DD202538A5 - Verfahren zur herstellung von substituierten harnstoffderivaten - Google Patents
Verfahren zur herstellung von substituierten harnstoffderivaten Download PDFInfo
- Publication number
- DD202538A5 DD202538A5 DD81236378A DD23637881A DD202538A5 DD 202538 A5 DD202538 A5 DD 202538A5 DD 81236378 A DD81236378 A DD 81236378A DD 23637881 A DD23637881 A DD 23637881A DD 202538 A5 DD202538 A5 DD 202538A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- alkyl
- water
- acetone
- general formula
- solvent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU803135A HU185294B (en) | 1980-12-29 | 1980-12-29 | Process for producing substituted urea derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DD202538A5 true DD202538A5 (de) | 1983-09-21 |
Family
ID=10962729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD81236378A DD202538A5 (de) | 1980-12-29 | 1981-12-29 | Verfahren zur herstellung von substituierten harnstoffderivaten |
Country Status (11)
Country | Link |
---|---|
US (1) | US4435567A (fr) |
JP (1) | JPS57171957A (fr) |
BR (1) | BR8108416A (fr) |
DD (1) | DD202538A5 (fr) |
DE (1) | DE3151685A1 (fr) |
FR (1) | FR2497199A1 (fr) |
GB (1) | GB2091257B (fr) |
HU (1) | HU185294B (fr) |
PL (1) | PL128520B1 (fr) |
SU (1) | SU1176834A3 (fr) |
YU (1) | YU308081A (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU185294B (en) | 1980-12-29 | 1984-12-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing substituted urea derivatives |
US4670041A (en) * | 1981-12-16 | 1987-06-02 | E. I. Du Pont De Nemours And Company | Oxabicycloalkane herbicides |
US4818271A (en) * | 1985-10-31 | 1989-04-04 | Fmc Corporation | Pyridinylurea compounds and agricultural uses |
US4837348A (en) * | 1986-04-30 | 1989-06-06 | Varian Associates, Inc. | Bonded phase chromatographic supports |
ES2062248T3 (es) * | 1989-11-10 | 1994-12-16 | Agrolinz Agrarchemikalien | Procedimiento para la obtencion de ureas puras, asimetricamente disubstituidas. |
DE3940261A1 (de) * | 1989-12-06 | 1991-06-13 | Agrolinz Agrarchemikalien Muen | Verfahren zur herstellung reiner, unsymmetrisch disubstituierter harnstoffe |
CA2308428A1 (fr) | 1997-11-03 | 1999-05-14 | Boehringer Ingelheim Pharmaceuticals, Inc. | Composes heterocycliques aromatiques convenant comme anti-inflammatoires |
EP1473292A1 (fr) * | 1997-11-03 | 2004-11-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Composes heterocycliques aromatiques convenant en tant qu'agents anti-inflammatoires |
UA73492C2 (en) | 1999-01-19 | 2005-08-15 | Aromatic heterocyclic compounds as antiinflammatory agents | |
WO2000050425A1 (fr) | 1999-02-22 | 2000-08-31 | Boehringer Ingelheim Pharmaceuticals, Inc. | Derives polycyclo heterocycliques utilises en tant qu'agents anti-inflammatoires |
JP2002539206A (ja) | 1999-03-12 | 2002-11-19 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | 抗炎症剤としての芳香族複素環化合物 |
JP4820488B2 (ja) | 1999-03-12 | 2011-11-24 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | 抗炎症薬として有用な化合物 |
ATE312823T1 (de) | 1999-07-09 | 2005-12-15 | Boehringer Ingelheim Pharma | Verfahren zur herstellung heteroarylsubstituierter ureaverbindungen |
EP1214293A1 (fr) * | 1999-09-08 | 2002-06-19 | Guilford Pharmaceuticals Inc. | Composes non-peptidiques de liaison cyclophiline et leur utilisation |
MXPA02004594A (es) | 1999-11-16 | 2002-10-23 | Boehringer Ingelheim Pharma | Derivados de urea como agentes anti-inflamatorios. |
US6525046B1 (en) | 2000-01-18 | 2003-02-25 | Boehringer Ingelheim Pharmaceuticals, Inc. | Aromatic heterocyclic compounds as antiinflammatory agents |
US6608052B2 (en) | 2000-02-16 | 2003-08-19 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compounds useful as anti-inflammatory agents |
US6656971B2 (en) | 2001-01-25 | 2003-12-02 | Guilford Pharmaceuticals Inc. | Trisubstituted carbocyclic cyclophilin binding compounds and their use |
CA2445003A1 (fr) | 2001-05-16 | 2002-11-21 | Boehringer Ingelheim Pharmaceuticals, Inc. | Derives de diaryluree utilisables en tant qu'agents anti-inflammatoires |
JP2004531571A (ja) | 2001-05-25 | 2004-10-14 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | サイトカイン生産のインヒビターとしてのカルバメート及びオキサミド化合物 |
AU2002366644A1 (en) * | 2001-12-11 | 2003-06-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for administering birb 796 bs |
ATE386030T1 (de) * | 2002-02-25 | 2008-03-15 | Boehringer Ingelheim Pharma | 1,4-disubstituierte benzokondensierte cycloalkyl- harnstoffverbindungen zur behandlung von zytokinvermittelten erkrankungen |
CA2817093A1 (fr) * | 2010-11-15 | 2012-05-24 | Abbvie Inc. | Inhibiteurs de nampt |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU184063B (en) * | 1979-11-08 | 1984-06-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing carbamoic-acid-phenyl-ester derivatives |
HU185294B (en) | 1980-12-29 | 1984-12-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing substituted urea derivatives |
-
1980
- 1980-12-29 HU HU803135A patent/HU185294B/hu unknown
-
1981
- 1981-12-24 GB GB8138962A patent/GB2091257B/en not_active Expired
- 1981-12-25 YU YU03080/81A patent/YU308081A/xx unknown
- 1981-12-28 SU SU813377199A patent/SU1176834A3/ru active
- 1981-12-28 JP JP56210117A patent/JPS57171957A/ja active Pending
- 1981-12-28 DE DE19813151685 patent/DE3151685A1/de active Granted
- 1981-12-28 US US06/334,470 patent/US4435567A/en not_active Expired - Fee Related
- 1981-12-28 BR BR8108416A patent/BR8108416A/pt unknown
- 1981-12-29 FR FR8124411A patent/FR2497199A1/fr active Granted
- 1981-12-29 PL PL1981234489A patent/PL128520B1/pl unknown
- 1981-12-29 DD DD81236378A patent/DD202538A5/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PL128520B1 (en) | 1984-02-29 |
SU1176834A3 (ru) | 1985-08-30 |
YU308081A (en) | 1983-10-31 |
GB2091257A (en) | 1982-07-28 |
BR8108416A (pt) | 1982-10-13 |
FR2497199B1 (fr) | 1984-06-29 |
HU185294B (en) | 1984-12-28 |
US4435567A (en) | 1984-03-06 |
DE3151685C2 (fr) | 1987-08-13 |
PL234489A1 (fr) | 1982-08-16 |
GB2091257B (en) | 1984-08-22 |
JPS57171957A (en) | 1982-10-22 |
FR2497199A1 (fr) | 1982-07-02 |
DE3151685A1 (de) | 1982-08-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ENJ | Ceased due to non-payment of renewal fee |