ES2062248T3 - Procedimiento para la obtencion de ureas puras, asimetricamente disubstituidas. - Google Patents

Procedimiento para la obtencion de ureas puras, asimetricamente disubstituidas.

Info

Publication number
ES2062248T3
ES2062248T3 ES90119673T ES90119673T ES2062248T3 ES 2062248 T3 ES2062248 T3 ES 2062248T3 ES 90119673 T ES90119673 T ES 90119673T ES 90119673 T ES90119673 T ES 90119673T ES 2062248 T3 ES2062248 T3 ES 2062248T3
Authority
ES
Spain
Prior art keywords
alkyl
unsubstituted
ureas
procedure
dialkylurea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90119673T
Other languages
English (en)
Inventor
Rudolf Helmut Dr Worther
Horst Korntner
Egmont Dr Auer
Kurt Dr Thonhofer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agrolinz Agrarchemikalien GmbH
Original Assignee
Agrolinz Agrarchemikalien GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agrolinz Agrarchemikalien GmbH filed Critical Agrolinz Agrarchemikalien GmbH
Application granted granted Critical
Publication of ES2062248T3 publication Critical patent/ES2062248T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety

Abstract

METODO PARA LA OBTENCION DE UREAS DISUBSTITUIDAS ASIMETRICAMENTE DE LA FORMULA GENERAL EN LA QUE R REPRESENTA UN RESTO DE FENILO NO SUBSTITUIDO O SUBSTITUIDO SIMPLE O MULTIPLEMENTE POR ATOMOS DE HALOGENO O GRUPOS DE ALCOILO, ALCOXI, ARILOXI O TRIFLUORMETILO, UN RESTO DE OXAZOLIL, ISOXAZOLIL, TIAZOLIL, ISOTIAZOLIL, BENZOXAZOLIL O BENZTIAZOLIL UNSUBSTITUIDO O SUBTITUIDO SIMPLE O MULTIPLEMENTE POR ATOMOS DE HALOGENOS O GRUPOS DE ALCOILO, ALCOXI, ARILOXI O TRIFLUORMETILO Y R SUB 1 Y R SUB 2 INDEPENDIENTEMENTE UNA DE OTRA REPRESENTAN UN ATOMO DE HIDROGENO O UN GRUPO ALCOILO, EN EL QUE R SUB 1 Y R SUB 2 NO SON SIMULTANEAMENTE HIDROGENO, O R SUB 1 Y R SUB 2 CONJUNTAMENTE REPRESENTAN UN GRUPO DE BUTILENO O DE PENTILENO, POR LA TRANSFORMACION DE UNA UREA N-ALCOILO O N, N-DIALCOILO CON UNA IGUALMENTE SUSTITUIDA ARILOAMINA O UNA AMINA HETEROCICLICA CON PRESENCIA DE AQUELLA AMINA QUE YA CONTENIA EL PRODUCTO DE PARTIDA, YA FUESE N-ALCOILO O UREA N, N-DIALCOILO.
ES90119673T 1989-11-10 1990-10-15 Procedimiento para la obtencion de ureas puras, asimetricamente disubstituidas. Expired - Lifetime ES2062248T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT257589 1989-11-10

Publications (1)

Publication Number Publication Date
ES2062248T3 true ES2062248T3 (es) 1994-12-16

Family

ID=3536751

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90119673T Expired - Lifetime ES2062248T3 (es) 1989-11-10 1990-10-15 Procedimiento para la obtencion de ureas puras, asimetricamente disubstituidas.

Country Status (15)

Country Link
US (1) US5099021A (es)
EP (1) EP0427963B1 (es)
JP (1) JPH03173860A (es)
CN (1) CN1025026C (es)
AT (1) ATE103589T1 (es)
CA (1) CA2028916A1 (es)
CZ (1) CZ282545B6 (es)
DE (1) DE59005183D1 (es)
DK (1) DK0427963T3 (es)
ES (1) ES2062248T3 (es)
FI (1) FI905532A0 (es)
HU (1) HU209386B (es)
IL (1) IL96049A (es)
PL (1) PL164621B1 (es)
SK (1) SK279982B6 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT394715B (de) * 1990-08-14 1992-06-10 Chemie Linz Gmbh Verfahren zur n-alkylierung von harnstoffen
US5241118A (en) * 1991-04-04 1993-08-31 Arco Chemical Technology, L.P. Process for the preparation of trisubstituted ureas by reductive carbonylation
AT397384B (de) * 1991-08-16 1994-03-25 Chemie Linz Gmbh Verfahren zur herstellung reiner n,n'-unsymmetrisch substituierter phenylharnstoffe
DE4130514A1 (de) * 1991-09-13 1993-03-18 Chemie Linz Deutschland Verfahren zur herstellung reiner n,n'-unsymmetrisch substituierter phenylharnstoffe
WO2000056725A1 (en) 1999-03-19 2000-09-28 Du Pont Pharmaceuticals Company N-adamant-1-yl-n'-[4-chlorobenzothiazol-2-yl] urea useful in the treatment of inflammation and as an anticancer radiosensitizing agent
AU8181701A (en) * 2000-06-21 2002-01-02 Hoffmann La Roche Benzothiazole derivatives
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
EA011279B1 (ru) 2004-05-24 2009-02-27 Ф. Хоффманн-Ля Рош Аг (4-метокси-7-морфолин-4-илбензотиазол-2-ил)-амид 4-гидрокси-4-метилпиперидин-1-карбоновой кислоты
EP1812392B1 (en) 2004-11-05 2008-07-09 F.Hoffmann-La Roche Ag Process for preparation of isonicotinic acid derivatives
BRPI0609719B8 (pt) 2005-03-23 2021-05-25 Hoffmann La Roche derivados de acetilenil-pirazol-pirimidina como antagonistas de mgbur2
CN101273040B (zh) 2005-09-27 2011-11-09 弗·哈夫曼-拉罗切有限公司 作为mglur2拮抗剂的*二唑基吡唑并嘧啶类化合物
WO2008077809A1 (en) * 2006-12-22 2008-07-03 F. Hoffmann-La Roche Ag Process for the manufacture of 7-oxa-bicyclo derivatives
HUP1100731A2 (en) 2011-12-30 2013-06-28 Stratoxer S Kft Complex forming compounds

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2673877A (en) * 1951-10-26 1954-03-30 Du Pont Preparation of chlorphenyldimethyl-ureas
DE1064051B (de) * 1958-04-09 1959-08-27 Basf Ag Verfahren zur Herstellung von substituierten Harnstoffen
NL277506A (es) * 1961-04-21
NL280954A (es) * 1961-07-14
NL129423C (es) * 1964-03-26
CH493195A (de) * 1968-01-23 1970-07-15 Ciba Geigy Schädlingsbekämpfungsmittel
CH505543A (de) * 1968-11-01 1971-04-15 Ciba Geigy Ag Schädlingsbekämpfungsmittel
DE2436139C3 (de) * 1973-07-26 1983-12-08 W.H. Dickinson Engineering Ltd., Southampton Konditioniervorrichtung für Tabak
US4212981A (en) * 1973-07-27 1980-07-15 Shionogi & Co., Ltd. Process for preparing 3-isoxazolylurea derivatives
JPS5810361B2 (ja) * 1974-10-04 1983-02-25 塩野義製薬株式会社 ３−アルチルイソオキサゾ−ル系除草剤
JPS6033109B2 (ja) * 1977-04-28 1985-08-01 塩野義製薬株式会社 尿素誘導体の合成法
DE2742158B2 (de) * 1977-09-19 1979-08-02 Skw Trostberg Ag, 8223 Trostberg Verfahren zur Herstellung substituierter Harnstoffe
EP0002881A1 (en) * 1977-11-02 1979-07-11 FISONS plc 5-Isoxazolylurea derivatives, their preparation, their use and compositions containing them
DE2844962A1 (de) * 1978-10-16 1980-04-30 Basf Ag Verfahren zur herstellung von symmetrischen 1,3-disubstituierten harnstoffen
DE2937331A1 (de) * 1979-09-14 1981-04-02 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von alkylharnstoffen
US4410697A (en) * 1980-01-25 1983-10-18 Reanal Finomvegyszergyar Process for the preparation of N-aryl-N'-(mono- or di substituted)-urea derivatives
HU185294B (en) * 1980-12-29 1984-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing substituted urea derivatives
US4380641A (en) * 1981-10-26 1983-04-19 Eli Lilly And Company Insecticidal oxazolyl ureas
JPS5939883A (ja) * 1982-08-27 1984-03-05 Shionogi & Co Ltd イソオキサゾ−ル系アシル尿素類
DE3413755A1 (de) * 1984-04-12 1985-10-24 Basf Ag, 6700 Ludwigshafen Thiazolylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
FR2577221B1 (fr) * 1985-02-11 1987-02-20 Rhone Poulenc Agrochimie Procede de preparation d'une phenyluree substituee
AU606696B2 (en) * 1987-06-25 1991-02-14 Dow Agrosciences Llc Process for preparing herbicidal and insecticidal ureas and carbamate derivatives

Also Published As

Publication number Publication date
EP0427963B1 (de) 1994-03-30
CZ282545B6 (cs) 1997-08-13
SK553590A3 (en) 1999-06-11
PL164621B1 (pl) 1994-08-31
CN1051726A (zh) 1991-05-29
PL287708A1 (en) 1991-11-04
CA2028916A1 (en) 1991-05-11
HU907086D0 (en) 1991-05-28
HU209386B (en) 1994-05-30
CZ553590A3 (en) 1997-06-11
SK279982B6 (sk) 1999-06-11
FI905532A0 (fi) 1990-11-08
US5099021A (en) 1992-03-24
ATE103589T1 (de) 1994-04-15
HUT55748A (en) 1991-06-28
DE59005183D1 (de) 1994-05-05
JPH03173860A (ja) 1991-07-29
CN1025026C (zh) 1994-06-15
IL96049A0 (en) 1991-07-18
DK0427963T3 (da) 1994-05-02
EP0427963A1 (de) 1991-05-22
IL96049A (en) 1994-10-21

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