DE1917128A1 - Verfahren zur Herstellung von 1-Acylindolyl-3-alkanalen - Google Patents

Verfahren zur Herstellung von 1-Acylindolyl-3-alkanalen

Info

Publication number
DE1917128A1
DE1917128A1 DE19691917128 DE1917128A DE1917128A1 DE 1917128 A1 DE1917128 A1 DE 1917128A1 DE 19691917128 DE19691917128 DE 19691917128 DE 1917128 A DE1917128 A DE 1917128A DE 1917128 A1 DE1917128 A1 DE 1917128A1
Authority
DE
Germany
Prior art keywords
acid
hydrogen
hydroxy
methyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19691917128
Other languages
German (de)
English (en)
Inventor
Hinkley David Fred
George Gal
Clamkowski Edward Joseph
Brenner Gerald Stanley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1917128A1 publication Critical patent/DE1917128A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19691917128 1968-04-09 1969-04-02 Verfahren zur Herstellung von 1-Acylindolyl-3-alkanalen Pending DE1917128A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA17167 1968-04-09

Publications (1)

Publication Number Publication Date
DE1917128A1 true DE1917128A1 (de) 1969-10-23

Family

ID=4084168

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19691917128 Pending DE1917128A1 (de) 1968-04-09 1969-04-02 Verfahren zur Herstellung von 1-Acylindolyl-3-alkanalen

Country Status (5)

Country Link
CH (1) CH521965A (enExample)
DE (1) DE1917128A1 (enExample)
FR (1) FR2005861A1 (enExample)
GB (1) GB1226462A (enExample)
NL (1) NL6904772A (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11738004B2 (en) 2011-10-17 2023-08-29 Vanderbilt University Indomethacin analogs for the treatment of castrate-resistant prostate cancer
EP4271682A4 (en) * 2020-12-31 2025-03-12 1280225 B.C. Ltd. Method of synthesizing indole compounds

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11738004B2 (en) 2011-10-17 2023-08-29 Vanderbilt University Indomethacin analogs for the treatment of castrate-resistant prostate cancer
EP4271682A4 (en) * 2020-12-31 2025-03-12 1280225 B.C. Ltd. Method of synthesizing indole compounds
US12331020B2 (en) 2020-12-31 2025-06-17 1280225 B.C. Ltd. Method of synthesizing indole compounds

Also Published As

Publication number Publication date
GB1226462A (enExample) 1971-03-31
NL6904772A (enExample) 1969-10-13
FR2005861A1 (enExample) 1969-12-19
CH521965A (de) 1972-04-30

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