DE68905171T2 - Benzol-derivate, ihre herstellung und pharmazeutische zusammensetzungen, die diese enthalten. - Google Patents

Benzol-derivate, ihre herstellung und pharmazeutische zusammensetzungen, die diese enthalten.

Info

Publication number
DE68905171T2
DE68905171T2 DE8989403670T DE68905171T DE68905171T2 DE 68905171 T2 DE68905171 T2 DE 68905171T2 DE 8989403670 T DE8989403670 T DE 8989403670T DE 68905171 T DE68905171 T DE 68905171T DE 68905171 T2 DE68905171 T2 DE 68905171T2
Authority
DE
Germany
Prior art keywords
contain
production
pharmaceutical compositions
benzene derivatives
benzene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989403670T
Other languages
English (en)
Other versions
DE68905171D1 (de
Inventor
Jean-Claude Breliere
Pierre Casellas
Serge Lavastre
Raymond Paul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Elf Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elf Sanofi SA filed Critical Elf Sanofi SA
Application granted granted Critical
Publication of DE68905171D1 publication Critical patent/DE68905171D1/de
Publication of DE68905171T2 publication Critical patent/DE68905171T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C225/18—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings the carbon skeleton containing also rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/35—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/38—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8989403670T 1988-12-30 1989-12-28 Benzol-derivate, ihre herstellung und pharmazeutische zusammensetzungen, die diese enthalten. Expired - Lifetime DE68905171T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8817538A FR2641276B1 (fr) 1988-12-30 1988-12-30 Derives du benzene, leur preparation et les compositions pharmaceutiques en contenant

Publications (2)

Publication Number Publication Date
DE68905171D1 DE68905171D1 (de) 1993-04-08
DE68905171T2 true DE68905171T2 (de) 1993-06-17

Family

ID=9373667

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989403670T Expired - Lifetime DE68905171T2 (de) 1988-12-30 1989-12-28 Benzol-derivate, ihre herstellung und pharmazeutische zusammensetzungen, die diese enthalten.

Country Status (22)

Country Link
US (2) US5354781A (de)
EP (1) EP0376850B1 (de)
JP (1) JP2588977B2 (de)
KR (1) KR0178366B1 (de)
AR (1) AR247548A1 (de)
AU (1) AU618439B2 (de)
CA (1) CA2006896C (de)
CZ (1) CZ419291A3 (de)
DE (1) DE68905171T2 (de)
DK (1) DK174505B1 (de)
ES (1) ES2055138T3 (de)
FI (1) FI98811C (de)
FR (1) FR2641276B1 (de)
GR (1) GR3007357T3 (de)
HK (1) HK1000541A1 (de)
HU (1) HU211155A9 (de)
IE (1) IE63689B1 (de)
IL (1) IL92889A (de)
NO (1) NO171847C (de)
NZ (1) NZ232010A (de)
PT (1) PT92761B (de)
ZA (1) ZA899955B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658821B1 (fr) * 1990-02-28 1994-09-16 Jouveinal Sa Nouvelles propanamines, leurs proprietes pharmacologiques et leur application a des fins therapeutiques, notamment antidiarrheuiques.
FR2742051B1 (fr) * 1995-12-06 1998-02-06 Synthelabo Utilisation de composes ayant une affinite pour le site de liaison du (3h)ifenprodil pour la fabrication de medicaments utiles dans la prevention et le traitement des neuropathies
FR2751645B1 (fr) * 1996-07-29 1998-12-24 Sanofi Sa Amines pour la fabrication de medicaments destines a empecher la proliferation de cellules tumorales
FR2794742B1 (fr) * 1999-06-11 2005-06-03 Sanofi Synthelabo Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant
FR2887454B1 (fr) * 2005-06-28 2009-06-05 Sanofi Aventis Sa Combinaisons antitumorales contenant des derives du taxane et des sigma ligands
DE102006031813B4 (de) 2006-07-07 2011-04-28 Christian-Albrechts-Universität Zu Kiel Verwendung basischer Acetophenone als Hemmstoffe von NO-Synthasen
CA3031818A1 (en) * 2016-07-27 2018-02-01 Case Western Reserve University Compounds and methods of promoting myelination
US10918610B2 (en) * 2017-12-22 2021-02-16 Case Western Reserve University Compounds and methods of promoting myelination
WO2020117654A1 (en) 2018-12-03 2020-06-11 Convelo Therapeutics, Inc. Crystalline forms of multicyclic compounds and uses thereof
WO2022058533A1 (en) 2020-09-17 2022-03-24 Meletios Therapeutics Compounds for treating virus infections

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1468761A (fr) * 1965-08-05 1967-02-10 Amines et esters carbamiques acétyléniques
AT316516B (de) * 1970-12-09 1974-07-10 Sumitomo Chemical Co Verfahren zur Herstellung von neuen Aminoalkoholen und von deren Säureadditionssalzen
GB1430063A (en) * 1972-03-24 1976-03-31 Wallis Separators Separator
GB1475314A (en) * 1973-11-02 1977-06-01 Cm Ind Phenyl-propylamine derivatives
US4104383A (en) * 1973-11-02 1978-08-01 C M Industries Derivatives of phenylpropenylamine
IT1113391B (it) * 1979-05-09 1986-01-20 Maggioni Farma Derivati fenilcicloesanici ad attivita' antidepressiva
DE3019497A1 (de) * 1980-05-22 1981-11-26 Bayer Ag, 5090 Leverkusen Aminopropiophenon-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
DE3541181A1 (de) * 1985-11-21 1987-05-27 Basf Ag Propylamine, verfahren zu ihrer herstellung und ihre verwendung als fungizide

Also Published As

Publication number Publication date
EP0376850A1 (de) 1990-07-04
NO171847C (no) 1993-05-12
PT92761A (pt) 1990-06-29
JPH032116A (ja) 1991-01-08
KR0178366B1 (ko) 1999-05-15
FR2641276A1 (fr) 1990-07-06
NO171847B (no) 1993-02-01
US5354781A (en) 1994-10-11
NZ232010A (en) 1992-03-26
HU211155A9 (en) 1995-10-30
KR900009580A (ko) 1990-07-04
CA2006896A1 (en) 1990-06-30
CZ419291A3 (en) 1993-05-12
NO895220D0 (no) 1989-12-22
AU4737989A (en) 1990-07-05
FR2641276B1 (fr) 1991-07-12
AR247548A1 (es) 1995-01-31
US5449693A (en) 1995-09-12
FI98811C (fi) 1997-08-25
DK674589A (da) 1990-07-01
NO895220L (no) 1990-07-02
AU618439B2 (en) 1991-12-19
CA2006896C (en) 1998-06-02
IE63689B1 (en) 1995-05-31
FI98811B (fi) 1997-05-15
IL92889A (en) 1994-02-27
DE68905171D1 (de) 1993-04-08
DK674589D0 (da) 1989-12-29
ES2055138T3 (es) 1994-08-16
IE894209L (en) 1990-06-30
EP0376850B1 (de) 1993-03-03
JP2588977B2 (ja) 1997-03-12
IL92889A0 (en) 1990-09-17
HK1000541A1 (en) 1998-04-03
GR3007357T3 (de) 1993-07-30
FI896342A0 (fi) 1989-12-29
DK174505B1 (da) 2003-04-28
ZA899955B (en) 1990-09-26
PT92761B (pt) 1996-01-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI, PARIS, FR

8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-SYNTHELABO, PARIS, FR

8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS, PARIS, FR