DD298205A5 - Verfahren zum herstellen von langzeitwirkenden arzneimittelzubereitungen - Google Patents

Verfahren zum herstellen von langzeitwirkenden arzneimittelzubereitungen Download PDF

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Publication number
DD298205A5
DD298205A5 DD90344294A DD34429490A DD298205A5 DD 298205 A5 DD298205 A5 DD 298205A5 DD 90344294 A DD90344294 A DD 90344294A DD 34429490 A DD34429490 A DD 34429490A DD 298205 A5 DD298205 A5 DD 298205A5
Authority
DD
German Democratic Republic
Prior art keywords
drug
granules
long
copolymer
acting
Prior art date
Application number
DD90344294A
Other languages
German (de)
English (en)
Inventor
Tadayoshi Ohmura
Muneo Fukui
Hiroshi Sugiura
Satoru Yoneya
Toshiharu Hosono
Atsushi Kajiyama
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������@�������������@��Kk���Kk�� filed Critical �������@�������������@��Kk���Kk��
Publication of DD298205A5 publication Critical patent/DD298205A5/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DD90344294A 1989-03-10 1990-03-12 Verfahren zum herstellen von langzeitwirkenden arzneimittelzubereitungen DD298205A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5868489 1989-03-10

Publications (1)

Publication Number Publication Date
DD298205A5 true DD298205A5 (de) 1992-02-13

Family

ID=13091382

Family Applications (2)

Application Number Title Priority Date Filing Date
DD90338614A DD292374A5 (de) 1989-03-10 1990-03-12 Verfahren zum herstellen von ueberzugsmaterialien zur steuerung der arzneimittelfreisetzung bei langzeitwirkenden zubereitungen
DD90344294A DD298205A5 (de) 1989-03-10 1990-03-12 Verfahren zum herstellen von langzeitwirkenden arzneimittelzubereitungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DD90338614A DD292374A5 (de) 1989-03-10 1990-03-12 Verfahren zum herstellen von ueberzugsmaterialien zur steuerung der arzneimittelfreisetzung bei langzeitwirkenden zubereitungen

Country Status (19)

Country Link
US (1) US5028664A (da)
EP (1) EP0386967B1 (da)
JP (1) JPH037238A (da)
KR (1) KR0140985B1 (da)
CN (1) CN1045524A (da)
AT (1) ATE124864T1 (da)
AU (1) AU623233B2 (da)
CA (1) CA2011919A1 (da)
DD (2) DD292374A5 (da)
DE (1) DE69020758T2 (da)
DK (1) DK0386967T3 (da)
ES (1) ES2077023T3 (da)
FI (1) FI97690C (da)
GR (1) GR3017645T3 (da)
HU (1) HU204201B (da)
IE (1) IE68520B1 (da)
NO (1) NO301578B1 (da)
NZ (1) NZ232836A (da)
PT (1) PT93384B (da)

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GB2253346A (en) * 1991-02-22 1992-09-09 John Rhodes Delayed release oral dosage forms for treatment of intestinal disorders
GB9200607D0 (en) * 1992-01-13 1992-03-11 Ethical Pharma Ltd Pharmaceutical compositions containing nifedipine and process for the preparation thereof
US20030170290A1 (en) * 1993-06-16 2003-09-11 Shug Austin L. Delayed release carnitine
WO1995005168A1 (en) * 1993-08-19 1995-02-23 Shug Austin L Delayed release carnitine
DE9414066U1 (de) * 1994-08-31 1994-11-03 Roehm Gmbh Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform
NZ270078A (en) * 1994-12-06 1998-05-27 Bernard Charles Sherman Diltiazem hydrochloride formulation comprising beads with immediate, intermediate, and delayed release dissolution profiles
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
ATE240734T1 (de) * 1995-07-26 2003-06-15 Kyowa Hakko Kogyo Kk Zubereitung von xanthinderivaten als feste dispersion
US6162463A (en) * 1997-05-01 2000-12-19 Dov Pharmaceutical Inc Extended release formulation of diltiazem hydrochloride
US6342611B1 (en) * 1997-10-10 2002-01-29 Cytovia, Inc. Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
AU2546399A (en) 1998-02-10 1999-08-30 Yoshitomi Pharmaceutical Industries, Ltd. Preparations with controlled release
CA2698347A1 (en) * 1999-05-20 2000-11-30 Elan Pharma International Limited Multiparticulate controlled release selective serotonin reuptake inhibitor formulations
EP1064938A1 (en) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmaceutical dosage forms for controlled release producing at least a timed pulse
US6475493B1 (en) * 1999-09-02 2002-11-05 Norstrum Pharmaceuticals, Inc. Controlled release pellet formulation
AR026148A1 (es) * 2000-01-21 2003-01-29 Osmotica Argentina S A Dispositivo osmotico con pasaje preformado que aumenta de tamano
WO2002066004A1 (fr) * 2001-02-23 2002-08-29 Mitsubishi Pharma Corporation Compositions a liberation controlee de medicament
CN101982199A (zh) * 2001-11-21 2011-03-02 卫材R&D管理有限公司 含有对酸不稳定的生理活性化合物的制剂组合物及其制法
US20090208579A1 (en) * 2004-12-27 2009-08-20 Eisai R & D Management Co., Ltd. Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
CA2592605C (en) 2004-12-27 2010-12-07 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
CN100398122C (zh) * 2005-01-28 2008-07-02 北京北大药业有限公司 一种治疗颈、腰椎病中药的肠溶包衣组合物
KR20100103565A (ko) * 2008-01-10 2010-09-27 에보니크 룀 게엠베하 촉진되고 조절된 활성 물질 방출을 갖는 코팅된 제약학적 또는 건강기능성 제제
MX2010007579A (es) 2008-01-10 2010-08-03 Evonik Roehm Gmbh Preparacion nutriceutica o farmaceutica revestida con una liberacion de sustancia activa de impulsion mejorada.
JP5674684B2 (ja) * 2009-02-03 2015-02-25 マイクロビオン コーポレーション 上皮組織、急性および慢性創傷、細菌性バイオフィルムならびに他の適応症のための消毒剤としてのビスマス−チオール
US9408393B2 (en) 2010-02-03 2016-08-09 Microbion Corporation Bismuth-thiols as antiseptics for agricultural, industrial and other uses
US9028878B2 (en) 2009-02-03 2015-05-12 Microbion Corporation Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
WO2020028558A1 (en) 2018-07-31 2020-02-06 Microbion Corporation Bismuth-thiol compositions and methods of use
WO2020028561A1 (en) 2018-07-31 2020-02-06 Microbion Corporation Bismuth-thiol compositions and methods for treating wounds
WO2022029938A1 (ja) * 2020-08-05 2022-02-10 マルホ株式会社 皮膚用組成物

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US3236914A (en) * 1959-05-12 1966-02-22 Canadian Ind Method for rendering polymers compatible
US3300429A (en) * 1963-06-17 1967-01-24 Rohm & Haas Aqueous polymeric blends containing ureido monomer
US3369009A (en) * 1964-12-10 1968-02-13 Hercules Inc Azidoformate-containing copolymers
US3641237A (en) * 1970-09-30 1972-02-08 Nat Patent Dev Corp Zero order release constant elution rate drug dosage
US4065523A (en) * 1975-11-24 1977-12-27 Rohm And Haas Company Process for increasing molecular weight of a polymer
US4082705A (en) * 1976-02-05 1978-04-04 Johnson & Johnson Pressure sensitive adhesive compositions
GB2046275A (en) * 1979-03-27 1980-11-12 American Cyanamid Co Granulation and drying aids for polymeric gels
SE8003805L (sv) * 1980-05-21 1981-11-22 Haessle Ab En farmaceutisk beredning med forbettrade utlosningsegenskap
US4539199A (en) * 1981-01-14 1985-09-03 Egyt Gyogyszervegyeszeti Gyar Sustained release pharmaceutical compositions
US4758437A (en) * 1981-12-23 1988-07-19 Yamanouchi Pharmaceutical Co., Ltd. Composition for long acting nicardipine preparation and process of producing the composition
JPS6051106A (ja) * 1983-08-31 1985-03-22 Yamanouchi Pharmaceut Co Ltd 塩酸アモスラロ−ル持続性製剤
JPS60240747A (ja) * 1984-05-15 1985-11-29 Showa Denko Kk 架橋性組成物及びエステル架橋型重合体
JPS62126122A (ja) * 1985-11-27 1987-06-08 Showa Shinyaku Kk 表面コ−テイングされたイブプロフエン顆粒の製法
IL77186A0 (en) * 1985-11-29 1986-04-29 Touitou Elka Pharmaceutical insulin composition
JP2667162B2 (ja) * 1986-11-04 1997-10-27 日本製紙株式会社 インクジエツト記録用シート
SE460946B (sv) * 1987-03-16 1989-12-11 Lejus Medical Ab En multipel-unit-dos komposition av kinidinglukonat

Also Published As

Publication number Publication date
AU5122790A (en) 1990-09-13
GR3017645T3 (en) 1996-01-31
AU623233B2 (en) 1992-05-07
ES2077023T3 (es) 1995-11-16
FI901195A0 (fi) 1990-03-09
ATE124864T1 (de) 1995-07-15
DD292374A5 (de) 1991-08-01
HUT53813A (en) 1990-12-28
NO301578B1 (no) 1997-11-17
KR0140985B1 (ko) 1998-06-01
NO901116D0 (no) 1990-03-09
NO901116L (no) 1990-09-11
EP0386967B1 (en) 1995-07-12
NZ232836A (en) 1991-06-25
EP0386967A3 (en) 1991-04-03
PT93384A (pt) 1990-11-07
KR900013943A (ko) 1990-10-22
DK0386967T3 (da) 1995-11-20
EP0386967A2 (en) 1990-09-12
HU204201B (en) 1991-12-30
CN1045524A (zh) 1990-09-26
CA2011919A1 (en) 1990-09-10
JPH037238A (ja) 1991-01-14
FI97690C (fi) 1997-02-10
DE69020758D1 (de) 1995-08-17
FI97690B (fi) 1996-10-31
PT93384B (pt) 1996-03-29
IE68520B1 (en) 1996-06-26
IE900862L (en) 1990-09-10
HU901380D0 (en) 1990-05-28
US5028664A (en) 1991-07-02
DE69020758T2 (de) 1995-12-07

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