JPS5359675A - Aminoalcohol derivatives - Google Patents
Aminoalcohol derivativesInfo
- Publication number
- JPS5359675A JPS5359675A JP13439876A JP13439876A JPS5359675A JP S5359675 A JPS5359675 A JP S5359675A JP 13439876 A JP13439876 A JP 13439876A JP 13439876 A JP13439876 A JP 13439876A JP S5359675 A JPS5359675 A JP S5359675A
- Authority
- JP
- Japan
- Prior art keywords
- aminoalcohol derivatives
- substd
- piperidine
- aminoalcohol
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001414 amino alcohols Chemical class 0.000 title abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 4
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005239 aroylamino group Chemical group 0.000 abstract 1
- 125000005333 aroyloxy group Chemical group 0.000 abstract 1
- QUOROGVXGVFFAY-UHFFFAOYSA-N n-[2-[4-[1-hydroxy-2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]phenyl]ethyl]acetamide Chemical compound C1=CC(CCNC(=O)C)=CC=C1C(O)CN1CCN(C=2C(=CC=CC=2)C)CC1 QUOROGVXGVFFAY-UHFFFAOYSA-N 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PURPOSE:Aminoalcohol derivatives of formula I (R is amino, OH, lower alkoxy, acyloxy, aroyloxy, acylamino, aroylamino; A is lower alkyleneF R<1> is H, acyl;H, lower alkyl; ring P is radical which together with N atom forms piperidine, 4-substd. piperidine or 4-substd. piperazine) and their acid addition salts, e.g. 1-(4-(2-acetamidoethyl)phenyl)-2-(4-(o-tolyl)-1-piperazinyl)-ethanol.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13439876A JPS5359675A (en) | 1976-11-08 | 1976-11-08 | Aminoalcohol derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13439876A JPS5359675A (en) | 1976-11-08 | 1976-11-08 | Aminoalcohol derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5359675A true JPS5359675A (en) | 1978-05-29 |
JPS612663B2 JPS612663B2 (en) | 1986-01-27 |
Family
ID=15127455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13439876A Granted JPS5359675A (en) | 1976-11-08 | 1976-11-08 | Aminoalcohol derivatives |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5359675A (en) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55153783A (en) * | 1979-05-04 | 1980-11-29 | Richardson Merrell Inc | 22hydroxyy55*11hydroxyy22*44*22oxoo11 benzimidazolinyl*piperidino*ethyl*benzoic acid derivatives |
US5185343A (en) * | 1989-05-17 | 1993-02-09 | Pfizer Inc. | Nortropyl-1-alkanol derivatives as antiischemic agents |
US5272160A (en) * | 1989-05-17 | 1993-12-21 | Pfizer Inc | 2-piperidino-1-alkanol derivatives as antiischemic agents |
US5527912A (en) * | 1991-10-23 | 1996-06-18 | Pfizer Inc. | Intermediates for 2-piperidino-1-alkanol derivatives |
US5710168A (en) * | 1991-10-23 | 1998-01-20 | Pfizer Inc. | 2-piperidino-1-alkanol derivatives as neuroprotective agents |
US6046213A (en) * | 1994-08-18 | 2000-04-04 | Pfizer Inc. | Neuroprotective 3-(piperidinyl-1)-chroman-4,7-diol and 1-(4-hydroxyphenyl)-2-(piperidinyl-1)-alkanol derivatives |
US7601868B2 (en) | 2003-02-12 | 2009-10-13 | Takeda Pharmaceutical Company Limited | Amine derivative |
WO2010072144A1 (en) * | 2008-12-23 | 2010-07-01 | 江苏恩华药业股份有限公司 | Substituted phenylpiperazinyl aralkylalcohol derivatives, pharmaceutical compositions containing such derivatives and uses thereof |
USRE45198E1 (en) | 1996-01-04 | 2014-10-14 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6453172U (en) * | 1987-09-28 | 1989-04-03 |
-
1976
- 1976-11-08 JP JP13439876A patent/JPS5359675A/en active Granted
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55153783A (en) * | 1979-05-04 | 1980-11-29 | Richardson Merrell Inc | 22hydroxyy55*11hydroxyy22*44*22oxoo11 benzimidazolinyl*piperidino*ethyl*benzoic acid derivatives |
US5185343A (en) * | 1989-05-17 | 1993-02-09 | Pfizer Inc. | Nortropyl-1-alkanol derivatives as antiischemic agents |
US5272160A (en) * | 1989-05-17 | 1993-12-21 | Pfizer Inc | 2-piperidino-1-alkanol derivatives as antiischemic agents |
US5338754A (en) * | 1989-05-17 | 1994-08-16 | Pfizer Inc | 2-pyrrolidino-1-alkanol derivatives as antiischemic agents |
US5391742A (en) * | 1989-05-17 | 1995-02-21 | Pfizer Inc. | Intermediates for 2-piperidino-1-alkanols |
US5710168A (en) * | 1991-10-23 | 1998-01-20 | Pfizer Inc. | 2-piperidino-1-alkanol derivatives as neuroprotective agents |
US5527912A (en) * | 1991-10-23 | 1996-06-18 | Pfizer Inc. | Intermediates for 2-piperidino-1-alkanol derivatives |
US6046213A (en) * | 1994-08-18 | 2000-04-04 | Pfizer Inc. | Neuroprotective 3-(piperidinyl-1)-chroman-4,7-diol and 1-(4-hydroxyphenyl)-2-(piperidinyl-1)-alkanol derivatives |
USRE45198E1 (en) | 1996-01-04 | 2014-10-14 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US7601868B2 (en) | 2003-02-12 | 2009-10-13 | Takeda Pharmaceutical Company Limited | Amine derivative |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
WO2010072144A1 (en) * | 2008-12-23 | 2010-07-01 | 江苏恩华药业股份有限公司 | Substituted phenylpiperazinyl aralkylalcohol derivatives, pharmaceutical compositions containing such derivatives and uses thereof |
US8778948B2 (en) | 2008-12-23 | 2014-07-15 | NHWA Pharma, Corporation | Substituted phenylpiperazinyl aralkylalcohol derivatives, pharmaceutical compositions containing such derivatives and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
JPS612663B2 (en) | 1986-01-27 |
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