DE19375045I2 - Heterocyclische Verbindungen Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel - Google Patents

Heterocyclische Verbindungen Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Info

Publication number
DE19375045I2
DE19375045I2 DE1993175045 DE19375045C DE19375045I2 DE 19375045 I2 DE19375045 I2 DE 19375045I2 DE 1993175045 DE1993175045 DE 1993175045 DE 19375045 C DE19375045 C DE 19375045C DE 19375045 I2 DE19375045 I2 DE 19375045I2
Authority
DE
Germany
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
heterocyclic compounds
compounds process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE1993175045
Other languages
German (de)
English (en)
Inventor
Michael Dennis Dowle
Ian Harold Coates
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10530876&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE19375045(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE19375045I2 publication Critical patent/DE19375045I2/de
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DE1993175045 1982-06-07 1983-06-07 Heterocyclische Verbindungen Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel Active DE19375045I2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8216526 1982-06-07

Publications (1)

Publication Number Publication Date
DE19375045I2 true DE19375045I2 (de) 2002-09-05

Family

ID=10530876

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1993175045 Active DE19375045I2 (de) 1982-06-07 1983-06-07 Heterocyclische Verbindungen Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19833320521 Granted DE3320521A1 (de) 1982-06-07 1983-06-07 Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19833320521 Granted DE3320521A1 (de) 1982-06-07 1983-06-07 Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Country Status (33)

Country Link
US (1) US4816470A (en:Method)
JP (1) JPS5942366A (en:Method)
KR (1) KR900006681B1 (en:Method)
AT (1) AT381933B (en:Method)
AU (1) AU566149B2 (en:Method)
BE (1) BE896986A (en:Method)
CA (1) CA1199643A (en:Method)
CH (1) CH657359A5 (en:Method)
CY (1) CY1458A (en:Method)
CZ (1) CZ280529B6 (en:Method)
DE (2) DE19375045I2 (en:Method)
DK (1) DK260183D0 (en:Method)
DO (1) DOP1989476000A (en:Method)
ES (3) ES523039A0 (en:Method)
FI (1) FI79530C (en:Method)
FR (1) FR2530625B1 (en:Method)
GB (1) GB2124210B (en:Method)
GR (1) GR79215B (en:Method)
HK (1) HK14789A (en:Method)
IE (1) IE55358B1 (en:Method)
IL (1) IL68913A (en:Method)
IT (1) IT1170387B (en:Method)
KE (1) KE3833A (en:Method)
LU (1) LU84852A1 (en:Method)
MX (1) MX9202623A (en:Method)
MY (1) MY8700179A (en:Method)
NL (1) NL193694C (en:Method)
NZ (1) NZ204482A (en:Method)
PH (1) PH19908A (en:Method)
PT (1) PT76830B (en:Method)
SE (1) SE452459B (en:Method)
SK (1) SK277877B6 (en:Method)
ZA (1) ZA834110B (en:Method)

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US5270333A (en) * 1986-01-28 1993-12-14 Glaxo Group Limited Indole derivatives
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GB8615599D0 (en) * 1986-06-26 1986-07-30 Glaxo Group Ltd Chemical compounds
ATE92057T1 (de) * 1987-08-13 1993-08-15 Glaxo Group Ltd Indol-derivate.
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8903036D0 (en) * 1989-02-10 1989-03-30 Glaxo Group Ltd Chemical compounds
HUT57185A (en) * 1990-03-21 1991-11-28 Merrell Dow Pharma Process for producing 8-sulfamil-methylen-2-amino-tetraline derivatives and pharmaceutical compositions containing them
US5935925A (en) * 1990-05-08 1999-08-10 Synaptic Pharmaceutical Corporation Methods of treating migraine and compounds useful for such methods
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US5077293A (en) * 1990-06-29 1991-12-31 Bristol-Myers Squibb Co. 1-indolyalkyl-4-(alkoxypyrimidinyl)piperazines
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GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
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ES2055651B1 (es) * 1992-07-20 1995-03-01 Vita Invest Sa Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles.
GB9216009D0 (en) * 1992-07-28 1992-09-09 Almirall Lab New indol derivatives
ES2056025B1 (es) * 1992-10-08 1995-05-01 Almirall Lab Nuevos derivados de indol.
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FR2731224B1 (fr) * 1995-03-02 1997-05-30 Pf Medicament Nouveaux derives bi-tryptaminiques sulfonamides, leur procede de preparation et leur utilisation a titre de medicaments
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US20040068000A1 (en) * 2002-10-02 2004-04-08 Mintong Guo Compression coated tablets
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PT1575566E (pt) 2002-12-26 2012-03-29 Pozen Inc Formas de dosagem em multicamada contendo naproxeno e triptanos
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ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
SE454777B (sv) * 1980-08-12 1988-05-30 Glaxo Group Ltd 5-substituerade 3-aminoalkyl-1h-indoler, forfarande for framstellning av dessa och en farmaceutisk komposition for behandling av migren
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
FR2488607A1 (fr) * 1980-08-12 1982-02-19 Glaxo Group Ltd Derives de l'indole, leur preparation et leurs utilisations pharmaceutiques

Also Published As

Publication number Publication date
AT381933B (de) 1986-12-10
FI832035L (fi) 1983-12-08
FR2530625A1 (fr) 1984-01-27
KR900006681B1 (ko) 1990-09-17
DOP1989476000A (es) 1996-02-03
ES8609247A1 (es) 1986-07-16
IE55358B1 (en) 1990-08-29
KE3833A (en) 1988-11-18
SE8303208D0 (sv) 1983-06-07
IL68913A0 (en) 1983-10-31
ES8601880A1 (es) 1985-11-16
GB2124210A (en) 1984-02-15
GB2124210B (en) 1985-11-13
DK260183D0 (da) 1983-06-06
ES529802A0 (es) 1985-11-16
ATA208483A (de) 1986-05-15
IT8348422A0 (it) 1983-06-03
FI79530B (fi) 1989-09-29
JPH0329069B2 (en:Method) 1991-04-23
FI832035A0 (fi) 1983-06-07
SE452459B (sv) 1987-11-30
CA1199643A (en) 1986-01-21
IL68913A (en) 1987-08-31
HK14789A (en) 1989-02-24
DE3320521A1 (de) 1983-12-08
MX9202623A (es) 1992-06-30
NL193694C (nl) 2000-07-04
CY1458A (en) 1989-07-21
SE8303208L (sv) 1983-12-08
JPS5942366A (ja) 1984-03-08
PT76830A (en) 1983-07-01
ES8407473A1 (es) 1984-10-01
IE831335L (en) 1983-12-07
FI79530C (fi) 1990-01-10
NZ204482A (en) 1986-09-10
GR79215B (en:Method) 1984-10-22
AU1544183A (en) 1983-12-15
DE3320521C2 (en:Method) 1992-06-25
US4816470A (en) 1989-03-28
GB8315564D0 (en) 1983-07-13
AU566149B2 (en) 1987-10-08
FR2530625B1 (fr) 1986-04-18
IT1170387B (it) 1987-06-03
BE896986A (fr) 1983-12-07
KR840005095A (ko) 1984-11-03
PT76830B (en) 1986-04-21
ZA834110B (en) 1985-01-30
LU84852A1 (fr) 1985-03-29
CH657359A5 (fr) 1986-08-29
SK404091A3 (en) 1995-06-07
ES544281A0 (es) 1986-07-16
CZ404091A3 (en) 1993-04-14
NL8302031A (nl) 1984-01-02
ES523039A0 (es) 1984-10-01
CZ280529B6 (cs) 1996-02-14
NL193694B (nl) 2000-03-01
PH19908A (en) 1986-08-13
MY8700179A (en) 1987-12-31
SK277877B6 (en) 1995-06-07

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