SK105589A3 - 5-(subst.amino)-8-(phenyl or subst.phenyl)-3h,6h-1,4,5a,8a- -tetraazaacenaphtylen-3-ones and manufacturing process thereof - Google Patents

5-(subst.amino)-8-(phenyl or subst.phenyl)-3h,6h-1,4,5a,8a- -tetraazaacenaphtylen-3-ones and manufacturing process thereof Download PDF

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Publication number
SK105589A3
SK105589A3 SK1055-89A SK105589A SK105589A3 SK 105589 A3 SK105589 A3 SK 105589A3 SK 105589 A SK105589 A SK 105589A SK 105589 A3 SK105589 A3 SK 105589A3
Authority
SK
Slovakia
Prior art keywords
phenyl
tetraazaacenaphthylen
trifluoromethyl
mixture
stirred
Prior art date
Application number
SK1055-89A
Other languages
English (en)
Slovak (sk)
Other versions
SK279319B6 (sk
Inventor
Joseph W Epstein
Jeremy I Levin
Shin Shyong Tseng
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of SK105589A3 publication Critical patent/SK105589A3/sk
Publication of SK279319B6 publication Critical patent/SK279319B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SK1055-89A 1988-02-22 1989-02-17 5-(subst.amino)-8-(fenyl alebo subst.fenyl)-3h, 6h SK279319B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15844888A 1988-02-22 1988-02-22

Publications (2)

Publication Number Publication Date
SK105589A3 true SK105589A3 (en) 1998-09-09
SK279319B6 SK279319B6 (sk) 1998-09-09

Family

ID=22568168

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1055-89A SK279319B6 (sk) 1988-02-22 1989-02-17 5-(subst.amino)-8-(fenyl alebo subst.fenyl)-3h, 6h

Country Status (23)

Country Link
EP (1) EP0329940B1 (xx)
JP (1) JP2641556B2 (xx)
KR (1) KR970009226B1 (xx)
AR (1) AR247211A1 (xx)
AT (1) ATE99686T1 (xx)
AU (1) AU611769B2 (xx)
CA (1) CA1329594C (xx)
CZ (1) CZ284273B6 (xx)
DD (1) DD283624A5 (xx)
DE (1) DE68911951T2 (xx)
DK (1) DK172397B1 (xx)
ES (1) ES2061739T3 (xx)
FI (1) FI89922C (xx)
HU (1) HU203554B (xx)
IE (1) IE64147B1 (xx)
IL (1) IL88974A (xx)
NO (1) NO169589C (xx)
NZ (1) NZ228009A (xx)
PH (1) PH26358A (xx)
PL (1) PL158865B1 (xx)
PT (1) PT89766B (xx)
SK (1) SK279319B6 (xx)
ZA (1) ZA891310B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013737A (en) * 1988-02-22 1991-05-07 American Cyanamid Company 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones
SG47588A1 (en) * 1992-03-26 1998-04-17 American Cyanamid Co An improved process for the synthesis of 5-[(substituted) amino] -8- [phenyl or substituted-phenyl]-3H, 6H-1, 4, 5A, 8A-tetraazaacenaphtylen-3- ones
JP2001506998A (ja) * 1996-12-19 2001-05-29 アメリカン・サイアナミド・カンパニー 好中球減少症の治療または抑制方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
US4576943A (en) * 1984-10-09 1986-03-18 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines
EP0264773A1 (en) * 1986-10-16 1988-04-27 American Cyanamid Company 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines

Also Published As

Publication number Publication date
KR970009226B1 (en) 1997-06-09
EP0329940A1 (en) 1989-08-30
FI89922B (fi) 1993-08-31
FI890826A0 (fi) 1989-02-21
FI89922C (fi) 1993-12-10
NO169589B (no) 1992-04-06
DK79589D0 (da) 1989-02-21
PH26358A (en) 1992-04-29
PT89766A (pt) 1989-10-04
NO890724L (no) 1989-08-23
DD283624A5 (de) 1990-10-17
IE890543L (en) 1989-08-22
CZ105589A3 (cs) 1998-07-15
CA1329594C (en) 1994-05-17
FI890826A (fi) 1989-08-23
EP0329940B1 (en) 1994-01-05
DE68911951D1 (de) 1994-02-17
KR890013022A (ko) 1989-09-20
IE64147B1 (en) 1995-07-12
ZA891310B (en) 1989-11-29
PL158865B1 (pl) 1992-10-30
AU611769B2 (en) 1991-06-20
IL88974A (en) 1993-03-15
PL277837A1 (en) 1989-11-13
NO890724D0 (no) 1989-02-21
PT89766B (pt) 1994-03-31
CZ284273B6 (cs) 1998-10-14
DK79589A (da) 1989-08-23
SK279319B6 (sk) 1998-09-09
ES2061739T3 (es) 1994-12-16
AU3017289A (en) 1989-08-24
DE68911951T2 (de) 1994-06-01
ATE99686T1 (de) 1994-01-15
AR247211A1 (es) 1994-11-30
IL88974A0 (en) 1989-08-15
JP2641556B2 (ja) 1997-08-13
NZ228009A (en) 1991-09-25
NO169589C (no) 1992-07-15
HUT51626A (en) 1990-05-28
DK172397B1 (da) 1998-05-18
HU203554B (en) 1991-08-28
JPH01249774A (ja) 1989-10-05

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