BR112017004069B1 - Levedura recombinante produzindo ácido 3-hidroxipropiônico e método para produzir ácido 3-hidroxipropiônico usando o mesmo - Google Patents

Levedura recombinante produzindo ácido 3-hidroxipropiônico e método para produzir ácido 3-hidroxipropiônico usando o mesmo Download PDF

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BR112017004069B1
BR112017004069B1 BR112017004069-7A BR112017004069A BR112017004069B1 BR 112017004069 B1 BR112017004069 B1 BR 112017004069B1 BR 112017004069 A BR112017004069 A BR 112017004069A BR 112017004069 B1 BR112017004069 B1 BR 112017004069B1
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Brazil
Prior art keywords
seq
coa
yeast
acetyl
glucose
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BR112017004069-7A
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English (en)
Portuguese (pt)
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BR112017004069A2 (pt
Inventor
Joong Min Park
Jae Yeon Park
Woo Chan Park
Sang Min Lee
Young Bin Seo
Merja Oja
Outi Koivistoinen
Andrew Conley
Marja Ilmén
Laura Ruohonen
Paula Jouhten
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Sk Innovation Co., Ltd
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Publication of BR112017004069A2 publication Critical patent/BR112017004069A2/pt
Publication of BR112017004069B1 publication Critical patent/BR112017004069B1/pt

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12P7/00—Preparation of oxygen-containing organic compounds
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    • C12P7/42—Hydroxy-carboxylic acids
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    • C12N9/0004—Oxidoreductases (1.)
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    • C12N9/93—Ligases (6)
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    • C12Y101/0103—3-Hydroxybutyrate dehydrogenase (1.1.1.30)
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    • C12Y101/01031—3-Hydroxyisobutyrate dehydrogenase (1.1.1.31)
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01059—3-Hydroxypropionate dehydrogenase (1.1.1.59)
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01061—4-Hydroxybutyrate dehydrogenase (1.1.1.61)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01298—3-Hydroxypropionate dehydrogenase (NADP+) (1.1.1.298)
    • C—CHEMISTRY; METALLURGY
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    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0101—Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
    • C—CHEMISTRY; METALLURGY
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    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01075—Malonyl CoA reductase (malonate semialdehyde-forming)(1.2.1.75)
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    • C12Y208/00—Transferases transferring sulfur-containing groups (2.8)
    • C12Y208/04—Transferases transferring sulfur-containing groups (2.8) transferring alkylthio groups (2.8.4)
    • C12Y208/04001—Coenzyme-B sulfoethylthiotransferase (2.8.4.1)
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    • C12Y—ENZYMES
    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01002—Acetyl-CoA carboxylase (6.4.1.2)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
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  • Molecular Biology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR112017004069-7A 2014-08-29 2015-08-28 Levedura recombinante produzindo ácido 3-hidroxipropiônico e método para produzir ácido 3-hidroxipropiônico usando o mesmo BR112017004069B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20140114505 2014-08-29
KR10-2014-0114505 2014-08-29
PCT/KR2015/009061 WO2016032279A1 (en) 2014-08-29 2015-08-28 Recombinant Yeast Producing 3-Hydroxypropionic Acid and Method for Producing 3-Hydroxypropionic Acid Using the Same

Publications (2)

Publication Number Publication Date
BR112017004069A2 BR112017004069A2 (pt) 2018-01-23
BR112017004069B1 true BR112017004069B1 (pt) 2024-02-06

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ID=55400077

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BR112017004069-7A BR112017004069B1 (pt) 2014-08-29 2015-08-28 Levedura recombinante produzindo ácido 3-hidroxipropiônico e método para produzir ácido 3-hidroxipropiônico usando o mesmo

Country Status (7)

Country Link
US (1) US10704064B2 (https=)
JP (1) JP6786477B2 (https=)
KR (1) KR102281806B1 (https=)
CN (1) CN107002019B (https=)
BR (1) BR112017004069B1 (https=)
DE (1) DE112015003962B4 (https=)
WO (1) WO2016032279A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108728471B (zh) * 2017-04-14 2020-01-31 中国科学院微生物研究所 产3-羟基丙酸的重组菌及其制备方法与应用
CN108118004B (zh) * 2017-12-15 2021-06-25 北京工商大学 一株喜仙人掌毕赤酵母在水果采后病害防治中的应用
WO2019152754A1 (en) * 2018-02-01 2019-08-08 Invista North America S.A.R.L. Methods and materials for the biosynthesis of beta hydroxy acids and derivatives and compounds related thereto
KR102140597B1 (ko) * 2018-04-17 2020-08-03 에스케이이노베이션 주식회사 에탄올 생산 경로가 억제된 내산성 효모 및 이를 이용한 젖산의 제조방법
KR102140596B1 (ko) * 2018-04-17 2020-08-04 에스케이이노베이션 주식회사 유기산 내성 효모 유래 신규 프로모터 및 이를 이용한 목적유전자의 발현방법
KR102736070B1 (ko) * 2018-10-08 2024-12-02 에스케이이노베이션 주식회사 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20220023757A (ko) * 2019-04-24 2022-03-02 게노마티카 인코포레이티드 알데하이드 데하이드로게나아제 활성을 개선하기 위한 조작된 미생물 및 방법
KR20210041903A (ko) 2019-10-08 2021-04-16 에스케이이노베이션 주식회사 락테이트 대사 및 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210128742A (ko) * 2020-04-17 2021-10-27 에스케이이노베이션 주식회사 글리세롤 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210158676A (ko) 2020-06-24 2021-12-31 에스케이이노베이션 주식회사 젖산 생산능이 증가된 재조합 내산성 효모
CN114480232B (zh) * 2020-10-26 2024-02-02 北京化工大学 生产丙二酸的工程菌及其构建方法和应用
US20220333118A1 (en) * 2021-04-13 2022-10-20 Debut Biotechnology, Inc. Flavonoid and anthocyanin bioproduction using microorganism hosts
CN113563410A (zh) * 2021-07-06 2021-10-29 南京瑞源生物技术有限公司 一种蛋白提取试剂配方

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2329778T3 (es) 2002-01-18 2009-12-01 Novozymes A/S 2,3-aminomutasa de alanina.
JP5013448B2 (ja) 2006-08-02 2012-08-29 帝人株式会社 出芽酵母の乳酸耐性又は生産性を向上させる多重遺伝子破壊の組み合わせ
US20100248233A1 (en) 2007-07-23 2010-09-30 Dsm Ip Assets B.V. Acetyl-coa producing enzymes in yeast
GB2487866A (en) 2009-09-27 2012-08-08 Opx Biotechnologies Inc Method for producing 3-Hydroxypropionic acid and other products
CN107828671B (zh) * 2010-11-22 2022-03-08 卡吉尔公司 用于生产3-羟基丙酸的组合物和方法
KR101860442B1 (ko) * 2011-06-27 2018-05-24 삼성전자주식회사 3-하이드록시프로피온산의 생산을 위한 유전자 조작

Also Published As

Publication number Publication date
JP2017525372A (ja) 2017-09-07
KR20170025315A (ko) 2017-03-08
KR102281806B1 (ko) 2021-07-27
CN107002019B (zh) 2021-11-23
CN107002019A (zh) 2017-08-01
DE112015003962T5 (de) 2017-08-03
JP6786477B2 (ja) 2020-11-18
BR112017004069A2 (pt) 2018-01-23
DE112015003962B4 (de) 2024-12-19
WO2016032279A1 (en) 2016-03-03
WO2016032279A9 (en) 2016-04-28
US10704064B2 (en) 2020-07-07
US20170240932A1 (en) 2017-08-24

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