DD219772A5 - Verfahren zur herstellung von spiro-hydantoin-derivaten - Google Patents

Verfahren zur herstellung von spiro-hydantoin-derivaten Download PDF

Info

Publication number
DD219772A5
DD219772A5 DD84262257A DD26225784A DD219772A5 DD 219772 A5 DD219772 A5 DD 219772A5 DD 84262257 A DD84262257 A DD 84262257A DD 26225784 A DD26225784 A DD 26225784A DD 219772 A5 DD219772 A5 DD 219772A5
Authority
DD
German Democratic Republic
Prior art keywords
spiro
fluoro
item
chroman
imidazolidine
Prior art date
Application number
DD84262257A
Other languages
German (de)
English (en)
Inventor
Reinhard Sarges
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DD219772A5 publication Critical patent/DD219772A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DD84262257A 1983-04-27 1984-04-24 Verfahren zur herstellung von spiro-hydantoin-derivaten DD219772A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/488,947 US4474967A (en) 1983-04-27 1983-04-27 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione

Publications (1)

Publication Number Publication Date
DD219772A5 true DD219772A5 (de) 1985-03-13

Family

ID=23941785

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84262257A DD219772A5 (de) 1983-04-27 1984-04-24 Verfahren zur herstellung von spiro-hydantoin-derivaten

Country Status (22)

Country Link
US (1) US4474967A (pt)
EP (1) EP0124327A3 (pt)
JP (1) JPS59205384A (pt)
KR (1) KR860000915B1 (pt)
AU (1) AU542142B2 (pt)
CA (1) CA1226866A (pt)
CS (1) CS250661B2 (pt)
DD (1) DD219772A5 (pt)
DK (1) DK208284A (pt)
ES (1) ES8607312A1 (pt)
FI (1) FI841657A (pt)
GR (1) GR81491B (pt)
HU (1) HU191755B (pt)
IL (1) IL71656A (pt)
NO (1) NO841627L (pt)
NZ (1) NZ207959A (pt)
PH (1) PH22869A (pt)
PL (1) PL142759B1 (pt)
PT (1) PT78476B (pt)
SU (1) SU1240362A3 (pt)
YU (1) YU43358B (pt)
ZA (1) ZA843091B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE37371T1 (de) * 1984-08-20 1988-10-15 Pfizer Verfahren zur herstellung asymmetrischer hydantoine.
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
US5059693A (en) * 1989-10-06 1991-10-22 Pfizer Inc. Process for making 3-aroyl-2-oxindole-1-carboxamides
GB9317764D0 (en) * 1993-08-26 1993-10-13 Pfizer Ltd Therapeutic compound
WO1999038497A2 (en) * 1998-01-30 1999-08-05 R-Tech Ueno, Ltd. Ophthalmic composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
CA1088945A (en) * 1976-10-18 1980-11-04 Pfizer Limited Hydantoin derivatives as therapeutic agents
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation

Also Published As

Publication number Publication date
SU1240362A3 (ru) 1986-06-23
ES531873A0 (es) 1986-06-01
PT78476B (en) 1986-08-28
YU43358B (en) 1989-06-30
DK208284D0 (da) 1984-04-26
ZA843091B (en) 1985-12-24
IL71656A (en) 1987-10-20
ES8607312A1 (es) 1986-06-01
KR840008355A (ko) 1984-12-14
PL247379A1 (en) 1985-03-26
IL71656A0 (en) 1984-07-31
KR860000915B1 (ko) 1986-07-18
GR81491B (pt) 1984-12-11
FI841657A0 (fi) 1984-04-26
EP0124327A2 (en) 1984-11-07
CA1226866A (en) 1987-09-15
DK208284A (da) 1984-10-28
CS250661B2 (en) 1987-05-14
AU2726384A (en) 1984-11-01
US4474967A (en) 1984-10-02
EP0124327A3 (en) 1985-07-31
FI841657A (fi) 1984-10-28
HU191755B (en) 1987-04-28
HUT34197A (en) 1985-02-28
AU542142B2 (en) 1985-02-07
PH22869A (en) 1989-01-19
NO841627L (no) 1984-10-29
YU74184A (en) 1986-10-31
PL142759B1 (en) 1987-11-30
JPS59205384A (ja) 1984-11-20
PT78476A (en) 1984-05-01
NZ207959A (en) 1987-04-30

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