DD296843A5 - Monoklonale antikoerper zur indukzierung von tobranz - Google Patents
Monoklonale antikoerper zur indukzierung von tobranz Download PDFInfo
- Publication number
- DD296843A5 DD296843A5 DD90341218A DD34121890A DD296843A5 DD 296843 A5 DD296843 A5 DD 296843A5 DD 90341218 A DD90341218 A DD 90341218A DD 34121890 A DD34121890 A DD 34121890A DD 296843 A5 DD296843 A5 DD 296843A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- exhaustive
- antibody
- monoclonal
- tolerance
- antigen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2815—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898912497A GB8912497D0 (en) | 1989-05-31 | 1989-05-31 | Monoclonal antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD296843A5 true DD296843A5 (de) | 1991-12-19 |
Family
ID=10657649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD90341218A DD296843A5 (de) | 1989-05-31 | 1990-05-31 | Monoklonale antikoerper zur indukzierung von tobranz |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0474691B1 (pt) |
| JP (1) | JP2763197B2 (pt) |
| KR (1) | KR0183029B1 (pt) |
| AT (1) | ATE145246T1 (pt) |
| AU (1) | AU657255B2 (pt) |
| CA (1) | CA2055615C (pt) |
| DD (1) | DD296843A5 (pt) |
| DE (1) | DE69029134T2 (pt) |
| DK (1) | DK0474691T3 (pt) |
| ES (1) | ES2096588T3 (pt) |
| GB (1) | GB8912497D0 (pt) |
| HU (1) | HUT61341A (pt) |
| IE (1) | IE80735B1 (pt) |
| IL (1) | IL94566A0 (pt) |
| MY (1) | MY135673A (pt) |
| NZ (1) | NZ233889A (pt) |
| PT (1) | PT94214B (pt) |
| WO (1) | WO1990015152A1 (pt) |
| ZA (1) | ZA904174B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9100741D0 (en) * | 1991-01-14 | 1991-02-27 | Univ London | Treatment of disease |
| US6136310A (en) * | 1991-07-25 | 2000-10-24 | Idec Pharmaceuticals Corporation | Recombinant anti-CD4 antibodies for human therapy |
| JPH08500826A (ja) * | 1992-08-21 | 1996-01-30 | ジェネンテク，インコーポレイテッド | Ｌｆａ−１仲介疾患を処置する方法 |
| US6270766B1 (en) | 1992-10-08 | 2001-08-07 | The Kennedy Institute Of Rheumatology | Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease |
| CA2221350A1 (en) * | 1995-05-18 | 1996-11-21 | Ortho Pharmaceutical Corporation | Induction of immunological tolerance by the use of non-depleting anti-cd4 antibodies |
| EP3214175A1 (en) | 1999-08-24 | 2017-09-06 | E. R. Squibb & Sons, L.L.C. | Human ctla-4 antibodies and their uses |
| US7011952B2 (en) | 2000-02-22 | 2006-03-14 | University Of Iowa Research Foundation | Diagnostics and therapeutics for macular degeneration-related disorders |
| ATE412185T1 (de) | 2000-04-29 | 2008-11-15 | Univ Iowa Res Found | Diagnostika und therapeutika für makula degeneration erkrankungen |
| US7541443B2 (en) * | 2001-06-14 | 2009-06-02 | Tolerrx, Inc. | Anti-CD4 antibodies |
| DE60238533D1 (de) * | 2001-06-14 | 2011-01-20 | Cambridge Entpr Ltd | Nicht-depletierender Antikörper TRX-1 gegen CD4 und dessen Verwendungen |
| EP1460088A1 (en) | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
| GB0314461D0 (en) * | 2003-06-20 | 2003-07-23 | Isis Innovation | Suppression of transplant rejection |
| EP1758936A2 (en) * | 2004-06-22 | 2007-03-07 | Tolerrx Inc. | Optimized dosing with anti-cd4 antibodies for tolerance induction in primates |
| KR20100135257A (ko) | 2008-03-13 | 2010-12-24 | 바이오테스트 아게 | 질병 치료제 |
| CA2718191C (en) | 2008-03-13 | 2018-05-15 | Biotest Ag | Agent for treating disease |
| BRPI0909179A2 (pt) | 2008-03-13 | 2015-08-25 | Biotest Ag | Composição farmacêutica, e, método de tratamento de uma doença autoimune. |
| MX2010013265A (es) * | 2008-06-06 | 2011-02-24 | Baylor Res Inst | Anticuerpos anti-cd8 bloquean cebado de efectores citotoxicos y conducen a generacion de celulas t cd8+ reguladoras. |
| WO2010009129A2 (en) * | 2008-07-15 | 2010-01-21 | Genentech, Inc. | Methods of treating autoimmune diseases using cd4 antibodies |
| GB0920944D0 (en) | 2009-11-30 | 2010-01-13 | Biotest Ag | Agents for treating disease |
| WO2024112867A1 (en) | 2022-11-23 | 2024-05-30 | University Of Georgia Research Foundation, Inc. | Compositions and methods of use thereof for increasing immune responses |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8608068D0 (en) * | 1986-04-02 | 1986-05-08 | Cobbold S P | Monoclonal antibodies |
-
1989
- 1989-05-31 GB GB898912497A patent/GB8912497D0/en active Pending
-
1990
- 1990-05-30 ZA ZA904174A patent/ZA904174B/xx unknown
- 1990-05-31 AU AU57258/90A patent/AU657255B2/en not_active Expired
- 1990-05-31 IE IE194990A patent/IE80735B1/en not_active IP Right Cessation
- 1990-05-31 HU HU905134A patent/HUT61341A/hu unknown
- 1990-05-31 NZ NZ233889A patent/NZ233889A/en unknown
- 1990-05-31 AT AT90908270T patent/ATE145246T1/de not_active IP Right Cessation
- 1990-05-31 DK DK90908270.3T patent/DK0474691T3/da active
- 1990-05-31 KR KR1019910701737A patent/KR0183029B1/ko not_active IP Right Cessation
- 1990-05-31 ES ES90908270T patent/ES2096588T3/es not_active Expired - Lifetime
- 1990-05-31 CA CA002055615A patent/CA2055615C/en not_active Expired - Lifetime
- 1990-05-31 DE DE69029134T patent/DE69029134T2/de not_active Expired - Lifetime
- 1990-05-31 EP EP90908270A patent/EP0474691B1/en not_active Expired - Lifetime
- 1990-05-31 DD DD90341218A patent/DD296843A5/de not_active IP Right Cessation
- 1990-05-31 IL IL94566A patent/IL94566A0/xx unknown
- 1990-05-31 MY MYPI90000913A patent/MY135673A/en unknown
- 1990-05-31 WO PCT/GB1990/000840 patent/WO1990015152A1/en active IP Right Grant
- 1990-05-31 PT PT94214A patent/PT94214B/pt not_active IP Right Cessation
- 1990-05-31 JP JP2508030A patent/JP2763197B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU5725890A (en) | 1991-01-07 |
| ES2096588T3 (es) | 1997-03-16 |
| DE69029134D1 (de) | 1996-12-19 |
| WO1990015152A1 (en) | 1990-12-13 |
| JPH04505919A (ja) | 1992-10-15 |
| CA2055615A1 (en) | 1990-12-13 |
| PT94214B (pt) | 1997-03-31 |
| GB8912497D0 (en) | 1989-07-19 |
| IE80735B1 (en) | 1998-12-30 |
| EP0474691A1 (en) | 1992-03-18 |
| ZA904174B (en) | 1992-02-26 |
| PT94214A (pt) | 1991-02-08 |
| ATE145246T1 (de) | 1996-11-15 |
| KR0183029B1 (ko) | 1999-04-01 |
| NZ233889A (en) | 1997-06-24 |
| CA2055615C (en) | 2001-07-17 |
| MY135673A (en) | 2008-06-30 |
| JP2763197B2 (ja) | 1998-06-11 |
| DK0474691T3 (da) | 1996-12-02 |
| AU657255B2 (en) | 1995-03-09 |
| IL94566A0 (en) | 1991-03-10 |
| IE901949L (en) | 1990-11-30 |
| HUT61341A (en) | 1992-12-28 |
| EP0474691B1 (en) | 1996-11-13 |
| HU905134D0 (en) | 1992-02-28 |
| DE69029134T2 (de) | 1997-03-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DD296843A5 (de) | Monoklonale antikoerper zur indukzierung von tobranz | |
| DE69723888T2 (de) | Gemischter Chimerismus und Toleranz | |
| US6056956A (en) | Non-depleting anti-CD4 monoclonal antibodies and tolerance induction | |
| DE69032484T4 (de) | Zusammensetzungen und deren verwendung zur förderung der immunopotentiation | |
| DE69733960T2 (de) | Verwendung von Antikörpern gegen CD45RO Leukozytenantigen zur Immunmodulation | |
| DE69713499T3 (de) | Verfahren zur inhibierung der immunreaktion durch blockierung der gp39/cd40 und ctla4/cd28/b7 routen und zusammensetzung zu deren verwendung | |
| DE69315847T2 (de) | Verfahren zur behandlung einer durch lfa-1 vermittelten störung | |
| DE69533984T2 (de) | Verfahren zur anregung von t-zelltoleranz gegen ein gewebe- oder organtransplantat | |
| Qin et al. | CD4 monoclonal antibody pairs for immunosuppression and tolerance induction | |
| EP1115427B1 (de) | Verwendung von tumorzellen zeitversetzt in kombination mit intakten antikörpern zur immunisierung | |
| DE69916807T2 (de) | Kostimulatorische blockade und gemischter chimerismus in allotransplantationen | |
| DE69031919T2 (de) | T-zell-rezeptor-peptide als heilmittel für autoimmune und bösartige krankheiten | |
| DE69333591T2 (de) | CD40CR-Rezeptor und Liganden dafür | |
| DE69504955T2 (de) | Immunstimulierende monoklonale antikörper | |
| DE69131331T2 (de) | Dauerhafte Verpflanzung und Entwicklung menschlicher hämatopoietischer Zellinien bei normalen Säugetieren | |
| DE69431107T2 (de) | Die erzeugung von toleranz gegen fremdtransplantate durch tolerogenese mit hilfe von ersatzlebewesen | |
| DE10212108A1 (de) | Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer pharmazeutischen Zusammensetzung | |
| EP1600164A2 (de) | Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer Pharmazeutischen Zusammensetzung mit dosisabhängiger Wirkung | |
| EP1331944B1 (de) | Verwendung cd28 spezifischer monoklonaler antikörper zur stimulation von blutzellen, welche kein cd28 tragen | |
| DE69535713T2 (de) | Verfahren zur modulierung von t-zellreaktionen durch manipulation einer gemeinsamen zytokinrezeptor-gammakette | |
| DE69737888T2 (de) | Anti-mhc klasse ii bindungsreagentien zur verwendung bei xenotransplantationen | |
| OCHIAI et al. | Specificity and immunosuppressive potency of a rabbit antimouse T cell-specific antiserum | |
| DE69928407T2 (de) | Ex vivo behandlung von allogenen und xenogenen t-zellen mit gp39-antagonisten | |
| DE4312916C2 (de) | Arzneimittel zur Behandlung von Immunreaktionen | |
| DE69431184T2 (de) | Ein thymus-fremdtransplantat |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ENJ | Ceased due to non-payment of renewal fee |