ATE99686T1 - 5-(substituierte amino)-8-(phenyl oder substituierte phenyl)-3h,6h-1,4,5a,8atetraazaacenaphthylen-3-one. - Google Patents

5-(substituierte amino)-8-(phenyl oder substituierte phenyl)-3h,6h-1,4,5a,8atetraazaacenaphthylen-3-one.

Info

Publication number
ATE99686T1
ATE99686T1 AT89100657T AT89100657T ATE99686T1 AT E99686 T1 ATE99686 T1 AT E99686T1 AT 89100657 T AT89100657 T AT 89100657T AT 89100657 T AT89100657 T AT 89100657T AT E99686 T1 ATE99686 T1 AT E99686T1
Authority
AT
Austria
Prior art keywords
phenyl
substituted
amino
substituted amino
substituted phenyl
Prior art date
Application number
AT89100657T
Other languages
English (en)
Inventor
Joseph William Epstein
Jeremy Ian Levin
Shin Shyong Tseng
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ATE99686T1 publication Critical patent/ATE99686T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT89100657T 1988-02-22 1989-01-16 5-(substituierte amino)-8-(phenyl oder substituierte phenyl)-3h,6h-1,4,5a,8atetraazaacenaphthylen-3-one. ATE99686T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15844888A 1988-02-22 1988-02-22
EP89100657A EP0329940B1 (de) 1988-02-22 1989-01-16 5-(Substituierte Amino)-8-(phenyl oder substituierte phenyl)-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one

Publications (1)

Publication Number Publication Date
ATE99686T1 true ATE99686T1 (de) 1994-01-15

Family

ID=22568168

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89100657T ATE99686T1 (de) 1988-02-22 1989-01-16 5-(substituierte amino)-8-(phenyl oder substituierte phenyl)-3h,6h-1,4,5a,8atetraazaacenaphthylen-3-one.

Country Status (23)

Country Link
EP (1) EP0329940B1 (de)
JP (1) JP2641556B2 (de)
KR (1) KR970009226B1 (de)
AR (1) AR247211A1 (de)
AT (1) ATE99686T1 (de)
AU (1) AU611769B2 (de)
CA (1) CA1329594C (de)
CZ (1) CZ284273B6 (de)
DD (1) DD283624A5 (de)
DE (1) DE68911951T2 (de)
DK (1) DK172397B1 (de)
ES (1) ES2061739T3 (de)
FI (1) FI89922C (de)
HU (1) HU203554B (de)
IE (1) IE64147B1 (de)
IL (1) IL88974A (de)
NO (1) NO169589C (de)
NZ (1) NZ228009A (de)
PH (1) PH26358A (de)
PL (1) PL158865B1 (de)
PT (1) PT89766B (de)
SK (1) SK105589A3 (de)
ZA (1) ZA891310B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013737A (en) * 1988-02-22 1991-05-07 American Cyanamid Company 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones
EP0562236A1 (de) * 1992-03-26 1993-09-29 American Cyanamid Company Verfahren zur Synthese von 5-((substituierte)-Amino)-8-(Phenyl oder substituierte Phenyl)-3H,6H-1,4,5a,8a-Tetraazaacenaphthylen-3-Onen
EP0957918A1 (de) * 1996-12-19 1999-11-24 American Cyanamid Company Verfahren zur behandlung oder unterdrückung von neutropenie

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
US4576943A (en) * 1984-10-09 1986-03-18 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines
EP0264773A1 (de) * 1986-10-16 1988-04-27 American Cyanamid Company 4,5-Dihydro- und 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidine

Also Published As

Publication number Publication date
HUT51626A (en) 1990-05-28
AU3017289A (en) 1989-08-24
FI89922C (fi) 1993-12-10
DK79589A (da) 1989-08-23
DD283624A5 (de) 1990-10-17
IL88974A0 (en) 1989-08-15
JPH01249774A (ja) 1989-10-05
CZ284273B6 (cs) 1998-10-14
IE890543L (en) 1989-08-22
EP0329940B1 (de) 1994-01-05
AR247211A1 (es) 1994-11-30
CA1329594C (en) 1994-05-17
ES2061739T3 (es) 1994-12-16
IE64147B1 (en) 1995-07-12
FI89922B (fi) 1993-08-31
FI890826A0 (fi) 1989-02-21
SK279319B6 (sk) 1998-09-09
HU203554B (en) 1991-08-28
NZ228009A (en) 1991-09-25
NO890724D0 (no) 1989-02-21
PT89766B (pt) 1994-03-31
PL277837A1 (en) 1989-11-13
ZA891310B (en) 1989-11-29
IL88974A (en) 1993-03-15
DE68911951T2 (de) 1994-06-01
SK105589A3 (en) 1998-09-09
CZ105589A3 (cs) 1998-07-15
NO169589B (no) 1992-04-06
PT89766A (pt) 1989-10-04
DE68911951D1 (de) 1994-02-17
DK79589D0 (da) 1989-02-21
JP2641556B2 (ja) 1997-08-13
EP0329940A1 (de) 1989-08-30
PH26358A (en) 1992-04-29
NO169589C (no) 1992-07-15
FI890826A (fi) 1989-08-23
PL158865B1 (pl) 1992-10-30
AU611769B2 (en) 1991-06-20
NO890724L (no) 1989-08-23
KR970009226B1 (en) 1997-06-09
KR890013022A (ko) 1989-09-20
DK172397B1 (da) 1998-05-18

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