ES529802A0 - Un procedimiento para la preparacion de derivados del indol - Google Patents

Un procedimiento para la preparacion de derivados del indol

Info

Publication number
ES529802A0
ES529802A0 ES529802A ES529802A ES529802A0 ES 529802 A0 ES529802 A0 ES 529802A0 ES 529802 A ES529802 A ES 529802A ES 529802 A ES529802 A ES 529802A ES 529802 A0 ES529802 A0 ES 529802A0
Authority
ES
Spain
Prior art keywords
procedure
preparation
indol derivatives
indol
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES529802A
Other languages
English (en)
Other versions
ES8601880A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10530876&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES529802(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES529802A0 publication Critical patent/ES529802A0/es
Publication of ES8601880A1 publication Critical patent/ES8601880A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
ES529802A 1982-06-07 1984-02-16 Un procedimiento para la preparacion de derivados del indol Expired ES8601880A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8216526 1982-06-07

Publications (2)

Publication Number Publication Date
ES529802A0 true ES529802A0 (es) 1985-11-16
ES8601880A1 ES8601880A1 (es) 1985-11-16

Family

ID=10530876

Family Applications (3)

Application Number Title Priority Date Filing Date
ES523039A Expired ES8407473A1 (es) 1982-06-07 1983-06-07 "un procedimiento para la preparacion de derivados del indol"
ES529802A Expired ES8601880A1 (es) 1982-06-07 1984-02-16 Un procedimiento para la preparacion de derivados del indol
ES544281A Expired ES8609247A1 (es) 1982-06-07 1985-06-17 Un procedimiento para la preparacion de derivados del indol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES523039A Expired ES8407473A1 (es) 1982-06-07 1983-06-07 "un procedimiento para la preparacion de derivados del indol"

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES544281A Expired ES8609247A1 (es) 1982-06-07 1985-06-17 Un procedimiento para la preparacion de derivados del indol

Country Status (33)

Country Link
US (1) US4816470A (es)
JP (1) JPS5942366A (es)
KR (1) KR900006681B1 (es)
AT (1) AT381933B (es)
AU (1) AU566149B2 (es)
BE (1) BE896986A (es)
CA (1) CA1199643A (es)
CH (1) CH657359A5 (es)
CY (1) CY1458A (es)
CZ (1) CZ280529B6 (es)
DE (2) DE3320521A1 (es)
DK (1) DK260183D0 (es)
DO (1) DOP1989476000A (es)
ES (3) ES8407473A1 (es)
FI (1) FI79530C (es)
FR (1) FR2530625B1 (es)
GB (1) GB2124210B (es)
GR (1) GR79215B (es)
HK (1) HK14789A (es)
IE (1) IE55358B1 (es)
IL (1) IL68913A (es)
IT (1) IT1170387B (es)
KE (1) KE3833A (es)
LU (1) LU84852A1 (es)
MX (1) MX9202623A (es)
MY (1) MY8700179A (es)
NL (1) NL193694C (es)
NZ (1) NZ204482A (es)
PH (1) PH19908A (es)
PT (1) PT76830B (es)
SE (1) SE452459B (es)
SK (1) SK277877B6 (es)
ZA (1) ZA834110B (es)

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US5270333A (en) * 1986-01-28 1993-12-14 Glaxo Group Limited Indole derivatives
GB8615599D0 (en) * 1986-06-26 1986-07-30 Glaxo Group Ltd Chemical compounds
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
KR0131327B1 (en) * 1987-08-13 1998-04-17 Glaxo Group Ltd Indole derivatives
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US5155218A (en) * 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors
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GB9022250D0 (en) * 1990-10-12 1990-11-28 Glaxo Group Ltd Medicaments
GB9103770D0 (en) * 1991-02-22 1991-04-10 Glaxo Group Ltd Chemical compounds
GB9104890D0 (en) * 1991-03-08 1991-04-24 Glaxo Group Ltd Compositions
CA2084531A1 (en) * 1991-12-19 1993-06-20 David W. Smith Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines
GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
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GB9211276D0 (en) * 1992-05-28 1992-07-15 Glaxo Lab Sa Pharmaceutical compositions
ES2055651B1 (es) * 1992-07-20 1995-03-01 Vita Invest Sa Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles.
GB9216009D0 (en) * 1992-07-28 1992-09-09 Almirall Lab New indol derivatives
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US5618816A (en) * 1995-03-02 1997-04-08 Bristol-Myers Squibb Company Antimigraine 1,2,5-thiadiazole derivatives of indolylalkyl-pyridnyl and pyrimidinylpiperazines
FR2731224B1 (fr) * 1995-03-02 1997-05-30 Pf Medicament Nouveaux derives bi-tryptaminiques sulfonamides, leur procede de preparation et leur utilisation a titre de medicaments
US8022095B2 (en) 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US6586458B1 (en) 1996-08-16 2003-07-01 Pozen Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US5872145A (en) * 1996-08-16 1999-02-16 Pozen, Inc. Formulation of 5-HT agonist and NSAID for treatment of migraine
US6066092A (en) * 1997-11-06 2000-05-23 Cady; Roger K. Preemptive prophylaxis of migraine device and method
US6416472B1 (en) 1997-11-06 2002-07-09 Edus Inc. Method and device for measuring cognitive efficiency
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
GB9926250D0 (en) * 1999-11-06 2000-01-12 Knoll Ag Chemical process
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US20040068000A1 (en) * 2002-10-02 2004-04-08 Mintong Guo Compression coated tablets
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US20090252791A1 (en) * 2008-04-02 2009-10-08 Venkata Nookaraju Sreedharala Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug
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US8618157B2 (en) * 2008-06-20 2013-12-31 Alphapharm Pty. Ltd. Pharmaceutical formulation
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US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
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US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
US10716766B2 (en) 2015-03-02 2020-07-21 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoids
US10537554B2 (en) * 2015-08-05 2020-01-21 Upsher-Smith Laboratories, Llc Pharmaceutical composition for treating migraine
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* Cited by examiner, † Cited by third party
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ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
GB2083463B (en) * 1980-08-12 1984-05-10 Glaxo Group Ltd Heterocyclic compounds
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
BE889929A (fr) * 1980-08-12 1982-02-11 Glaxo Group Ltd Derives de l'indole, leur preparation et leurs utilisations therapeutiques
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
ZA834110B (en) 1985-01-30
IE55358B1 (en) 1990-08-29
NL8302031A (nl) 1984-01-02
AT381933B (de) 1986-12-10
NL193694C (nl) 2000-07-04
FI79530C (fi) 1990-01-10
US4816470A (en) 1989-03-28
ES523039A0 (es) 1984-10-01
KR840005095A (ko) 1984-11-03
GB8315564D0 (en) 1983-07-13
IL68913A0 (en) 1983-10-31
IT8348422A0 (it) 1983-06-03
FR2530625B1 (fr) 1986-04-18
NL193694B (nl) 2000-03-01
NZ204482A (en) 1986-09-10
BE896986A (fr) 1983-12-07
ES8609247A1 (es) 1986-07-16
CY1458A (en) 1989-07-21
KE3833A (en) 1988-11-18
SE8303208L (sv) 1983-12-08
KR900006681B1 (ko) 1990-09-17
PT76830A (en) 1983-07-01
LU84852A1 (fr) 1985-03-29
GB2124210B (en) 1985-11-13
FI832035L (fi) 1983-12-08
DE3320521A1 (de) 1983-12-08
FI79530B (fi) 1989-09-29
DE3320521C2 (es) 1992-06-25
CH657359A5 (fr) 1986-08-29
SE8303208D0 (sv) 1983-06-07
MY8700179A (en) 1987-12-31
JPH0329069B2 (es) 1991-04-23
GB2124210A (en) 1984-02-15
ES8407473A1 (es) 1984-10-01
CA1199643A (en) 1986-01-21
IT1170387B (it) 1987-06-03
PT76830B (en) 1986-04-21
GR79215B (es) 1984-10-22
DOP1989476000A (es) 1996-02-03
ES8601880A1 (es) 1985-11-16
AU566149B2 (en) 1987-10-08
SK404091A3 (en) 1995-06-07
JPS5942366A (ja) 1984-03-08
MX9202623A (es) 1992-06-30
FI832035A0 (fi) 1983-06-07
IL68913A (en) 1987-08-31
FR2530625A1 (fr) 1984-01-27
HK14789A (en) 1989-02-24
CZ280529B6 (cs) 1996-02-14
PH19908A (en) 1986-08-13
IE831335L (en) 1983-12-07
SK277877B6 (en) 1995-06-07
ES544281A0 (es) 1986-07-16
DE19375045I2 (de) 2002-09-05
ATA208483A (de) 1986-05-15
DK260183D0 (da) 1983-06-06
CZ404091A3 (en) 1993-04-14
AU1544183A (en) 1983-12-15
SE452459B (sv) 1987-11-30

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