DD259858A5 - Verfahren zur herstellung von kristallinem torasemid der modifikation i - Google Patents
Verfahren zur herstellung von kristallinem torasemid der modifikation i Download PDFInfo
- Publication number
- DD259858A5 DD259858A5 DD86293655A DD29365586A DD259858A5 DD 259858 A5 DD259858 A5 DD 259858A5 DD 86293655 A DD86293655 A DD 86293655A DD 29365586 A DD29365586 A DD 29365586A DD 259858 A5 DD259858 A5 DD 259858A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- modification
- torasemide
- rearrangement
- water
- melting point
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19853529529 DE3529529A1 (de) | 1985-08-17 | 1985-08-17 | Verfahren zur herstellung einer stabilen modifikation von torasemid |
Publications (1)
Publication Number | Publication Date |
---|---|
DD259858A5 true DD259858A5 (de) | 1988-09-07 |
Family
ID=6278766
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD86293655A DD259858A5 (de) | 1985-08-17 | 1986-08-14 | Verfahren zur herstellung von kristallinem torasemid der modifikation i |
Country Status (25)
Country | Link |
---|---|
US (4) | US4743693A (xx) |
EP (1) | EP0212537B1 (xx) |
JP (2) | JPS6245576A (xx) |
KR (1) | KR930009818B1 (xx) |
AU (1) | AU573454B2 (xx) |
CA (1) | CA1307277C (xx) |
CS (2) | CS259891B2 (xx) |
DD (1) | DD259858A5 (xx) |
DE (2) | DE3529529A1 (xx) |
DK (1) | DK162518C (xx) |
ES (1) | ES2001522A6 (xx) |
FI (1) | FI82189C (xx) |
GR (1) | GR862139B (xx) |
HK (1) | HK59994A (xx) |
HU (1) | HU195778B (xx) |
IE (1) | IE59237B1 (xx) |
IL (1) | IL79672A (xx) |
LT (1) | LT3596B (xx) |
NO (1) | NO170079C (xx) |
NZ (1) | NZ217172A (xx) |
PL (1) | PL146086B1 (xx) |
PT (1) | PT83186B (xx) |
SU (1) | SU1480766A3 (xx) |
UA (1) | UA7080A1 (xx) |
ZA (1) | ZA866151B (xx) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3623620A1 (de) * | 1986-07-12 | 1988-01-21 | Boehringer Mannheim Gmbh | Spritzfertige, waessrige, alkalische injektionsloesungen von torasemid und verfahren zu ihrer herstellung |
US5166162A (en) * | 1990-03-02 | 1992-11-24 | Adir Et Compagnie | Pyridylsulfonylurea and pyridylsulfonylthiourea compounds |
JP3586471B2 (ja) * | 1991-06-25 | 2004-11-10 | 三菱ウェルファーマ株式会社 | トラセミド含有医薬組成物 |
HRP980532B1 (en) * | 1998-10-02 | 2005-06-30 | Pliva | Novel crystalline torasemide modification |
US6166045A (en) | 1998-06-02 | 2000-12-26 | Roche Diagnostics Gmbh | Torasemide of modification III |
US5914336A (en) | 1998-06-02 | 1999-06-22 | Boehringer Mannheim Gmbh | Method of controlling the serum solubility of orally administered torasemide and composition relating thereto |
US20030026835A1 (en) * | 1999-02-15 | 2003-02-06 | Sumitomo Pharmaceuticals Company Limited | Tablets disintegrating rapidly in the oral cavity |
KR20020025217A (ko) * | 1999-08-11 | 2002-04-03 | 추후보정 | 토르세미드 동질이상 |
HUP0600143A2 (en) * | 2000-02-17 | 2006-10-28 | Teva Pharma | A stable pharmaceutical formulation comprising torsemide modification ii |
HRP20000162B1 (en) * | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
PL370039A1 (en) | 2000-03-20 | 2005-05-16 | Teva Pharmaceutical Industries Ltd. | Novel processes for preparing torsemide intermediate |
HRP20000765A2 (en) * | 2000-11-10 | 2002-06-30 | Pliva D D | Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release |
US20030022921A1 (en) * | 2001-02-21 | 2003-01-30 | Minutza Leibovici | Stable pharmaceutical formulation comprising torsemide modification II |
IN192178B (xx) * | 2001-08-03 | 2004-03-06 | Ranbaxy Lab | |
AU2003217676B2 (en) | 2002-02-22 | 2009-06-11 | Takeda Pharmaceutical Company Limited | Active agent delivery systems and methods for protecting and administering active agents |
ITMI20020639A1 (it) * | 2002-03-27 | 2003-09-29 | Cosma S P A | Composizioni farmaceutiche comprendenti come principio attivo 1-isopropil-3°(4-m-toluidino-3-pridil)sulfonil!-urea |
HRP20020603B1 (en) * | 2002-07-19 | 2008-11-30 | Pliva D.D. | New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide |
KR20050075424A (ko) * | 2002-11-18 | 2005-07-20 | 테바 파마슈티컬 인더스트리즈 리미티드 | 500 ppm을 초과하고 약 3,000 ppm 이하인 물과 200ppm을 초과하고 약 5,000 ppm 이하인 알콜을함유하는 안정한 란소프라졸 |
WO2004072061A1 (en) * | 2003-02-05 | 2004-08-26 | Teva Pharmaceutical Industries Ltd. | Method of stabilizing lansoprazole |
ES2244324B1 (es) * | 2004-03-25 | 2006-11-16 | Ferrer Internacional, S.A. | Composiciones diureticas de liberacion prolongada. |
AT500576B1 (de) * | 2004-07-28 | 2006-11-15 | Sanochemia Pharmazeutika Ag | Verfahren zur reindarstellung von kristallformen von torsemid |
US10178893B1 (en) * | 2013-06-14 | 2019-01-15 | Scott Bradley Baker | Shoe |
FR3018688A1 (fr) * | 2014-03-19 | 2015-09-25 | Virbac | Utilisation de torasemide a faible dose dans une composition veterinaire |
EP3031471A1 (en) | 2014-12-12 | 2016-06-15 | Ceva Sante Animale | Veterinary composition for the treatment of pulmonary edema associated with heart failure in domestic animals |
DK3173075T3 (en) * | 2015-11-27 | 2019-01-21 | Accupharma Spolka Z Ograniczona Odpowiedzialnoscia | PHARMACEUTICAL COMBINATION PREPARATION OF ACE INHIBITOR AND LOOPDIURETIC |
CN115417810B (zh) * | 2022-09-22 | 2023-10-10 | 南京正科医药股份有限公司 | 一种托拉塞米晶型ⅰ的精制方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US30633A (en) * | 1860-11-13 | Improvement in fire-escapes | ||
GB1477664A (en) * | 1974-04-17 | 1977-06-22 | Christiaens Sa A | Pyridine derivatives |
GB1593609A (en) * | 1978-01-31 | 1981-07-22 | Christiaens Sa A | Pyridine sulfonamides |
LU85193A1 (fr) * | 1984-01-31 | 1985-09-12 | Christiaens Sa A | Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation |
-
1985
- 1985-08-17 DE DE19853529529 patent/DE3529529A1/de active Granted
-
1986
- 1986-08-10 IL IL79672A patent/IL79672A/xx not_active IP Right Cessation
- 1986-08-11 CS CS865945A patent/CS259891B2/cs not_active IP Right Cessation
- 1986-08-11 AU AU61055/86A patent/AU573454B2/en not_active Expired
- 1986-08-11 US US06/895,355 patent/US4743693A/en not_active Ceased
- 1986-08-11 CA CA000515676A patent/CA1307277C/en not_active Expired - Lifetime
- 1986-08-12 NZ NZ217172A patent/NZ217172A/xx unknown
- 1986-08-12 DE DE8686111118T patent/DE3667970D1/de not_active Expired - Lifetime
- 1986-08-12 PT PT83186A patent/PT83186B/pt unknown
- 1986-08-12 EP EP86111118A patent/EP0212537B1/de not_active Expired - Lifetime
- 1986-08-13 DK DK385586A patent/DK162518C/da not_active IP Right Cessation
- 1986-08-13 IE IE217986A patent/IE59237B1/en not_active IP Right Cessation
- 1986-08-14 GR GR862139A patent/GR862139B/el unknown
- 1986-08-14 DD DD86293655A patent/DD259858A5/de not_active IP Right Cessation
- 1986-08-14 ES ES8601131A patent/ES2001522A6/es not_active Expired
- 1986-08-14 KR KR1019860006689A patent/KR930009818B1/ko not_active IP Right Cessation
- 1986-08-15 NO NO863305A patent/NO170079C/no not_active IP Right Cessation
- 1986-08-15 ZA ZA866151A patent/ZA866151B/xx unknown
- 1986-08-15 SU SU864027953A patent/SU1480766A3/ru active
- 1986-08-15 PL PL1986261052A patent/PL146086B1/pl unknown
- 1986-08-15 UA UA4027953A patent/UA7080A1/uk unknown
- 1986-08-15 HU HU863598A patent/HU195778B/hu unknown
- 1986-08-15 FI FI863305A patent/FI82189C/fi not_active IP Right Cessation
- 1986-08-18 JP JP61191789A patent/JPS6245576A/ja active Granted
-
1987
- 1987-10-20 US US07/111,439 patent/US4822807A/en not_active Ceased
-
1989
- 1989-10-27 JP JP1278800A patent/JPH0643400B2/ja not_active Expired - Lifetime
-
1991
- 1991-12-31 CS CS914199A patent/CS419991A3/cs unknown
-
1992
- 1992-12-03 US US07/985,053 patent/USRE34580E/en not_active Expired - Lifetime
-
1993
- 1993-04-08 US US08/043,631 patent/USRE34672E/en not_active Expired - Lifetime
- 1993-08-27 LT LTIP898A patent/LT3596B/lt not_active IP Right Cessation
-
1994
- 1994-06-23 HK HK59994A patent/HK59994A/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0212537B1 (de) | Verfahren zur Herstellung einer stabilen Modifikation von Torasemid sowie Arzneimittel enthaltend Torasemid | |
DE3143219C2 (xx) | ||
WO2011107295A1 (de) | Kristalline formen zu 5-amino-2,3-dihydrophthalazin-1,4-dion natriumsalz, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung | |
EP0078430A2 (de) | Verfahren zur Herstellung von festen, schnellfreisetzenden Arzneizubereitungen mit Dihydropyridinen | |
DE69922977T2 (de) | Neue Kristallmodifikation von Torasemid | |
DE2326880C2 (de) | 7-(D- α-Amino-1,4-cyclohexadien-1-ylacetamido)-desacetoxycephalosporansäuredihydrat | |
DE69001111T2 (de) | Antikrebs-zusammensetzung. | |
DE3443065C2 (xx) | ||
DE3139554C2 (xx) | ||
DE60222643T2 (de) | Kristallines isoxazol-derivat und medizinisches präparat daraus | |
DE2535228A1 (de) | Mikrokristallin 3-(alpha-acetonylbenzyl)-umbelliferon (rattengift), dessen zusammensetzung, verfahren der herstellung und verwendung | |
DE69001004T2 (de) | Zusammensetzung gegen leberkrankheiten. | |
EP0126999B1 (de) | Verfahren zur Herstellung von sphärisch-kristallinem 5-(Hydroxy)-tetracyclinhydrochlorid (Oxytetracyclinhydrochlorid) | |
DE2943167C2 (xx) | ||
DE69307894T2 (de) | Ng-monomethyl-l-arginin-hydrochlorid-derivate und verfahren zu deren herstellung | |
DD242405A5 (de) | Verfahren zur herstellung einer neuen kristallinen form eines benzothlazindioxid-salzes | |
EP0253293B1 (de) | Neue Guanidiniumasparaginate | |
EP0214528A2 (de) | (+)-6-Chlor-5,10-dihydro-5-[(1-methyl-4-piperidinyl)acetyl]-11H-dibenzo[b,e][1,4]diazepin-11-on, seine Isolierung und Verwendung als Arzneimittel | |
EP0061654B1 (de) | Vincamin-cyclamat, Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel | |
DE69734460T2 (de) | Verfahren zur kristallisierung eines tetrahydropyridinderivates und die so erhaltenen kristallinen formen | |
DE69202594T2 (de) | Zusammensetzung gegen Katarakt. | |
DE69005993T2 (de) | Verfahren zur Herstellung eines Ranitidin-Harz-Absorbates. | |
DE69724999T2 (de) | Mikropartikularform eines tetrahydropyridinderivates | |
EP0362731A2 (de) | Verfahren zur Herstellung von Arzneimittelwirkstoff-Partikeln mit verbesserten Fliess-, Lager- und Formulierungseigenschaften sowie Arzneimittel, die diese Arzneimittelwirkstoff-Partikeln enthalten | |
DE2256538C2 (de) | Probenecidsalz des Pivaloyloxymethylesters von D-(-)-α-Aminobenzylpenicillin, seine Herstellung und diese enthaltende pharmazeutische Mittel |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ENJ | Ceased due to non-payment of renewal fee |