DD209971A5 - Verfahren zur herstellung eines pharmazeutischen praeparates - Google Patents

Verfahren zur herstellung eines pharmazeutischen praeparates Download PDF

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Publication number
DD209971A5
DD209971A5 DD83252303A DD25230383A DD209971A5 DD 209971 A5 DD209971 A5 DD 209971A5 DD 83252303 A DD83252303 A DD 83252303A DD 25230383 A DD25230383 A DD 25230383A DD 209971 A5 DD209971 A5 DD 209971A5
Authority
DD
German Democratic Republic
Prior art keywords
release
carbohydrate
mixture
microcapsules
drug
Prior art date
Application number
DD83252303A
Other languages
German (de)
English (en)
Inventor
Anders G V Kaellstrand
Kjell J Mattsson
Rolf I Sjoeqvist
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of DD209971A5 publication Critical patent/DD209971A5/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DD83252303A 1982-06-24 1983-06-23 Verfahren zur herstellung eines pharmazeutischen praeparates DD209971A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8203953A SE8203953D0 (sv) 1982-06-24 1982-06-24 Pharmaceutical mixture

Publications (1)

Publication Number Publication Date
DD209971A5 true DD209971A5 (de) 1984-05-30

Family

ID=20347191

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83252303A DD209971A5 (de) 1982-06-24 1983-06-23 Verfahren zur herstellung eines pharmazeutischen praeparates

Country Status (29)

Country Link
EP (1) EP0101418B1 (fr)
JP (1) JPS5916822A (fr)
KR (1) KR910000028B1 (fr)
AR (1) AR231075A1 (fr)
AT (1) ATE59286T1 (fr)
AU (1) AU561954B2 (fr)
BG (1) BG51341A3 (fr)
CA (1) CA1214726A (fr)
CS (1) CS257769B2 (fr)
CY (1) CY1468A (fr)
DD (1) DD209971A5 (fr)
DE (1) DE3382086D1 (fr)
DK (1) DK161365C (fr)
ES (1) ES523536A0 (fr)
FI (1) FI85213C (fr)
GB (1) GB2122490B (fr)
GR (1) GR78604B (fr)
HK (1) HK98786A (fr)
HU (1) HU189300B (fr)
IE (1) IE55204B1 (fr)
IS (1) IS1325B6 (fr)
MY (1) MY8700292A (fr)
NO (1) NO168745C (fr)
NZ (1) NZ204639A (fr)
PH (1) PH21911A (fr)
PT (1) PT76919B (fr)
SE (1) SE8203953D0 (fr)
SU (1) SU1722207A3 (fr)
ZA (1) ZA833931B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0729927B2 (ja) * 1983-04-09 1995-04-05 日研化学株式会社 テオフィリン徐放性製剤
SE8405611D0 (sv) * 1984-11-09 1984-11-09 Astra Laekemedel Ab Process for stabilization of bacampicillin hydrochloride
IT1183575B (it) * 1985-05-08 1987-10-22 Eurand Spa Formulazione deodorando ad effetto modulante sulla trfaspirazione
NL8503539A (nl) * 1986-01-02 1987-07-16 Warner Lambert Co Sucrose-vrije preparaten.
US4780320A (en) * 1986-04-29 1988-10-25 Pharmetrix Corp. Controlled release drug delivery system for the periodontal pocket
SE8605515D0 (sv) * 1986-12-22 1986-12-22 Astra Laekemedel Ab A liquid dosage form for oral administration of a pharmaceutically active substance
US4874613A (en) * 1987-03-06 1989-10-17 Baker Cummins Pharmaceuticals, Inc. Taste concealing pharmaceutical dosage unit
US5427935A (en) * 1987-07-24 1995-06-27 The Regents Of The University Of Michigan Hybrid membrane bead and process for encapsulating materials in semi-permeable hybrid membranes
SE463542B (sv) * 1987-08-31 1990-12-10 Lejus Medical Ab Granulaer instanticerbar produkt samt foerfarande foer dess framstaellning
JPH03504968A (ja) * 1988-04-19 1991-10-31 サウスウェスト・リサーチ・インスティチュート 塩感受性シェル物質を有するカプセルからの活性成分の制御放出
US5064650A (en) * 1988-04-19 1991-11-12 Southwest Research Institute Controlled-release salt sensitive capsule for oral use and adhesive system
FR2653337B1 (fr) * 1989-10-23 1992-02-07 Dow Corning Sa Element a liberation prolongee et procede pour le fabriquer.
CA2068402C (fr) * 1991-06-14 1998-09-22 Michael R. Hoy Enrobage pour masquer le gout pouvant etre utilise dans des comprimes pharmaceutiques croquables
US5364634A (en) * 1991-11-08 1994-11-15 Southwest Research Institute Controlled-release PH sensitive capsule and adhesive system and method
DE4200821A1 (de) * 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
JP3265680B2 (ja) * 1992-03-12 2002-03-11 大正製薬株式会社 経口製剤用組成物
DE4312656C2 (de) * 1993-04-19 1996-01-25 Beiersdorf Ag Kühlend wirkende kosmetische oder dermatologische Zusammensetzungen
DE4423078B4 (de) * 1994-07-01 2005-01-13 Awd.Pharma Gmbh & Co. Kg Verfahren zur Herstellung einer Carbamazepin-Arzneiform mit verzögerter Wirkstofffreisetzung
JP3470198B2 (ja) * 1995-05-02 2003-11-25 大正製薬株式会社 経口投与用組成物
DE19706978A1 (de) * 1997-02-21 1998-08-27 Ulrich Dr Posanski Kombinationspräparat für oral applizierbare Antibiotika
US7943585B2 (en) 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297088A (fr) * 1961-01-31
US3689654A (en) * 1970-09-14 1972-09-05 Morton Norwich Products Inc Pharmaceutical compositions
ES434971A1 (es) * 1974-02-22 1977-05-16 Wellcome Found Metodo para producir un preparado farmaceutico que comprendeuna solucin de digoxina en una envolvente de capsula solu- ble.
SE8003805L (sv) * 1980-05-21 1981-11-22 Haessle Ab En farmaceutisk beredning med forbettrade utlosningsegenskap
US4321253A (en) * 1980-08-22 1982-03-23 Beatty Morgan L Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration
SE8103843L (sv) * 1981-06-18 1982-12-19 Astra Laekemedel Ab Farmaceutisk mixtur
JPS57209223A (en) * 1981-06-19 1982-12-22 Tanabe Seiyaku Co Ltd Microcapsule for intracranial anti hypotension and its production

Also Published As

Publication number Publication date
ATE59286T1 (de) 1991-01-15
FI832197A0 (fi) 1983-06-16
CY1468A (en) 1989-07-21
ZA833931B (en) 1984-07-25
GR78604B (fr) 1984-09-27
FI85213B (fi) 1991-12-13
AR231075A1 (es) 1984-09-28
DK161365C (da) 1991-12-09
JPS5916822A (ja) 1984-01-28
GB2122490A (en) 1984-01-18
ES8403720A1 (es) 1984-04-01
JPH0559089B2 (fr) 1993-08-30
BG51341A3 (en) 1993-04-15
CA1214726A (fr) 1986-12-02
SE8203953D0 (sv) 1982-06-24
HU189300B (en) 1986-06-30
EP0101418A3 (en) 1984-11-14
AU561954B2 (en) 1987-05-21
AU1594383A (en) 1984-01-05
HK98786A (en) 1986-12-24
EP0101418B1 (fr) 1990-12-27
NZ204639A (en) 1986-01-24
NO832293L (no) 1983-12-27
DK272383A (da) 1983-12-25
NO168745B (no) 1991-12-23
IE55204B1 (en) 1990-07-04
MY8700292A (en) 1987-12-31
PT76919B (en) 1986-04-09
DE3382086D1 (de) 1991-02-07
IE831462L (en) 1983-12-24
FI832197L (fi) 1983-12-25
PH21911A (en) 1988-04-08
SU1722207A3 (ru) 1992-03-23
IS2824A7 (is) 1983-12-25
PT76919A (en) 1983-07-01
NO168745C (no) 1992-04-01
IS1325B6 (is) 1988-08-03
GB2122490B (en) 1986-04-03
FI85213C (fi) 1992-03-25
ES523536A0 (es) 1984-04-01
KR840005024A (ko) 1984-11-03
EP0101418A2 (fr) 1984-02-22
KR910000028B1 (ko) 1991-01-19
GB8317071D0 (en) 1983-07-27
DK161365B (da) 1991-07-01
CS463683A2 (en) 1987-11-12
CS257769B2 (en) 1988-06-15
DK272383D0 (da) 1983-06-14

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