DD152935A5 - Substituierte beta-carbolin-3-carbonsaeure-derivate - Google Patents
Substituierte beta-carbolin-3-carbonsaeure-derivate Download PDFInfo
- Publication number
- DD152935A5 DD152935A5 DD80223673A DD22367380A DD152935A5 DD 152935 A5 DD152935 A5 DD 152935A5 DD 80223673 A DD80223673 A DD 80223673A DD 22367380 A DD22367380 A DD 22367380A DD 152935 A5 DD152935 A5 DD 152935A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- carboline
- carboxylic acid
- compound
- general formula
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK362279 | 1979-08-29 | ||
DK88980A DK88980A (da) | 1980-02-29 | 1980-02-29 | Beta-carbonline-3-carboxylsyrederivater og fremgangsmaader til fremstilling af samme |
DE19803015816 DE3015816A1 (de) | 1980-04-22 | 1980-04-22 | 4-substituierte- (beta) -carbolin-3-carbonsaeurederivate, ihre herstellung und verwendung |
DE19803023567 DE3023567A1 (de) | 1980-06-20 | 1980-06-20 | Substituierte (beta) -carbolin-3-carbonsaeurederivate |
Publications (1)
Publication Number | Publication Date |
---|---|
DD152935A5 true DD152935A5 (de) | 1981-12-16 |
Family
ID=27432526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD80223673A DD152935A5 (de) | 1979-08-29 | 1980-08-29 | Substituierte beta-carbolin-3-carbonsaeure-derivate |
Country Status (16)
Country | Link |
---|---|
US (2) | US4371536A (xx) |
EP (1) | EP0030254B1 (xx) |
CA (1) | CA1150246A (xx) |
DD (1) | DD152935A5 (xx) |
DE (1) | DE3069559D1 (xx) |
ES (1) | ES8106305A1 (xx) |
FI (1) | FI68829C (xx) |
HU (1) | HU186744B (xx) |
IE (1) | IE50229B1 (xx) |
IL (1) | IL60906A (xx) |
NO (1) | NO155055C (xx) |
NZ (1) | NZ194747A (xx) |
PL (1) | PL226479A1 (xx) |
PT (1) | PT71744B (xx) |
RO (1) | RO80265B (xx) |
YU (1) | YU215580A (xx) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ194747A (en) * | 1979-08-29 | 1988-11-29 | Schering Ag | 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives |
JPS57123180A (en) * | 1980-12-17 | 1982-07-31 | Schering Ag | 3-substituted beta-carboline, manufacture and psychotropic drug containing same |
DE3240514A1 (de) * | 1982-10-29 | 1984-05-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Ss-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
DE3240513A1 (de) * | 1982-10-29 | 1984-05-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung |
DK149270C (da) * | 1983-05-27 | 1986-08-25 | Schering Ag | Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater |
DE3322894A1 (de) * | 1983-06-23 | 1985-01-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue (beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel (h) |
DE3322895A1 (de) * | 1983-06-23 | 1985-01-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s) |
DE3335323A1 (de) | 1983-09-27 | 1985-04-04 | Schering AG, 1000 Berlin und 4709 Bergkamen | Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
FR2555988A1 (fr) * | 1983-12-06 | 1985-06-07 | Centre Nat Rech Scient | Derive de b-carbolines, procede pour leurs preparations et medicament les contenant |
DK240184D0 (da) * | 1984-05-15 | 1984-05-15 | Ferrosan As | Beta-carboline-3-carboxylic acid derivatives and method of preparing the same |
DE3535928A1 (de) * | 1985-10-04 | 1987-04-09 | Schering Ag | Tetrahydro-(beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE3545776A1 (de) * | 1985-12-20 | 1987-06-25 | Schering Ag | 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel |
DE3609699A1 (de) * | 1986-03-20 | 1987-09-24 | Schering Ag | 5- oder 6-substituierte-(beta)-carbolin-3-carbonsaeureester |
DE3608089A1 (de) * | 1986-03-08 | 1987-09-10 | Schering Ag | Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel |
DE3752373T2 (de) * | 1986-10-13 | 2004-03-25 | Asahi Kasei Kogyo K.K. | Pyridin-derivate |
DE4029389A1 (de) * | 1990-09-13 | 1992-03-26 | Schering Ag | Verfahren zur herstellung von (beta)-carbolin-derivaten |
US5350750A (en) * | 1991-04-27 | 1994-09-27 | Schering Aktiengesellschaft | β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives, process for their production and their use in pharmaceutical agents |
GB9508195D0 (en) * | 1995-04-20 | 1995-06-07 | Univ British Columbia | Novel biologically active compounds and compositions,their use and derivation |
ATE212549T1 (de) * | 1996-04-04 | 2002-02-15 | Hoffmann La Roche | Verwendung von tetrahydrobetacarbolin-derivaten zur vorbeugung der metastasenbildung |
ES2194213T3 (es) * | 1996-08-09 | 2003-11-16 | Boehringer Ingelheim Pharma | Beta-carbolinas-4- sustituidas en calidad de inmunomoduladores. |
UA74826C2 (en) | 2000-05-17 | 2006-02-15 | Ortho Mcneil Pharm Inc | ?-carboline derivatives as phosphodiesterase inhibitors |
AR036040A1 (es) | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
HUP0402289A2 (hu) | 2001-10-02 | 2005-02-28 | Pharmacia & Upjohn Company | Gyógyhatású azabiciklusos csoporttal helyettesített kondenzált heteroaril-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk |
MXPA04004373A (es) | 2001-11-09 | 2004-08-11 | Upjohn Co | Compuestos heterociclicos condensados con fenilo azabiciclo para el tratamiento de enfermedades. |
US20030176456A1 (en) * | 2001-12-21 | 2003-09-18 | June Harry L. | Methods for reducing alcohol cravings in chronic alcoholics |
US6858613B2 (en) | 2002-02-19 | 2005-02-22 | Pfizer Inc. | Fused bicyclic-N-bridged-heteroaromatic carboxamides for the treatment of disease |
PA8586801A1 (es) | 2002-10-31 | 2005-02-04 | Pfizer | Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso |
MXPA05007563A (es) | 2003-01-27 | 2005-09-21 | Pfizer | Inhibidores de la integrasa del vih, composiciones farmaceuticas y metodos para su uso. |
CN100503607C (zh) | 2003-06-02 | 2009-06-24 | 新疆华世丹药物研究有限责任公司 | 去氢骆驼蓬碱衍生物类化合物及其应用 |
EP1756103A2 (en) | 2004-04-26 | 2007-02-28 | Pfizer, Inc. | Pyrrolopyridine derivatives and their use as hiv-integrase inhibitors |
ES2292123T3 (es) * | 2004-04-26 | 2008-03-01 | Pfizer Inc. | Inhibidores de la enzima integrasa de vih. |
EA200800758A1 (ru) * | 2005-10-07 | 2008-08-29 | Пфайзер Продактс Инк. | Ингибиторы фермента интегразы вич |
WO2008055068A2 (en) * | 2006-10-28 | 2008-05-08 | Methylgene Inc. | Inhibitors of histone deacetylase |
AU2013205135B2 (en) * | 2006-10-28 | 2015-11-05 | Forum Pharmaceuticals Inc. | Inhibitors of histone deacetylase |
EP2307410A1 (en) * | 2008-05-22 | 2011-04-13 | The UWM Research Foundation, Inc | Aza-beta-carbolines and methods of using same |
CN104211699A (zh) * | 2013-06-05 | 2014-12-17 | 首都医科大学 | β-咔啉衍生物,其制备,纳米结构,抗肿瘤活性和应用 |
CN104628722B (zh) * | 2015-01-30 | 2016-06-22 | 华南农业大学 | 一种骆驼蓬碱酰胺类化合物及其制备方法和应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA786351A (en) * | 1968-05-28 | Leonard Frederick | PROCESS FOR THE PREPARATION OF NEW .beta.-CARBOLIN-CARBOXYLIC ACID AMIDE DERIVATIVES | |
ES273769A1 (es) * | 1961-01-18 | 1962-06-01 | Geigy Ag J R | Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico |
GB1084257A (xx) * | 1963-11-06 | |||
NZ194747A (en) * | 1979-08-29 | 1988-11-29 | Schering Ag | 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives |
JPS57123180A (en) * | 1980-12-17 | 1982-07-31 | Schering Ag | 3-substituted beta-carboline, manufacture and psychotropic drug containing same |
DE3322894A1 (de) * | 1983-06-23 | 1985-01-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue (beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel (h) |
DK240184D0 (da) * | 1984-05-15 | 1984-05-15 | Ferrosan As | Beta-carboline-3-carboxylic acid derivatives and method of preparing the same |
DK240084D0 (da) * | 1984-05-15 | 1984-05-15 | Ferrosan As | New beta-carboline-3-oxadiazolyl derivatives |
DE3504045A1 (de) * | 1985-02-04 | 1986-08-07 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur herstellung von ss-carbolinen durch dehydrierung |
-
1980
- 1980-08-22 NZ NZ194747A patent/NZ194747A/xx unknown
- 1980-08-23 EP EP80105019A patent/EP0030254B1/en not_active Expired
- 1980-08-23 DE DE8080105019T patent/DE3069559D1/de not_active Expired
- 1980-08-25 IL IL60906A patent/IL60906A/xx unknown
- 1980-08-27 PT PT71744A patent/PT71744B/pt unknown
- 1980-08-27 RO RO102050A patent/RO80265B/ro unknown
- 1980-08-28 IE IE1806/80A patent/IE50229B1/en not_active IP Right Cessation
- 1980-08-28 US US06/182,244 patent/US4371536A/en not_active Expired - Lifetime
- 1980-08-28 CA CA000359184A patent/CA1150246A/en not_active Expired
- 1980-08-28 YU YU02155/80A patent/YU215580A/xx unknown
- 1980-08-28 NO NO802546A patent/NO155055C/no unknown
- 1980-08-28 FI FI802720A patent/FI68829C/fi not_active IP Right Cessation
- 1980-08-28 HU HU802129A patent/HU186744B/hu unknown
- 1980-08-29 PL PL22647980A patent/PL226479A1/xx unknown
- 1980-08-29 DD DD80223673A patent/DD152935A5/de unknown
- 1980-08-29 ES ES494590A patent/ES8106305A1/es not_active Expired
-
1988
- 1988-04-25 US US07/188,145 patent/US5010077A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES494590A0 (es) | 1981-08-16 |
PL226479A1 (xx) | 1981-10-30 |
IE801806L (en) | 1981-02-28 |
EP0030254B1 (en) | 1984-10-31 |
IL60906A0 (en) | 1980-10-26 |
HU186744B (en) | 1985-09-30 |
FI802720A (fi) | 1981-03-01 |
NO802546L (no) | 1981-03-02 |
IL60906A (en) | 1985-11-29 |
NO155055B (no) | 1986-10-27 |
ES8106305A1 (es) | 1981-08-16 |
DE3069559D1 (en) | 1984-12-06 |
US4371536A (en) | 1983-02-01 |
NO155055C (no) | 1987-02-04 |
FI68829C (fi) | 1985-11-11 |
NZ194747A (en) | 1988-11-29 |
YU215580A (en) | 1984-02-29 |
FI68829B (fi) | 1985-07-31 |
RO80265B (ro) | 1983-04-30 |
PT71744B (en) | 1981-06-08 |
US5010077A (en) | 1991-04-23 |
IE50229B1 (en) | 1986-03-05 |
CA1150246A (en) | 1983-07-19 |
EP0030254A1 (en) | 1981-06-17 |
PT71744A (en) | 1980-09-01 |
RO80265A (ro) | 1983-04-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DD152935A5 (de) | Substituierte beta-carbolin-3-carbonsaeure-derivate | |
DE3144455C2 (xx) | ||
EP1427730A1 (de) | Neue dihydropteridinone, verfahren zu deren herstellung und deren verwendung als arzneimittel | |
EP0148440B1 (de) | 1,3,4,5-Tetrahydrobenz[c,d]indole, ein Verfahren zu ihrer Herstellung und ihre Verwendung | |
WO1994018199A1 (de) | Imidazopyridine und ihre anwendung zur behandlung von magen-darm krankheiten | |
EP0882049A1 (de) | Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo- 4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate | |
DD211555A5 (de) | Verfahren zur herstellung neuer 4-amino-6,7-dimethoxychinolin-derivate | |
DE60214359T2 (de) | Stickstoffbasierte camptothecin-derivate | |
DD155988A5 (de) | Verfahren zur herstellung von 2-acylaminomethyl-1,4-benzodiazepine und deren salze | |
DD224851A5 (de) | Verfahren zur herstellung von imidazolen | |
DE2815724A1 (de) | Indolderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel | |
DD146705A5 (de) | Verfahren zur herstellung von 3,4-dihydro-3-oxo-2-chinoxalinen | |
DE2839279A1 (de) | Derivate des 1,2,3,3a,8,8a-hexahydropyrrolo eckige klammer auf 2,3-b eckige klammer zu indols, verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel | |
DE3153221C2 (xx) | ||
DD236928A5 (de) | Verfahren zur herstellung neuer 1,2,4-triazolo-carbamate | |
DE2841126A1 (de) | Pyrimido eckige klammer auf 2,1-a eckige klammer zu isochinolinderivate, verfahren zu ihrer herstellung und pharmazeutische mittel, die diese verbindungen enthalten | |
DD202563A5 (de) | Verfahren zur herstellung von 1,5-diphenylpyrazolin-3-on-verbindungen | |
EP0266308B1 (de) | Indolo-pyrazino-benzodiazepin-Derivate | |
EP0138034B1 (de) | Substituierte Pyrido(1,2-c)imidazo((1,2-a)benzimidazole, Verfahren zu ihrer Herstellung, ihre Verwendung sowie pharmazeutische Präparate auf Basis dieser Verbindungen | |
DE2259471C2 (de) | 2-Halogen-9-phenyl-5,6-dihydro-7H-pyrido [2,3-f] [1,4] diazepinderivate | |
JPS62169783A (ja) | イミダゾ〔1,2−a〕キノリン誘導体、その製造法およびその医薬への応用 | |
DE3048264A1 (de) | 2-acylaminomethyl-1,4-benzodiazepine und deren salze sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel | |
DE2357253A1 (de) | Neue chinolinderivate | |
AT390791B (de) | Verfahren zur herstellung neuer kondensierter as-triazinium-derivate sowie von deren isomeren | |
DE2042758A1 (de) | Verfahren zur Herstellung von Benzodiazepinderivaten |