 cooling Methods 0.000 description 21
- 150000001875 compounds Chemical class 0.000 description 14
- 235000019504 cigarettes Nutrition 0.000 description 13
- 239000006210 lotion Substances 0.000 description 13
- 241000208125 Nicotiana Species 0.000 description 12
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 12
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 description 10
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 9
- 239000000344 soap Substances 0.000 description 9
- 239000007787 solid Substances 0.000 description 9
- 230000001476 alcoholic effect Effects 0.000 description 8
- 235000009508 confectionery Nutrition 0.000 description 7
- 239000002304 perfume Substances 0.000 description 7
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 6
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 6
- QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical compound CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 6
- 229940041616 menthol Drugs 0.000 description 6
- 239000002324 mouth wash Substances 0.000 description 6
- 239000003921 oil Substances 0.000 description 6
- 235000010585 Ammi visnaga Nutrition 0.000 description 5
- 244000153158 Ammi visnaga Species 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- 230000002421 anti-septic effect Effects 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 210000004400 mucous membrane Anatomy 0.000 description 5
- 230000035807 sensation Effects 0.000 description 5
- 235000019615 sensations Nutrition 0.000 description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- 229940069428 antacid Drugs 0.000 description 4
- 239000003159 antacid agent Substances 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 4
- 235000008504 concentrate Nutrition 0.000 description 4
- 239000012141 concentrate Substances 0.000 description 4
- 239000006071 cream Substances 0.000 description 4
- -1 fatty acid esters Chemical class 0.000 description 4
- 239000002674 ointment Substances 0.000 description 4
- 230000000391 smoking effect Effects 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000003826 tablet Substances 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 239000000443 aerosol Substances 0.000 description 3
- 230000001458 anti-acid effect Effects 0.000 description 3
- 238000009835 boiling Methods 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 229940112822 chewing gum Drugs 0.000 description 3
- 235000015218 chewing gum Nutrition 0.000 description 3
- 239000000551 dentifrice Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 239000004744 fabric Substances 0.000 description 3
- 229940051866 mouthwash Drugs 0.000 description 3
- 235000019520 non-alcoholic beverage Nutrition 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 239000002453 shampoo Substances 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical compound O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 description 2
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 2
- 206010000059 abdominal discomfort Diseases 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 235000013334 alcoholic beverage Nutrition 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 235000013361 beverage Nutrition 0.000 description 2
- 150000001721 carbon Chemical group 0.000 description 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 2
- 229940075894 denatured ethanol Drugs 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- FLKPEMZONWLCSK-UHFFFAOYSA-N diethyl phthalate Chemical compound CCOC(=O)C1=CC=CC=C1C(=O)OCC FLKPEMZONWLCSK-UHFFFAOYSA-N 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 229930195733 hydrocarbon Natural products 0.000 description 2
- 150000002430 hydrocarbons Chemical class 0.000 description 2
- 235000015243 ice cream Nutrition 0.000 description 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 2
- 235000015110 jellies Nutrition 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 2
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 2
- 239000001095 magnesium carbonate Substances 0.000 description 2
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 2
- 239000000155 melt Substances 0.000 description 2
- 239000007968 orange flavor Substances 0.000 description 2
- 239000003208 petroleum Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000003380 propellant Substances 0.000 description 2
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 2
- 229940081974 saccharin Drugs 0.000 description 2
- 235000019204 saccharin Nutrition 0.000 description 2
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 229960004793 sucrose Drugs 0.000 description 2
- 239000000454 talc Substances 0.000 description 2
- 229910052623 talc Inorganic materials 0.000 description 2
- 235000012222 talc Nutrition 0.000 description 2
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- ULJXKUJMXIVDOY-OPRDCNLKSA-N (1r,2r,5r)-2-methyl-5-propan-2-ylcyclohexan-1-ol Chemical compound CC(C)[C@@H]1CC[C@@H](C)[C@H](O)C1 ULJXKUJMXIVDOY-OPRDCNLKSA-N 0.000 description 1
- HLVFKOKELQSXIQ-UHFFFAOYSA-N 1-bromo-2-methylpropane Chemical compound CC(C)CBr HLVFKOKELQSXIQ-UHFFFAOYSA-N 0.000 description 1
- OWEMTCOXFULTNW-UHFFFAOYSA-N 2,3-dimethyl-2-propan-2-ylbutanoic acid Chemical compound CC(C)C(C)(C(C)C)C(O)=O OWEMTCOXFULTNW-UHFFFAOYSA-N 0.000 description 1
- WMEBPQLEDFWBRX-UHFFFAOYSA-N 2,3-dimethyl-2-propan-2-ylbutanoyl chloride Chemical compound CC(C)C(C)(C(C)C)C(Cl)=O WMEBPQLEDFWBRX-UHFFFAOYSA-N 0.000 description 1
- JPAMKBKLNCSGRD-UHFFFAOYSA-N 2,4-dimethyl-2-(2-methylpropyl)pentanoic acid Chemical compound CC(C)CC(C)(C(O)=O)CC(C)C JPAMKBKLNCSGRD-UHFFFAOYSA-N 0.000 description 1
- MIWKMBLORLMHOJ-UHFFFAOYSA-N 2-ethyl-3-methylbutanamide Chemical compound CCC(C(C)C)C(N)=O MIWKMBLORLMHOJ-UHFFFAOYSA-N 0.000 description 1
- PPPSEQGDDFQZNM-UHFFFAOYSA-N 2-ethyl-3-methylbutanoyl chloride Chemical compound CCC(C(C)C)C(Cl)=O PPPSEQGDDFQZNM-UHFFFAOYSA-N 0.000 description 1
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- ULJXKUJMXIVDOY-UHFFFAOYSA-N Carvomenthol Natural products CC(C)C1CCC(C)C(O)C1 ULJXKUJMXIVDOY-UHFFFAOYSA-N 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 206010013911 Dysgeusia Diseases 0.000 description 1
- 208000012895 Gastric disease Diseases 0.000 description 1
- 241000208680 Hamamelis mollis Species 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- 244000246386 Mentha pulegium Species 0.000 description 1
- 235000016257 Mentha pulegium Nutrition 0.000 description 1
- 235000004357 Mentha x piperita Nutrition 0.000 description 1
- 235000014443 Pyrus communis Nutrition 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000005844 Thymol Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 230000029936 alkylation Effects 0.000 description 1
- 238000005804 alkylation reaction Methods 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 229940024548 aluminum oxide Drugs 0.000 description 1
- 230000001166 anti-perspirative effect Effects 0.000 description 1
- 239000003831 antifriction material Substances 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 229940064004 antiseptic throat preparations Drugs 0.000 description 1
- UPURPFNAFBQPON-UHFFFAOYSA-N beta,beta-dimethyl valeric acid Chemical compound CCC(C)(C)CC(O)=O UPURPFNAFBQPON-UHFFFAOYSA-N 0.000 description 1
- 229910021538 borax Inorganic materials 0.000 description 1
- 239000001273 butane Substances 0.000 description 1
- 229960005069 calcium Drugs 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 235000019506 cigar Nutrition 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000035597 cooling sensation Effects 0.000 description 1
- 239000008278 cosmetic cream Substances 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- GXGAKHNRMVGRPK-UHFFFAOYSA-N dimagnesium;dioxido-bis[[oxido(oxo)silyl]oxy]silane Chemical compound [Mg+2].[Mg+2].[O-][Si](=O)O[Si]([O-])([O-])O[Si]([O-])=O GXGAKHNRMVGRPK-UHFFFAOYSA-N 0.000 description 1
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- NTNZTEQNFHNYBC-UHFFFAOYSA-N ethyl 2-aminoacetate Chemical compound CCOC(=O)CN NTNZTEQNFHNYBC-UHFFFAOYSA-N 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000003889 eye drop Substances 0.000 description 1
- 229940012356 eye drops Drugs 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 239000004088 foaming agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 150000008282 halocarbons Chemical class 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000008141 laxative Substances 0.000 description 1
- 229940125722 laxative agent Drugs 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 229940031958 magnesium carbonate hydroxide Drugs 0.000 description 1
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 1
- 239000000347 magnesium hydroxide Substances 0.000 description 1
- 229910001862 magnesium hydroxide Inorganic materials 0.000 description 1
- 229960000816 magnesium hydroxide Drugs 0.000 description 1
- 239000000395 magnesium oxide Substances 0.000 description 1
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 1
- 229960000869 magnesium oxide Drugs 0.000 description 1
- 239000000391 magnesium silicate Substances 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 229940099273 magnesium trisilicate Drugs 0.000 description 1
- 229910000386 magnesium trisilicate Inorganic materials 0.000 description 1
- 235000019793 magnesium trisilicate Nutrition 0.000 description 1
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- PCOMMNVANAQDMV-UHFFFAOYSA-N n,2-diethyl-3-methyl-2-propan-2-ylbutanamide Chemical compound CCNC(=O)C(CC)(C(C)C)C(C)C PCOMMNVANAQDMV-UHFFFAOYSA-N 0.000 description 1
- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 description 1
- MLGQKMLAQSNRSE-UHFFFAOYSA-N n-ethyl-2,3-dimethyl-2-propan-2-ylbutanamide Chemical compound CCNC(=O)C(C)(C(C)C)C(C)C MLGQKMLAQSNRSE-UHFFFAOYSA-N 0.000 description 1
- OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 239000000025 natural resin Substances 0.000 description 1
- 210000001640 nerve ending Anatomy 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 235000015205 orange juice Nutrition 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- BXNRKCXZILSQHE-UHFFFAOYSA-N propane-1,2,3-triol;sulfuric acid Chemical compound OS(O)(=O)=O.OCC(O)CO BXNRKCXZILSQHE-UHFFFAOYSA-N 0.000 description 1
- FVSKHRXBFJPNKK-UHFFFAOYSA-N propionitrile Chemical compound CCC#N FVSKHRXBFJPNKK-UHFFFAOYSA-N 0.000 description 1
- 239000003223 protective agent Substances 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 239000008257 shaving cream Substances 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 239000004328 sodium tetraborate Substances 0.000 description 1
- CYFHBEJDHKXKGH-UHFFFAOYSA-M sodium;hydrogen carbonate;propane-1,2,3-triol Chemical compound [Na+].OC([O-])=O.OCC(O)CO CYFHBEJDHKXKGH-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- LVLJBRFCYXMKCE-UHFFFAOYSA-N sulfo dodecanoate Chemical class CCCCCCCCCCCC(=O)OS(O)(=O)=O LVLJBRFCYXMKCE-UHFFFAOYSA-N 0.000 description 1
- 230000037072 sun protection Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 229960000790 thymol Drugs 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- KMZJRCPGGAQHGC-UHFFFAOYSA-N trisodium boric acid borate Chemical compound [Na+].[Na+].[Na+].OB(O)O.[O-]B([O-])[O-] KMZJRCPGGAQHGC-UHFFFAOYSA-N 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 229940118846 witch hazel Drugs 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 229960001763 zinc sulfate Drugs 0.000 description 1
- 229910000368 zinc sulfate Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
- C12G3/06—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with flavouring ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/202—Aliphatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/205—Heterocyclic compounds
- A23L27/2054—Heterocyclic compounds having nitrogen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/32—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by acyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/24—Thermal properties
- A61K2800/244—Endothermic; Cooling; Cooling sensation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
- A61Q1/10—Preparations containing skin colorants, e.g. pigments for eyes, e.g. eyeliner, mascara
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q13/00—Formulations or additives for perfume preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/002—Aftershave preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q9/00—Preparations for removing hair or for aiding hair removal
- A61Q9/02—Shaving preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
- Fats And Perfumes (AREA)
- Manufacture Of Tobacco Products (AREA)
- Seasonings (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Confectionery (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1791472A GB1421743A (en) | 1972-04-18 | 1972-04-18 | Ingestible topical and other compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2317538A1 DE2317538A1 (de) | 1973-10-31 |
| DE2317538C2 true DE2317538C2 (de) | 1983-02-03 |
Family
ID=10103461
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2317538A Expired DE2317538C2 (de) | 1972-04-18 | 1973-04-07 | Carbonsäureamide, Verfahren zu deren Herstellung und deren Verwendung |
| DE2366423A Expired DE2366423C2 (de) | 1972-04-18 | 1973-04-07 | Verwendung von Carboxamiden als Kaltrezeptorstimulantien für Gegenstände oder Mittel mit einem Kühleffekt |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2366423A Expired DE2366423C2 (de) | 1972-04-18 | 1973-04-07 | Verwendung von Carboxamiden als Kaltrezeptorstimulantien für Gegenstände oder Mittel mit einem Kühleffekt |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US4230688A (https=) |
| JP (1) | JPS5935940B2 (https=) |
| AU (1) | AU468442B2 (https=) |
| BE (1) | BE798312A (https=) |
| BR (1) | BR7302825D0 (https=) |
| CA (1) | CA984745A (https=) |
| DE (2) | DE2317538C2 (https=) |
| FR (1) | FR2180942B1 (https=) |
| GB (1) | GB1421743A (https=) |
| HK (1) | HK43179A (https=) |
| NL (1) | NL181164C (https=) |
| ZA (1) | ZA732515B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3724900A1 (de) * | 1986-08-08 | 1988-03-10 | Colgate Palmolive Co | N-alkylneoalkanamide sowie diese enthaltenden zubereitungen |
Families Citing this family (248)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4193936A (en) * | 1971-02-04 | 1980-03-18 | Wilkinson Sword Limited | N-substituted paramenthane carboxamides |
| FR2452921A1 (fr) * | 1979-04-02 | 1980-10-31 | Rhone Poulenc Ind | Procede d'obtention de compositions parfumantes et de produits parfumes et compositions et produits ainsi obtenus |
| US4682982A (en) * | 1985-03-27 | 1987-07-28 | Colgate-Palmolive Company | Antistatic N-higher mono alkyl and mono alkenyl neoalkanamides, processes for manufacturing thereof, antistatic compositions containing such amides, and processes for decreasing accumulations of static charges on laundry |
| DE3783683T2 (de) * | 1986-01-31 | 1993-05-19 | Whitby Research Inc | Hautpenetration verbessernde zusammensetzungen. |
| US5182304A (en) * | 1986-08-08 | 1993-01-26 | Colgate-Palmolive Co. | N-lower alkyl neodecanamide insect repellents |
| US4804683A (en) * | 1986-08-08 | 1989-02-14 | Colgate-Palmolive Company | N-alkyl neotridecanamide insect repellents |
| US5258408A (en) * | 1986-08-08 | 1993-11-02 | Colgate-Palmolive Company | Process of repelling insects from an area by application of N-alkyl neoalkanamide insect repellent thereto |
| US5391578A (en) * | 1986-08-08 | 1995-02-21 | Colgate-Palmolive Co. | N-lower alkyl neoalkanamide insect repellents |
| US5434189A (en) * | 1986-08-08 | 1995-07-18 | Colgate-Palmolive Co. | N-alkyl neotridecanamide insect repellents |
| US5434190A (en) * | 1986-08-08 | 1995-07-18 | Colgate-Palmolive Co. | N-aryl and N-cycloalkyl neoalkanamide insect repellents |
| US4808414A (en) * | 1986-09-29 | 1989-02-28 | Nelson Research & Development Co. | Amide penetration enhancers for transdermal delivery of systemic agents |
| US4920101A (en) * | 1987-09-30 | 1990-04-24 | Nelson Research & Development Co. | Compositions comprising 1-oxo- or thiohydrocarbyl substituted azacycloaklkanes |
| US4879275A (en) * | 1987-09-30 | 1989-11-07 | Nelson Research & Development Co. | Penetration enhancers for transdermal delivery of systemic agent |
| US5143900A (en) * | 1989-05-19 | 1992-09-01 | Colgate-Palmolive Company | Perfumes containing N-lower alkyl neoalkanamide (s) |
| CA2054967C (en) * | 1990-11-06 | 1997-10-07 | Michael J. Greenberg | Enhanced flavors using menthone ketals |
| DE4110973A1 (de) * | 1991-04-05 | 1992-10-08 | Haarmann & Reimer Gmbh | Mittel mit physiologischem kuehleffekt und fuer diese mittel geeignete wirksame verbindungen |
| FI945411L (fi) * | 1992-05-18 | 1994-11-17 | Procter & Gamble | Viilentäviä koostumuksia |
| AU4530493A (en) * | 1992-06-17 | 1994-01-04 | Procter & Gamble Company, The | Coolant compositions with reduced stinging |
| WO1994008550A1 (en) * | 1992-10-09 | 1994-04-28 | The Procter & Gamble Company | Anaesthetic compositions |
| US5981591A (en) * | 1992-12-04 | 1999-11-09 | Mayor Pharmaceutical Laboratories, Inc. | Sprayable analgesic composition and method of use |
| US5760085A (en) * | 1993-04-30 | 1998-06-02 | The Procter & Gamble Company | Topical aromatic releasing compositions |
| ATE168265T1 (de) * | 1993-04-30 | 1998-08-15 | Procter & Gamble | Zusammensetzungen zur freigabe einer aromatischen substanz in die nase |
| JPH08509725A (ja) * | 1993-04-30 | 1996-10-15 | ザ、プロクター、エンド、ギャンブル、カンパニー | コートされた医薬組成物 |
| US5407665A (en) * | 1993-12-22 | 1995-04-18 | The Procter & Gamble Company | Ethanol substitutes |
| US5527530A (en) * | 1994-07-08 | 1996-06-18 | The Procter & Gamble Company | Alcoholic moisturizing after shave lotion |
| US5679324A (en) * | 1994-07-08 | 1997-10-21 | The Procter & Gamble Co. | Aerosol foamable fragrance composition |
| US5449512A (en) * | 1994-08-24 | 1995-09-12 | The Procter & Gamble Company | Anhydrous after shave lotions |
| US5856282A (en) * | 1994-12-22 | 1999-01-05 | The Procter & Gamble Company | Silicone compositions |
| EP0814751A1 (en) * | 1995-03-16 | 1998-01-07 | The Procter & Gamble Company | Coolant compositions |
| US6231900B1 (en) | 1995-08-19 | 2001-05-15 | The Procter & Gamble Company | Confectionery product and preparation thereof |
| EP0780127A1 (en) | 1995-12-19 | 1997-06-25 | The Procter & Gamble Company | A nasal spray containing a steroid and a antihistamine |
| US6767925B1 (en) | 1996-10-31 | 2004-07-27 | Joseph A. Deihl | Sprayable analgesic composition and method of use |
| DK0991371T3 (da) | 1997-01-16 | 2008-10-27 | Procter & Gamble | En metode til behandling af proteser |
| US20060029653A1 (en) * | 1997-01-29 | 2006-02-09 | Cronk Peter J | Therapeutic delivery system |
| WO1998040863A1 (en) * | 1997-03-14 | 1998-09-17 | Tv Interactive Data Corporation | A method of detachably attaching an insert to a remote control base and the resulting remote control |
| GB9707977D0 (en) | 1997-04-21 | 1997-06-11 | Procter & Gamble | Centre filled confectionery |
| GB9707978D0 (en) | 1997-04-21 | 1997-06-11 | Procter & Gamble | Throat soothing compositions |
| GB9707979D0 (en) | 1997-04-21 | 1997-06-11 | Procter & Gamble | Confectionery compositions |
| US6627233B1 (en) * | 1997-09-18 | 2003-09-30 | Wm. Wrigley Jr. Company | Chewing gum containing physiological cooling agents |
| DE69738913D1 (de) | 1997-09-18 | 2008-09-25 | Wrigley W M Jun Co | Kaugummi, enthaltend physiologisch kühlende wirkstoffe |
| US6455080B1 (en) | 1997-12-29 | 2002-09-24 | Wm. Wrigley Jr., Company | Chewing gum containing controlled release acyclic carboxamide and method of making |
| US7588793B1 (en) | 1998-06-05 | 2009-09-15 | Cadbury Adams Usa, Llc | Enhanced flavoring compositions containing N-ethyl-p-menthane-3-carboxamide and method of making and using same |
| US20010018579A1 (en) | 1998-12-18 | 2001-08-30 | Walter Klemp | Disposable absorbent garment having stretchable side waist regions |
| WO2000045815A1 (en) * | 1999-02-02 | 2000-08-10 | Avon Products, Inc. | Methods for alleviating discomfort of a hot flash and compositions therefor |
| US6323365B1 (en) * | 2000-07-28 | 2001-11-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Active derivative of valproic acid for the treatment of neurological and psychotic disorders and a method for their preparation |
| US8273367B2 (en) * | 2001-04-17 | 2012-09-25 | The Procter And Gamble Company | Articles comprising a mint odor-free cooling agent |
| WO2004011017A1 (en) * | 2002-07-31 | 2004-02-05 | Himalayan International Institute Of Yoga Science And Philosophy | Nasal irrigation solutions and methods of using same |
| WO2004023900A1 (en) * | 2002-09-10 | 2004-03-25 | Pepsico, Inc. | Use of surfactants to solubilize water-insoluble solids in beverages |
| AU2004226443A1 (en) * | 2003-03-26 | 2004-10-14 | Wm. Wrigley Jr. Company | Confectionery with fast flavor release jacket coating |
| ATE480211T1 (de) * | 2003-05-19 | 2010-09-15 | Procter & Gamble | Flüchtiges material enthaltender absobierender hygieneartikel mit sperrschichtverpackung |
| US8591974B2 (en) * | 2003-11-21 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for two or more active components as part of an edible composition |
| US8591972B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for coated active components as part of an edible composition |
| US20050112236A1 (en) | 2003-11-21 | 2005-05-26 | Navroz Boghani | Delivery system for active components as part of an edible composition having preselected tensile strength |
| US8591973B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for active components and a material having preselected hydrophobicity as part of an edible composition |
| US8389032B2 (en) | 2005-05-23 | 2013-03-05 | Kraft Foods Global Brands Llc | Delivery system for active components as part of an edible composition having selected particle size |
| US9271904B2 (en) | 2003-11-21 | 2016-03-01 | Intercontinental Great Brands Llc | Controlled release oral delivery systems |
| US8591968B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Edible composition including a delivery system for active components |
| US8597703B2 (en) | 2005-05-23 | 2013-12-03 | Kraft Foods Global Brands Llc | Delivery system for active components as part of an edible composition including a ratio of encapsulating material and active component |
| US20050137166A1 (en) * | 2003-12-19 | 2005-06-23 | Alcon, Inc. | Use of cooling agents to relieve mild ocular irritation and enhance comfort |
| US20070248717A1 (en) * | 2004-02-26 | 2007-10-25 | Johnson Sonya S | Confections Containing a Blend of Physiological Cooling Agents |
| US7482378B2 (en) | 2004-05-28 | 2009-01-27 | Millenium Specialty Chemicals, Inc. | Physiological cooling compositions |
| BRPI0514283A (pt) * | 2004-08-11 | 2008-06-10 | Cadbury Adams Usa Llc | composições para aquecimento e sistemas de liberação para as mesmas |
| US7955630B2 (en) | 2004-09-30 | 2011-06-07 | Kraft Foods Global Brands Llc | Thermally stable, high tensile strength encapsulated actives |
| US7727565B2 (en) | 2004-08-25 | 2010-06-01 | Cadbury Adams Usa Llc | Liquid-filled chewing gum composition |
| US20070148284A1 (en) | 2004-08-25 | 2007-06-28 | Cadbury Adams Usa Llc. | Liquid-filled chewing gum |
| GB0425661D0 (en) * | 2004-11-23 | 2004-12-22 | Givaudan Sa | Organic compounds |
| NZ556202A (en) * | 2005-01-04 | 2010-03-26 | Teikoku Pharma Usa Inc | Cooling topical patch preparation |
| US9198448B2 (en) | 2005-02-07 | 2015-12-01 | Intercontinental Great Brands Llc | Stable tooth whitening gum with reactive ingredients |
| ATE432616T1 (de) * | 2005-02-18 | 2009-06-15 | Procter & Gamble | Gefüllte süsswaren |
| DE602005002728T2 (de) * | 2005-02-18 | 2008-07-24 | The Procter & Gamble Company, Cincinnati | Coffein enthaltendes Konfekt |
| US20060243298A1 (en) * | 2005-04-28 | 2006-11-02 | The Procter & Gamble Company | Dental floss compositions comprising menthol and carboxamides |
| US7851005B2 (en) | 2005-05-23 | 2010-12-14 | Cadbury Adams Usa Llc | Taste potentiator compositions and beverages containing same |
| US7851006B2 (en) | 2005-05-23 | 2010-12-14 | Cadbury Adams Usa Llc | Taste potentiator compositions and beverages containing same |
| CN101179943B (zh) | 2005-05-23 | 2013-06-26 | 卡夫食品环球品牌有限责任公司 | 填充液体的咀嚼型胶基糖组合物 |
| WO2006127282A2 (en) | 2005-05-23 | 2006-11-30 | Cadbury Adams Usa Llc | Center-filled chewing gum composition |
| AU2006251543C1 (en) | 2005-05-23 | 2014-03-13 | Intercontinental Great Brands Llc | Confectionery composition including an elastomeric component, a cooked saccharide component, and a modified release component |
| JP4982485B2 (ja) | 2005-05-23 | 2012-07-25 | クラフト・フーズ・グローバル・ブランズ・エルエルシー | 液体充填チューインガム組成物 |
| US7851000B2 (en) | 2005-05-23 | 2010-12-14 | Cadbury Adams Usa Llc | Taste potentiator compositions and edible confectionery and chewing gum products containing same |
| US20060280852A1 (en) * | 2005-05-27 | 2006-12-14 | Cadbury Adams Usa Llc. | Vanilla-flavored compositions and delivery systems therefor |
| EP1885197A2 (en) * | 2005-06-01 | 2008-02-13 | Cadbury Adams USA LLC | Interconnected confectionery products and method of making and marketing same |
| US20060275361A1 (en) * | 2005-06-03 | 2006-12-07 | Cadbury Adams Usa Llc. | Rapidly dissolving gelatin compositions and products made therefrom |
| CN101242807B (zh) | 2005-08-12 | 2014-12-10 | 洲际大品牌有限责任公司 | 口腔润湿组合物,包含该组合物的递送系统及其制造方法 |
| ATE501719T1 (de) * | 2005-08-12 | 2011-04-15 | Procter & Gamble | Methoden und zusammensetzungen zur beruhigung von mund- und nasenschleimhäuten |
| US8287928B2 (en) * | 2005-08-22 | 2012-10-16 | Kraft Foods Global Brands Llc | Degradable chewing gum |
| US8263143B2 (en) * | 2005-08-22 | 2012-09-11 | Kraft Foods Global Brands Llc | Degradable chewing gum |
| US8268371B2 (en) | 2005-08-22 | 2012-09-18 | Kraft Foods Global Brands Llc | Degradable chewing gum |
| US8282971B2 (en) | 2005-08-22 | 2012-10-09 | Kraft Foods Global Brands Llc | Degradable chewing gum |
| EP1919303B1 (en) | 2005-09-02 | 2011-04-20 | Givaudan Nederland Services B.V. | Improved flavour compositions |
| US20070221236A1 (en) * | 2005-10-05 | 2007-09-27 | Cadbury Adams Usa Llc. | Cooling compositions including menthyl esters |
| CA2623545C (en) * | 2005-10-05 | 2013-04-09 | Cadbury Adams Usa Llc | Cooling compositions |
| CA2614345C (en) * | 2005-10-24 | 2013-01-08 | Teikoku Pharma Usa, Inc. | Topical pain relief compositions of n,2,3-trimethyl-2-isopropylbutamide and methods for using the same |
| US7432413B2 (en) | 2005-12-16 | 2008-10-07 | The Procter And Gamble Company | Disposable absorbent article having side panels with structurally, functionally and visually different regions |
| AU2006330915B2 (en) * | 2005-12-23 | 2011-02-03 | Intercontinental Great Brands Llc | Compositions providing a sensation substantially similar to that provided by menthol |
| EP1973422B1 (en) * | 2005-12-23 | 2014-06-11 | Intercontinental Great Brands LLC | Compositions providing a heating sensation for oral or dermal delivery |
| CA2636061C (en) * | 2006-01-27 | 2015-06-02 | Cadbury Adams Usa Llc | Flavor-enhancing compositions, methods of manufacture, and methods of use |
| DK1996027T3 (da) * | 2006-02-20 | 2012-12-03 | Gumlink As | Harpiksindkapslet næringsmiddelsyre |
| US8491558B2 (en) | 2006-03-31 | 2013-07-23 | The Procter & Gamble Company | Absorbent article with impregnated sensation material for toilet training |
| US8057450B2 (en) | 2006-03-31 | 2011-11-15 | The Procter & Gamble Company | Absorbent article with sensation member |
| US8664467B2 (en) | 2006-03-31 | 2014-03-04 | The Procter & Gamble Company | Absorbent articles with feedback signal upon urination |
| CA2648460C (en) | 2006-04-05 | 2014-09-23 | Cadbury Adams Usa Llc | Calcium phosphate complex and salts in oral delivery systems |
| MX2008013507A (es) * | 2006-04-21 | 2008-10-28 | Cadbury Adams Usa Llc | Composiciones de recubrimiento, composiciones de confiteria y goma de mascar y metodos. |
| MX2008016375A (es) | 2006-06-28 | 2009-01-19 | Cadbury Adams Usa Llc | Un proceso para fabricar un sistema de distribucion para componentes activos como parte de una composicion comestible. |
| DE602006014601D1 (de) * | 2006-08-17 | 2010-07-08 | Gumlink As | Harzverkapselter intensivsüsstoff |
| AU2007289078A1 (en) | 2006-08-30 | 2008-03-06 | David William Smith | Method of imparting a mono-axial or multiaxial stiffness to extruded materials and products resulting therefrom |
| EP2079321B1 (en) * | 2006-09-27 | 2013-05-01 | Kraft Foods Global Brands LLC | Cooling confectioneries and beverages |
| US20080166449A1 (en) | 2006-11-29 | 2008-07-10 | Cadbury Adams Usa Llc | Confectionery compositions including an elastomeric component and a saccharide component |
| CA2851763A1 (en) | 2006-12-04 | 2008-06-12 | The Procter & Gamble Company | Absorbent articles comprising graphics |
| GB0703525D0 (en) * | 2007-02-23 | 2007-04-04 | Cadbury Schweppes Plc | Method of making sweetner compositions |
| GB0703524D0 (en) * | 2007-02-23 | 2007-04-04 | Cadbury Schweppes Plc | Improved sweetener compositions |
| US20080213440A1 (en) | 2007-03-01 | 2008-09-04 | Cadbury Adams Usa Llc | Non-Aldehyde Cinnamon Flavor and Delivery Systems Therefor |
| US20090017080A1 (en) * | 2007-03-15 | 2009-01-15 | Paul Robert Tanner | Personal care kit having skin care compositions with a readily perceptible difference |
| WO2008122286A1 (en) * | 2007-04-04 | 2008-10-16 | Gumlink A/S | Center-filled chewing gum product for dental care |
| GB0713297D0 (en) | 2007-07-10 | 2007-08-15 | Cadbury Schweppes Plc | Chocolate compositions having improved flavour characteristics |
| GB0715226D0 (en) * | 2007-08-01 | 2007-09-12 | Cadbury Schweppes Plc | Sweetener compositions |
| GB0720516D0 (en) * | 2007-10-18 | 2007-11-28 | Cadbury Schweppes Plc | Comestible products |
| WO2009061871A1 (en) * | 2007-11-09 | 2009-05-14 | The Hershey Company | Multi-layered fondant containing chewing gum |
| US20090130251A1 (en) * | 2007-11-20 | 2009-05-21 | Cadbury Adams Usa Llc | Dual coated confectionery product |
| MX2010005424A (es) * | 2007-11-29 | 2010-06-01 | Cadbury Adams Usa Llc | Proceso de recubrimiento particulado. |
| PL2219467T3 (pl) | 2007-11-29 | 2015-02-27 | Intercontinental Great Brands Llc | Guma do żucia z wieloma obszarami z substancjami czynnymi |
| US8134042B2 (en) | 2007-12-14 | 2012-03-13 | Kimberly-Clark Worldwide, Inc. | Wetness sensors |
| CN102014655B (zh) | 2008-02-27 | 2016-01-13 | 洲际大品牌有限责任公司 | 多区糖食 |
| WO2009154887A1 (en) | 2008-05-02 | 2009-12-23 | Cadbury Adams Usa Llc | Multilayered sugar free polyol confectionery and methods of making same |
| RU2517179C2 (ru) * | 2008-08-15 | 2014-05-27 | Дзе Проктер Энд Гэмбл Компани | Синтез производных циклогексана, используемых в потребительских товарах в качестве оказывающих сенсорное воздействие веществ |
| CN102123695A (zh) * | 2008-08-15 | 2011-07-13 | 宝洁公司 | 用于消费品中的薄荷酰胺溶液 |
| GB0817367D0 (en) | 2008-09-23 | 2008-10-29 | Cadbury Uk Ltd | Confectionery and methods of production thereof |
| GB0817366D0 (en) * | 2008-09-23 | 2008-10-29 | Cadbury Uk Ltd | Confectionery and methods of production thereof |
| GB0817370D0 (en) * | 2008-09-23 | 2008-10-29 | Cadbury Uk Ltd | Chewing gum and methods of production thereof |
| GB0817368D0 (en) * | 2008-09-23 | 2008-10-29 | Cadbury Uk Ltd | Confectionery and methods of production thereof |
| GB0817369D0 (en) * | 2008-09-23 | 2008-10-29 | Cadbury Uk Ltd | Confectionery and methods of production thereof |
| WO2010056697A1 (en) * | 2008-11-12 | 2010-05-20 | Cadbury Adams Usa Llc | Sensate- plated sanding composition and products made therefrom |
| AU2009318056B2 (en) | 2008-11-20 | 2014-07-24 | The Procter & Gamble Company | Personal care compositions providing enhanced cooling sensation |
| MX336895B (es) * | 2008-11-28 | 2016-02-05 | Intercontinental Great Brands Llc | Composicion de confitura de goma de mascar de regiones multiples, articulo, metodo y aparato. |
| WO2010083133A1 (en) * | 2009-01-15 | 2010-07-22 | Cadbury Adams Usa Llc | Compositions and methods for the treatment of throat discomfort |
| CN104431264A (zh) | 2009-01-22 | 2015-03-25 | 洲际大品牌有限责任公司 | 糖食加工 |
| WO2011012421A1 (en) | 2009-07-29 | 2011-02-03 | Unilever Nv | A dentifrice composition comprising polyethyleneglycol and a cooling agent |
| BR112012002152A2 (pt) | 2009-07-30 | 2016-06-07 | Procter & Gamble | artigo de tratamento bucal |
| US8920856B2 (en) | 2009-10-08 | 2014-12-30 | Intercontinental Great Brands Llc | Co-extruded layered candy and gum apparatus and methods |
| PL2316279T3 (pl) | 2009-10-30 | 2014-03-31 | Intercontinental Great Brands Llc | Bezcukrowy wyrób cukierniczy, sposoby jego wytwarzania oraz zastosowanie do wytwarzania wielowarstwowych wyrobów cukierniczych |
| PL2515669T3 (pl) | 2009-12-21 | 2019-01-31 | Intercontinental Great Brands Llc | Rozdrobnione kompozycje powłokowe, powleczony wyrób cukierniczy oraz sposoby ich wytwarzania |
| CN103002750B (zh) | 2010-01-21 | 2015-10-07 | 洲际大品牌有限责任公司 | 形成咀嚼型胶基糖和确定咀嚼型胶基糖尺寸和/或改变咀嚼型胶基糖的温度的系统和方法 |
| GB201004890D0 (en) | 2010-03-23 | 2010-05-05 | Cadbury Uk Ltd | Confectionery product containing active and/or reactive components and methods of production thereof |
| GB201004899D0 (en) | 2010-03-23 | 2010-05-05 | Cadbury Uk Ltd | Confectionery products and methods for the formation thereof |
| MX343550B (es) | 2010-04-01 | 2016-11-08 | The Procter & Gamble Company * | Control del mal olor en toda la boca con una combinacion de agentes antibacterianos y desodorizantes. |
| WO2011139943A1 (en) | 2010-05-03 | 2011-11-10 | Kraft Foods Global Brands Llc | Natural chewing gum including cellulose materials |
| MX2012013889A (es) | 2010-06-02 | 2013-02-15 | Nihon Kraft Foods Ltd | Cofiteria de regiones multiples. |
| CN103228151A (zh) | 2010-06-25 | 2013-07-31 | 卡夫食品环球品牌有限责任公司 | 亲脂性成分从具有水胶体的咀嚼型胶基糖的增强的释放 |
| JP2013535450A (ja) | 2010-07-19 | 2013-09-12 | ザ プロクター アンド ギャンブル カンパニー | 精油化合物の誘導体を含む組成物、及びパーソナルケア製品における使用 |
| ES2543910T3 (es) | 2010-07-30 | 2015-08-25 | Intercontinental Great Brands Llc | Un sistema de suministro para componentes activos como parte de una composición comestible |
| CA2806959A1 (en) | 2010-08-18 | 2012-02-23 | Kraft Foods Global Brands Llc | Mouth-moistening gum compositions and products containing the same |
| JP2013534146A (ja) | 2010-08-18 | 2013-09-02 | クラフト・フーズ・グローバル・ブランズ・エルエルシー | 口内湿潤化ガム組成物およびそれを含む製品 |
| US20130216648A1 (en) | 2010-09-09 | 2013-08-22 | Kraft Foods Global Brands Llc | Chewing gum compositions providing flavor release profiles |
| CN103140209B (zh) | 2010-10-01 | 2017-10-13 | 宝洁公司 | 具有改善的风味的口腔护理组合物 |
| FR2968952A1 (fr) * | 2010-12-17 | 2012-06-22 | Oreal | Ester d'acide amine n-acyle a titre d'agent apaisant |
| EP2675283B1 (en) | 2011-02-14 | 2018-11-14 | Intercontinental Great Brands LLC | Confectionary with multiple flavors and textures |
| EP2677878B1 (en) | 2011-02-23 | 2016-02-17 | Intercontinental Great Brands LLC | Flavor pre-blends for chewing gum, methods of making flavor pre-blends and chewing gum compositions thereof |
| PL2683251T3 (pl) | 2011-03-11 | 2021-12-13 | Intercontinental Great Brands Llc | Sposób wytwarzania wielowarstwowych wyrobów cukierniczych |
| WO2012148432A1 (en) | 2011-04-28 | 2012-11-01 | Acme Specialty Products, Llc | Taste masking compositions and edible forms thereof |
| WO2012174091A2 (en) | 2011-06-13 | 2012-12-20 | The Procter & Gamble Company | PERSONAL CARE COMPOSITIONS COMPRISING A pH TUNEABLE GELLANT AND METHODS OF USING |
| JP2014524901A (ja) | 2011-06-13 | 2014-09-25 | ザ プロクター アンド ギャンブル カンパニー | ジアミドゲル化剤を含むパーソナルケア組成物及び使用方法 |
| WO2012177757A2 (en) | 2011-06-20 | 2012-12-27 | The Procter & Gamble Company | Personal care compositions comprising shaped abrasive particles |
| JP5912180B2 (ja) | 2011-07-21 | 2016-04-27 | インターコンチネンタル グレート ブランズ エルエルシー | チューインガムの形成および冷却のためのシステムおよび方法 |
| WO2013013041A2 (en) | 2011-07-21 | 2013-01-24 | Kraft Foods Global Brands Llc | Advanced gum forming |
| PL2734053T3 (pl) | 2011-07-21 | 2019-07-31 | Intercontinental Great Brands Llc | Zaawansowane formowanie gum do żucia |
| US20130042482A1 (en) | 2011-08-16 | 2013-02-21 | Valerie Jean Bradford | Skin Engaging Member Comprising An Anti-Irritation Agent |
| CN103930091B (zh) | 2011-09-01 | 2016-03-02 | 宝洁公司 | 具有改善的流变特性的口腔护理组合物 |
| US20150272161A1 (en) | 2011-12-21 | 2015-10-01 | Wm. Wrigley Jr. Company | Chewing gum products containing (r)-2-[((1r,2s,5r)-2-isopropyl-5-methylclohexanecarbonyl)-amino]-acetic acid isopropyl ester |
| JP2013195289A (ja) | 2012-03-21 | 2013-09-30 | Takasago Internatl Corp | 感覚刺激成分の評価方法 |
| JP6085364B2 (ja) | 2012-04-20 | 2017-02-22 | インターコンチネンタル グレート ブランズ エルエルシー | チューインガムを製造するシステムおよび方法 |
| RU2618043C2 (ru) * | 2012-04-30 | 2017-05-02 | Филип Моррис Продактс С.А. | Мундштук курительного изделия с комплексом включения холодящего агента |
| WO2013170433A1 (en) | 2012-05-15 | 2013-11-21 | The Procter & Gamble Company | Absorbent article having characteristic waist end |
| US20130315843A1 (en) | 2012-05-25 | 2013-11-28 | The Procter & Gamble Company | Composition for reduction of trpa1 and trpv1 sensations |
| US9271912B2 (en) | 2012-06-13 | 2016-03-01 | The Procter & Gamble Company | Personal care compositions comprising a pH tuneable gellant and methods of using |
| MX363748B (es) | 2012-06-19 | 2019-04-01 | Intercontinental Great Brands Llc | Goma de mascar sin recubrir, empacada a granel. |
| US10123953B2 (en) | 2012-06-21 | 2018-11-13 | The Procter & Gamble Company | Reduction of tooth staining derived from cationic antimicrobials |
| US20130344120A1 (en) | 2012-06-21 | 2013-12-26 | Douglas Craig Scott | Mouth Rinse Emulsions |
| BR112015003781A2 (pt) | 2012-08-22 | 2017-07-04 | Intercontinental Great Brands Llc | composições de goma de mascar e métodos para produzir as mesmas |
| JP6068643B2 (ja) | 2012-09-21 | 2017-01-25 | インターコンチネンタル グレート ブランズ エルエルシー | 改良型ガム形成 |
| AU2013323690B2 (en) | 2012-09-28 | 2016-09-22 | The Gillette Company Llc | A skin engaging member comprising at least one thermally resilient sensate |
| MX354139B (es) | 2012-09-28 | 2018-01-08 | Gillette Co Llc | Un miembro auxiliar de afeitado de acoplamiento con la piel que comprende al menos un agente percibido por los sentidos termicamente resilente. |
| WO2014128566A2 (en) | 2013-02-21 | 2014-08-28 | Mondelez International | Chewing gum and methods of making thereof field |
| CN105265704B (zh) | 2013-03-29 | 2019-03-22 | 洲际大品牌有限责任公司 | 不含食糖的液体可食组合物及其糖食产品或药物产品 |
| WO2014172287A1 (en) | 2013-04-17 | 2014-10-23 | Intercontinental Great Brands Llc | A system and method for forming a chewing gum product with at least one inclusion |
| WO2014194198A1 (en) | 2013-05-31 | 2014-12-04 | Intercontinental Great Brands Llc | Chewing gum with hard, amorphous inclusions; and methods of making thereof |
| WO2015051056A1 (en) | 2013-10-02 | 2015-04-09 | Intercontinental Great Brands Llc | Particulate coated chewing gum and confectionery; and methods of making the same |
| US9884130B2 (en) | 2013-11-13 | 2018-02-06 | The Procter & Gamble Company | Compositions for delivery of oral comfort sensations |
| KR20160096204A (ko) | 2013-12-23 | 2016-08-12 | 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 | 항비듬 모발 관리 조성물용 현탁 및 안정성 작용제 |
| CN106029175A (zh) | 2014-02-27 | 2016-10-12 | 宝洁公司 | 具有减少的苦味感受的口腔护理组合物 |
| EP3110259A2 (en) | 2014-02-28 | 2017-01-04 | Intercontinental Great Brands LLC | Coating for edible cores; system and process of coating; and coated products prepared therefrom |
| EP3131405A1 (en) | 2014-03-03 | 2017-02-22 | Intercontinental Great Brands LLC | Method for manufacturing a comestible |
| US20150273711A1 (en) | 2014-03-26 | 2015-10-01 | The Gillette Company | Razor Comprising A Molded Shaving Aid Composition Comprising A Thermally Resilient Sensate |
| US20150272847A1 (en) | 2014-03-26 | 2015-10-01 | The Gillette Company | Skin Engaging Shaving Aid Comprising A Thermally Resilient Sensate And A TRPA1 Receptor Inhibitor |
| JP2017518963A (ja) | 2014-04-23 | 2017-07-13 | ザ プロクター アンド ギャンブル カンパニー | 生体表面付着組成物 |
| EP3142494A1 (en) | 2014-05-15 | 2017-03-22 | Intercontinental Great Brands LLC | Multi-textured chewing gum and methods of making thereof |
| WO2015195534A2 (en) | 2014-06-16 | 2015-12-23 | Intercontinental Great Brands Llc | Degradable chewing gum |
| EP3180090A1 (en) | 2014-08-15 | 2017-06-21 | The Procter and Gamble Company | Oral care compositions and regimens |
| MX2017002100A (es) | 2014-08-15 | 2017-05-04 | Procter & Gamble | Dentifrico con sustancias quimicas incrementales. |
| CA2956964C (en) | 2014-08-15 | 2019-07-16 | The Procter & Gamble Company | Oral care compositions with an enhanced sensory experience |
| BR112017011022B1 (pt) | 2014-11-26 | 2021-02-17 | The Gillette Company Llc | dispositivo de remoção de pelo e processo de formação de um membro de engate à pele |
| BR112017012784A2 (pt) | 2014-12-18 | 2018-01-02 | Lubrizol Advanced Mat Inc | composição anticaspa, e, método para intensificar a estabilidade de fase de uma composição de xampu anticaspa. |
| WO2016105879A1 (en) | 2014-12-22 | 2016-06-30 | Intercontinental Great Brands Llc | Confectionery and multi-layer chewing gum confectionery composition and article |
| US9951295B2 (en) | 2015-02-19 | 2018-04-24 | The Procter & Gamble Company | Compositions for deposition on biological surfaces |
| WO2016138331A1 (en) | 2015-02-27 | 2016-09-01 | Kimberly-Clark Worldwide, Inc. | Absorbent article leakage assessment system |
| AR104220A1 (es) | 2015-04-09 | 2017-07-05 | Procter & Gamble | Reducción de la aversión al sabor del cpc mediante la reducción de la activación del cpc de los receptores de trpa1, receptores de trpv1, o ambos |
| US10173966B2 (en) | 2015-06-04 | 2019-01-08 | Symrise, Inc. | Physiological cooling compounds |
| JP2018533567A (ja) | 2015-10-22 | 2018-11-15 | ザ プロクター アンド ギャンブル カンパニー | クロマトグラフィー分離方法 |
| EP3365324A1 (en) | 2015-10-22 | 2018-08-29 | The Procter and Gamble Company | Synthesis of cyclohexane carboxamide derivatives useful as sensates in consumer products |
| CN108368035A (zh) | 2015-12-18 | 2018-08-03 | 宝洁公司 | 在消费品中可用作感觉剂的环己烷酯衍生物的合成 |
| KR20180098330A (ko) | 2015-12-23 | 2018-09-03 | 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 | 소수성 개질된 알칼리-팽윤성 에멀젼 폴리머 |
| AU2017240034B2 (en) | 2016-04-01 | 2020-02-06 | The Procter & Gamble Company | Oral care compositions containing a gel network phase |
| BR112018069874A2 (pt) | 2016-04-01 | 2019-02-05 | Procter & Gamble | composições para tratamento bucal contendo uma fase de rede de gel e nitrato de potássio |
| AU2017240683B2 (en) | 2016-04-01 | 2020-01-16 | The Procter & Gamble Company | Oral care compositions containing potassium nitrate and peroxide |
| EP3435957A1 (en) | 2016-04-01 | 2019-02-06 | The Procter and Gamble Company | Oral care compositions containing gel networks and potassium nitrate |
| CA3018559A1 (en) | 2016-04-01 | 2017-10-05 | The Procter & Gamble Company | Oral care compositions with an effective flavor display |
| US20170334082A1 (en) | 2016-05-18 | 2017-11-23 | The Gillette Company Llc | Skin Engaging Member Comprising Ethylene Vinyl Acetate |
| WO2018081189A1 (en) | 2016-10-25 | 2018-05-03 | The Procter & Gamble Company | Fibrous structures |
| WO2018081190A1 (en) | 2016-10-25 | 2018-05-03 | The Procter & Gamble Company | Fibrous structures |
| WO2018085479A1 (en) | 2016-11-03 | 2018-05-11 | The Gillette Company Llc | Skin engaging member comprising ethylene vinyl acetate |
| EP3541476A1 (en) | 2016-11-17 | 2019-09-25 | The Gillette Company LLC | Skin engaging member comprising ethylene vinyl acetate and a fragrance |
| KR102493173B1 (ko) | 2017-01-10 | 2023-01-27 | 다카사고 고료 고교 가부시키가이샤 | 메틸멘톨 유도체 및 그것을 함유하는 냉감제 조성물 |
| US11896028B2 (en) | 2017-02-06 | 2024-02-13 | Intercontinental Great Brands Llc | Dual-textured confectionery; and methods of making the same |
| WO2018186842A1 (en) | 2017-04-05 | 2018-10-11 | Kimberly-Clark Worldwide, Inc. | Garment for detecting absorbent article leakage and methods of detecting absorbent article leakage utilizing the same |
| PT3850950T (pt) | 2017-06-05 | 2024-01-12 | Perfetti Van Melle Benelux B V | Composições de goma de mascar e métodos para a fabricação das mesmas |
| PT3668326T (pt) | 2017-08-18 | 2024-01-09 | Perfetti Van Melle Benelux B V | Composições de goma de mascar e métodos para fabricação das mesmas |
| SG11202003286YA (en) | 2017-10-16 | 2020-05-28 | Takasago Perfumery Co Ltd | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative |
| CN112312915A (zh) | 2018-06-11 | 2021-02-02 | 西雅图咖米公司 | 低血糖胶粘组合物及其制备和使用方法 |
| US20210227865A1 (en) | 2018-06-14 | 2021-07-29 | Seattle Gummy Company | Low glycemic composition and methods of making and using thereof |
| EP4364577A3 (en) | 2018-10-26 | 2024-06-19 | Intercontinental Great Brands LLC | Center-filled confectionery product; coated product; and methods of making |
| CN113747948B (zh) | 2019-04-26 | 2023-12-15 | 宝洁公司 | 减少来源于阳离子抗微生物剂的牙齿变色 |
| CN114173570A (zh) | 2019-08-14 | 2022-03-11 | 洲际大品牌有限责任公司 | 糖食片产品及其制备方法 |
| GB202012170D0 (en) * | 2020-08-05 | 2020-09-16 | Givaudan Sa | Organic compounds |
| MX2023003549A (es) | 2020-09-28 | 2023-04-21 | Procter & Gamble | Composiciones para el cuidado bucal que comprenden lupulo y saborizante. |
| US20230363407A1 (en) | 2020-10-09 | 2023-11-16 | Intercontinental Great Brands Llc | Unwrapped hard candy product; isomalt confectionery; method of making and use thereof |
| EP4337157A1 (en) | 2021-05-11 | 2024-03-20 | The Procter & Gamble Company | Oral care compositions comprising block copolymer |
| EP4144230B1 (en) | 2021-09-03 | 2024-08-07 | JT International SA | Chilled pouch material for nicotine pouch |
| US20250002704A1 (en) | 2021-10-06 | 2025-01-02 | Lubrizol Advanced Materials, Inc. | Stabilized rheology modifier emulsions |
| US20250241356A1 (en) | 2022-06-24 | 2025-07-31 | Michael S. Daniel | Oral composition comprising receptor modulator |
| WO2024179975A1 (en) | 2023-03-01 | 2024-09-06 | Perfetti Van Melle Benelux B.V. | Tooth whitening chewing gum; and methods of making the same |
| GB202303792D0 (en) | 2023-03-15 | 2023-04-26 | Givaudan Sa | Cosmetic composition |
| CN116924930B (zh) * | 2023-07-26 | 2025-07-01 | 上海应用技术大学 | 一种凉味剂n-乙基-2,2-二异丙基丁酰胺的纯化方法 |
| WO2025032120A1 (en) | 2023-08-10 | 2025-02-13 | Perfetti Van Melle Benelux Bv | Chewing gum comprising fiber; methods of making the same; and methods of use thereof |
| WO2025085892A2 (en) | 2023-10-18 | 2025-04-24 | Lubrizol Advanced Materials, Inc. | Sulfate-free personal care compositions |
| WO2025117353A1 (en) | 2023-11-30 | 2025-06-05 | Lubrizol Advanced Materials, Inc. | Crosslinked and hydrophobically modified xanthan gum |
| EP4585059A1 (en) | 2024-01-12 | 2025-07-16 | Nicoventures Trading Limited | Effervescent pouched product |
| EP4640075A1 (en) | 2024-04-22 | 2025-10-29 | Nicoventures Trading Limited | Oral pouched product with self-emulsifying delivery system |
| EP4678009A1 (en) | 2024-07-08 | 2026-01-14 | Nicoventures Trading Limited | Premix containing gelling agent for oral product |
| WO2026013602A1 (en) | 2024-07-10 | 2026-01-15 | Rai Strategic Holdings, Inc. | Oral products |
| WO2026033452A1 (en) | 2024-08-09 | 2026-02-12 | R. J. Reynolds Tobacco Company | Aerosol-generating consumable including sensate |
| WO2026047620A1 (en) | 2024-08-30 | 2026-03-05 | Rai Strategic Holdings, Inc. | Aerosolizable composition including a substituted 3-(1-methylpyrrolidin-2-yl)pyridine compound |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2186976A (en) * | 1940-01-16 | Tkialkylacetamides having satu | ||
| US1482343A (en) * | 1922-08-14 | 1924-01-29 | Farbwerke Vorm Meibter Lucius | Process of making alpha-alkylated acids and derivatives thereof |
| US1969828A (en) * | 1931-11-09 | 1934-08-14 | Abbott Lab | Sedative compounds |
| US2166119A (en) * | 1936-10-03 | 1939-07-18 | Du Pont | Insecticide |
| ES148410A1 (es) * | 1938-06-24 | 1941-11-01 | Ig Farbenindustrie Ag | MEDIOS HUMECTANTES PARA LEJiAS DE MERCERIZACIoN |
| FR1572332A (https=) * | 1968-04-05 | 1969-06-27 |
-
1972
- 1972-04-18 GB GB1791472A patent/GB1421743A/en not_active Expired
-
1973
- 1973-04-07 DE DE2317538A patent/DE2317538C2/de not_active Expired
- 1973-04-07 DE DE2366423A patent/DE2366423C2/de not_active Expired
- 1973-04-11 ZA ZA732515A patent/ZA732515B/xx unknown
- 1973-04-12 AU AU54429/73A patent/AU468442B2/en not_active Expired
- 1973-04-16 JP JP48042276A patent/JPS5935940B2/ja not_active Expired
- 1973-04-17 CA CA168,898A patent/CA984745A/en not_active Expired
- 1973-04-17 BE BE2052696A patent/BE798312A/xx not_active IP Right Cessation
- 1973-04-18 NL NLAANVRAGE7305509,A patent/NL181164C/xx not_active IP Right Cessation
- 1973-04-18 BR BR2825/73A patent/BR7302825D0/pt unknown
- 1973-04-18 FR FR7314111A patent/FR2180942B1/fr not_active Expired
-
1979
- 1979-05-07 US US06/036,662 patent/US4230688A/en not_active Expired - Lifetime
- 1979-06-28 HK HK431/79A patent/HK43179A/xx unknown
-
1980
- 1980-04-25 US US06/143,948 patent/US4296255A/en not_active Expired - Lifetime
Non-Patent Citations (1)
| Title |
|---|
| NICHTS-ERMITTELT |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3724900A1 (de) * | 1986-08-08 | 1988-03-10 | Colgate Palmolive Co | N-alkylneoalkanamide sowie diese enthaltenden zubereitungen |
| DE3724900C2 (de) * | 1986-08-08 | 2000-04-06 | Colgate Palmolive Co | N-Alkylneoalkanamide sowie deren Verwendung |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2366423C2 (de) | 1984-01-19 |
| HK43179A (en) | 1979-07-06 |
| FR2180942A1 (https=) | 1973-11-30 |
| BE798312A (fr) | 1973-10-17 |
| NL181164C (nl) | 1987-07-01 |
| JPS5935940B2 (ja) | 1984-08-31 |
| GB1421743A (en) | 1976-01-21 |
| JPS4919043A (https=) | 1974-02-20 |
| CA984745A (en) | 1976-03-02 |
| FR2180942B1 (https=) | 1978-01-13 |
| DE2317538A1 (de) | 1973-10-31 |
| AU468442B2 (en) | 1976-01-15 |
| BR7302825D0 (pt) | 1974-07-18 |
| NL7305509A (https=) | 1973-10-22 |
| DE2366423A1 (https=) | 1982-09-23 |
| US4296255A (en) | 1981-10-20 |
| US4230688A (en) | 1980-10-28 |
| ZA732515B (en) | 1974-02-27 |
| AU5442973A (en) | 1974-10-17 |
| NL181164B (nl) | 1987-02-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE2317538C2 (de) | Carbonsäureamide, Verfahren zu deren Herstellung und deren Verwendung | |
| DE2202535C3 (de) | Verwendung von p-Menthanderivaten | |
| DE2205255C3 (de) | N-substituierte p-Menthan-3-carbonsäureamide und sie enthaltende Mittel zur Stimulierung der Kaltrezeptoren des Nervensystems | |
| DE2516610C2 (de) | Verbrauchsprodukt mit physiologischer Kühlwirkung | |
| DE69314025T2 (de) | Zusammensetzungen mit kühleffekt | |
| US4070449A (en) | Compounds having a physiological cooling effect and compositions containing them | |
| US4157384A (en) | Compositions having a physiological cooling effect | |
| US4190643A (en) | Compositions having a physiological cooling effect | |
| US4136163A (en) | P-menthane carboxamides having a physiological cooling effect | |
| US4153679A (en) | Acyclic carboxamides having a physiological cooling effect | |
| US4032661A (en) | Cyclic sulphoxides and sulphones having a physiological cooling action on the human body | |
| US4296093A (en) | Cyclic carboxamides having a physiological cooling effect | |
| DE2309256A1 (de) | Mittel mit einem gehalt an eine kuehlende empfindung erzeugende verbindung | |
| DE2608226A1 (de) | Mittel mit physiologischer kuehlwirkung | |
| DE2624504A1 (de) | Mittel oder gegenstand mit die kaltrezeptoren des menschlichen nervensystems stimulierender wirkung | |
| US4136164A (en) | Certain substituted amides having a physiological cooling effect | |
| DE2413639A1 (de) | Cyclohexancarboxamide und sie enthaltende mittel | |
| DE2439770A1 (de) | Mittel mit physiologischer kuehlwirkung | |
| DE2317539C2 (de) | Cyclohexancarbonsäureamide und ihre Verwendung als Mittel zur Stimulierung der Kaltrezeptoren des menschlichen Nervensystems | |
| DE2458562C2 (de) | Verbrauchsprodukt mit einer die Kaltrezeptoren des Nervensystems stimulierenden Verbindung | |
| DE2317000A1 (de) | Mittel mit die kaltrezeptoren des menschlichen nervensystems stimulierender wirkung und deren verwendung | |
| EP2186506B1 (de) | Mentholhaltige Zahnputz-Zusammensetzung mit reduzierter Bitterwahrnehmung | |
| DE2316999A1 (de) | Mittel mit die kaltrezeptoren des menschlichen nervensystems stimulierender wirkung und deren verwendung | |
| DE2203273A1 (de) | Verwendung von p-Methandiolen zur Stimulierung der Kaltrezeptoren des menschlichen Nervensystems | |
| US4137304A (en) | Cyclic substituted ureas having a physiological cooling effect |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OD | Request for examination | ||
| 8172 | Supplementary division/partition in: |
Ref country code: DE Ref document number: 2366423 Format of ref document f/p: P |
|
| Q171 | Divided out to: |
Ref country code: DE Ref document number: 2366423 |
|
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| AH | Division in |
Ref country code: DE Ref document number: 2366423 Format of ref document f/p: P |