KR900017609A - 안정화된 칼시토닌 약학 조성물 - Google Patents
안정화된 칼시토닌 약학 조성물 Download PDFInfo
- Publication number
- KR900017609A KR900017609A KR1019900007438A KR900007438A KR900017609A KR 900017609 A KR900017609 A KR 900017609A KR 1019900007438 A KR1019900007438 A KR 1019900007438A KR 900007438 A KR900007438 A KR 900007438A KR 900017609 A KR900017609 A KR 900017609A
- Authority
- KR
- South Korea
- Prior art keywords
- calcitonin
- pharmaceutical composition
- solid
- ethylenediamine tetraacetate
- calcitonin pharmaceutical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (6)
- 칼시토닌 및 에틸렌디아민 테트라아세테이트를 함유한 수용액을 동결 건조시킴으로써 또는 칼시토닌 및 에틸렌 디아민 테트라아세테이트를 함유하는 수용액에 빈용매(poor solvent)를 가함으로써 수득되는, 치료적으로 유효한 양의 하나 이상의 칼시토닌 및 하나이상의 에틸렌디아민 테트라아세테이트를 함유하는 고체 칼시토닌 약학 조성물.
- 제1항에 있어서, 에틸렌디아민 테트라아세테이트가 디소듐 에틸렌디아민 테트라아세테이트인 고체 칼시토닌 약학 조성물.
- 제1항에 있어서, 에틸렌디아민 테트라아세테이트의 양이 칼시토닌 1IU당 0.005내지 50㎍인 고체 칼시토닌 약학 조성물.
- 제1항에 있어서, 비강투여제제의 형태인 고체 칼시토닌 약학 조성물.
- 제4항에 있어서, 비강투여제제의 형태가 경질 젤라틴 캡슐(hard gelatin capsule)인 고체 칼시토닌 약학 조성물.
- 제1항에 있어서, 주사제 또는 점안투여용의 형태인 고체 칼시토닌 약학 조성물.※ 참고사항 : 최초출원내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1127743A JP2514249B2 (ja) | 1989-05-23 | 1989-05-23 | 安定化されたカルシトニン類医薬組成物 |
JP1-127743 | 1989-05-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR900017609A true KR900017609A (ko) | 1990-12-19 |
KR950004697B1 KR950004697B1 (ko) | 1995-05-04 |
Family
ID=14967589
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019900007438A KR950004697B1 (ko) | 1989-05-23 | 1990-05-23 | 안정화된 칼시토닌 약학 조성물 |
Country Status (10)
Country | Link |
---|---|
US (1) | US5211950A (ko) |
EP (1) | EP0399781B1 (ko) |
JP (1) | JP2514249B2 (ko) |
KR (1) | KR950004697B1 (ko) |
AT (1) | ATE83667T1 (ko) |
AU (1) | AU635740B2 (ko) |
CA (1) | CA2017285C (ko) |
DE (1) | DE69000640T2 (ko) |
DK (1) | DK0399781T3 (ko) |
ES (1) | ES2053109T3 (ko) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0489217A1 (en) * | 1990-12-05 | 1992-06-10 | Dr. A. Tosi Farmaceutici S.R.L. | Calcitonin compositions for intranasal administration |
JP3179538B2 (ja) * | 1990-12-11 | 2001-06-25 | ノバルティス アクチエンゲゼルシャフト | 安定なヒトカルシトニンの水性溶液 |
IT1244500B (it) * | 1991-03-21 | 1994-07-15 | Pulitzer Italiana | Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana |
US5571788A (en) * | 1991-12-09 | 1996-11-05 | Ciba-Geigy Corporation | Stable calcitonin pharmaceutical compositions |
US5482931A (en) * | 1993-06-29 | 1996-01-09 | Ferring Ab | Stabilized pharmaceutical peptide compositions |
US5904935A (en) * | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
GB9623205D0 (en) * | 1996-11-07 | 1997-01-08 | Eurand Int | Novel pharmaceutical compositions |
EP0983769A4 (en) | 1997-04-14 | 2002-05-02 | Mitsubishi Tokyo Pharm Inc | PERMUCOSE FORMULATION |
US7402559B2 (en) * | 1999-03-24 | 2008-07-22 | Msh Pharma, Incorporated | Composition and method of treatment for urogenital conditions |
KR20010101030A (ko) * | 1999-09-17 | 2001-11-14 | 도리이 신이찌로 | 제약학적 항균 조성물 |
WO2004084859A2 (en) * | 2003-03-21 | 2004-10-07 | Nastech Pharmaceutical Company Inc. | Nasal calcitonin formulations containing chlorobutanol |
AU2003901515A0 (en) * | 2003-04-02 | 2003-04-17 | Norika Holdings | Sterilisation process for pharmaceutical product |
US7648965B2 (en) * | 2004-05-14 | 2010-01-19 | Unigene Laboratories Inc. | Method for fostering bone formation and preservation |
US9511144B2 (en) | 2013-03-14 | 2016-12-06 | The Proctor & Gamble Company | Cosmetic compositions and methods providing enhanced penetration of skin care actives |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2364659A1 (fr) * | 1976-09-21 | 1978-04-14 | Commissariat Energie Atomique | Medicament antagoniste de l'action de la gastrine et des polypeptides apparentes |
US4241051A (en) * | 1977-11-04 | 1980-12-23 | Christie Robert B | Calcitonin |
US4476116A (en) * | 1982-12-10 | 1984-10-09 | Syntex (U.S.A.) Inc. | Polypeptides/chelating agent nasal compositions having enhanced peptide absorption |
AU572815B2 (en) * | 1982-12-29 | 1988-05-19 | Armour Pharmaceutical Company | Pharmaceutical calcitonin compositions for intranasal application |
US4663309A (en) * | 1983-06-29 | 1987-05-05 | University Patents, Inc. | Novel peptide hormones with calcitonin-like activity |
JPS61267528A (ja) * | 1984-11-26 | 1986-11-27 | Yamanouchi Pharmaceut Co Ltd | 吸収促進剤を含有するカルシトニン経鼻剤 |
JPS61194034A (ja) * | 1985-02-25 | 1986-08-28 | Teijin Ltd | 経鼻投与用粉末状組成物 |
IT1204400B (it) * | 1986-06-20 | 1989-03-01 | Sclavo Spa | Composizioni farmaceutiche contenente una calcitonina |
IT1222734B (it) * | 1987-09-25 | 1990-09-12 | Scalvo S P A | Formulaziopne farmaceutiche e forme di dosaggio per la somminaistarzione rettale di calcitonina |
-
1989
- 1989-05-23 JP JP1127743A patent/JP2514249B2/ja not_active Expired - Fee Related
-
1990
- 1990-05-22 AU AU55802/90A patent/AU635740B2/en not_active Ceased
- 1990-05-22 DE DE9090305542T patent/DE69000640T2/de not_active Expired - Fee Related
- 1990-05-22 CA CA002017285A patent/CA2017285C/en not_active Expired - Lifetime
- 1990-05-22 DK DK90305542.4T patent/DK0399781T3/da active
- 1990-05-22 EP EP90305542A patent/EP0399781B1/en not_active Expired - Lifetime
- 1990-05-22 AT AT90305542T patent/ATE83667T1/de not_active IP Right Cessation
- 1990-05-22 ES ES90305542T patent/ES2053109T3/es not_active Expired - Lifetime
- 1990-05-23 KR KR1019900007438A patent/KR950004697B1/ko not_active IP Right Cessation
- 1990-05-23 US US07/527,461 patent/US5211950A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE83667T1 (de) | 1993-01-15 |
EP0399781A1 (en) | 1990-11-28 |
DE69000640T2 (de) | 1993-04-22 |
AU635740B2 (en) | 1993-04-01 |
CA2017285A1 (en) | 1990-11-23 |
DE69000640D1 (de) | 1993-02-04 |
JPH02306921A (ja) | 1990-12-20 |
EP0399781B1 (en) | 1992-12-23 |
ES2053109T3 (es) | 1994-07-16 |
CA2017285C (en) | 1996-12-10 |
KR950004697B1 (ko) | 1995-05-04 |
AU5580290A (en) | 1990-11-29 |
US5211950A (en) | 1993-05-18 |
DK0399781T3 (da) | 1993-02-01 |
JP2514249B2 (ja) | 1996-07-10 |
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Date | Code | Title | Description |
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A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E601 | Decision to refuse application | ||
J2X1 | Appeal (before the patent court) |
Free format text: APPEAL AGAINST DECISION TO DECLINE REFUSAL |
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G160 | Decision to publish patent application | ||
B701 | Decision to grant | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20080502 Year of fee payment: 14 |
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LAPS | Lapse due to unpaid annual fee |