DD238329A5 - Verfahren zur verbesserung der chemischen stabilitaet von loesungen von piroxicam - Google Patents

Verfahren zur verbesserung der chemischen stabilitaet von loesungen von piroxicam Download PDF

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Publication number
DD238329A5
DD238329A5 DD85281570A DD28157085A DD238329A5 DD 238329 A5 DD238329 A5 DD 238329A5 DD 85281570 A DD85281570 A DD 85281570A DD 28157085 A DD28157085 A DD 28157085A DD 238329 A5 DD238329 A5 DD 238329A5
Authority
DD
German Democratic Republic
Prior art keywords
piroxicam
methylglucamine
solutions
solvent
chemical stability
Prior art date
Application number
DD85281570A
Other languages
German (de)
English (en)
Inventor
Walter Fries
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������@�������@���Kk�� filed Critical �������@�������@���Kk��
Publication of DD238329A5 publication Critical patent/DD238329A5/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Finger-Pressure Massage (AREA)
DD85281570A 1984-10-10 1985-10-09 Verfahren zur verbesserung der chemischen stabilitaet von loesungen von piroxicam DD238329A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843437232 DE3437232A1 (de) 1984-10-10 1984-10-10 Stabilisierte injektionsloesungen von piroxicam

Publications (1)

Publication Number Publication Date
DD238329A5 true DD238329A5 (de) 1986-08-20

Family

ID=6247603

Family Applications (1)

Application Number Title Priority Date Filing Date
DD85281570A DD238329A5 (de) 1984-10-10 1985-10-09 Verfahren zur verbesserung der chemischen stabilitaet von loesungen von piroxicam

Country Status (22)

Country Link
US (1) US4628053A (enExample)
EP (1) EP0177870B1 (enExample)
JP (1) JPS6191116A (enExample)
KR (1) KR890001001B1 (enExample)
CN (1) CN85107838B (enExample)
AT (1) ATE62416T1 (enExample)
AU (1) AU557184B2 (enExample)
CA (1) CA1251734A (enExample)
DD (1) DD238329A5 (enExample)
DE (2) DE3437232A1 (enExample)
DK (1) DK165901C (enExample)
FI (1) FI84315C (enExample)
GR (1) GR852439B (enExample)
HU (1) HU195111B (enExample)
IE (1) IE58267B1 (enExample)
IL (1) IL76624A0 (enExample)
NO (1) NO166687C (enExample)
NZ (1) NZ213758A (enExample)
PH (1) PH23058A (enExample)
PT (1) PT81264B (enExample)
SU (1) SU1482509A3 (enExample)
ZA (1) ZA857783B (enExample)

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FR2545910B1 (fr) * 1983-05-11 1988-07-22 Valeo Dispositif pour ameliorer l'efficacite d'un echangeur de chaleur dans un boitier d'une installation de climatisation, et boitier de cette installation
IT1196307B (it) * 1984-10-22 1988-11-16 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam monoidrato
US5807568A (en) * 1994-12-27 1998-09-15 Mcneil-Ppc, Inc. Enhanced delivery of topical compositions containing flurbiprofen
IT1283252B1 (it) * 1996-03-15 1998-04-16 Pulitzer Italiana Soluzioni di piroxicam iniettabili per via parenterale
WO1998001138A1 (fr) * 1996-07-04 1998-01-15 Nippon Kayaku Kabushiki Kaisha Injections de succinate sodique de methylprednisolone
US6136799A (en) * 1998-04-08 2000-10-24 Abbott Laboratories Cosolvent formulations
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
US8314124B2 (en) 2004-02-06 2012-11-20 Active Biotech Ab Crystalline salts of quinoline compounds and methods for preparing them
EP1568369A1 (en) * 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
DE102004021281A1 (de) * 2004-04-29 2005-11-24 Boehringer Ingelheim Vetmedica Gmbh Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin
DE102004030409A1 (de) * 2004-06-23 2006-01-26 Boehringer Ingelheim Vetmedica Gmbh Neue Verwendung von Meloxicam in der Veterinärmedizin
NZ567627A (en) * 2005-09-30 2011-08-26 Boehringer Ingelheim Vetmed Granulation process for making a divisible tablet containing meloxicam
DK1937642T3 (en) * 2005-10-19 2014-12-15 Teva Pharma Crystals of sodium laquinimod and the process for its preparation
EA018031B1 (ru) * 2006-06-12 2013-05-30 Тева Фармасьютикал Индастриз, Лтд. Стабильные препараты лаквинимода
PT2682120T (pt) 2007-12-20 2016-11-07 Teva Pharma Preparações de laquinimod estáveis
WO2010028015A2 (en) * 2008-09-03 2010-03-11 Auspex Pharmaceuticals, Inc 2-oxo-1,2-dihydro-quinoline modulators of immune function
JP5359333B2 (ja) * 2009-02-05 2013-12-04 ゼリア新薬工業株式会社 コロソリン酸含有水性液剤
JP5882208B2 (ja) * 2009-07-30 2016-03-09 テバ ファーマシューティカル インダストリーズ リミティド ラキニモドによるクローン病の治療
AU2010282948C1 (en) * 2009-08-10 2017-03-02 Active Biotech, Ab Treatment of BDNF-related disorders using laquinimod
WO2011046853A1 (en) 2009-10-12 2011-04-21 Boehringer Ingelheim Vetmedica Gmbh Containers for compositions comprising meloxicam
US20110218191A1 (en) * 2010-03-03 2011-09-08 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the long term-treatment of kidney disorders in cats
MX2012010077A (es) 2010-03-03 2012-09-12 Boehringer Ingelheim Vetmed Uso de meloxicam para el tratamiento a largo plazo de trastornos musculoesqueleticos en gatos.
DE102010014290A1 (de) * 2010-04-08 2011-10-13 Hans Otto Meyer zu Spelbrink Mittel zur prophylaktischen und therapeutischen Behandlung von Herpes-Infektionen
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
JP2014530821A (ja) 2011-10-12 2014-11-20 テバ ファーマシューティカル インダストリーズ リミティド ラキニモドおよびフィンゴリモドを組み合わせた多発性硬化症の治療
WO2013116657A1 (en) 2012-02-03 2013-08-08 Teva Pharmaceutical Industries Ltd. USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNFα THERAPY
TW201400117A (zh) 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
MX2015005632A (es) 2012-11-07 2016-02-05 Teva Pharma Sales de amina de laquinimod.
WO2014153145A2 (en) 2013-03-14 2014-09-25 Teva Pharmaceutical Industries Ltd. Crystals of laquinimod sodium and improved process for the manufacture thereof
KR101749425B1 (ko) * 2015-11-17 2017-06-22 연세대학교 산학협력단 난용성 약물의 서방형 제제
ES2984268T3 (es) * 2017-08-09 2024-10-29 Dechra Veterinary Products Llc Formulaciones terapéuticas que comprenden un inhibidor de la COX-2 y usos de las mismas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629650A (enExample) * 1967-05-18 1900-01-01
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
DE2602363C2 (de) * 1976-01-22 1984-04-12 Bayer Ag, 5090 Leverkusen Wäßrige, injizierbare Niclofolan- Formulierungen
DE2756113A1 (de) * 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE3217315C2 (de) * 1982-05-08 1986-05-22 Gödecke AG, 1000 Berlin Arzneimittelzubereitungen mit einem Gehalt an Oxicam-Derivaten
AT376879B (de) * 1982-10-27 1985-01-10 Gerot Pharmazeutika Verfahren zur herstellung einer injektionsloesung

Also Published As

Publication number Publication date
KR890001001B1 (ko) 1989-04-18
CA1251734A (en) 1989-03-28
GR852439B (enExample) 1986-02-10
PT81264B (pt) 1988-02-17
IE852483L (en) 1986-04-10
NO166687C (no) 1991-09-04
DK461385A (da) 1986-04-11
AU557184B2 (en) 1986-12-11
PT81264A (en) 1985-11-01
FI853926A0 (fi) 1985-10-09
DK165901C (da) 1993-06-28
NO166687B (no) 1991-05-21
EP0177870B1 (de) 1991-04-10
IE58267B1 (en) 1993-08-25
DE3437232A1 (de) 1986-04-17
HUT38541A (en) 1986-06-30
SU1482509A3 (ru) 1989-05-23
EP0177870A3 (en) 1987-06-03
AU4842185A (en) 1986-04-17
IL76624A0 (en) 1986-02-28
DE3582468D1 (de) 1991-05-16
JPH03849B2 (enExample) 1991-01-09
ATE62416T1 (de) 1991-04-15
PH23058A (en) 1989-03-27
CN85107838B (zh) 1988-08-24
US4628053A (en) 1986-12-09
ZA857783B (en) 1987-05-27
JPS6191116A (ja) 1986-05-09
FI853926L (fi) 1986-04-11
KR860003013A (ko) 1986-05-19
EP0177870A2 (de) 1986-04-16
CN85107838A (zh) 1986-07-09
DK165901B (da) 1993-02-08
DK461385D0 (da) 1985-10-09
HU195111B (en) 1988-04-28
NO854011L (no) 1986-04-11
NZ213758A (en) 1988-07-28
FI84315C (fi) 1991-11-25
FI84315B (fi) 1991-08-15

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