DE102005062634A1 - Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung - Google Patents

Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung Download PDF

Info

Publication number
DE102005062634A1
DE102005062634A1 DE102005062634A DE102005062634A DE102005062634A1 DE 102005062634 A1 DE102005062634 A1 DE 102005062634A1 DE 102005062634 A DE102005062634 A DE 102005062634A DE 102005062634 A DE102005062634 A DE 102005062634A DE 102005062634 A1 DE102005062634 A1 DE 102005062634A1
Authority
DE
Germany
Prior art keywords
blood
irradiation
preparations
exposure
bag
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102005062634A
Other languages
German (de)
English (en)
Other versions
DE102005062634A9 (de
Inventor
Harald Dr. Mohr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Blutspendedienst der Landsverbande des Deutschen Roten Kreuses
Original Assignee
Blutspendedienst der Landsverbande des Deutschen Roten Kreuses
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blutspendedienst der Landsverbande des Deutschen Roten Kreuses filed Critical Blutspendedienst der Landsverbande des Deutschen Roten Kreuses
Priority to DE102005062634A priority Critical patent/DE102005062634A1/de
Priority to RU2008129480/14A priority patent/RU2466742C2/ru
Priority to JP2008546124A priority patent/JP5232008B2/ja
Priority to HK09101974.9A priority patent/HK1121406B/xx
Priority to ES10001518T priority patent/ES2369059T3/es
Priority to KR1020087017172A priority patent/KR101499735B1/ko
Priority to CN2006800479151A priority patent/CN101340930B/zh
Priority to DE502006006204T priority patent/DE502006006204D1/de
Priority to PT10001518T priority patent/PT2198886E/pt
Priority to PT06840887T priority patent/PT1962905E/pt
Priority to PL06840887T priority patent/PL1962905T3/pl
Priority to CA2632558A priority patent/CA2632558C/en
Priority to US11/643,728 priority patent/US8164073B2/en
Priority to DK06840887.1T priority patent/DK1962905T3/da
Priority to AT10001518T priority patent/ATE514432T1/de
Priority to EP10001518A priority patent/EP2198886B1/de
Priority to SI200631112T priority patent/SI2198886T1/sl
Priority to PL10001518T priority patent/PL2198886T3/pl
Priority to SI200630632T priority patent/SI1962905T1/sl
Priority to PCT/DE2006/002307 priority patent/WO2007076832A1/de
Priority to HK09101975.8A priority patent/HK1121407B/xx
Priority to AU2006332291A priority patent/AU2006332291B2/en
Priority to AT06840887T priority patent/ATE457739T1/de
Priority to DK10001518.9T priority patent/DK2198886T3/da
Priority to EP06840887A priority patent/EP1962905B1/de
Priority to ES06840887T priority patent/ES2341368T3/es
Publication of DE102005062634A1 publication Critical patent/DE102005062634A1/de
Publication of DE102005062634A9 publication Critical patent/DE102005062634A9/de
Priority to HK10110638.5A priority patent/HK1144249B/xx
Priority to US13/419,778 priority patent/US8525128B2/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/10—Ultraviolet [UV] radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
DE102005062634A 2005-12-23 2005-12-23 Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung Withdrawn DE102005062634A1 (de)

Priority Applications (28)

Application Number Priority Date Filing Date Title
DE102005062634A DE102005062634A1 (de) 2005-12-23 2005-12-23 Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung
SI200631112T SI2198886T1 (sl) 2005-12-23 2006-12-21 Postopek za inaktiviranje patogenov v krvi darovalca krvni plazmi ali koncentratih eritrocitov v spremenljivih embalažah v gibanju
EP10001518A EP2198886B1 (de) 2005-12-23 2006-12-21 Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung
HK09101974.9A HK1121406B (en) 2005-12-23 2006-12-21 Method for the inactivation of pathogens in donor blood, blood plasma or erythrocyte concentrations in flexible containers using agitation
ES10001518T ES2369059T3 (es) 2005-12-23 2006-12-21 Procedimiento para la inactivación de patógenos en sangre de donantes, en plasma sanguíneo o en concentrados de eritrocitos en recipientes flexibles bajo agitación.
KR1020087017172A KR101499735B1 (ko) 2005-12-23 2006-12-21 교반을 이용한 유연성 용기 내의 헌혈자의 혈액, 혈장 또는적혈구 농축액 안의 병원체의 불활성화 방법
CN2006800479151A CN101340930B (zh) 2005-12-23 2006-12-21 在柔性容器中运动下灭活供体血液、血浆或红细胞浓缩物中病原体的方法
DE502006006204T DE502006006204D1 (de) 2005-12-23 2006-12-21 Verfahren zur inaktivierung von pathogenen in spenderblut, blutplasma oder erythrozytenkonzentraten in flexiblen behältnissen unter bewegung
PT10001518T PT2198886E (pt) 2005-12-23 2006-12-21 Processo para a inactivação de patogéneos em sangue de dadores, plasma sanguíneo ou concentrados de eritrócitos em recipientes flexíveis sob movimentação
PT06840887T PT1962905E (pt) 2005-12-23 2006-12-21 Processo para a inactivação de patogéneos em sangue de dadores, plasma sanguíneo ou concentrados de eritrócitos em recipientes flexíveis por agitação
PL06840887T PL1962905T3 (pl) 2005-12-23 2006-12-21 Sposób inaktywacji czynników chorobotwórczych we krwi dawcy, osoczu krwi albo w koncentratach erytrocytów w elastycznych pojemnikach z zastosowaniem mieszania
CA2632558A CA2632558C (en) 2005-12-23 2006-12-21 Method for the inactivation of pathogens in donor blood, blood plasma or erythrocyte concentrations in flexible containers using agitation
US11/643,728 US8164073B2 (en) 2005-12-23 2006-12-21 Method for the inactivation of pathogens in donor blood, blood plasma or erythrocyte concentrates in flexible containers under agitation
DK06840887.1T DK1962905T3 (da) 2005-12-23 2006-12-21 Fremgangsmåde til inaktivering af patogener i donorblod, blodplasma eller erythrocytkoncentrater i fleksible beholdere ved agitation
AT10001518T ATE514432T1 (de) 2005-12-23 2006-12-21 Verfahren zur inaktivierung von pathogenen in spenderblut, blutplasma oder erythrozytenkonzentraten in flexiblen behältnissen unter bewegung
RU2008129480/14A RU2466742C2 (ru) 2005-12-23 2006-12-21 Способ инактивирования патогенов в донорской крови, плазме крови или концентратах эритроцитов в гибких контейнерах с помощью встряхивания
AU2006332291A AU2006332291B2 (en) 2005-12-23 2006-12-21 Method for the inactivation of pathogens in donor blood, blood plasma or erythrocyte concentrations in flexible containers using agitation
DK10001518.9T DK2198886T3 (da) 2005-12-23 2006-12-21 Fremgangsmåde til deaktivering af patogener i donorblod, blodplasma eller erythrocytkoncentrater i fleksible beholdere i bevægelse
SI200630632T SI1962905T1 (sl) 2005-12-23 2006-12-21 Postopek za inaktivacijo patogenov v darovani krvi krvni plazmi ali eritrocitni koncentraciji v fleksibilnih posodah z agitacijo
PCT/DE2006/002307 WO2007076832A1 (de) 2005-12-23 2006-12-21 Verfahren zur inaktivierung von pathogenen in spenderblut, blutplasma oder erythrozytenkonzentraten in flexiblen behältnissen unter bewegung
HK09101975.8A HK1121407B (en) 2005-12-23 2006-12-21 Method for the inactivation of pathogens in donor blood, blood plasma or erythrocyte concentrations in flexible containers under agitation
JP2008546124A JP5232008B2 (ja) 2005-12-23 2006-12-21 給血者の血、血漿、または、赤血球濃縮物中の病原体を柔軟な容器中で動かしながら不活化するための方法
AT06840887T ATE457739T1 (de) 2005-12-23 2006-12-21 Verfahren zur inaktivierung von pathogenen in spenderblut, blutplasma oder erythrozytenkonzentraten in flexiblen behältnissen unter bewegung
PL10001518T PL2198886T3 (pl) 2005-12-23 2006-12-21 Sposób inaktywacji czynników chorobotwórczych we krwi dawcy, osoczu krwi albo w koncentratach erytrocytów w elastycznych pojemnikach pod wpływem ruchu
EP06840887A EP1962905B1 (de) 2005-12-23 2006-12-21 Verfahren zur inaktivierung von pathogenen in spenderblut, blutplasma oder erythrozytenkonzentraten in flexiblen behältnissen unter bewegung
ES06840887T ES2341368T3 (es) 2005-12-23 2006-12-21 Procedimiento para la inactivacion de patogenos en sangre de donantes, en plasma sanguineo o en concentrados de eritrocitos en recipientes flexibles bajo agitacion.
HK10110638.5A HK1144249B (en) 2005-12-23 2010-11-16 Method for inactivating pathogens in donor blood, blood plasma or erythrocyte concentrates in flexible containers in motion
US13/419,778 US8525128B2 (en) 2005-12-23 2012-03-14 Method for the inactivation of pathogens in donor blood, blood plasma or erythrocyte concentrates in flexible containers under agitation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005062634A DE102005062634A1 (de) 2005-12-23 2005-12-23 Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung

Publications (2)

Publication Number Publication Date
DE102005062634A1 true DE102005062634A1 (de) 2007-06-28
DE102005062634A9 DE102005062634A9 (de) 2007-10-11

Family

ID=38043033

Family Applications (2)

Application Number Title Priority Date Filing Date
DE102005062634A Withdrawn DE102005062634A1 (de) 2005-12-23 2005-12-23 Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung
DE502006006204T Active DE502006006204D1 (de) 2005-12-23 2006-12-21 Verfahren zur inaktivierung von pathogenen in spenderblut, blutplasma oder erythrozytenkonzentraten in flexiblen behältnissen unter bewegung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE502006006204T Active DE502006006204D1 (de) 2005-12-23 2006-12-21 Verfahren zur inaktivierung von pathogenen in spenderblut, blutplasma oder erythrozytenkonzentraten in flexiblen behältnissen unter bewegung

Country Status (16)

Country Link
US (2) US8164073B2 (https=)
EP (2) EP1962905B1 (https=)
JP (1) JP5232008B2 (https=)
KR (1) KR101499735B1 (https=)
CN (1) CN101340930B (https=)
AT (2) ATE514432T1 (https=)
AU (1) AU2006332291B2 (https=)
CA (1) CA2632558C (https=)
DE (2) DE102005062634A1 (https=)
DK (2) DK1962905T3 (https=)
ES (2) ES2341368T3 (https=)
PL (2) PL2198886T3 (https=)
PT (2) PT1962905E (https=)
RU (1) RU2466742C2 (https=)
SI (2) SI2198886T1 (https=)
WO (1) WO2007076832A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115350296A (zh) * 2022-08-30 2022-11-18 南京双威生物医学科技有限公司 基于核黄素光化学法的血液病原体灭活处理系统
WO2023006151A1 (de) * 2021-07-27 2023-02-02 Blutspendedienst der Landesverbände des DRK in Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen g.G.m.b.H. Additivlösung für erythrozytenkonzentrate

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005062410A1 (de) 2005-12-23 2007-08-09 Forschungsgemeinschaft Der Drk-Blutspendedienste E.V. Verfahren zur Bestrahlung von Thrombozytenkonzentraten in flexiblen Behältnissen mit ultraviolettem Licht
DE102005062634A1 (de) 2005-12-23 2007-06-28 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung
EP1902740A1 (en) 2006-09-19 2008-03-26 Maco Pharma S.A. Blood bag system and process for the inactivation of pathogens in platelet concentrates by use of the blood bag system
EP2008669A1 (en) 2007-06-22 2008-12-31 Maco Pharma S.A. Irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid and process
EP2459248B1 (en) * 2009-06-02 2019-05-22 biolitec Unternehmensbeteiligungs II AG A novel method for microbial depletion in human blood and blood products using antimicrobial photodynamic therapy
GB201006753D0 (en) 2010-04-22 2010-06-09 Biotest Ag Process for preparing an immunolobulin composition
US12279610B2 (en) 2011-03-15 2025-04-22 Paragonix Technonogies, Inc. System for hypothermic transport of samples
US8883409B1 (en) * 2013-12-08 2014-11-11 Hemalux LLC Method of reducing pathogens in whole blood by illuminating with ultraviolet light under low oxygen conditions
US20210400952A1 (en) 2017-06-07 2021-12-30 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
CN107833751A (zh) * 2017-10-27 2018-03-23 吉林化工学院 一种复合膜电极制备方法及光电性质检测方法
US12558463B2 (en) 2019-03-11 2026-02-24 ABC Med Tech Corp. Portable centrifuge device and method of use
US11964092B2 (en) 2019-03-11 2024-04-23 ABC Med Tech Corp. Portable centrifuge and method of use
EP3982725A4 (en) * 2019-06-11 2023-07-19 Paragonix Technologies Inc. ORGAN TRANSPORT CONTAINER WITH ANTIVIRAL THERAPY
EP4034303B1 (en) * 2019-09-24 2024-03-20 ABC Med Tech Corp. Centrifuge device and method of use
US11632951B2 (en) 2020-01-31 2023-04-25 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
US20210338860A1 (en) 2020-05-01 2021-11-04 Uv Innovators, Llc Ultraviolet (uv) light emission device employing visible light for operation guidance, and related methods of use, particularly suited for decontamination
FR3117872A1 (fr) * 2020-12-21 2022-06-24 Maco Pharma Procédé et système pour produire des cellules mononucléées apoptotiques
JP7776724B2 (ja) 2021-04-27 2025-11-27 日亜化学工業株式会社 カルシウムチャネル及び／又はカルシウムポンプの発現を誘導する方法及び培養装置
US12485064B2 (en) 2023-08-25 2025-12-02 Paragonix Technologies, Inc. Systems and methods for measuring oxygen concentration for lung preservation
US20250248390A1 (en) 2024-02-02 2025-08-07 Paragonix Technologies, Inc. System for perfusion of an organ
USD1087382S1 (en) 2025-01-30 2025-08-05 Paragonix Technologies, Inc. Device for transporting a biological sample

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469227A (en) 1983-08-17 1984-09-04 Clifford Faust Package for cryogenically frozen liquids
US4586928A (en) 1984-10-09 1986-05-06 Miles Laboratories, Inc. Pivoting frangible valve for plastic bags
US4952812A (en) 1986-08-26 1990-08-28 Baxter International Inc. Irradiation of blood products
US4878891A (en) 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
GB8807380D0 (en) * 1988-03-29 1988-05-05 Gunn A Blood processing apparatus
US5661126A (en) * 1989-01-19 1997-08-26 The General Hospital Corporation Use of mullerian inhibiting substance for treating certain tumors and for modulating class I major histocompatibility antigen expression
US4952818A (en) 1989-05-17 1990-08-28 International Business Machines Corporation Transmission line driver circuits
JP3051997B2 (ja) * 1990-12-20 2000-06-12 バクスター、インターナショナル、インコーポレイテッド 液体中の汚染物を根絶するシステム及び方法
JPH05131018A (ja) 1991-11-11 1993-05-28 Terumo Corp バツグ連結体およびその製造方法
US6420570B1 (en) * 1993-06-28 2002-07-16 Cerus Corporation Psoralen compounds
US5625079A (en) 1993-06-28 1997-04-29 Cerus Corporation Synthesizing psoralen compounds useful as intermediates
JP3677287B2 (ja) 1993-11-10 2005-07-27 セラス コーポレーション 光活性化のための装置および方法
DK0840624T3 (da) 1995-07-14 2007-11-05 Caf Dcf Cvba Scrl Apparat til inaktivering af viruskontaminanter i blodprodukter
DE29801590U1 (de) 1998-01-30 1998-04-16 Maco Pharma Int Gmbh Blutbeutelsystem zur Virusinaktivierung von Blut, Blutkomponenten und Plasma
DE19831768A1 (de) * 1998-07-15 2000-02-17 Paa Lab Gmbh Vorrichtung zur Bestrahlung einer Flüssigkeit
EP1002512A3 (en) 1998-11-19 2001-01-24 Bracco International B.V. Flexible container for the containment and delivery of fluids
US7068361B2 (en) 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US7445756B2 (en) 1999-06-03 2008-11-04 Fenwal, Inc. Fluid processing sets and organizers for the same
US7094378B1 (en) 2000-06-15 2006-08-22 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
US6268120B1 (en) 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
US6596230B1 (en) * 2000-01-28 2003-07-22 Baxter International Inc. Device and method for pathogen inactivation of therapeutic fluids with sterilizing radiation
US6576201B1 (en) * 2000-01-28 2003-06-10 Baxter International Inc. Device and method for pathogen inactivation of therapeutic fluids with sterilizing radiation
WO2002026270A2 (en) 2000-09-27 2002-04-04 Gambro, Inc. Inactivation of contaminants using photosensitizers and pulsed light
US20020138066A1 (en) 2001-03-23 2002-09-26 Gambro, Inc. Multiple compartment bag with openable closure assembly
WO2002092806A1 (en) * 2001-05-15 2002-11-21 V.I. Technologies, Inc. Apparatus for the inactivation of pathogens in protein-containingfluids
US20030064001A1 (en) 2001-05-17 2003-04-03 Fries William M. System for the decontamination of fluid products using light
US20030228564A1 (en) 2001-05-30 2003-12-11 Edrich Richard Alan Nitric oxide in a pathogen inactivation process
WO2003026724A1 (en) 2001-09-27 2003-04-03 Gambro, Inc. Radio frequency or electromagnetic information systems and methods for use in extracorporeal blood processing
DE10152159A1 (de) 2001-10-25 2003-05-15 Aventis Behring Gmbh Verfahren zur proteinschonenden Reinigung von kontaminierten biologischen Flüssigkeiten
WO2003063915A1 (en) 2002-02-01 2003-08-07 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
MXPA04010027A (es) 2002-04-12 2005-07-01 Throwleigh Technologies L L C Metodos y aparatos para descontaminar fluidos.
EP1501555B1 (en) 2002-04-26 2007-02-21 Gambro, Inc., Apparatus for irradiating and mixing fluids in containers
JP4154191B2 (ja) * 2002-08-28 2008-09-24 テルモ株式会社 光照射装置および光照射方法
US7207964B2 (en) 2003-03-17 2007-04-24 Hemavation, Llc Apparatus and method for down-regulating immune system mediators in blood
US20080177217A1 (en) * 2004-05-14 2008-07-24 Hans-Dietrich Polaschegg Taurolidine Formulations and Delivery: Therapeutic Treatments and Antimicrobial Protection Against Bacterial Biofilm Formation
US8296071B2 (en) * 2004-03-15 2012-10-23 Terumo Bct Biotechnologies, Llc Methods for uniformly treating biological samples with electromagnetic radiation
FR2887335B1 (fr) 2005-06-21 2007-08-10 Maco Pharma Sa Procede pour la determination d'une contamination pathogene dans un fluide contenant des plaquettes sanguines
DE102005062634A1 (de) 2005-12-23 2007-06-28 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung
DE102005062410A1 (de) 2005-12-23 2007-08-09 Forschungsgemeinschaft Der Drk-Blutspendedienste E.V. Verfahren zur Bestrahlung von Thrombozytenkonzentraten in flexiblen Behältnissen mit ultraviolettem Licht
EP1902740A1 (en) 2006-09-19 2008-03-26 Maco Pharma S.A. Blood bag system and process for the inactivation of pathogens in platelet concentrates by use of the blood bag system
EP2008669A1 (en) 2007-06-22 2008-12-31 Maco Pharma S.A. Irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid and process

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023006151A1 (de) * 2021-07-27 2023-02-02 Blutspendedienst der Landesverbände des DRK in Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen g.G.m.b.H. Additivlösung für erythrozytenkonzentrate
DE102021119408A1 (de) 2021-07-27 2023-02-02 Blutspendedienst der Landesverbände des DRK in Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen g.G.m.b.H. Additivlösung für Erythrozytenkonzentrate
CN115350296A (zh) * 2022-08-30 2022-11-18 南京双威生物医学科技有限公司 基于核黄素光化学法的血液病原体灭活处理系统

Also Published As

Publication number Publication date
JP2009520703A (ja) 2009-05-28
EP1962905B1 (de) 2010-02-17
CA2632558A1 (en) 2007-07-12
US20070164233A1 (en) 2007-07-19
ES2369059T3 (es) 2011-11-24
US8525128B2 (en) 2013-09-03
PL1962905T3 (pl) 2010-08-31
ES2341368T3 (es) 2010-06-18
RU2008129480A (ru) 2010-01-27
AU2006332291A1 (en) 2007-07-12
DK2198886T3 (da) 2011-10-10
KR101499735B1 (ko) 2015-03-06
RU2466742C2 (ru) 2012-11-20
JP5232008B2 (ja) 2013-07-10
EP2198886B1 (de) 2011-06-29
WO2007076832A1 (de) 2007-07-12
EP1962905A1 (de) 2008-09-03
KR20080081038A (ko) 2008-09-05
SI2198886T1 (sl) 2011-11-30
EP2198886A1 (de) 2010-06-23
HK1121406A1 (zh) 2009-04-24
DE502006006204D1 (de) 2010-04-01
HK1121407A1 (en) 2009-04-24
HK1144249A1 (en) 2011-02-11
CN101340930B (zh) 2012-09-05
PT1962905E (pt) 2010-05-14
PL2198886T3 (pl) 2012-01-31
AU2006332291B2 (en) 2012-02-23
CN101340930A (zh) 2009-01-07
ATE457739T1 (de) 2010-03-15
SI1962905T1 (sl) 2010-06-30
DK1962905T3 (da) 2010-06-07
CA2632558C (en) 2013-06-11
DE102005062634A9 (de) 2007-10-11
US20120228517A1 (en) 2012-09-13
PT2198886E (pt) 2011-09-28
ATE514432T1 (de) 2011-07-15
US8164073B2 (en) 2012-04-24

Similar Documents

Publication Publication Date Title
DE102005062634A1 (de) Verfahren zur Inaktivierung von Pathogenen in Spenderblut, Blutplasma oder Erythrozytenkonzentraten in flexiblen Behältnissen unter Bewegung
DE60124095T2 (de) Verfahren zur inaktivierung von mikroorganismen unter verwendung von photosensibilisatoren
DE69637181T2 (de) Vorrichtung zur inaktivierung von viralen verunreinigungen in blutprodukten
DE69821002T2 (de) Verbesserte lager- und haltbarkeit von blutprodukten
DE3855220T2 (de) Methode zur beseitigung von infektionserregern in geweben
EP1968652B1 (de) Verfahren zur bestrahlung von thrombozytenkonzentraten in flexiblen behältnissen mit ultraviolettem licht
DE69328685T2 (de) Verfahren zur inaktivierung von bakterien in blutpräparaten mit hilfe von methoxypsoralen
DE69434445T2 (de) Verfahren zur sterilisation biologischer zusammensetzungen und das dabei erhaltene produkt
DE3930510A1 (de) Verfahren zur inaktivierung von viren in blut und blutprodukten
WO2005003340A2 (de) Verfahren zur inaktivierung von mikroorganismen
DE2742588B2 (de) Verfahren zur Sterilisation eines Dialysators mit semipermeabler Membran
DE60017243T2 (de) Verfahren zur inaktivierung von pathogenen mittels breitspektrum-pulslicht
DE69430219T2 (de) Apparatur und Verfahren zur Inaktivierung von viralen Verunreinigungen in Körperflüssigkeit
DE69627202T2 (de) Behandlung von roten blutzellen zur inaktivierung von virien durch verwendung von pathalocyanine und rotlicht
EP4344397B1 (de) Verfahren zur herstellung von erythrozytenkonzentraten
EP1307241B1 (de) Photodynamische behandlung und uv-b- bestrahlung einer thrombozyten-suspension
EP2190485A1 (de) Verfahren zur reduktion der viren- und mikroorganismen-belastung feststoffhaltiger biologischer extrakte und nach dem verfahren hergestellte extrakte
DE69813634T2 (de) Entfernung von desinfektionsfarben
DE69911438T2 (de) Schnelle tieftemperatur-drucksterilisation und impfstoffherstellung
DD263449A1 (de) Verfahren zur oekonomischen und schonenden hygienisierung und auskeimungshemmung von materialien und bioprodukten
DE3438946A1 (de) Zubereitung zur erhoehung der strukturellen resistenz von nutz- und zierpflanzen und verwendung derselben
HK1121406B (en) Method for the inactivation of pathogens in donor blood, blood plasma or erythrocyte concentrations in flexible containers using agitation

Legal Events

Date Code Title Description
8197 Reprint of an erroneous patent document
R005 Application deemed withdrawn due to failure to request examination

Effective date: 20121225