FI831941L - Foerfarande foer framstaellning av n-(2-metoxi-etyl)-noroximorfon och dess syraadditionssalter - Google Patents

Foerfarande foer framstaellning av n-(2-metoxi-etyl)-noroximorfon och dess syraadditionssalter

Info

Publication number
FI831941L
FI831941L FI831941A FI831941A FI831941L FI 831941 L FI831941 L FI 831941L FI 831941 A FI831941 A FI 831941A FI 831941 A FI831941 A FI 831941A FI 831941 L FI831941 L FI 831941L
Authority
FI
Finland
Prior art keywords
noroximorphone
syringes
methoxy
ethyl
frequency refrigeration
Prior art date
Application number
FI831941A
Other languages
English (en)
Other versions
FI78101B (fi
FI831941A0 (fi
FI78101C (fi
Inventor
Herbert Merz
Adolf Langbein
Klaus Stockhaus
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of FI831941A0 publication Critical patent/FI831941A0/fi
Publication of FI831941L publication Critical patent/FI831941L/fi
Publication of FI78101B publication Critical patent/FI78101B/fi
Application granted granted Critical
Publication of FI78101C publication Critical patent/FI78101C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI831941A 1982-06-03 1983-05-31 Foerfarande foer framstaellning av farmakologiskt vaerdefulla n-(2-metoxietyl)-noroximorfoner. FI78101C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3220831 1982-06-03
DE19823220831 DE3220831A1 (de) 1982-06-03 1982-06-03 N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung

Publications (4)

Publication Number Publication Date
FI831941A0 FI831941A0 (fi) 1983-05-31
FI831941L true FI831941L (fi) 1983-12-04
FI78101B FI78101B (fi) 1989-02-28
FI78101C FI78101C (fi) 1989-06-12

Family

ID=6165151

Family Applications (1)

Application Number Title Priority Date Filing Date
FI831941A FI78101C (fi) 1982-06-03 1983-05-31 Foerfarande foer framstaellning av farmakologiskt vaerdefulla n-(2-metoxietyl)-noroximorfoner.

Country Status (27)

Country Link
US (1) US4473573A (fi)
EP (1) EP0096279B1 (fi)
JP (1) JPS591487A (fi)
KR (1) KR900006754B1 (fi)
AU (1) AU558319B2 (fi)
CA (1) CA1196633A (fi)
CS (1) CS236882B2 (fi)
CZ (1) CZ410691A3 (fi)
DD (1) DD209834A5 (fi)
DE (2) DE3220831A1 (fi)
DK (1) DK156068C (fi)
ES (1) ES8403487A1 (fi)
FI (1) FI78101C (fi)
GB (1) GB2121041B (fi)
GR (1) GR78273B (fi)
HK (1) HK1389A (fi)
HU (1) HU185832B (fi)
IE (1) IE55232B1 (fi)
IL (1) IL68872A0 (fi)
NO (1) NO158579C (fi)
NZ (1) NZ204451A (fi)
PH (1) PH19518A (fi)
PL (1) PL139569B1 (fi)
PT (1) PT76805B (fi)
SG (1) SG58788G (fi)
SU (1) SU1195909A3 (fi)
ZA (1) ZA833981B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132159A1 (de) * 1991-09-27 1993-04-01 Boehringer Ingelheim Kg 14-hydroxy-n-(2-methoxyethyl)-7,8-dihydromorphin und -norisomorphin, verfahren zu deren herstellung und deren verwendung als arzneimittel
JP5691042B2 (ja) 2009-12-04 2015-04-01 アルカーメス ファーマ アイルランド リミテッド 薬物過量摂取の治療のためのモルヒナン誘導体
US8778960B2 (en) 2010-08-23 2014-07-15 Alkermes Pharma Ireland Limited Methods for treating antipsychotic-induced weight gain
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
US9656961B2 (en) 2013-05-24 2017-05-23 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
NZ631018A (en) 2013-05-24 2017-12-22 Alkermes Pharma Ireland Ltd Morphan and morphinan analogues, and methods of use
WO2022101444A1 (en) 2020-11-12 2022-05-19 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332950A (en) * 1963-03-23 1967-07-25 Endo Lab 14-hydroxydihydronormorphinone derivatives
DE2538075A1 (de) * 1975-08-27 1977-03-17 Boehringer Sohn Ingelheim N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DD209834A5 (de) 1984-05-23
GR78273B (fi) 1984-09-26
SU1195909A3 (ru) 1985-11-30
IE831299L (en) 1983-12-03
FI78101B (fi) 1989-02-28
DK250783D0 (da) 1983-06-02
GB2121041A (en) 1983-12-14
DE3220831A1 (de) 1983-12-08
ZA833981B (en) 1985-01-30
PT76805A (de) 1983-07-01
FI831941A0 (fi) 1983-05-31
PH19518A (en) 1986-05-14
CA1196633A (en) 1985-11-12
DK250783A (da) 1983-12-04
PT76805B (de) 1986-04-09
SG58788G (en) 1989-03-10
GB8315292D0 (en) 1983-07-06
IL68872A0 (en) 1983-10-31
AU558319B2 (en) 1987-01-29
JPS591487A (ja) 1984-01-06
KR840005146A (ko) 1984-11-03
NZ204451A (en) 1986-07-11
IE55232B1 (en) 1990-07-04
HK1389A (en) 1989-01-13
FI78101C (fi) 1989-06-12
DK156068B (da) 1989-06-19
NO158579B (no) 1988-06-27
PL139569B1 (en) 1987-02-28
KR900006754B1 (ko) 1990-09-20
CS236882B2 (en) 1985-05-15
CZ410691A3 (en) 1993-02-17
GB2121041B (en) 1985-09-11
EP0096279A1 (de) 1983-12-21
ES522897A0 (es) 1984-03-16
JPH0373552B2 (fi) 1991-11-22
PL242312A1 (en) 1985-04-09
DK156068C (da) 1989-11-06
HU185832B (en) 1985-04-28
NO831995L (no) 1983-12-05
EP0096279B1 (de) 1985-11-06
DE3361165D1 (en) 1985-12-12
US4473573A (en) 1984-09-25
NO158579C (no) 1988-10-05
AU1531483A (en) 1983-12-08
ES8403487A1 (es) 1984-03-16

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BOEHRINGER INGELHEIM KG