DE112015003962B4 - 3-Hydroxypropionsäure erzeugende rekombinante Hefe und Verfahren zum Herstellen von 3-Hydroxypropionsäure unter Nutzung derselben - Google Patents
3-Hydroxypropionsäure erzeugende rekombinante Hefe und Verfahren zum Herstellen von 3-Hydroxypropionsäure unter Nutzung derselben Download PDFInfo
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- DE112015003962B4 DE112015003962B4 DE112015003962.7T DE112015003962T DE112015003962B4 DE 112015003962 B4 DE112015003962 B4 DE 112015003962B4 DE 112015003962 T DE112015003962 T DE 112015003962T DE 112015003962 B4 DE112015003962 B4 DE 112015003962B4
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- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/0103—3-Hydroxybutyrate dehydrogenase (1.1.1.30)
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- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01031—3-Hydroxyisobutyrate dehydrogenase (1.1.1.31)
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- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01059—3-Hydroxypropionate dehydrogenase (1.1.1.59)
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- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01061—4-Hydroxybutyrate dehydrogenase (1.1.1.61)
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- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01298—3-Hydroxypropionate dehydrogenase (NADP+) (1.1.1.298)
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- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/0101—Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
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- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01075—Malonyl CoA reductase (malonate semialdehyde-forming)(1.2.1.75)
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- C12Y208/00—Transferases transferring sulfur-containing groups (2.8)
- C12Y208/04—Transferases transferring sulfur-containing groups (2.8) transferring alkylthio groups (2.8.4)
- C12Y208/04001—Coenzyme-B sulfoethylthiotransferase (2.8.4.1)
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- C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
- C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
- C12Y604/01002—Acetyl-CoA carboxylase (6.4.1.2)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20140114505 | 2014-08-29 | ||
| KR10-2014-0114505 | 2014-08-29 | ||
| PCT/KR2015/009061 WO2016032279A1 (en) | 2014-08-29 | 2015-08-28 | Recombinant Yeast Producing 3-Hydroxypropionic Acid and Method for Producing 3-Hydroxypropionic Acid Using the Same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE112015003962T5 DE112015003962T5 (de) | 2017-08-03 |
| DE112015003962B4 true DE112015003962B4 (de) | 2024-12-19 |
Family
ID=55400077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE112015003962.7T Active DE112015003962B4 (de) | 2014-08-29 | 2015-08-28 | 3-Hydroxypropionsäure erzeugende rekombinante Hefe und Verfahren zum Herstellen von 3-Hydroxypropionsäure unter Nutzung derselben |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10704064B2 (https=) |
| JP (1) | JP6786477B2 (https=) |
| KR (1) | KR102281806B1 (https=) |
| CN (1) | CN107002019B (https=) |
| BR (1) | BR112017004069B1 (https=) |
| DE (1) | DE112015003962B4 (https=) |
| WO (1) | WO2016032279A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108728471B (zh) * | 2017-04-14 | 2020-01-31 | 中国科学院微生物研究所 | 产3-羟基丙酸的重组菌及其制备方法与应用 |
| CN108118004B (zh) * | 2017-12-15 | 2021-06-25 | 北京工商大学 | 一株喜仙人掌毕赤酵母在水果采后病害防治中的应用 |
| WO2019152754A1 (en) * | 2018-02-01 | 2019-08-08 | Invista North America S.A.R.L. | Methods and materials for the biosynthesis of beta hydroxy acids and derivatives and compounds related thereto |
| KR102140597B1 (ko) * | 2018-04-17 | 2020-08-03 | 에스케이이노베이션 주식회사 | 에탄올 생산 경로가 억제된 내산성 효모 및 이를 이용한 젖산의 제조방법 |
| KR102140596B1 (ko) * | 2018-04-17 | 2020-08-04 | 에스케이이노베이션 주식회사 | 유기산 내성 효모 유래 신규 프로모터 및 이를 이용한 목적유전자의 발현방법 |
| KR102736070B1 (ko) * | 2018-10-08 | 2024-12-02 | 에스케이이노베이션 주식회사 | 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법 |
| KR20220023757A (ko) * | 2019-04-24 | 2022-03-02 | 게노마티카 인코포레이티드 | 알데하이드 데하이드로게나아제 활성을 개선하기 위한 조작된 미생물 및 방법 |
| KR20210041903A (ko) | 2019-10-08 | 2021-04-16 | 에스케이이노베이션 주식회사 | 락테이트 대사 및 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법 |
| KR20210128742A (ko) * | 2020-04-17 | 2021-10-27 | 에스케이이노베이션 주식회사 | 글리세롤 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법 |
| KR20210158676A (ko) | 2020-06-24 | 2021-12-31 | 에스케이이노베이션 주식회사 | 젖산 생산능이 증가된 재조합 내산성 효모 |
| CN114480232B (zh) * | 2020-10-26 | 2024-02-02 | 北京化工大学 | 生产丙二酸的工程菌及其构建方法和应用 |
| US20220333118A1 (en) * | 2021-04-13 | 2022-10-20 | Debut Biotechnology, Inc. | Flavonoid and anthocyanin bioproduction using microorganism hosts |
| CN113563410A (zh) * | 2021-07-06 | 2021-10-29 | 南京瑞源生物技术有限公司 | 一种蛋白提取试剂配方 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7655451B2 (en) | 2002-01-18 | 2010-02-02 | Novozymes A/S | Alanine 2,3-aminomutase |
| US20100248233A1 (en) | 2007-07-23 | 2010-09-30 | Dsm Ip Assets B.V. | Acetyl-coa producing enzymes in yeast |
| US20120135481A1 (en) | 2010-11-22 | 2012-05-31 | Novozymes, Inc. | Compositions and methods for 3-hydroxypropionic acid production |
| US20130071893A1 (en) | 2009-09-27 | 2013-03-21 | Opx Biotechnologies, Inc. | Methods for producing 3-hydroxypropionic acid and other products |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5013448B2 (ja) | 2006-08-02 | 2012-08-29 | 帝人株式会社 | 出芽酵母の乳酸耐性又は生産性を向上させる多重遺伝子破壊の組み合わせ |
| KR101860442B1 (ko) * | 2011-06-27 | 2018-05-24 | 삼성전자주식회사 | 3-하이드록시프로피온산의 생산을 위한 유전자 조작 |
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2015
- 2015-08-28 US US15/506,981 patent/US10704064B2/en active Active
- 2015-08-28 KR KR1020150121623A patent/KR102281806B1/ko active Active
- 2015-08-28 CN CN201580052598.1A patent/CN107002019B/zh active Active
- 2015-08-28 JP JP2017510862A patent/JP6786477B2/ja active Active
- 2015-08-28 DE DE112015003962.7T patent/DE112015003962B4/de active Active
- 2015-08-28 WO PCT/KR2015/009061 patent/WO2016032279A1/en not_active Ceased
- 2015-08-28 BR BR112017004069-7A patent/BR112017004069B1/pt active IP Right Grant
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7655451B2 (en) | 2002-01-18 | 2010-02-02 | Novozymes A/S | Alanine 2,3-aminomutase |
| US20100248233A1 (en) | 2007-07-23 | 2010-09-30 | Dsm Ip Assets B.V. | Acetyl-coa producing enzymes in yeast |
| US20130071893A1 (en) | 2009-09-27 | 2013-03-21 | Opx Biotechnologies, Inc. | Methods for producing 3-hydroxypropionic acid and other products |
| US20120135481A1 (en) | 2010-11-22 | 2012-05-31 | Novozymes, Inc. | Compositions and methods for 3-hydroxypropionic acid production |
Non-Patent Citations (14)
| Title |
|---|
| 1. Chen, Y.; u. a.: Coupled incremental precursor and co-factor supply improves 3-hydroxypropionic acid production in Saccharomyces cerevisiae. Online: 4.2.2014. In: Metabolic Engineering, Vol. 22, S. 104-109. |
| Alber et al., J. Bacteriol. 188:8551-8559, 2006 |
| Berg et al., Science, 318:1782-1786, 2007 |
| Chen et al. beschriebenen Methode (2014, Metab. Eng. 22:104-109 |
| Diacovich et al. (2002, J. Biol. Chem. 277:31228-31236 |
| Hernandez et al., J. Biol. Chem. 275:33869-33875, 2000 |
| Hugler et al., J. Bacteriol. 184:2404-2410, 2002 |
| Kockelkorn and Fuchs, J. Bacteriol. 191:6352-6362, 2009 |
| Kozak et al. (2014, Metab. Eng. 21:46-59 |
| Kröger et al. (2011, Anal. Biochem. 411:100-105 |
| Stojiljkovic et al., J. Bacteriol. 177:1357-1366, 1995 |
| Wei et al., Nat. Commun. 4:2580, 2013 |
| Y. Chen et al., Metabolic Engineering, 22:104-109, 2014 |
| Yao et al., Appl. Biochem. Biotechnol. 160:694-703, 2010 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017525372A (ja) | 2017-09-07 |
| KR20170025315A (ko) | 2017-03-08 |
| KR102281806B1 (ko) | 2021-07-27 |
| CN107002019B (zh) | 2021-11-23 |
| CN107002019A (zh) | 2017-08-01 |
| DE112015003962T5 (de) | 2017-08-03 |
| JP6786477B2 (ja) | 2020-11-18 |
| BR112017004069B1 (pt) | 2024-02-06 |
| BR112017004069A2 (pt) | 2018-01-23 |
| WO2016032279A1 (en) | 2016-03-03 |
| WO2016032279A9 (en) | 2016-04-28 |
| US10704064B2 (en) | 2020-07-07 |
| US20170240932A1 (en) | 2017-08-24 |
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