ATE62416T1 - Stabilisierte injektionsloesungen von piroxicam. - Google Patents
Stabilisierte injektionsloesungen von piroxicam.Info
- Publication number
- ATE62416T1 ATE62416T1 AT85112378T AT85112378T ATE62416T1 AT E62416 T1 ATE62416 T1 AT E62416T1 AT 85112378 T AT85112378 T AT 85112378T AT 85112378 T AT85112378 T AT 85112378T AT E62416 T1 ATE62416 T1 AT E62416T1
- Authority
- AT
- Austria
- Prior art keywords
- piroxicam
- solutions
- injection solutions
- stabilized injection
- stabilized
- Prior art date
Links
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 title abstract 3
- 229960002702 piroxicam Drugs 0.000 title abstract 3
- 239000000243 solution Substances 0.000 title abstract 3
- 238000002347 injection Methods 0.000 title 1
- 239000007924 injection Substances 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Finger-Pressure Massage (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843437232 DE3437232A1 (de) | 1984-10-10 | 1984-10-10 | Stabilisierte injektionsloesungen von piroxicam |
| EP85112378A EP0177870B1 (de) | 1984-10-10 | 1985-09-30 | Stabilisierte Injektionslösungen von Piroxicam |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE62416T1 true ATE62416T1 (de) | 1991-04-15 |
Family
ID=6247603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85112378T ATE62416T1 (de) | 1984-10-10 | 1985-09-30 | Stabilisierte injektionsloesungen von piroxicam. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4628053A (enExample) |
| EP (1) | EP0177870B1 (enExample) |
| JP (1) | JPS6191116A (enExample) |
| KR (1) | KR890001001B1 (enExample) |
| CN (1) | CN85107838B (enExample) |
| AT (1) | ATE62416T1 (enExample) |
| AU (1) | AU557184B2 (enExample) |
| CA (1) | CA1251734A (enExample) |
| DD (1) | DD238329A5 (enExample) |
| DE (2) | DE3437232A1 (enExample) |
| DK (1) | DK165901C (enExample) |
| FI (1) | FI84315C (enExample) |
| GR (1) | GR852439B (enExample) |
| HU (1) | HU195111B (enExample) |
| IE (1) | IE58267B1 (enExample) |
| IL (1) | IL76624A0 (enExample) |
| NO (1) | NO166687C (enExample) |
| NZ (1) | NZ213758A (enExample) |
| PH (1) | PH23058A (enExample) |
| PT (1) | PT81264B (enExample) |
| SU (1) | SU1482509A3 (enExample) |
| ZA (1) | ZA857783B (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2545910B1 (fr) * | 1983-05-11 | 1988-07-22 | Valeo | Dispositif pour ameliorer l'efficacite d'un echangeur de chaleur dans un boitier d'une installation de climatisation, et boitier de cette installation |
| IT1196307B (it) * | 1984-10-22 | 1988-11-16 | Chiesi Farma Spa | Formulazioni farmaceutiche acquose di piroxicam monoidrato |
| US5807568A (en) * | 1994-12-27 | 1998-09-15 | Mcneil-Ppc, Inc. | Enhanced delivery of topical compositions containing flurbiprofen |
| IT1283252B1 (it) * | 1996-03-15 | 1998-04-16 | Pulitzer Italiana | Soluzioni di piroxicam iniettabili per via parenterale |
| WO1998001138A1 (fr) * | 1996-07-04 | 1998-01-15 | Nippon Kayaku Kabushiki Kaisha | Injections de succinate sodique de methylprednisolone |
| US6136799A (en) * | 1998-04-08 | 2000-10-24 | Abbott Laboratories | Cosolvent formulations |
| US20020035107A1 (en) | 2000-06-20 | 2002-03-21 | Stefan Henke | Highly concentrated stable meloxicam solutions |
| DE10030345A1 (de) * | 2000-06-20 | 2002-01-10 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen |
| DE10161077A1 (de) | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
| US8992980B2 (en) | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
| US8314124B2 (en) | 2004-02-06 | 2012-11-20 | Active Biotech Ab | Crystalline salts of quinoline compounds and methods for preparing them |
| EP1568369A1 (en) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
| DE102004021281A1 (de) * | 2004-04-29 | 2005-11-24 | Boehringer Ingelheim Vetmedica Gmbh | Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin |
| DE102004030409A1 (de) * | 2004-06-23 | 2006-01-26 | Boehringer Ingelheim Vetmedica Gmbh | Neue Verwendung von Meloxicam in der Veterinärmedizin |
| SG166115A1 (en) * | 2005-09-30 | 2010-11-29 | Boehringer Ingelheim Vetmed | Pharmaceutical preparation containing meloxicam |
| BRPI0617477A2 (pt) * | 2005-10-19 | 2011-07-26 | Teva Pharma | mistura de partÍculas cristalinas de laquinimod sàdica, composiÇço, processo de cristalizaÇço de laquinimod sàdica, laquinimod sàdica, e, processo para produzir uma composiÇço farmacÊutica |
| CN101466379B (zh) | 2006-06-12 | 2012-10-31 | 泰华制药工业有限公司 | 稳定的拉喹莫德的制剂 |
| WO2009082471A1 (en) * | 2007-12-20 | 2009-07-02 | Teva Pharmaceutical Industries, Ltd. | Stable laquinimod preparations |
| AU2009288108B2 (en) * | 2008-09-03 | 2013-10-17 | Teva Pharmaceutical Industries, Ltd. | 2-oxo-1,2-dihydro-quinoline modulators of immune function |
| JP5359333B2 (ja) * | 2009-02-05 | 2013-12-04 | ゼリア新薬工業株式会社 | コロソリン酸含有水性液剤 |
| BR112012002124A2 (pt) * | 2009-07-30 | 2015-09-15 | Teva Pharma | tratamento da doença de crohn com laquinimode. |
| WO2011019375A1 (en) * | 2009-08-10 | 2011-02-17 | Teva Pharmaceutical Industries Ltd. | Treatment of bdnf-related disorders using laquinimod |
| US9101529B2 (en) | 2009-10-12 | 2015-08-11 | Boehringer Ingelheim Vetmedica Gmbh | Containers for compositions comprising meloxicam |
| US20110218191A1 (en) * | 2010-03-03 | 2011-09-08 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long term-treatment of kidney disorders in cats |
| WO2011107150A1 (en) | 2010-03-03 | 2011-09-09 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats |
| DE102010014290A1 (de) * | 2010-04-08 | 2011-10-13 | Hans Otto Meyer zu Spelbrink | Mittel zur prophylaktischen und therapeutischen Behandlung von Herpes-Infektionen |
| US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
| SG11201401330YA (en) | 2011-10-12 | 2014-05-29 | Teva Pharma | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
| WO2013116657A1 (en) | 2012-02-03 | 2013-08-08 | Teva Pharmaceutical Industries Ltd. | USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNFα THERAPY |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| EA201590788A1 (ru) | 2012-11-07 | 2015-12-30 | Тева Фармасьютикал Индастриз Лтд. | Аминные соли лахинимода |
| JP2016514162A (ja) | 2013-03-14 | 2016-05-19 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドナトリウムの結晶およびその製造のための改善された方法 |
| KR101749425B1 (ko) * | 2015-11-17 | 2017-06-22 | 연세대학교 산학협력단 | 난용성 약물의 서방형 제제 |
| US20190142789A1 (en) * | 2017-08-09 | 2019-05-16 | Piedmont Animal Health, Llc | Therapeutic formulations and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE629650A (enExample) * | 1967-05-18 | 1900-01-01 | ||
| US3591584A (en) * | 1968-08-27 | 1971-07-06 | Pfizer | Benzothiazine dioxides |
| DE2602363C2 (de) * | 1976-01-22 | 1984-04-12 | Bayer Ag, 5090 Leverkusen | Wäßrige, injizierbare Niclofolan- Formulierungen |
| DE2756113A1 (de) * | 1977-12-16 | 1979-06-21 | Thomae Gmbh Dr K | Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| DE3217315C2 (de) * | 1982-05-08 | 1986-05-22 | Gödecke AG, 1000 Berlin | Arzneimittelzubereitungen mit einem Gehalt an Oxicam-Derivaten |
| AT376879B (de) * | 1982-10-27 | 1985-01-10 | Gerot Pharmazeutika | Verfahren zur herstellung einer injektionsloesung |
-
1984
- 1984-10-10 DE DE19843437232 patent/DE3437232A1/de not_active Ceased
-
1985
- 1985-09-30 EP EP85112378A patent/EP0177870B1/de not_active Expired - Lifetime
- 1985-09-30 DE DE8585112378T patent/DE3582468D1/de not_active Expired - Fee Related
- 1985-09-30 AT AT85112378T patent/ATE62416T1/de not_active IP Right Cessation
- 1985-10-07 US US06/784,903 patent/US4628053A/en not_active Expired - Fee Related
- 1985-10-08 PT PT81264A patent/PT81264B/pt not_active IP Right Cessation
- 1985-10-08 CA CA000492481A patent/CA1251734A/en not_active Expired
- 1985-10-08 KR KR1019850007399A patent/KR890001001B1/ko not_active Expired
- 1985-10-08 JP JP60224617A patent/JPS6191116A/ja active Granted
- 1985-10-08 GR GR852439A patent/GR852439B/el unknown
- 1985-10-09 IE IE248385A patent/IE58267B1/en not_active IP Right Cessation
- 1985-10-09 ZA ZA857783A patent/ZA857783B/xx unknown
- 1985-10-09 NZ NZ213758A patent/NZ213758A/xx unknown
- 1985-10-09 NO NO854011A patent/NO166687C/no unknown
- 1985-10-09 HU HU853920A patent/HU195111B/hu not_active IP Right Cessation
- 1985-10-09 DK DK461385A patent/DK165901C/da not_active IP Right Cessation
- 1985-10-09 CN CN85107838A patent/CN85107838B/zh not_active Expired
- 1985-10-09 PH PH32905A patent/PH23058A/en unknown
- 1985-10-09 DD DD85281570A patent/DD238329A5/de not_active IP Right Cessation
- 1985-10-09 AU AU48421/85A patent/AU557184B2/en not_active Ceased
- 1985-10-09 IL IL76624A patent/IL76624A0/xx not_active IP Right Cessation
- 1985-10-09 SU SU853966192A patent/SU1482509A3/ru active
- 1985-10-09 FI FI853926A patent/FI84315C/fi not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |