PT93384A - Processo para a preparacao de um material de revestimento de controlo da libertacao de droga para formulacoes de accao prolongada contendo copolimeros de (met)acrilato - Google Patents
Processo para a preparacao de um material de revestimento de controlo da libertacao de droga para formulacoes de accao prolongada contendo copolimeros de (met)acrilatoInfo
- Publication number
- PT93384A PT93384A PT93384A PT9338490A PT93384A PT 93384 A PT93384 A PT 93384A PT 93384 A PT93384 A PT 93384A PT 9338490 A PT9338490 A PT 9338490A PT 93384 A PT93384 A PT 93384A
- Authority
- PT
- Portugal
- Prior art keywords
- coating material
- drug
- acrylate
- release
- meth
- Prior art date
Links
- 239000000463 material Substances 0.000 title abstract 5
- 239000011248 coating agent Substances 0.000 title abstract 4
- 238000000576 coating method Methods 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 4
- 229940079593 drug Drugs 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 title 1
- 229920001577 copolymer Polymers 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000002035 prolonged effect Effects 0.000 title 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000013583 drug formulation Substances 0.000 abstract 1
- 239000012731 long-acting form Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000002861 polymer material Substances 0.000 abstract 1
- IOVGROKTTNBUGK-SJCJKPOMSA-N ritodrine Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC=C(O)C=C1 IOVGROKTTNBUGK-SJCJKPOMSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Paints Or Removers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5868489 | 1989-03-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT93384A true PT93384A (pt) | 1990-11-07 |
| PT93384B PT93384B (pt) | 1996-03-29 |
Family
ID=13091382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT93384A PT93384B (pt) | 1989-03-10 | 1990-03-09 | Processo para a preparacao de um material de revestimento de controlo da libertacao de droga para formulacoes de accao prolongada contendo copolimeros de (met)acrilato |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5028664A (pt) |
| EP (1) | EP0386967B1 (pt) |
| JP (1) | JPH037238A (pt) |
| KR (1) | KR0140985B1 (pt) |
| CN (1) | CN1045524A (pt) |
| AT (1) | ATE124864T1 (pt) |
| AU (1) | AU623233B2 (pt) |
| CA (1) | CA2011919A1 (pt) |
| DD (2) | DD298205A5 (pt) |
| DE (1) | DE69020758T2 (pt) |
| DK (1) | DK0386967T3 (pt) |
| ES (1) | ES2077023T3 (pt) |
| FI (1) | FI97690C (pt) |
| GR (1) | GR3017645T3 (pt) |
| HU (1) | HU204201B (pt) |
| IE (1) | IE68520B1 (pt) |
| NO (1) | NO301578B1 (pt) |
| NZ (1) | NZ232836A (pt) |
| PT (1) | PT93384B (pt) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GEP19971086B (en) * | 1991-02-22 | 1997-12-02 | Tillotts Pharma Ag | Peroral Pharmaceutically Dispensed Form for Selective Introducing of the Medicine into the Intestine |
| GB9200607D0 (en) * | 1992-01-13 | 1992-03-11 | Ethical Pharma Ltd | Pharmaceutical compositions containing nifedipine and process for the preparation thereof |
| US20030170290A1 (en) * | 1993-06-16 | 2003-09-11 | Shug Austin L. | Delayed release carnitine |
| WO1995005168A1 (en) * | 1993-08-19 | 1995-02-23 | Shug Austin L | Delayed release carnitine |
| DE9414066U1 (de) * | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform |
| NZ270078A (en) * | 1994-12-06 | 1998-05-27 | Bernard Charles Sherman | Diltiazem hydrochloride formulation comprising beads with immediate, intermediate, and delayed release dissolution profiles |
| US5567441A (en) * | 1995-03-24 | 1996-10-22 | Andrx Pharmaceuticals Inc. | Diltiazem controlled release formulation |
| ES2199289T3 (es) * | 1995-07-26 | 2004-02-16 | Kyowa Hakko Kogyo Co., Ltd. | Dispersion solida de derivados de xantina. |
| US6162463A (en) * | 1997-05-01 | 2000-12-19 | Dov Pharmaceutical Inc | Extended release formulation of diltiazem hydrochloride |
| US6342611B1 (en) * | 1997-10-10 | 2002-01-29 | Cytovia, Inc. | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof |
| CA2320193A1 (en) | 1998-02-10 | 1999-08-19 | Welfide Corporation | Controlled release preparation |
| ES2290027T3 (es) * | 1999-05-20 | 2008-02-16 | Elan Corporation, Plc | Formulaciones multiparticuladas y de liberacion controlada de inhibidores selectivos de la recaptacion de serotonina. |
| EP1064938A1 (en) * | 1999-06-28 | 2001-01-03 | Sanofi-Synthelabo | Pharmaceutical dosage forms for controlled release producing at least a timed pulse |
| WO2001015668A1 (en) * | 1999-09-02 | 2001-03-08 | Nostrum Pharmaceuticals, Inc. | Controlled release pellet formulation |
| AR026148A1 (es) * | 2000-01-21 | 2003-01-29 | Osmotica Argentina S A | Dispositivo osmotico con pasaje preformado que aumenta de tamano |
| WO2002066004A1 (fr) * | 2001-02-23 | 2002-08-29 | Mitsubishi Pharma Corporation | Compositions a liberation controlee de medicament |
| MXPA04004775A (es) * | 2001-11-21 | 2005-02-17 | Eisai Co Ltd | Composicion de preparacion que contiene un compuesto fisiologicamente activo inestable de acido y un proceso para producirlo. |
| SE0201110D0 (sv) * | 2002-04-12 | 2002-04-12 | Astrazeneca Ab | New film coating |
| AU2005320547B2 (en) | 2004-12-27 | 2009-02-05 | Eisai R & D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
| US20090208579A1 (en) * | 2004-12-27 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same |
| US20060246003A1 (en) * | 2004-12-27 | 2006-11-02 | Eisai Co. Ltd. | Composition containing anti-dementia drug |
| CN100398122C (zh) * | 2005-01-28 | 2008-07-02 | 北京北大药业有限公司 | 一种治疗颈、腰椎病中药的肠溶包衣组合物 |
| CA2711475A1 (en) * | 2008-01-10 | 2009-07-16 | Evonik Roehm Gmbh | Coated pharmaceutical or nutraceutical preparation with accelerated controlled active substance release |
| US9011907B2 (en) * | 2008-01-10 | 2015-04-21 | Evonik Röhm Gmbh | Coated pharmaceutical or nutraceutical preparation with enhanced pulsed active substance release |
| US8389021B2 (en) * | 2009-02-03 | 2013-03-05 | Microbion Corporation | Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications |
| US9408393B2 (en) | 2010-02-03 | 2016-08-09 | Microbion Corporation | Bismuth-thiols as antiseptics for agricultural, industrial and other uses |
| US9028878B2 (en) | 2009-02-03 | 2015-05-12 | Microbion Corporation | Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses |
| MX2021001276A (es) | 2018-07-31 | 2021-07-15 | Microbion Corp | Composiciones de bismuto-tiol y metodos para tratar heridas. |
| MX2021001272A (es) | 2018-07-31 | 2021-07-15 | Microbion Corp | Composiciones de bismuto-tiol y metodos de uso. |
| WO2022029938A1 (ja) * | 2020-08-05 | 2022-02-10 | マルホ株式会社 | 皮膚用組成物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3236914A (en) * | 1959-05-12 | 1966-02-22 | Canadian Ind | Method for rendering polymers compatible |
| US3300429A (en) * | 1963-06-17 | 1967-01-24 | Rohm & Haas | Aqueous polymeric blends containing ureido monomer |
| US3369009A (en) * | 1964-12-10 | 1968-02-13 | Hercules Inc | Azidoformate-containing copolymers |
| US3641237A (en) * | 1970-09-30 | 1972-02-08 | Nat Patent Dev Corp | Zero order release constant elution rate drug dosage |
| US4065523A (en) * | 1975-11-24 | 1977-12-27 | Rohm And Haas Company | Process for increasing molecular weight of a polymer |
| US4082705A (en) * | 1976-02-05 | 1978-04-04 | Johnson & Johnson | Pressure sensitive adhesive compositions |
| GB2046275A (en) * | 1979-03-27 | 1980-11-12 | American Cyanamid Co | Granulation and drying aids for polymeric gels |
| SE8003805L (sv) * | 1980-05-21 | 1981-11-22 | Haessle Ab | En farmaceutisk beredning med forbettrade utlosningsegenskap |
| US4539199A (en) * | 1981-01-14 | 1985-09-03 | Egyt Gyogyszervegyeszeti Gyar | Sustained release pharmaceutical compositions |
| US4758437A (en) * | 1981-12-23 | 1988-07-19 | Yamanouchi Pharmaceutical Co., Ltd. | Composition for long acting nicardipine preparation and process of producing the composition |
| JPS6051106A (ja) * | 1983-08-31 | 1985-03-22 | Yamanouchi Pharmaceut Co Ltd | 塩酸アモスラロ−ル持続性製剤 |
| JPS60240747A (ja) * | 1984-05-15 | 1985-11-29 | Showa Denko Kk | 架橋性組成物及びエステル架橋型重合体 |
| JPS62126122A (ja) * | 1985-11-27 | 1987-06-08 | Showa Shinyaku Kk | 表面コ−テイングされたイブプロフエン顆粒の製法 |
| IL77186A0 (en) * | 1985-11-29 | 1986-04-29 | Touitou Elka | Pharmaceutical insulin composition |
| JP2667162B2 (ja) * | 1986-11-04 | 1997-10-27 | 日本製紙株式会社 | インクジエツト記録用シート |
| SE460946B (sv) * | 1987-03-16 | 1989-12-11 | Lejus Medical Ab | En multipel-unit-dos komposition av kinidinglukonat |
-
1990
- 1990-03-05 ES ES90302287T patent/ES2077023T3/es not_active Expired - Lifetime
- 1990-03-05 AT AT90302287T patent/ATE124864T1/de not_active IP Right Cessation
- 1990-03-05 EP EP90302287A patent/EP0386967B1/en not_active Expired - Lifetime
- 1990-03-05 DE DE69020758T patent/DE69020758T2/de not_active Expired - Fee Related
- 1990-03-05 DK DK90302287.9T patent/DK0386967T3/da active
- 1990-03-07 NZ NZ232836A patent/NZ232836A/en unknown
- 1990-03-08 US US07/490,831 patent/US5028664A/en not_active Expired - Fee Related
- 1990-03-09 IE IE86290A patent/IE68520B1/en not_active IP Right Cessation
- 1990-03-09 HU HU901380A patent/HU204201B/hu unknown
- 1990-03-09 CA CA002011919A patent/CA2011919A1/en not_active Abandoned
- 1990-03-09 PT PT93384A patent/PT93384B/pt not_active IP Right Cessation
- 1990-03-09 AU AU51227/90A patent/AU623233B2/en not_active Ceased
- 1990-03-09 FI FI901195A patent/FI97690C/fi not_active IP Right Cessation
- 1990-03-09 JP JP2059746A patent/JPH037238A/ja active Pending
- 1990-03-09 NO NO901116A patent/NO301578B1/no unknown
- 1990-03-09 KR KR1019900003097A patent/KR0140985B1/ko not_active Expired - Fee Related
- 1990-03-10 CN CN90101329A patent/CN1045524A/zh active Pending
- 1990-03-12 DD DD90344294A patent/DD298205A5/de not_active IP Right Cessation
- 1990-03-12 DD DD90338614A patent/DD292374A5/de not_active IP Right Cessation
-
1995
- 1995-10-04 GR GR950402758T patent/GR3017645T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU901380D0 (en) | 1990-05-28 |
| HUT53813A (en) | 1990-12-28 |
| NO301578B1 (no) | 1997-11-17 |
| EP0386967A3 (en) | 1991-04-03 |
| DK0386967T3 (da) | 1995-11-20 |
| ES2077023T3 (es) | 1995-11-16 |
| NO901116L (no) | 1990-09-11 |
| JPH037238A (ja) | 1991-01-14 |
| EP0386967A2 (en) | 1990-09-12 |
| AU5122790A (en) | 1990-09-13 |
| DD292374A5 (de) | 1991-08-01 |
| DD298205A5 (de) | 1992-02-13 |
| ATE124864T1 (de) | 1995-07-15 |
| FI901195A0 (fi) | 1990-03-09 |
| FI97690B (fi) | 1996-10-31 |
| EP0386967B1 (en) | 1995-07-12 |
| IE900862L (en) | 1990-09-10 |
| DE69020758T2 (de) | 1995-12-07 |
| DE69020758D1 (de) | 1995-08-17 |
| KR0140985B1 (ko) | 1998-06-01 |
| FI97690C (fi) | 1997-02-10 |
| IE68520B1 (en) | 1996-06-26 |
| KR900013943A (ko) | 1990-10-22 |
| US5028664A (en) | 1991-07-02 |
| AU623233B2 (en) | 1992-05-07 |
| PT93384B (pt) | 1996-03-29 |
| CN1045524A (zh) | 1990-09-26 |
| CA2011919A1 (en) | 1990-09-10 |
| HU204201B (en) | 1991-12-30 |
| GR3017645T3 (en) | 1996-01-31 |
| NO901116D0 (no) | 1990-03-09 |
| NZ232836A (en) | 1991-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19951204 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20000630 |