AT381933B - Verfahren zur herstellung neuer indole und ihrer salze - Google Patents
Verfahren zur herstellung neuer indole und ihrer salzeInfo
- Publication number
- AT381933B AT381933B AT0208483A AT208483A AT381933B AT 381933 B AT381933 B AT 381933B AT 0208483 A AT0208483 A AT 0208483A AT 208483 A AT208483 A AT 208483A AT 381933 B AT381933 B AT 381933B
- Authority
- AT
- Austria
- Prior art keywords
- salts
- producing new
- new indoles
- indoles
- producing
- Prior art date
Links
- 150000002475 indoles Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8216526 | 1982-06-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA208483A ATA208483A (de) | 1986-05-15 |
AT381933B true AT381933B (de) | 1986-12-10 |
Family
ID=10530876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0208483A AT381933B (de) | 1982-06-07 | 1983-06-07 | Verfahren zur herstellung neuer indole und ihrer salze |
Country Status (33)
Country | Link |
---|---|
US (1) | US4816470A (de) |
JP (1) | JPS5942366A (de) |
KR (1) | KR900006681B1 (de) |
AT (1) | AT381933B (de) |
AU (1) | AU566149B2 (de) |
BE (1) | BE896986A (de) |
CA (1) | CA1199643A (de) |
CH (1) | CH657359A5 (de) |
CY (1) | CY1458A (de) |
CZ (1) | CZ280529B6 (de) |
DE (2) | DE19375045I2 (de) |
DK (1) | DK260183D0 (de) |
DO (1) | DOP1989476000A (de) |
ES (3) | ES8407473A1 (de) |
FI (1) | FI79530C (de) |
FR (1) | FR2530625B1 (de) |
GB (1) | GB2124210B (de) |
GR (1) | GR79215B (de) |
HK (1) | HK14789A (de) |
IE (1) | IE55358B1 (de) |
IL (1) | IL68913A (de) |
IT (1) | IT1170387B (de) |
KE (1) | KE3833A (de) |
LU (1) | LU84852A1 (de) |
MX (1) | MX9202623A (de) |
MY (1) | MY8700179A (de) |
NL (1) | NL193694C (de) |
NZ (1) | NZ204482A (de) |
PH (1) | PH19908A (de) |
PT (1) | PT76830B (de) |
SE (1) | SE452459B (de) |
SK (1) | SK277877B6 (de) |
ZA (1) | ZA834110B (de) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU196752B (en) * | 1983-12-06 | 1989-01-30 | Glaxo Group Ltd | Process for production of medical compositions containing indole-derivatives and these compounds |
GB8332434D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Production of chemical compounds |
GB8332437D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
GB8601959D0 (en) * | 1986-01-28 | 1986-03-05 | Glaxo Group Ltd | Indole derivatives |
US5270333A (en) * | 1986-01-28 | 1993-12-14 | Glaxo Group Limited | Indole derivatives |
GB8615599D0 (en) * | 1986-06-26 | 1986-07-30 | Glaxo Group Ltd | Chemical compounds |
GB8719167D0 (en) * | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
FI92397C (fi) * | 1987-08-13 | 1994-11-10 | Glaxo Group Ltd | Menetelmä valmistaa farmaseuttisesti käyttökelpoisia indolijohdoksia |
US5225431A (en) * | 1987-10-23 | 1993-07-06 | Burroughs Wellcome Co. | Therapeutic substituted indole compounds and compositions thereof |
GB8903036D0 (en) * | 1989-02-10 | 1989-03-30 | Glaxo Group Ltd | Chemical compounds |
HUT57185A (en) * | 1990-03-21 | 1991-11-28 | Merrell Dow Pharma | Process for producing 8-sulfamil-methylen-2-amino-tetraline derivatives and pharmaceutical compositions containing them |
US5935925A (en) * | 1990-05-08 | 1999-08-10 | Synaptic Pharmaceutical Corporation | Methods of treating migraine and compounds useful for such methods |
US5155218A (en) | 1990-05-08 | 1992-10-13 | Neurogenetic Corporation | Dna encoding human 5-ht1d receptors |
CZ288351B6 (en) * | 1990-06-07 | 2001-05-16 | Astrazeneca Ab | Nitrogenous heterocyclic compound, process of its preparation and use as well as a medicament containing thereof |
GB9013845D0 (en) * | 1990-06-21 | 1990-08-15 | Glaxo Group Ltd | Process |
CA2043709C (en) * | 1990-06-29 | 2002-01-22 | David W. Smith | Antimigraine alkoxypyrimidine derivatives |
US5077293A (en) * | 1990-06-29 | 1991-12-31 | Bristol-Myers Squibb Co. | 1-indolyalkyl-4-(alkoxypyrimidinyl)piperazines |
GB9022250D0 (en) * | 1990-10-12 | 1990-11-28 | Glaxo Group Ltd | Medicaments |
GB9103770D0 (en) * | 1991-02-22 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
GB9104890D0 (en) | 1991-03-08 | 1991-04-24 | Glaxo Group Ltd | Compositions |
CA2084531A1 (en) | 1991-12-19 | 1993-06-20 | David W. Smith | Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines |
GB9209882D0 (en) * | 1992-05-07 | 1992-06-24 | Glaxo Lab Sa | Compositions |
GB9211276D0 (en) * | 1992-05-28 | 1992-07-15 | Glaxo Lab Sa | Pharmaceutical compositions |
GB9211277D0 (en) | 1992-05-28 | 1992-07-15 | Glaxo Group Inc | Pharmaceutical compositions |
ES2055651B1 (es) * | 1992-07-20 | 1995-03-01 | Vita Invest Sa | Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles. |
GB9216009D0 (en) * | 1992-07-28 | 1992-09-09 | Almirall Lab | New indol derivatives |
ES2056025B1 (es) * | 1992-10-08 | 1995-05-01 | Almirall Lab | Nuevos derivados de indol. |
US5382592A (en) * | 1993-09-16 | 1995-01-17 | Bristol-Myers Squibb Company | Antimigraine cyclobutenedione derivatives of tryptamines |
US5468768A (en) * | 1994-01-06 | 1995-11-21 | Bristol-Myers Squibb Company | Antimigraine derivatives of indolylcycloalkanylamines |
ES2079323B1 (es) * | 1994-06-21 | 1996-10-16 | Vita Invest Sa | Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes. |
US5618816A (en) * | 1995-03-02 | 1997-04-08 | Bristol-Myers Squibb Company | Antimigraine 1,2,5-thiadiazole derivatives of indolylalkyl-pyridnyl and pyrimidinylpiperazines |
FR2731224B1 (fr) * | 1995-03-02 | 1997-05-30 | Pf Medicament | Nouveaux derives bi-tryptaminiques sulfonamides, leur procede de preparation et leur utilisation a titre de medicaments |
US5872145A (en) * | 1996-08-16 | 1999-02-16 | Pozen, Inc. | Formulation of 5-HT agonist and NSAID for treatment of migraine |
US8022095B2 (en) | 1996-08-16 | 2011-09-20 | Pozen, Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
US6586458B1 (en) | 1996-08-16 | 2003-07-01 | Pozen Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
US6416472B1 (en) | 1997-11-06 | 2002-07-09 | Edus Inc. | Method and device for measuring cognitive efficiency |
US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
US6066092A (en) * | 1997-11-06 | 2000-05-23 | Cady; Roger K. | Preemptive prophylaxis of migraine device and method |
GB9926250D0 (en) * | 1999-11-06 | 2000-01-12 | Knoll Ag | Chemical process |
WO2002015899A1 (en) * | 2000-08-23 | 2002-02-28 | Bristol-Myers Squibb Company | Combination therapy for the treatment of migraine |
NZ528377A (en) * | 2001-03-27 | 2005-05-27 | Galen Chemicals Ltd | Intravaginal drug delivery devices for the administration of an antimicrobial agent |
ES2312585T3 (es) * | 2001-06-05 | 2009-03-01 | Ronald Aung-Din | Terapia contra la migraña por via topica. |
US8329734B2 (en) * | 2009-07-27 | 2012-12-11 | Afgin Pharma Llc | Topical therapy for migraine |
EP2316468A1 (de) | 2002-02-22 | 2011-05-04 | Shire LLC | Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin |
WO2003105836A1 (en) * | 2002-06-13 | 2003-12-24 | Dr. Reddy's Laboratories Limited | 3-'2-(Dimethylamino) ethyl!-N-methyl-1H-indole-5-methanesulfonamide and the Succinate Thereof |
US20040068000A1 (en) * | 2002-10-02 | 2004-04-08 | Mintong Guo | Compression coated tablets |
EP2666772B1 (de) | 2002-12-20 | 2017-03-01 | Basf Se | Synthese von Aminen und Zwischenverbindungen für die Synthese davon |
AU2003303631B2 (en) | 2002-12-26 | 2008-05-29 | Nuvo Pharmaceuticals (Ireland) Designated Activity Company | Multilayer Dosage Forms Containing NSAIDs and Triptans |
US20080213363A1 (en) * | 2003-01-23 | 2008-09-04 | Singh Nikhilesh N | Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa |
WO2004076403A1 (en) * | 2003-02-24 | 2004-09-10 | Transform Pharmaceuticals, Inc. | Sumatriptan crystalline forms, pharmaceutical compositions and methods |
BRPI0410807A (pt) * | 2003-06-06 | 2006-06-27 | Glaxo Group Ltd | composição farmacêutica, e, método pata tratar um mamìfero sofrendo de ou susceptìvel a condições associadas com dor cefálica |
US20070065463A1 (en) * | 2003-06-20 | 2007-03-22 | Ronald Aung-Din | Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions |
MXPA06003452A (es) * | 2003-09-26 | 2006-08-31 | Johnson & Johnson | Formulaciones de liberacion controlada que exhiben una velocidad de liberacion ascendente. |
ATE504288T1 (de) * | 2003-09-26 | 2011-04-15 | Alza Corp | Oros-push-stick für die kontrollierte abgabe von wirkstoffen |
JP5563731B2 (ja) * | 2003-09-26 | 2014-07-30 | アルザ・コーポレーシヨン | オピオイドおよび非オピオイド鎮痛薬の制御放出製剤 |
EP2184058B1 (de) * | 2003-09-26 | 2012-02-08 | ALZA Corporation | Arzneistoffcoating mit hohem Wirkstoffanteil sowie Methoden zu dessen Herstellung |
EP1765300A2 (de) * | 2004-06-10 | 2007-03-28 | Duramed Pharmaceuticals, Inc. | Formulierungen von sumatriptan zur absorption durch biologische membranen, und herstellungs- und anwendungsverfahren |
US8541026B2 (en) * | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
CN101247853B (zh) | 2005-04-13 | 2014-11-12 | 轴突公司 | 具有nos抑制活性的取代的吲哚化合物 |
WO2007070504A2 (en) * | 2005-12-13 | 2007-06-21 | Morton Grove Pharmaceuticals, Inc. | Stable and palatable oral liquid sumatriptan compositions |
TW200808780A (en) * | 2006-04-13 | 2008-02-16 | Neuraxon Inc | 1,5 and 3,6- substituted indole compounds having NOS inhibitory activity |
US20080103189A1 (en) * | 2006-10-19 | 2008-05-01 | Auspex Pharmaceuticals, Inc. | Preparation and utility of substituted indoles |
CA2705833A1 (en) * | 2007-11-16 | 2009-05-22 | Subhash C. Annedi | 3,5-substituted indole compounds having nos and norepinephrine reuptake inhibitory activity |
JP2011503120A (ja) * | 2007-11-16 | 2011-01-27 | ニューラクソン,インコーポレーテッド | 内臓痛を治療するためのインドール化合物および方法 |
WO2009064505A1 (en) * | 2007-11-16 | 2009-05-22 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods for treating visceral pain |
US20090252791A1 (en) * | 2008-04-02 | 2009-10-08 | Venkata Nookaraju Sreedharala | Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug |
CA2725618C (en) | 2008-05-27 | 2016-04-12 | Biota Scientific Management Pty Ltd | Antiviral salts |
EP2306998A4 (de) * | 2008-06-20 | 2011-06-15 | Alphapharm Pty Ltd | Pharmazeutische formulierung |
AU2009269129B2 (en) * | 2008-06-30 | 2015-08-20 | Afgin Pharma, Llc | Topical regional neuro-affective therapy |
WO2011036521A2 (en) | 2009-09-25 | 2011-03-31 | Dr. Reddy's Laboratories Limited | Formulations comprising triptan compounds |
US11337962B2 (en) | 2009-09-25 | 2022-05-24 | Upsher-Smith Laboratories, Llc | Formulations comprising triptan compounds |
JP2018507262A (ja) | 2015-03-02 | 2018-03-15 | アフギン ファーマ, エルエルシーAfgin Pharma, Llc | カンナビノイドを用いた、局所局部的神経作用療法 |
US10383816B2 (en) | 2015-03-02 | 2019-08-20 | Afgin Pharma, Llc | Topical regional neuro-affective therapy with cannabinoid combination products |
US10537554B2 (en) | 2015-08-05 | 2020-01-21 | Upsher-Smith Laboratories, Llc | Pharmaceutical composition for treating migraine |
JP7126260B2 (ja) | 2016-01-27 | 2022-08-26 | インスター テクノロジーズ アクチオヴァ スプルチュノスト | 治療処置用の口腔粘膜ナノファイバ担体 |
US20180049994A1 (en) | 2016-08-16 | 2018-02-22 | Afgin Pharma, Llc | Topical regional neuro-affective therapy with caryophyllene |
EP3766483A1 (de) | 2019-07-19 | 2021-01-20 | BioPharma Synergies, S. L. | Orodispergierbare pulverzusammensetzung mit einem triptan |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2940687A1 (de) * | 1978-10-12 | 1980-04-30 | Glaxo Group Ltd | Indolverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3131728A1 (de) * | 1980-08-12 | 1982-03-11 | Glaxo Group Ltd., London | Indolverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZW19381A1 (en) * | 1980-08-12 | 1983-03-09 | Glaxo Group Ltd | Heterocyclic compounds |
GB2082175B (en) * | 1980-08-12 | 1984-05-02 | Glaxo Group Ltd | Heterocyclic compounds |
NZ197998A (en) * | 1980-08-12 | 1985-08-16 | Glaxo Group Ltd | 5-amino(methyl)-1h-indol-3-ylalkaneamines |
-
1983
- 1983-06-03 IT IT48422/83A patent/IT1170387B/it active Protection Beyond IP Right Term
- 1983-06-03 GR GR71558A patent/GR79215B/el unknown
- 1983-06-06 DK DK2601/83A patent/DK260183D0/da not_active Application Discontinuation
- 1983-06-07 AT AT0208483A patent/AT381933B/de not_active IP Right Cessation
- 1983-06-07 IE IE1335/83A patent/IE55358B1/en not_active IP Right Cessation
- 1983-06-07 CH CH3117/83A patent/CH657359A5/fr not_active IP Right Cessation
- 1983-06-07 BE BE0/210953A patent/BE896986A/fr not_active IP Right Cessation
- 1983-06-07 ZA ZA834110A patent/ZA834110B/xx unknown
- 1983-06-07 PH PH29020A patent/PH19908A/en unknown
- 1983-06-07 LU LU84852A patent/LU84852A1/fr unknown
- 1983-06-07 DE DE1993175045 patent/DE19375045I2/de active Active
- 1983-06-07 NZ NZ204482A patent/NZ204482A/en unknown
- 1983-06-07 NL NL8302031A patent/NL193694C/nl not_active IP Right Cessation
- 1983-06-07 IL IL68913A patent/IL68913A/xx not_active IP Right Cessation
- 1983-06-07 DE DE19833320521 patent/DE3320521A1/de active Granted
- 1983-06-07 AU AU15441/83A patent/AU566149B2/en not_active Expired
- 1983-06-07 CA CA000429902A patent/CA1199643A/en not_active Expired
- 1983-06-07 KR KR1019830002526A patent/KR900006681B1/ko not_active IP Right Cessation
- 1983-06-07 SE SE8303208A patent/SE452459B/sv not_active IP Right Cessation
- 1983-06-07 GB GB08315564A patent/GB2124210B/en not_active Expired
- 1983-06-07 ES ES523039A patent/ES8407473A1/es not_active Expired
- 1983-06-07 FI FI832035A patent/FI79530C/fi not_active IP Right Cessation
- 1983-06-07 FR FR8309429A patent/FR2530625B1/fr not_active Expired
- 1983-06-07 JP JP58101587A patent/JPS5942366A/ja active Granted
- 1983-06-07 PT PT76830A patent/PT76830B/pt unknown
-
1984
- 1984-02-16 ES ES529802A patent/ES8601880A1/es not_active Expired
-
1985
- 1985-06-17 ES ES544281A patent/ES8609247A1/es not_active Expired
- 1985-11-15 US US06/789,831 patent/US4816470A/en not_active Expired - Lifetime
-
1987
- 1987-12-30 MY MY179/87A patent/MY8700179A/xx unknown
-
1988
- 1988-09-30 KE KE3833A patent/KE3833A/xx unknown
-
1989
- 1989-02-16 HK HK147/89A patent/HK14789A/xx not_active IP Right Cessation
- 1989-07-21 CY CY1458A patent/CY1458A/xx unknown
- 1989-11-20 DO DO4760001989A patent/DOP1989476000A/es unknown
-
1991
- 1991-12-23 SK SK4040-91A patent/SK277877B6/sk unknown
- 1991-12-23 CZ CS914040A patent/CZ280529B6/cs unknown
-
1992
- 1992-06-02 MX MX9202623A patent/MX9202623A/es unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2940687A1 (de) * | 1978-10-12 | 1980-04-30 | Glaxo Group Ltd | Indolverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3131728A1 (de) * | 1980-08-12 | 1982-03-11 | Glaxo Group Ltd., London | Indolverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
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