DD281602A5 - Verfahren zur herstellung von 3,4-dihydro-2-alkyl-3-oxo-n-aryl-2-h-(1)benzothieno-(3,2,-e)-1,2-thiazin-4-carboxamid-1,1-dioxiden - Google Patents

Verfahren zur herstellung von 3,4-dihydro-2-alkyl-3-oxo-n-aryl-2-h-(1)benzothieno-(3,2,-e)-1,2-thiazin-4-carboxamid-1,1-dioxiden Download PDF

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Publication number
DD281602A5
DD281602A5 DD88316546A DD31654688A DD281602A5 DD 281602 A5 DD281602 A5 DD 281602A5 DD 88316546 A DD88316546 A DD 88316546A DD 31654688 A DD31654688 A DD 31654688A DD 281602 A5 DD281602 A5 DD 281602A5
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DD
German Democratic Republic
Prior art keywords
formula
compound
alkyl
methyl
hydrogen
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Application number
DD88316546A
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German (de)
English (en)
Inventor
Anthony Marfat
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Publication of DD281602A5 publication Critical patent/DD281602A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DD88316546A 1987-06-10 1988-06-08 Verfahren zur herstellung von 3,4-dihydro-2-alkyl-3-oxo-n-aryl-2-h-(1)benzothieno-(3,2,-e)-1,2-thiazin-4-carboxamid-1,1-dioxiden DD281602A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1987/001357 WO1988009793A1 (en) 1987-06-10 1987-06-10 3,4-DIHYDRO-2-ALKYL-3-OXO-N-ARYL-2H-[1]BENZOTHIENO[3,2-e]-1,2-THIAZINE-4-CARBOXAMIDE-1,1-DIOXIDES
EP88304975A EP0294994B1 (en) 1987-06-10 1988-06-01 3-4-Dihydro-2-alkyl-3-oxo-N-aryl-2H-[1]benzothieno[3,2-el]-1,2-thiazine-4-carboxamide-1,1-dioxides

Publications (1)

Publication Number Publication Date
DD281602A5 true DD281602A5 (de) 1990-08-15

Family

ID=55448100

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88316546A DD281602A5 (de) 1987-06-10 1988-06-08 Verfahren zur herstellung von 3,4-dihydro-2-alkyl-3-oxo-n-aryl-2-h-(1)benzothieno-(3,2,-e)-1,2-thiazin-4-carboxamid-1,1-dioxiden

Country Status (28)

Country Link
US (1) US4914101A (no)
EP (1) EP0294994B1 (no)
JP (1) JPH078874B2 (no)
KR (1) KR900006758B1 (no)
CN (1) CN1019576B (no)
AT (1) ATE105561T1 (no)
AU (1) AU593743B2 (no)
CA (1) CA1300625C (no)
CZ (1) CZ281857B6 (no)
DD (1) DD281602A5 (no)
DE (1) DE3889497T2 (no)
DK (1) DK313388A (no)
EG (1) EG18525A (no)
ES (1) ES2051846T3 (no)
FI (1) FI89802C (no)
HU (1) HU203762B (no)
IE (1) IE63214B1 (no)
IL (1) IL86602A (no)
MX (1) MX174093B (no)
MY (1) MY103572A (no)
NO (2) NO176277C (no)
NZ (1) NZ224956A (no)
PH (1) PH25187A (no)
PL (1) PL158994B1 (no)
PT (1) PT87678B (no)
WO (1) WO1988009793A1 (no)
YU (1) YU46767B (no)
ZA (1) ZA884115B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991007970A1 (en) * 1989-11-30 1991-06-13 Nippon Hypox Laboratories Incorporated Medicine containing thiazine dioxide derivative
US6340659B1 (en) 1995-12-13 2002-01-22 The Lubrizol Corporation Metal salts of lactones as lubricant additives
JP4250344B2 (ja) 2001-01-29 2009-04-08 インターナショナル・ビジネス・マシーンズ・コーポレーション ワークフローシステム、ワークフローサーバ、および記憶媒体
US8741299B2 (en) * 2011-06-20 2014-06-03 The Feinstein Institute For Medical Research Method for treating pathologies associated with hypoxia using MIF inhibitors
US9666805B2 (en) * 2014-11-25 2017-05-30 Northwestern University Bithiophene sulfonamide-based molecular and polymeric semiconductors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
CA1066711A (en) * 1974-08-26 1979-11-20 Hoffmann-La Roche Limited Thiophene derivatives
LU78009A1 (de) * 1977-08-22 1979-05-23 Hoffmann La Roche Verfahren zur herstellung von thiazinderivaten
AU518216B2 (en) * 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
DE2838377A1 (de) * 1978-09-02 1980-03-20 Thomae Gmbh Dr K Neue 4-hydroxy-2h eckige klammer auf 1 eckige klammer zu benzothieno eckige klammer auf 2,3-e eckige klammer zu -1,2- thiazin-3-carboxamid-1,1-dioxide sowie deren salze, deren verwendung und verfahren zu ihrer herstellung
ZA803401B (en) * 1979-06-13 1981-05-27 Hoffmann La Roche Thiazine derivatives
AU5811280A (en) * 1979-06-13 1980-12-18 F. Hoffmann-La Roche Ag Thiazine derivatives

Also Published As

Publication number Publication date
JPH078874B2 (ja) 1995-02-01
HU203762B (en) 1991-09-30
FI890620A (fi) 1989-02-09
DK313388A (da) 1988-12-11
IL86602A (en) 1992-06-21
NO922636L (no) 1989-02-08
MX11827A (es) 1993-04-01
CN1019576B (zh) 1992-12-23
DE3889497D1 (de) 1994-06-16
NO890531D0 (no) 1989-02-08
IE63214B1 (en) 1995-04-05
YU46767B (sh) 1994-05-10
KR890000500A (ko) 1989-03-15
IE881733L (en) 1988-12-10
DE3889497T2 (de) 1994-08-25
AU593743B2 (en) 1990-02-15
HUT54376A (en) 1991-02-28
PT87678A (pt) 1988-07-01
EG18525A (en) 1994-04-30
FI890620A0 (fi) 1989-02-09
NO890531L (no) 1989-02-08
CA1300625C (en) 1992-05-12
NZ224956A (en) 1990-07-26
CZ392588A3 (en) 1996-11-13
US4914101A (en) 1990-04-03
NO176277B (no) 1994-11-28
YU111988A (en) 1989-12-31
CZ281857B6 (cs) 1997-03-12
KR900006758B1 (ko) 1990-09-20
NO922636D0 (no) 1992-07-03
PT87678B (pt) 1992-10-30
FI89802C (fi) 1993-11-25
ATE105561T1 (de) 1994-05-15
ES2051846T3 (es) 1994-07-01
AU1753588A (en) 1988-12-15
CN88103539A (zh) 1988-12-28
PL272928A1 (en) 1989-07-10
WO1988009793A1 (en) 1988-12-15
FI89802B (fi) 1993-08-13
ZA884115B (en) 1990-02-28
MY103572A (en) 1993-08-28
PL158994B1 (pl) 1992-10-30
IL86602A0 (en) 1988-11-30
NO176277C (no) 1995-03-08
EP0294994A1 (en) 1988-12-14
MX174093B (es) 1994-04-21
JPS6413093A (en) 1989-01-17
EP0294994B1 (en) 1994-05-11
DK313388D0 (da) 1988-06-09
PH25187A (en) 1991-03-27

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