FR2656866B1 - Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant. - Google Patents
Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant.Info
- Publication number
- FR2656866B1 FR2656866B1 FR9000214A FR9000214A FR2656866B1 FR 2656866 B1 FR2656866 B1 FR 2656866B1 FR 9000214 A FR9000214 A FR 9000214A FR 9000214 A FR9000214 A FR 9000214A FR 2656866 B1 FR2656866 B1 FR 2656866B1
- Authority
- FR
- France
- Prior art keywords
- metalloporphyrins
- pharmaceutical composition
- composition containing
- biologically active
- active molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000004033 porphyrin derivatives Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B24—GRINDING; POLISHING
- B24B—MACHINES, DEVICES, OR PROCESSES FOR GRINDING OR POLISHING; DRESSING OR CONDITIONING OF ABRADING SURFACES; FEEDING OF GRINDING, POLISHING, OR LAPPING AGENTS
- B24B49/00—Measuring or gauging equipment for controlling the feed movement of the grinding tool or work; Arrangements of indicating or measuring equipment, e.g. for indicating the start of the grinding operation
- B24B49/003—Measuring or gauging equipment for controlling the feed movement of the grinding tool or work; Arrangements of indicating or measuring equipment, e.g. for indicating the start of the grinding operation involving acoustic means
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Acoustics & Sound (AREA)
- Mechanical Engineering (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9000214A FR2656866B1 (fr) | 1990-01-10 | 1990-01-10 | Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant. |
PCT/FR1991/000010 WO1991010667A1 (fr) | 1990-01-10 | 1991-01-09 | Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant |
EP91902981A EP0510074A1 (fr) | 1990-01-10 | 1991-01-09 | Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant |
US07/943,299 US5268371A (en) | 1990-01-10 | 1992-09-10 | Derivatives of porphyrin and metalloporphyrins optionally coupled to a biologically active molecule and pharmaceutical composition containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9000214A FR2656866B1 (fr) | 1990-01-10 | 1990-01-10 | Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant. |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2656866A1 FR2656866A1 (fr) | 1991-07-12 |
FR2656866B1 true FR2656866B1 (fr) | 1992-05-15 |
Family
ID=9392631
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9000214A Expired - Fee Related FR2656866B1 (fr) | 1990-01-10 | 1990-01-10 | Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant. |
Country Status (4)
Country | Link |
---|---|
US (1) | US5268371A (fr) |
EP (1) | EP0510074A1 (fr) |
FR (1) | FR2656866B1 (fr) |
WO (1) | WO1991010667A1 (fr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5252730A (en) * | 1992-04-10 | 1993-10-12 | Northrop Corporation | Polymer composition having intense magnetic properties and method for preparation thereof |
US5464741A (en) * | 1993-10-08 | 1995-11-07 | Henwell, Inc. | Palladium (II) octaethylporphine alpha-isothiocyanate as a phosphorescent label for immunoassays |
US6331273B1 (en) | 1995-04-25 | 2001-12-18 | Discovery Partners International | Remotely programmable matrices with memories |
US6416714B1 (en) | 1995-04-25 | 2002-07-09 | Discovery Partners International, Inc. | Remotely programmable matrices with memories |
US5874214A (en) | 1995-04-25 | 1999-02-23 | Irori | Remotely programmable matrices with memories |
US6329139B1 (en) | 1995-04-25 | 2001-12-11 | Discovery Partners International | Automated sorting system for matrices with memory |
US6017496A (en) | 1995-06-07 | 2000-01-25 | Irori | Matrices with memories and uses thereof |
US5751629A (en) | 1995-04-25 | 1998-05-12 | Irori | Remotely programmable matrices with memories |
EP1091742A4 (fr) | 1997-02-14 | 2007-05-30 | Miravant Pharm Inc | Photosensiblisant a l'indium, pour tpd |
IL126953A0 (en) | 1998-11-08 | 1999-09-22 | Yeda Res & Dev | Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives |
AU6068200A (en) * | 1999-07-01 | 2001-01-22 | University Of Utah, The | Nickel-based reagents for detecting dna and dna-protein contacts |
US7371579B1 (en) | 1999-07-01 | 2008-05-13 | The University Of Maryland | Nickel-based reagents for detecting DNA and DNA-protein contacts |
US6403788B1 (en) | 2000-07-11 | 2002-06-11 | Eukarion, Inc. | Non-genotoxic metalloporphyrins as synthetic catalytic scavengers of reactive oxygen species |
EP1367998A4 (fr) * | 2000-09-15 | 2004-03-17 | Scripps Research Inst | Procedes et compositions concernant le peroxyde d'hydrogene et la production de superoxyde par des anticorps |
US6566517B2 (en) * | 2001-06-06 | 2003-05-20 | Brookhaven Science Associates, Llc | Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy |
US7166478B2 (en) * | 2002-03-12 | 2007-01-23 | Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. | Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses |
GB2397067B (en) | 2002-12-23 | 2005-05-11 | Destiny Pharma Ltd | Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation |
US20050055487A1 (en) * | 2003-09-04 | 2005-03-10 | Toshiyuki Tanaka | Rotating docking station |
US6995260B2 (en) * | 2004-05-20 | 2006-02-07 | Brookhaven Science Associates, Llc | Carboranylporphyrins and uses thereof |
US6989443B2 (en) * | 2004-06-28 | 2006-01-24 | Brookhaven Science Associates, Llc | Carboranylporphyrins and uses thereof |
GB2415372A (en) | 2004-06-23 | 2005-12-28 | Destiny Pharma Ltd | Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent |
US8287839B2 (en) * | 2006-12-04 | 2012-10-16 | Brookhaven Science Associates, Llc | Carboranylporphyrins and uses thereof |
US8444953B2 (en) * | 2007-03-22 | 2013-05-21 | Brookhaven Science Associates, Llc | Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof |
US20080279781A1 (en) * | 2007-05-10 | 2008-11-13 | Brookhaven Science Associates, Llc | Glycosylated Carboranylporphyrins and Uses Thereof |
EP2230242B1 (fr) * | 2009-03-16 | 2013-08-14 | Johannes Kepler Universität | Synthèse des nouvelles porphyrines solubles dans l'eau méso-substituées agissant en tant qu'agents cytostatiques |
CA3028122A1 (fr) * | 2016-06-16 | 2017-12-21 | Oncoselect Therapeutics, Llc | Composes de porphyrine et compositions utiles pour le traitement du cancer |
CN108752354A (zh) * | 2018-06-11 | 2018-11-06 | 三峡大学 | 一种卟啉荧光染料的合成及其方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0127797B1 (fr) * | 1983-06-03 | 1987-06-16 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Molécules marquées pour déterminations par immunofluorescence et procédés et produits intermédiaires pour leur préparation |
GB8429845D0 (en) * | 1984-11-26 | 1985-01-03 | Efamol Ltd | Porphyrins & cancer treatment |
US4783529A (en) * | 1985-12-03 | 1988-11-08 | Research Corporation Technologies | Rapid synthesis of radiolabeled porphyrin complexes for medical application |
US4877872A (en) * | 1986-06-24 | 1989-10-31 | The University Of Toledo | Production and use of dimers of hematoporophyrin, purpurins, chlorines and purpurin- and chlorin-complexes |
US4851403A (en) * | 1987-04-21 | 1989-07-25 | Johnson Matthey, Inc. | Radiation sensitizers |
US5001230A (en) * | 1988-02-18 | 1991-03-19 | Schering Corporation | T cell activation markers |
US5109016A (en) * | 1988-05-23 | 1992-04-28 | Georgia State University Foundation, Inc. | Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions |
FR2632187B1 (fr) * | 1988-06-02 | 1990-09-14 | Centre Nat Rech Scient | Derives de metalloporphyrines, leur preparation, leur application en therapeutique et leur utilisation pour la preparation de molecules hybrides |
-
1990
- 1990-01-10 FR FR9000214A patent/FR2656866B1/fr not_active Expired - Fee Related
-
1991
- 1991-01-09 WO PCT/FR1991/000010 patent/WO1991010667A1/fr not_active Application Discontinuation
- 1991-01-09 EP EP91902981A patent/EP0510074A1/fr not_active Ceased
-
1992
- 1992-09-10 US US07/943,299 patent/US5268371A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1991010667A1 (fr) | 1991-07-25 |
FR2656866A1 (fr) | 1991-07-12 |
EP0510074A1 (fr) | 1992-10-28 |
US5268371A (en) | 1993-12-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property | ||
ST | Notification of lapse |