DD205906A5 - Verfahren zur herstellung von n-(vinblastinoyl-23)-derivaten von aminosaeuren - Google Patents

Verfahren zur herstellung von n-(vinblastinoyl-23)-derivaten von aminosaeuren Download PDF

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Publication number
DD205906A5
DD205906A5 DD82245703A DD24570382A DD205906A5 DD 205906 A5 DD205906 A5 DD 205906A5 DD 82245703 A DD82245703 A DD 82245703A DD 24570382 A DD24570382 A DD 24570382A DD 205906 A5 DD205906 A5 DD 205906A5
Authority
DD
German Democratic Republic
Prior art keywords
group
vinblastine
ester
hydrogen atom
reaction
Prior art date
Application number
DD82245703A
Other languages
German (de)
English (en)
Inventor
Andre B L Trouet
Jean A A J Hannart
Kandukuri S B Rao
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem Sa filed Critical Omnichem Sa
Publication of DD205906A5 publication Critical patent/DD205906A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DD82245703A 1981-12-08 1982-12-08 Verfahren zur herstellung von n-(vinblastinoyl-23)-derivaten von aminosaeuren DD205906A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU83822A LU83822A1 (fr) 1981-12-08 1981-12-08 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique

Publications (1)

Publication Number Publication Date
DD205906A5 true DD205906A5 (de) 1984-01-11

Family

ID=19729780

Family Applications (1)

Application Number Title Priority Date Filing Date
DD82245703A DD205906A5 (de) 1981-12-08 1982-12-08 Verfahren zur herstellung von n-(vinblastinoyl-23)-derivaten von aminosaeuren

Country Status (24)

Country Link
JP (1) JPS58116491A (hu)
AT (1) AT390958B (hu)
AU (1) AU564951B2 (hu)
BE (1) BE895262A (hu)
CA (1) CA1198422A (hu)
CH (1) CH655727A5 (hu)
DD (1) DD205906A5 (hu)
DE (1) DE3245269A1 (hu)
DK (1) DK161833C (hu)
ES (1) ES8401768A1 (hu)
FR (1) FR2517680B1 (hu)
GB (1) GB2111055B (hu)
GR (1) GR77280B (hu)
HU (1) HU187803B (hu)
IE (1) IE55283B1 (hu)
IL (1) IL67366A (hu)
IT (1) IT1157126B (hu)
LU (1) LU83822A1 (hu)
NL (1) NL8204711A (hu)
NZ (1) NZ202708A (hu)
OA (1) OA07270A (hu)
PT (1) PT75949B (hu)
SE (1) SE452622B (hu)
ZA (1) ZA828823B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0124502B1 (fr) * 1983-04-29 1991-06-12 OMNICHEM Société anonyme Nouveaux conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques contenant ces conjugués
US4667030A (en) * 1985-06-17 1987-05-19 Eli Lilly And Company Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
EP0233101A1 (fr) * 1986-01-13 1987-08-19 Ire-Celltarg S.A. Dérivés de vinblastine et composition pharmaceutique les contenant
US4906086A (en) * 1987-06-19 1990-03-06 Honda Giken Kogyo Kabushiki Kaisha Rearview mirror device for motorcycles
FR2626882B1 (fr) * 1988-02-08 1991-11-08 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
CN105121447B (zh) * 2013-04-19 2018-02-02 暨南大学 长春碱类衍生物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US3848234A (en) * 1973-04-04 1974-11-12 Sperry Rand Corp Multi-processor system with multiple cache memories
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.

Also Published As

Publication number Publication date
FR2517680A1 (fr) 1983-06-10
CH655727A5 (fr) 1986-05-15
ZA828823B (en) 1983-09-28
GB2111055A (en) 1983-06-29
NZ202708A (en) 1986-01-24
NL8204711A (nl) 1983-07-01
IT8268431A0 (it) 1982-12-07
LU83822A1 (fr) 1983-09-01
ES517942A0 (es) 1984-01-01
IL67366A0 (en) 1983-03-31
ES8401768A1 (es) 1984-01-01
BE895262A (fr) 1983-06-07
PT75949B (fr) 1985-10-04
AU564951B2 (en) 1987-09-03
JPH0449557B2 (hu) 1992-08-11
DK161833B (da) 1991-08-19
GB2111055B (en) 1985-07-10
AT390958B (de) 1990-07-25
JPS58116491A (ja) 1983-07-11
PT75949A (fr) 1983-01-01
DK161833C (da) 1992-01-20
SE8206981L (sv) 1983-06-09
HU187803B (en) 1986-02-28
AU9084782A (en) 1983-06-16
ATA444982A (de) 1990-01-15
SE8206981D0 (sv) 1982-12-07
OA07270A (fr) 1984-04-30
DK541882A (da) 1983-06-09
CA1198422A (en) 1985-12-24
IL67366A (en) 1987-01-30
IE55283B1 (en) 1990-08-01
SE452622B (sv) 1987-12-07
FR2517680B1 (fr) 1990-05-25
DE3245269A1 (de) 1983-07-21
GR77280B (hu) 1984-09-11
IT1157126B (it) 1987-02-11
IE822906L (en) 1983-06-08

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