DD202561A5 - Verfahren zur Herstellung von Salzen von Naphthyridin- und Chinolin-verbindungen - Google Patents

Verfahren zur Herstellung von Salzen von Naphthyridin- und Chinolin-verbindungen Download PDF

Info

Publication number
DD202561A5
DD202561A5 DD24062982A DD24062982A DD202561A5 DD 202561 A5 DD202561 A5 DD 202561A5 DD 24062982 A DD24062982 A DD 24062982A DD 24062982 A DD24062982 A DD 24062982A DD 202561 A5 DD202561 A5 DD 202561A5
Authority
DD
German Democratic Republic
Prior art keywords
acid
compound
solution
salts
gluconate
Prior art date
Application number
DD24062982A
Other languages
German (de)
English (en)
Inventor
Thomas F Mich
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DD202561A5 publication Critical patent/DD202561A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
DD24062982A 1981-06-11 1982-06-10 Verfahren zur Herstellung von Salzen von Naphthyridin- und Chinolin-verbindungen DD202561A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27260181A 1981-06-11 1981-06-11
US33418281A 1981-12-24 1981-12-24

Publications (1)

Publication Number Publication Date
DD202561A5 true DD202561A5 (de) 1983-09-21

Family

ID=26955624

Family Applications (1)

Application Number Title Priority Date Filing Date
DD24062982A DD202561A5 (de) 1981-06-11 1982-06-10 Verfahren zur Herstellung von Salzen von Naphthyridin- und Chinolin-verbindungen

Country Status (17)

Country Link
EP (1) EP0067666B1 (ko)
KR (1) KR880002087B1 (ko)
AU (1) AU551596B2 (ko)
CA (1) CA1191842A (ko)
DD (1) DD202561A5 (ko)
DE (1) DE3267135D1 (ko)
DK (1) DK155998C (ko)
ES (1) ES512969A0 (ko)
FI (1) FI78292C (ko)
GR (1) GR77194B (ko)
HU (1) HU188181B (ko)
IE (1) IE53259B1 (ko)
IL (1) IL66027A (ko)
NO (1) NO157739C (ko)
NZ (1) NZ200908A (ko)
PH (1) PH19091A (ko)
SU (1) SU1192624A3 (ko)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3333719A1 (de) * 1983-09-17 1985-04-04 Bayer Ag Loesungen milchsaurer salze von piperazinylchinolon- und piperazinyl-azachinoloncarbonsaeuren
IT1196051B (it) * 1984-03-16 1988-11-10 Schiena Ricerche Composti ad attivita' antibatterica
DE3517709A1 (de) * 1985-01-05 1986-07-10 Bayer Ag Basische zubereitungen von chinoloncarbonsaeuren
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
HUT40429A (en) * 1985-04-29 1986-12-28 Chinoin Gyogyszer Es Vegyeszet Process for production of salts of derivatives of kynolin carbonic acid
DE3525335A1 (de) * 1985-07-16 1987-01-22 Bayer Ag Embonate von chinoloncarbonsaeuren und ihren derivaten
DE3537761A1 (de) * 1985-10-24 1987-04-30 Bayer Ag Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure
IT1196429B (it) * 1986-07-01 1988-11-16 Mediolanum Farmaceutici Srl Processo per la preparazione di pirido benzotiazine ad attivita' antibatterica e loro sali con acidi solfonici
IL80459A (en) * 1986-10-30 1991-04-15 Abic Ltd Water-soluble adduct of norfloxacin and nicotinic acid
US5188833A (en) * 1987-12-28 1993-02-23 Kyorin Seiyaku Kabushiki Kaisha Freeze-dried pharmaceutical preparations for parenteral use
JPH01175935A (ja) * 1987-12-28 1989-07-12 Kyorin Pharmaceut Co Ltd 凍結乾燥注射剤
US4948894A (en) * 1989-02-21 1990-08-14 American Cyanamid Company 8-fluoro and 7, 8, 10-trifluoro-9-(substituted)-6-oxo-6H-benzo-(C)quinolizine-5-carboxylic acids
KR0159540B1 (ko) * 1992-01-21 1998-12-01 김정순 퀴놀론-카복실산의 염 및 그 함유조성물
ES2127036B1 (es) * 1994-03-21 1999-11-16 Ind Quimica Agropecuaria S A Aducto de norfloxacina soluble en agua.
ES2088742B1 (es) * 1994-06-29 1997-03-16 Salvat Lab Sa Composicion antibiotica de aplicacion otica.
DE19500784A1 (de) * 1995-01-13 1996-07-18 Bayer Ag Enrofloxacin-Injektions- oder Infusionslösungen
MA24500A1 (fr) 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
DK2134712T3 (da) 2007-04-13 2013-11-18 Dong Wha Pharm Co Ltd Aspartat af 1-cyclopropyl-6-fluoro-7-(8-methoxyimino-2,6-diaza-spiro(3, 4)oct-6-yl)-4-oxo-1,4-dihydro-(1,8) naphthyridin-3-karboxylsyre, fremgangsmåde til fremstilling af samme og antimikrobielt farmaceutisk sammensætning omfattende samme

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR223983A1 (es) * 1978-08-25 1981-10-15 Dainippon Pharmaceutical Co Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico
ZA811304B (en) * 1980-03-11 1982-06-30 Warner Lambert Co Pharmaceutical salts of 4'-(9-acridinylamino)methanesulfon-m-anisidide

Also Published As

Publication number Publication date
PH19091A (en) 1985-12-19
KR880002087B1 (ko) 1988-10-15
NO157739C (no) 1988-05-11
IL66027A (en) 1986-02-28
FI822066A0 (fi) 1982-06-10
ES8304117A1 (es) 1983-02-16
NO157739B (no) 1988-02-01
NO821931L (no) 1982-12-13
KR840000544A (ko) 1984-02-25
CA1191842A (en) 1985-08-13
EP0067666B1 (en) 1985-10-30
EP0067666A1 (en) 1982-12-22
DK261582A (da) 1982-12-12
IE821390L (en) 1982-12-11
SU1192624A3 (ru) 1985-11-15
IL66027A0 (en) 1982-09-30
ES512969A0 (es) 1983-02-16
AU551596B2 (en) 1986-05-08
IE53259B1 (en) 1988-09-28
HU188181B (en) 1986-03-28
DE3267135D1 (en) 1985-12-05
GR77194B (ko) 1984-09-11
DK155998C (da) 1989-11-06
FI78292B (fi) 1989-03-31
AU8475782A (en) 1982-12-16
NZ200908A (en) 1984-09-28
FI78292C (fi) 1989-07-10
DK155998B (da) 1989-06-12

Similar Documents

Publication Publication Date Title
DD202561A5 (de) Verfahren zur Herstellung von Salzen von Naphthyridin- und Chinolin-verbindungen
DE60026144T2 (de) Benzamidformulierung mit histon-deacetylase-inhibitoraktivität
DE69005992T2 (de) Psychotropische Wirkstoffe enthaltende stabilisierte Lösungen.
DE69014141T2 (de) Verwendung von Benzimidazol-Derivaten als antibakterielle Mittel.
DE2332878C2 (de) Salze von Cephalosporinen mit Arginin und Lysin, ihre Herstellung und injizierbare pharmazeutische Zubereitungen
DE3031710A1 (de) Salze von (+)-catechin, deren herstellung und verwendung sowie diese salze enthaltende pharmazeutische zubereitungen.
DE60025627T2 (de) Pharmazeutische lösung von levosimendan
EP2865391B1 (de) Verfahren zur Herstellung einer gefriergetrockneten pharmazeutischen Zusammensetzung mit Gehalt an Mitomycin C
EP0806955B1 (de) Enrofloxacin-injektions- oder infusionslösungen
DE3686514T2 (de) N-(2-carboxy)-ethyl-1,8-naphthalenimid und dessen salze zur behandlung von diabetischen retinopathien und neuropathien.
DE3000743A1 (de) Arzneipraeparat auf der basis eines salzes der acetylsalicylsaeure und einer basischen aminosaeure und verfahren zu seiner herstellung
DE19709897A1 (de) Wismutsalze von Antibiotika der Moenomycin-Gruppe, Verfahren zu ihrer Herstellung, ihre Verwendung und solche Salze enthaltende Arzneimittel
DE2460929C2 (ko)
CH647677A5 (de) 4'-(acridinylamino)-methansulfon-anisidid enthaltende pharmazeutische zusammensetzung.
DE69115102T2 (de) Stabilisator für eine 4-ethyl-2-hydroxyimino-5-nitro-3-hexenamide enthaltende Zusammensetzung und Stabilisierungsverfahren.
DE60013583T2 (de) Verfahren zur herstellung von arzneimitteln eines basischen hydrophoben wirkstoffs
DE1965343A1 (de) Arzneimittel,insbesondere zur Herabsetzung der Schleimviskositaet und Anwendung als hustenstillendes Mittel,und Verfahren zu seiner Herstellung
DE2655130C3 (de) Eine praktisch lösungsmittelfreie Kristallform des Cefacetril-Natriumsalzes
DE2236876B2 (de) N-Substituierte Aminocarbonsäuren und diese Verbindungen enthaltende Arzneimittel
DE2461570C3 (de) Arzneimittel für die Behandlung bakterieller Infektionen der Augen und/oder der Ohren und Verfahren zu ihrer Herstellung
EP0061654B1 (de) Vincamin-cyclamat, Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel
DE1620177B2 (de) N-(2-Hydroxyäthyl) -piperazinocarboxymethyl-te tr acy elin, dessen pharmakologisch verwendbaren Salze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3203274A1 (de) Vitamin k(pfeil abwaerts)3(pfeil abwaerts)-(gamma)-cyclodextrin-einschlusskomplex, verfahren zu dessen herstellung und diesen einschlusskomplex enthaltende praeparate
CH648023A5 (de) 4'-(9-acridinylamino)methansulfon-m-anisidid-gluconat und dieses enthaltende mischungen.
DE69002027T2 (de) (3-Diethylaminopropyl)-1-amino-5-methyldipyrido[4,3-b][3,4-f]indoltrihydrochlorid.