DE1153487B - Verfahren zur Herstellung einer Lebendvaccine gegen Maul- und Klauenseuche - Google Patents
Verfahren zur Herstellung einer Lebendvaccine gegen Maul- und KlauenseucheInfo
- Publication number
- DE1153487B DE1153487B DEF36008A DEF0036008A DE1153487B DE 1153487 B DE1153487 B DE 1153487B DE F36008 A DEF36008 A DE F36008A DE F0036008 A DEF0036008 A DE F0036008A DE 1153487 B DE1153487 B DE 1153487B
- Authority
- DE
- Germany
- Prior art keywords
- virus
- mouth disease
- live vaccine
- fmd
- vaccine against
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960005486 vaccine Drugs 0.000 title claims description 14
- 241000710198 Foot-and-mouth disease virus Species 0.000 title claims description 7
- 238000000034 method Methods 0.000 title claims description 7
- 208000007212 Foot-and-Mouth Disease Diseases 0.000 title claims description 3
- 238000004519 manufacturing process Methods 0.000 title description 5
- 241000700605 Viruses Species 0.000 claims description 14
- 241000283690 Bos taurus Species 0.000 claims description 12
- 241001465754 Metazoa Species 0.000 claims description 12
- 238000004113 cell culture Methods 0.000 claims description 6
- 230000002238 attenuated effect Effects 0.000 claims description 5
- 201000010099 disease Diseases 0.000 claims description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 2
- 238000007792 addition Methods 0.000 claims description 2
- 229910052799 carbon Inorganic materials 0.000 claims description 2
- 210000002308 embryonic cell Anatomy 0.000 claims description 2
- 210000000981 epithelium Anatomy 0.000 claims description 2
- 239000007924 injection Substances 0.000 claims description 2
- 238000002347 injection Methods 0.000 claims description 2
- 210000003734 kidney Anatomy 0.000 claims description 2
- 229910052757 nitrogen Inorganic materials 0.000 claims description 2
- 239000002504 physiological saline solution Substances 0.000 claims description 2
- 102000004169 proteins and genes Human genes 0.000 claims description 2
- 108090000623 proteins and genes Proteins 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims 1
- 230000000007 visual effect Effects 0.000 claims 1
- 238000012360 testing method Methods 0.000 description 13
- 208000015181 infectious disease Diseases 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 4
- 238000006386 neutralization reaction Methods 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- 238000002255 vaccination Methods 0.000 description 3
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102000004407 Lactalbumin Human genes 0.000 description 1
- 108090000942 Lactalbumin Proteins 0.000 description 1
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000030194 mouth disease Diseases 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229960003531 phenolsulfonphthalein Drugs 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 239000005723 virus inoculator Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
- A61K39/135—Foot- and mouth-disease virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
- C12N2770/32134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
- C12N2770/32151—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF36008A DE1153487B (de) | 1962-02-13 | 1962-02-13 | Verfahren zur Herstellung einer Lebendvaccine gegen Maul- und Klauenseuche |
| FI630070A FI41590C (fi) | 1962-02-13 | 1963-01-15 | Menetelmä elävän rokotteen valmistamiseksi suu- ja sorkkatautia vastaan |
| GB4222/63A GB969432A (en) | 1962-02-13 | 1963-02-01 | Process for the production of a live vaccine against foot-and-mouth disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF36008A DE1153487B (de) | 1962-02-13 | 1962-02-13 | Verfahren zur Herstellung einer Lebendvaccine gegen Maul- und Klauenseuche |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1153487B true DE1153487B (de) | 1963-08-29 |
Family
ID=7096279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DEF36008A Pending DE1153487B (de) | 1962-02-13 | 1962-02-13 | Verfahren zur Herstellung einer Lebendvaccine gegen Maul- und Klauenseuche |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE1153487B (cs) |
| FI (1) | FI41590C (cs) |
| GB (1) | GB969432A (cs) |
-
1962
- 1962-02-13 DE DEF36008A patent/DE1153487B/de active Pending
-
1963
- 1963-01-15 FI FI630070A patent/FI41590C/fi active
- 1963-02-01 GB GB4222/63A patent/GB969432A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI41590C (fi) | 1969-12-10 |
| FI41590B (cs) | 1969-09-01 |
| GB969432A (en) | 1964-09-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE2817891A1 (de) | Nd-impfstoff und verfahren zu seiner herstellung | |
| DE1198489B (de) | Verfahren zur Herstellung eines Impfstoffes gegen Panleucopenie | |
| DE2456636A1 (de) | Influenza-vakzine und verfahren zu ihrer herstellung | |
| CH423095A (de) | Verfahren zur Herstellung eines Tollwutimpfstoffes | |
| DE1153487B (de) | Verfahren zur Herstellung einer Lebendvaccine gegen Maul- und Klauenseuche | |
| DE2602478C3 (de) | Impfstoff gegen die Panleukopenie der Feliden | |
| DE2058645A1 (de) | Verfahren zur Herstellung von abgeschwaechter Newcastle-Disease-Virus-Lebendvaccine | |
| DE2805311A1 (de) | Respiratorische synzytial-vakzine | |
| DE1235505B (de) | Verfahren zur Herstellung einer Vaccine gegen Staupe | |
| DE1174016B (de) | Verfahren zur Herstellung einer Lebend-Vaccine gegen Maul- und Klauenseuche | |
| DE2702634A1 (de) | Verfahren zur herstellung einer vaccine gegen die panleukopenie der katze | |
| DE499512C (de) | Verfahren zur Herstellung von oertlich anzuwendenden, aus Bakterienkulturen, z.B. Staphylokokken-, Streptokokkenkulturen usw. gewonnenen, selbst aber bakterienfreien, sterilen, hochbestaendigen Impfstoffen (Topovaccinen) | |
| DE2328579A1 (de) | Varicella-vaccine | |
| WO1989005154A1 (fr) | Procede pour la preparation d'un virus avirulent pour animaux a sang froid | |
| DE2225548A1 (de) | Intravenoes vertraegliche staupe- und hepatitisvaccine | |
| DE864439C (de) | Verfahren zur Herstellung eines entgifteten Toxins aus der Siphonospora polymorpha von Brehmer | |
| DE2220053C3 (de) | Mittel zur aktiven und passiven Immunisierung gegen die toxischen Effekte von Infektionen durch Elastase bildende Bakterien und Verfahren zur Herstellung derselben | |
| DE424197C (de) | Verfahren zur Herstellung eines Naehrbodens fuer Influenzabazillen und zur Herstellung von Impfstoffen aus diesen | |
| DE1021128B (de) | Verfahren zur Herstellung eines Impfstoffes gegen die Rhinotracheitis der Rinder | |
| AT234902B (de) | Verfahren zur Herstellung einer Vaccine gegen Staupe | |
| DE2265620C2 (de) | Mittel zur passiven Immunisierung gegen die toxischen Effekte von Infektionen durch Elastase bildende Bakterien und Verfahren zur Herstellung desselben | |
| DE2517550C3 (de) | Verfahren zum Herstellen eines Lebend-Impfstoffs zum Immunisieren von fleischfressenden Tieren gegen Staupe | |
| DE2121237C3 (de) | Verwendung einer Zellinie zur Züchtung von Viren | |
| AT96830B (de) | Verfahren zur Herstellung eines Nährbodens für Influenzabazillen und zur Herstellung von Impfstoffen aus diesen. | |
| AT392480B (de) | Lebendvakzine gegen die svc (fruehjahrsviraemie der karpfen) und ihre herstellung |