NO802546L - Fremgangsmaate ved fremstilling av beta-carbolin-3-carboxylsyre-derivater. - Google Patents
Fremgangsmaate ved fremstilling av beta-carbolin-3-carboxylsyre-derivater.Info
- Publication number
- NO802546L NO802546L NO802546A NO802546A NO802546L NO 802546 L NO802546 L NO 802546L NO 802546 A NO802546 A NO 802546A NO 802546 A NO802546 A NO 802546A NO 802546 L NO802546 L NO 802546L
- Authority
- NO
- Norway
- Prior art keywords
- carbolin
- procedure
- carboxylic acid
- acid derivatives
- preparing beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK362279 | 1979-08-29 | ||
DK88980A DK88980A (da) | 1980-02-29 | 1980-02-29 | Beta-carbonline-3-carboxylsyrederivater og fremgangsmaader til fremstilling af samme |
DE19803015816 DE3015816A1 (de) | 1980-04-22 | 1980-04-22 | 4-substituierte- (beta) -carbolin-3-carbonsaeurederivate, ihre herstellung und verwendung |
DE19803023567 DE3023567A1 (de) | 1980-06-20 | 1980-06-20 | Substituierte (beta) -carbolin-3-carbonsaeurederivate |
Publications (3)
Publication Number | Publication Date |
---|---|
NO802546L true NO802546L (no) | 1981-03-02 |
NO155055B NO155055B (no) | 1986-10-27 |
NO155055C NO155055C (no) | 1987-02-04 |
Family
ID=27432526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO802546A NO155055C (no) | 1979-08-29 | 1980-08-28 | Analogifremgangsmaate ved fremstilling av terapeutisk aktive beta-carbolin-3-carboxylsyrederivater. |
Country Status (16)
Country | Link |
---|---|
US (2) | US4371536A (no) |
EP (1) | EP0030254B1 (no) |
CA (1) | CA1150246A (no) |
DD (1) | DD152935A5 (no) |
DE (1) | DE3069559D1 (no) |
ES (1) | ES494590A0 (no) |
FI (1) | FI68829C (no) |
HU (1) | HU186744B (no) |
IE (1) | IE50229B1 (no) |
IL (1) | IL60906A (no) |
NO (1) | NO155055C (no) |
NZ (1) | NZ194747A (no) |
PL (1) | PL226479A1 (no) |
PT (1) | PT71744B (no) |
RO (1) | RO80265B (no) |
YU (1) | YU215580A (no) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ194747A (en) * | 1979-08-29 | 1988-11-29 | Schering Ag | 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives |
JPS57123180A (en) * | 1980-12-17 | 1982-07-31 | Schering Ag | 3-substituted beta-carboline, manufacture and psychotropic drug containing same |
DE3240514A1 (de) * | 1982-10-29 | 1984-05-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Ss-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
DE3240513A1 (de) * | 1982-10-29 | 1984-05-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung |
DK149270C (da) * | 1983-05-27 | 1986-08-25 | Schering Ag | Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater |
DE3322894A1 (de) * | 1983-06-23 | 1985-01-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue (beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel (h) |
DE3322895A1 (de) * | 1983-06-23 | 1985-01-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s) |
DE3335323A1 (de) * | 1983-09-27 | 1985-04-04 | Schering AG, 1000 Berlin und 4709 Bergkamen | Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
FR2555988A1 (fr) * | 1983-12-06 | 1985-06-07 | Centre Nat Rech Scient | Derive de b-carbolines, procede pour leurs preparations et medicament les contenant |
DK240184D0 (da) * | 1984-05-15 | 1984-05-15 | Ferrosan As | Beta-carboline-3-carboxylic acid derivatives and method of preparing the same |
DE3535928A1 (de) * | 1985-10-04 | 1987-04-09 | Schering Ag | Tetrahydro-(beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE3545776A1 (de) * | 1985-12-20 | 1987-06-25 | Schering Ag | 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel |
DE3609699A1 (de) * | 1986-03-20 | 1987-09-24 | Schering Ag | 5- oder 6-substituierte-(beta)-carbolin-3-carbonsaeureester |
DE3608089A1 (de) * | 1986-03-08 | 1987-09-10 | Schering Ag | Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel |
EP0285671B1 (en) * | 1986-10-13 | 2003-09-03 | Asahi Kasei Kabushiki Kaisha | Pyridine derivatives |
DE4029389A1 (de) * | 1990-09-13 | 1992-03-26 | Schering Ag | Verfahren zur herstellung von (beta)-carbolin-derivaten |
US5350750A (en) * | 1991-04-27 | 1994-09-27 | Schering Aktiengesellschaft | β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives, process for their production and their use in pharmaceutical agents |
GB9508195D0 (en) * | 1995-04-20 | 1995-06-07 | Univ British Columbia | Novel biologically active compounds and compositions,their use and derivation |
CN1113648C (zh) * | 1996-04-04 | 2003-07-09 | 弗·哈夫曼-拉罗切有限公司 | 四氢-β-咔啉衍生物作为抗转移瘤剂的用途 |
ES2194213T3 (es) * | 1996-08-09 | 2003-11-16 | Boehringer Ingelheim Pharma | Beta-carbolinas-4- sustituidas en calidad de inmunomoduladores. |
UA74826C2 (en) | 2000-05-17 | 2006-02-15 | Ortho Mcneil Pharm Inc | ?-carboline derivatives as phosphodiesterase inhibitors |
AR036040A1 (es) * | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
IL160884A0 (en) | 2001-10-02 | 2004-08-31 | Upjohn Co | Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease |
JP2005510523A (ja) | 2001-11-09 | 2005-04-21 | ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー | アザ二環式フェニル縮合複素環式化合物、及びα7NACHRリガンドとしての当該化合物の使用 |
US20030176456A1 (en) * | 2001-12-21 | 2003-09-18 | June Harry L. | Methods for reducing alcohol cravings in chronic alcoholics |
AU2003219690A1 (en) | 2002-02-19 | 2003-09-09 | Pharmacia And Upjohn Company | Fused bicyclic-n-bridged-heteroaromatic carboxamides for the treatment of disease |
PA8586801A1 (es) * | 2002-10-31 | 2005-02-04 | Pfizer | Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso |
BRPI0407052A (pt) * | 2003-01-27 | 2006-01-17 | Pfizer | Inibidores da hiv-integrase, composições farmacêuticas, e métodos para sua utilização |
CN100503607C (zh) * | 2003-06-02 | 2009-06-24 | 新疆华世丹药物研究有限责任公司 | 去氢骆驼蓬碱衍生物类化合物及其应用 |
JP2007534738A (ja) | 2004-04-26 | 2007-11-29 | ファイザー・インク | Hivインテグラーゼ酵素の阻害剤 |
JP2007534739A (ja) | 2004-04-26 | 2007-11-29 | ファイザー・インク | ピロロピリジン誘導体及びhivインテグラーゼ酵素阻害剤としてのその使用 |
KR20080042171A (ko) * | 2005-10-07 | 2008-05-14 | 화이자 프로덕츠 인코포레이티드 | Hiv 인테그라제 효소의 억제제 |
KR101312993B1 (ko) * | 2006-10-28 | 2013-11-25 | 엔비보 파마슈티칼즈, 인코퍼레이티드 | 히스톤 데아세틸라아제의 억제제 |
AU2013205135B2 (en) * | 2006-10-28 | 2015-11-05 | Forum Pharmaceuticals Inc. | Inhibitors of histone deacetylase |
EP2307410A1 (en) * | 2008-05-22 | 2011-04-13 | The UWM Research Foundation, Inc | Aza-beta-carbolines and methods of using same |
CN104211699A (zh) * | 2013-06-05 | 2014-12-17 | 首都医科大学 | β-咔啉衍生物,其制备,纳米结构,抗肿瘤活性和应用 |
CN104628722B (zh) * | 2015-01-30 | 2016-06-22 | 华南农业大学 | 一种骆驼蓬碱酰胺类化合物及其制备方法和应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA786351A (en) * | 1968-05-28 | Leonard Frederick | PROCESS FOR THE PREPARATION OF NEW .beta.-CARBOLIN-CARBOXYLIC ACID AMIDE DERIVATIVES | |
ES273769A1 (es) * | 1961-01-18 | 1962-06-01 | Geigy Ag J R | Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico |
GB1084256A (no) * | 1963-11-06 | |||
NZ194747A (en) * | 1979-08-29 | 1988-11-29 | Schering Ag | 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives |
JPS57123180A (en) * | 1980-12-17 | 1982-07-31 | Schering Ag | 3-substituted beta-carboline, manufacture and psychotropic drug containing same |
DE3322894A1 (de) * | 1983-06-23 | 1985-01-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue (beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel (h) |
DK240184D0 (da) * | 1984-05-15 | 1984-05-15 | Ferrosan As | Beta-carboline-3-carboxylic acid derivatives and method of preparing the same |
DK240084D0 (da) * | 1984-05-15 | 1984-05-15 | Ferrosan As | New beta-carboline-3-oxadiazolyl derivatives |
DE3504045A1 (de) * | 1985-02-04 | 1986-08-07 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur herstellung von ss-carbolinen durch dehydrierung |
-
1980
- 1980-08-22 NZ NZ194747A patent/NZ194747A/xx unknown
- 1980-08-23 DE DE8080105019T patent/DE3069559D1/de not_active Expired
- 1980-08-23 EP EP80105019A patent/EP0030254B1/en not_active Expired
- 1980-08-25 IL IL60906A patent/IL60906A/xx unknown
- 1980-08-27 RO RO102050A patent/RO80265B/ro unknown
- 1980-08-27 PT PT71744A patent/PT71744B/pt unknown
- 1980-08-28 FI FI802720A patent/FI68829C/fi not_active IP Right Cessation
- 1980-08-28 YU YU02155/80A patent/YU215580A/xx unknown
- 1980-08-28 IE IE1806/80A patent/IE50229B1/en not_active IP Right Cessation
- 1980-08-28 US US06/182,244 patent/US4371536A/en not_active Expired - Lifetime
- 1980-08-28 HU HU802129A patent/HU186744B/hu unknown
- 1980-08-28 CA CA000359184A patent/CA1150246A/en not_active Expired
- 1980-08-28 NO NO802546A patent/NO155055C/no unknown
- 1980-08-29 ES ES494590A patent/ES494590A0/es active Granted
- 1980-08-29 PL PL22647980A patent/PL226479A1/xx unknown
- 1980-08-29 DD DD80223673A patent/DD152935A5/de unknown
-
1988
- 1988-04-25 US US07/188,145 patent/US5010077A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PT71744A (en) | 1980-09-01 |
ES8106305A1 (es) | 1981-08-16 |
NO155055B (no) | 1986-10-27 |
EP0030254B1 (en) | 1984-10-31 |
FI68829B (fi) | 1985-07-31 |
ES494590A0 (es) | 1981-08-16 |
US5010077A (en) | 1991-04-23 |
EP0030254A1 (en) | 1981-06-17 |
IL60906A (en) | 1985-11-29 |
FI68829C (fi) | 1985-11-11 |
NZ194747A (en) | 1988-11-29 |
HU186744B (en) | 1985-09-30 |
PL226479A1 (no) | 1981-10-30 |
IE801806L (en) | 1981-02-28 |
NO155055C (no) | 1987-02-04 |
DE3069559D1 (en) | 1984-12-06 |
IL60906A0 (en) | 1980-10-26 |
YU215580A (en) | 1984-02-29 |
US4371536A (en) | 1983-02-01 |
CA1150246A (en) | 1983-07-19 |
DD152935A5 (de) | 1981-12-16 |
RO80265A (ro) | 1983-04-29 |
FI802720A (fi) | 1981-03-01 |
PT71744B (en) | 1981-06-08 |
RO80265B (ro) | 1983-04-30 |
IE50229B1 (en) | 1986-03-05 |
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