IL68913A - 3-aminoalkyl-1h-indole-5-alkan-sulphonamide derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

3-aminoalkyl-1h-indole-5-alkan-sulphonamide derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL68913A
IL68913A IL68913A IL6891383A IL68913A IL 68913 A IL68913 A IL 68913A IL 68913 A IL68913 A IL 68913A IL 6891383 A IL6891383 A IL 6891383A IL 68913 A IL68913 A IL 68913A
Authority
IL
Israel
Prior art keywords
alkan
aminoalkyl
indole
preparation
pharmaceutical compositions
Prior art date
Application number
IL68913A
Other languages
English (en)
Other versions
IL68913A0 (en
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10530876&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL68913(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IL68913A0 publication Critical patent/IL68913A0/xx
Publication of IL68913A publication Critical patent/IL68913A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
IL68913A 1982-06-07 1983-06-07 3-aminoalkyl-1h-indole-5-alkan-sulphonamide derivatives,their preparation and pharmaceutical compositions containing them IL68913A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8216526 1982-06-07

Publications (2)

Publication Number Publication Date
IL68913A0 IL68913A0 (en) 1983-10-31
IL68913A true IL68913A (en) 1987-08-31

Family

ID=10530876

Family Applications (1)

Application Number Title Priority Date Filing Date
IL68913A IL68913A (en) 1982-06-07 1983-06-07 3-aminoalkyl-1h-indole-5-alkan-sulphonamide derivatives,their preparation and pharmaceutical compositions containing them

Country Status (33)

Country Link
US (1) US4816470A (xx)
JP (1) JPS5942366A (xx)
KR (1) KR900006681B1 (xx)
AT (1) AT381933B (xx)
AU (1) AU566149B2 (xx)
BE (1) BE896986A (xx)
CA (1) CA1199643A (xx)
CH (1) CH657359A5 (xx)
CY (1) CY1458A (xx)
CZ (1) CZ280529B6 (xx)
DE (2) DE3320521A1 (xx)
DK (1) DK260183D0 (xx)
DO (1) DOP1989476000A (xx)
ES (3) ES8407473A1 (xx)
FI (1) FI79530C (xx)
FR (1) FR2530625B1 (xx)
GB (1) GB2124210B (xx)
GR (1) GR79215B (xx)
HK (1) HK14789A (xx)
IE (1) IE55358B1 (xx)
IL (1) IL68913A (xx)
IT (1) IT1170387B (xx)
KE (1) KE3833A (xx)
LU (1) LU84852A1 (xx)
MX (1) MX9202623A (xx)
MY (1) MY8700179A (xx)
NL (1) NL193694C (xx)
NZ (1) NZ204482A (xx)
PH (1) PH19908A (xx)
PT (1) PT76830B (xx)
SE (1) SE452459B (xx)
SK (1) SK277877B6 (xx)
ZA (1) ZA834110B (xx)

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US5270333A (en) * 1986-01-28 1993-12-14 Glaxo Group Limited Indole derivatives
GB8615599D0 (en) * 1986-06-26 1986-07-30 Glaxo Group Ltd Chemical compounds
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
KR0131327B1 (en) * 1987-08-13 1998-04-17 Glaxo Group Ltd Indole derivatives
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8903036D0 (en) * 1989-02-10 1989-03-30 Glaxo Group Ltd Chemical compounds
HUT57185A (en) * 1990-03-21 1991-11-28 Merrell Dow Pharma Process for producing 8-sulfamil-methylen-2-amino-tetraline derivatives and pharmaceutical compositions containing them
US5155218A (en) * 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors
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GB9013845D0 (en) * 1990-06-21 1990-08-15 Glaxo Group Ltd Process
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CA2043709C (en) * 1990-06-29 2002-01-22 David W. Smith Antimigraine alkoxypyrimidine derivatives
GB9022250D0 (en) * 1990-10-12 1990-11-28 Glaxo Group Ltd Medicaments
GB9103770D0 (en) * 1991-02-22 1991-04-10 Glaxo Group Ltd Chemical compounds
GB9104890D0 (en) * 1991-03-08 1991-04-24 Glaxo Group Ltd Compositions
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GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
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ES2055651B1 (es) * 1992-07-20 1995-03-01 Vita Invest Sa Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles.
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US5618816A (en) * 1995-03-02 1997-04-08 Bristol-Myers Squibb Company Antimigraine 1,2,5-thiadiazole derivatives of indolylalkyl-pyridnyl and pyrimidinylpiperazines
FR2731224B1 (fr) * 1995-03-02 1997-05-30 Pf Medicament Nouveaux derives bi-tryptaminiques sulfonamides, leur procede de preparation et leur utilisation a titre de medicaments
US8022095B2 (en) 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US6586458B1 (en) 1996-08-16 2003-07-01 Pozen Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US5872145A (en) * 1996-08-16 1999-02-16 Pozen, Inc. Formulation of 5-HT agonist and NSAID for treatment of migraine
US6066092A (en) * 1997-11-06 2000-05-23 Cady; Roger K. Preemptive prophylaxis of migraine device and method
US6416472B1 (en) 1997-11-06 2002-07-09 Edus Inc. Method and device for measuring cognitive efficiency
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
GB9926250D0 (en) * 1999-11-06 2000-01-12 Knoll Ag Chemical process
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US20040068000A1 (en) * 2002-10-02 2004-04-08 Mintong Guo Compression coated tablets
CN1729174B (zh) 2002-12-20 2015-10-21 西巴特殊化学品控股有限公司 胺的合成以及用于合成胺的中间体
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US20090252791A1 (en) * 2008-04-02 2009-10-08 Venkata Nookaraju Sreedharala Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug
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US8592424B2 (en) * 2008-06-30 2013-11-26 Afgin Pharma Llc Topical regional neuro-affective therapy
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
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US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
US10716766B2 (en) 2015-03-02 2020-07-21 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoids
US10537554B2 (en) * 2015-08-05 2020-01-21 Upsher-Smith Laboratories, Llc Pharmaceutical composition for treating migraine
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ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
GB2083463B (en) * 1980-08-12 1984-05-10 Glaxo Group Ltd Heterocyclic compounds
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
BE889929A (fr) * 1980-08-12 1982-02-11 Glaxo Group Ltd Derives de l'indole, leur preparation et leurs utilisations therapeutiques
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
ZA834110B (en) 1985-01-30
IE55358B1 (en) 1990-08-29
NL8302031A (nl) 1984-01-02
ES529802A0 (es) 1985-11-16
AT381933B (de) 1986-12-10
NL193694C (nl) 2000-07-04
FI79530C (fi) 1990-01-10
US4816470A (en) 1989-03-28
ES523039A0 (es) 1984-10-01
KR840005095A (ko) 1984-11-03
GB8315564D0 (en) 1983-07-13
IL68913A0 (en) 1983-10-31
IT8348422A0 (it) 1983-06-03
FR2530625B1 (fr) 1986-04-18
NL193694B (nl) 2000-03-01
NZ204482A (en) 1986-09-10
BE896986A (fr) 1983-12-07
ES8609247A1 (es) 1986-07-16
CY1458A (en) 1989-07-21
KE3833A (en) 1988-11-18
SE8303208L (sv) 1983-12-08
KR900006681B1 (ko) 1990-09-17
PT76830A (en) 1983-07-01
LU84852A1 (fr) 1985-03-29
GB2124210B (en) 1985-11-13
FI832035L (fi) 1983-12-08
DE3320521A1 (de) 1983-12-08
FI79530B (fi) 1989-09-29
DE3320521C2 (xx) 1992-06-25
CH657359A5 (fr) 1986-08-29
SE8303208D0 (sv) 1983-06-07
MY8700179A (en) 1987-12-31
JPH0329069B2 (xx) 1991-04-23
GB2124210A (en) 1984-02-15
ES8407473A1 (es) 1984-10-01
CA1199643A (en) 1986-01-21
IT1170387B (it) 1987-06-03
PT76830B (en) 1986-04-21
GR79215B (xx) 1984-10-22
DOP1989476000A (es) 1996-02-03
ES8601880A1 (es) 1985-11-16
AU566149B2 (en) 1987-10-08
SK404091A3 (en) 1995-06-07
JPS5942366A (ja) 1984-03-08
MX9202623A (es) 1992-06-30
FI832035A0 (fi) 1983-06-07
FR2530625A1 (fr) 1984-01-27
HK14789A (en) 1989-02-24
CZ280529B6 (cs) 1996-02-14
PH19908A (en) 1986-08-13
IE831335L (en) 1983-12-07
SK277877B6 (en) 1995-06-07
ES544281A0 (es) 1986-07-16
DE19375045I2 (de) 2002-09-05
ATA208483A (de) 1986-05-15
DK260183D0 (da) 1983-06-06
CZ404091A3 (en) 1993-04-14
AU1544183A (en) 1983-12-15
SE452459B (sv) 1987-11-30

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