DD209834A5 - Verfahren zur herstellung von n-(2-methoxyethyl)-noroxymorphon - Google Patents

Verfahren zur herstellung von n-(2-methoxyethyl)-noroxymorphon Download PDF

Info

Publication number
DD209834A5
DD209834A5 DD83251639A DD25163983A DD209834A5 DD 209834 A5 DD209834 A5 DD 209834A5 DD 83251639 A DD83251639 A DD 83251639A DD 25163983 A DD25163983 A DD 25163983A DD 209834 A5 DD209834 A5 DD 209834A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
noroxymorphone
methoxyethyl
acid
compound
Prior art date
Application number
DD83251639A
Other languages
German (de)
English (en)
Inventor
Herbert Merz
Adolf Langbein
Klaus Stockhaus
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of DD209834A5 publication Critical patent/DD209834A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DD83251639A 1982-06-03 1983-06-01 Verfahren zur herstellung von n-(2-methoxyethyl)-noroxymorphon DD209834A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823220831 DE3220831A1 (de) 1982-06-03 1982-06-03 N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
DD209834A5 true DD209834A5 (de) 1984-05-23

Family

ID=6165151

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83251639A DD209834A5 (de) 1982-06-03 1983-06-01 Verfahren zur herstellung von n-(2-methoxyethyl)-noroxymorphon

Country Status (27)

Country Link
US (1) US4473573A (ko)
EP (1) EP0096279B1 (ko)
JP (1) JPS591487A (ko)
KR (1) KR900006754B1 (ko)
AU (1) AU558319B2 (ko)
CA (1) CA1196633A (ko)
CS (1) CS236882B2 (ko)
CZ (1) CZ410691A3 (ko)
DD (1) DD209834A5 (ko)
DE (2) DE3220831A1 (ko)
DK (1) DK156068C (ko)
ES (1) ES522897A0 (ko)
FI (1) FI78101C (ko)
GB (1) GB2121041B (ko)
GR (1) GR78273B (ko)
HK (1) HK1389A (ko)
HU (1) HU185832B (ko)
IE (1) IE55232B1 (ko)
IL (1) IL68872A0 (ko)
NO (1) NO158579C (ko)
NZ (1) NZ204451A (ko)
PH (1) PH19518A (ko)
PL (1) PL139569B1 (ko)
PT (1) PT76805B (ko)
SG (1) SG58788G (ko)
SU (1) SU1195909A3 (ko)
ZA (1) ZA833981B (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132159A1 (de) * 1991-09-27 1993-04-01 Boehringer Ingelheim Kg 14-hydroxy-n-(2-methoxyethyl)-7,8-dihydromorphin und -norisomorphin, verfahren zu deren herstellung und deren verwendung als arzneimittel
NZ600379A (en) 2009-12-04 2014-05-30 Alkermes Pharma Ireland Ltd Morphinan derivatives for the treatment of drug overdose
SI2608670T1 (sl) 2010-08-23 2019-04-30 Alkermes Pharma Ireland Limited Postopki za zdravljenje pridobivanja teže, ki je posledica uporabe antipsihotičnih zdravil
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
EP3003311A2 (en) 2013-05-24 2016-04-13 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
AU2014268361B2 (en) 2013-05-24 2018-09-06 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332950A (en) * 1963-03-23 1967-07-25 Endo Lab 14-hydroxydihydronormorphinone derivatives
DE2538075A1 (de) * 1975-08-27 1977-03-17 Boehringer Sohn Ingelheim N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
AU1531483A (en) 1983-12-08
PH19518A (en) 1986-05-14
CS236882B2 (en) 1985-05-15
GR78273B (ko) 1984-09-26
NZ204451A (en) 1986-07-11
PT76805B (de) 1986-04-09
KR840005146A (ko) 1984-11-03
SG58788G (en) 1989-03-10
PL242312A1 (en) 1985-04-09
IE831299L (en) 1983-12-03
PL139569B1 (en) 1987-02-28
KR900006754B1 (ko) 1990-09-20
NO158579B (no) 1988-06-27
JPH0373552B2 (ko) 1991-11-22
GB2121041B (en) 1985-09-11
DK250783D0 (da) 1983-06-02
FI831941L (fi) 1983-12-04
GB8315292D0 (en) 1983-07-06
EP0096279A1 (de) 1983-12-21
DK250783A (da) 1983-12-04
FI78101C (fi) 1989-06-12
ES8403487A1 (es) 1984-03-16
EP0096279B1 (de) 1985-11-06
DE3220831A1 (de) 1983-12-08
ZA833981B (en) 1985-01-30
DK156068B (da) 1989-06-19
HK1389A (en) 1989-01-13
DE3361165D1 (en) 1985-12-12
NO158579C (no) 1988-10-05
DK156068C (da) 1989-11-06
JPS591487A (ja) 1984-01-06
ES522897A0 (es) 1984-03-16
IE55232B1 (en) 1990-07-04
IL68872A0 (en) 1983-10-31
CA1196633A (en) 1985-11-12
GB2121041A (en) 1983-12-14
FI78101B (fi) 1989-02-28
HU185832B (en) 1985-04-28
SU1195909A3 (ru) 1985-11-30
US4473573A (en) 1984-09-25
PT76805A (de) 1983-07-01
FI831941A0 (fi) 1983-05-31
CZ410691A3 (en) 1993-02-17
AU558319B2 (en) 1987-01-29
NO831995L (no) 1983-12-05

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Legal Events

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ENJ Ceased due to non-payment of renewal fee