DD283624A5 - Verfahren zur herstellung von neuartigem 5-(substituiertes-amino)-8-(phenyl oder substituiertes-phenyl)-3h,6h-1,4,5a,8a-tetraazaacenaphthylen-3-one - Google Patents

Verfahren zur herstellung von neuartigem 5-(substituiertes-amino)-8-(phenyl oder substituiertes-phenyl)-3h,6h-1,4,5a,8a-tetraazaacenaphthylen-3-one Download PDF

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Publication number
DD283624A5
DD283624A5 DD89325854A DD32585489A DD283624A5 DD 283624 A5 DD283624 A5 DD 283624A5 DD 89325854 A DD89325854 A DD 89325854A DD 32585489 A DD32585489 A DD 32585489A DD 283624 A5 DD283624 A5 DD 283624A5
Authority
DD
German Democratic Republic
Prior art keywords
phenyl
trifluoromethyl
stirred
mixture
tetraazaacenaphthylene
Prior art date
Application number
DD89325854A
Other languages
German (de)
English (en)
Inventor
Joseph W Epstein
Jeremy I Levin
Shin S Tseng
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by ��@���������@�������k�� filed Critical ��@���������@�������k��
Publication of DD283624A5 publication Critical patent/DD283624A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DD89325854A 1988-02-22 1989-02-20 Verfahren zur herstellung von neuartigem 5-(substituiertes-amino)-8-(phenyl oder substituiertes-phenyl)-3h,6h-1,4,5a,8a-tetraazaacenaphthylen-3-one DD283624A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15844888A 1988-02-22 1988-02-22

Publications (1)

Publication Number Publication Date
DD283624A5 true DD283624A5 (de) 1990-10-17

Family

ID=22568168

Family Applications (1)

Application Number Title Priority Date Filing Date
DD89325854A DD283624A5 (de) 1988-02-22 1989-02-20 Verfahren zur herstellung von neuartigem 5-(substituiertes-amino)-8-(phenyl oder substituiertes-phenyl)-3h,6h-1,4,5a,8a-tetraazaacenaphthylen-3-one

Country Status (23)

Country Link
EP (1) EP0329940B1 (pt)
JP (1) JP2641556B2 (pt)
KR (1) KR970009226B1 (pt)
AR (1) AR247211A1 (pt)
AT (1) ATE99686T1 (pt)
AU (1) AU611769B2 (pt)
CA (1) CA1329594C (pt)
CZ (1) CZ284273B6 (pt)
DD (1) DD283624A5 (pt)
DE (1) DE68911951T2 (pt)
DK (1) DK172397B1 (pt)
ES (1) ES2061739T3 (pt)
FI (1) FI89922C (pt)
HU (1) HU203554B (pt)
IE (1) IE64147B1 (pt)
IL (1) IL88974A (pt)
NO (1) NO169589C (pt)
NZ (1) NZ228009A (pt)
PH (1) PH26358A (pt)
PL (1) PL158865B1 (pt)
PT (1) PT89766B (pt)
SK (1) SK105589A3 (pt)
ZA (1) ZA891310B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013737A (en) * 1988-02-22 1991-05-07 American Cyanamid Company 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones
EP0562236A1 (en) * 1992-03-26 1993-09-29 American Cyanamid Company Process for the synthesis of 5-[(substituted)-amino]-8-[phenyl or substiutued-phenyl]-3H, 6H-1, 4, 5A, 8A-tetraazaacephthylen-3-ones
EP0957918A1 (en) * 1996-12-19 1999-11-24 American Cyanamid Company Method of treating or inhibiting neutropenia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
US4576943A (en) * 1984-10-09 1986-03-18 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines
EP0264773A1 (en) * 1986-10-16 1988-04-27 American Cyanamid Company 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines

Also Published As

Publication number Publication date
ZA891310B (en) 1989-11-29
PT89766B (pt) 1994-03-31
EP0329940B1 (en) 1994-01-05
HU203554B (en) 1991-08-28
DK79589D0 (da) 1989-02-21
JP2641556B2 (ja) 1997-08-13
IL88974A (en) 1993-03-15
CA1329594C (en) 1994-05-17
JPH01249774A (ja) 1989-10-05
KR970009226B1 (en) 1997-06-09
CZ105589A3 (cs) 1998-07-15
FI890826A (fi) 1989-08-23
NO169589B (no) 1992-04-06
PL158865B1 (pl) 1992-10-30
DE68911951T2 (de) 1994-06-01
KR890013022A (ko) 1989-09-20
DK172397B1 (da) 1998-05-18
AR247211A1 (es) 1994-11-30
PT89766A (pt) 1989-10-04
EP0329940A1 (en) 1989-08-30
FI890826A0 (fi) 1989-02-21
IE64147B1 (en) 1995-07-12
NZ228009A (en) 1991-09-25
FI89922B (fi) 1993-08-31
IE890543L (en) 1989-08-22
IL88974A0 (en) 1989-08-15
ES2061739T3 (es) 1994-12-16
DE68911951D1 (de) 1994-02-17
SK279319B6 (sk) 1998-09-09
AU611769B2 (en) 1991-06-20
DK79589A (da) 1989-08-23
PH26358A (en) 1992-04-29
AU3017289A (en) 1989-08-24
PL277837A1 (en) 1989-11-13
FI89922C (fi) 1993-12-10
SK105589A3 (en) 1998-09-09
CZ284273B6 (cs) 1998-10-14
NO890724D0 (no) 1989-02-21
HUT51626A (en) 1990-05-28
NO890724L (no) 1989-08-23
ATE99686T1 (de) 1994-01-15
NO169589C (no) 1992-07-15

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