ZA891310B - 5-(substituted-amino)-8-(phenyl or substituted-phenyl)-3h,6h-1,4,5a,8a-tetraazaacenaphthyen-3-ones - Google Patents

5-(substituted-amino)-8-(phenyl or substituted-phenyl)-3h,6h-1,4,5a,8a-tetraazaacenaphthyen-3-ones

Info

Publication number
ZA891310B
ZA891310B ZA891310A ZA891310A ZA891310B ZA 891310 B ZA891310 B ZA 891310B ZA 891310 A ZA891310 A ZA 891310A ZA 891310 A ZA891310 A ZA 891310A ZA 891310 B ZA891310 B ZA 891310B
Authority
ZA
South Africa
Prior art keywords
phenyl
substituted
tetraazaacenaphthyen
ones
amino
Prior art date
Application number
ZA891310A
Other languages
English (en)
Inventor
Joseph William Epstein
William Epstein Joseph
Jeremy Ian Levin
Ian Levin Jeremy
Shin Shyong Tseng
Shyong Tseng Shin
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ZA891310B publication Critical patent/ZA891310B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA891310A 1988-02-22 1989-02-21 5-(substituted-amino)-8-(phenyl or substituted-phenyl)-3h,6h-1,4,5a,8a-tetraazaacenaphthyen-3-ones ZA891310B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15844888A 1988-02-22 1988-02-22

Publications (1)

Publication Number Publication Date
ZA891310B true ZA891310B (en) 1989-11-29

Family

ID=22568168

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA891310A ZA891310B (en) 1988-02-22 1989-02-21 5-(substituted-amino)-8-(phenyl or substituted-phenyl)-3h,6h-1,4,5a,8a-tetraazaacenaphthyen-3-ones

Country Status (23)

Country Link
EP (1) EP0329940B1 (xx)
JP (1) JP2641556B2 (xx)
KR (1) KR970009226B1 (xx)
AR (1) AR247211A1 (xx)
AT (1) ATE99686T1 (xx)
AU (1) AU611769B2 (xx)
CA (1) CA1329594C (xx)
CZ (1) CZ284273B6 (xx)
DD (1) DD283624A5 (xx)
DE (1) DE68911951T2 (xx)
DK (1) DK172397B1 (xx)
ES (1) ES2061739T3 (xx)
FI (1) FI89922C (xx)
HU (1) HU203554B (xx)
IE (1) IE64147B1 (xx)
IL (1) IL88974A (xx)
NO (1) NO169589C (xx)
NZ (1) NZ228009A (xx)
PH (1) PH26358A (xx)
PL (1) PL158865B1 (xx)
PT (1) PT89766B (xx)
SK (1) SK105589A3 (xx)
ZA (1) ZA891310B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013737A (en) * 1988-02-22 1991-05-07 American Cyanamid Company 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones
EP0562236A1 (en) * 1992-03-26 1993-09-29 American Cyanamid Company Process for the synthesis of 5-[(substituted)-amino]-8-[phenyl or substiutued-phenyl]-3H, 6H-1, 4, 5A, 8A-tetraazaacephthylen-3-ones
EP0957918A1 (en) * 1996-12-19 1999-11-24 American Cyanamid Company Method of treating or inhibiting neutropenia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
US4576943A (en) * 1984-10-09 1986-03-18 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines
EP0264773A1 (en) * 1986-10-16 1988-04-27 American Cyanamid Company 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines

Also Published As

Publication number Publication date
HUT51626A (en) 1990-05-28
AU3017289A (en) 1989-08-24
FI89922C (fi) 1993-12-10
DK79589A (da) 1989-08-23
DD283624A5 (de) 1990-10-17
IL88974A0 (en) 1989-08-15
JPH01249774A (ja) 1989-10-05
CZ284273B6 (cs) 1998-10-14
IE890543L (en) 1989-08-22
EP0329940B1 (en) 1994-01-05
AR247211A1 (es) 1994-11-30
CA1329594C (en) 1994-05-17
ES2061739T3 (es) 1994-12-16
IE64147B1 (en) 1995-07-12
FI89922B (fi) 1993-08-31
FI890826A0 (fi) 1989-02-21
SK279319B6 (sk) 1998-09-09
HU203554B (en) 1991-08-28
NZ228009A (en) 1991-09-25
NO890724D0 (no) 1989-02-21
PT89766B (pt) 1994-03-31
PL277837A1 (en) 1989-11-13
IL88974A (en) 1993-03-15
DE68911951T2 (de) 1994-06-01
SK105589A3 (en) 1998-09-09
CZ105589A3 (cs) 1998-07-15
ATE99686T1 (de) 1994-01-15
NO169589B (no) 1992-04-06
PT89766A (pt) 1989-10-04
DE68911951D1 (de) 1994-02-17
DK79589D0 (da) 1989-02-21
JP2641556B2 (ja) 1997-08-13
EP0329940A1 (en) 1989-08-30
PH26358A (en) 1992-04-29
NO169589C (no) 1992-07-15
FI890826A (fi) 1989-08-23
PL158865B1 (pl) 1992-10-30
AU611769B2 (en) 1991-06-20
NO890724L (no) 1989-08-23
KR970009226B1 (en) 1997-06-09
KR890013022A (ko) 1989-09-20
DK172397B1 (da) 1998-05-18

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