DD142712A5 - Verfahren zur herstellung neuer mercaptoimidazolderivate - Google Patents
Verfahren zur herstellung neuer mercaptoimidazolderivate Download PDFInfo
- Publication number
- DD142712A5 DD142712A5 DD79212098A DD21209879A DD142712A5 DD 142712 A5 DD142712 A5 DD 142712A5 DD 79212098 A DD79212098 A DD 79212098A DD 21209879 A DD21209879 A DD 21209879A DD 142712 A5 DD142712 A5 DD 142712A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- phenyl
- formula
- pyridyl
- acid addition
- items
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU79412 | 1978-04-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD142712A5 true DD142712A5 (de) | 1980-07-09 |
Family
ID=19728887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD79212098A DD142712A5 (de) | 1978-04-11 | 1979-04-09 | Verfahren zur herstellung neuer mercaptoimidazolderivate |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US4461770A (da) |
| EP (1) | EP0004648B1 (da) |
| JP (1) | JPS54135769A (da) |
| KR (2) | KR820002314B1 (da) |
| AT (1) | AT376971B (da) |
| AU (1) | AU532402B2 (da) |
| CS (1) | CS220324B2 (da) |
| CY (1) | CY1302A (da) |
| DD (1) | DD142712A5 (da) |
| DE (1) | DE2963572D1 (da) |
| DK (1) | DK148879A (da) |
| ES (5) | ES8303355A1 (da) |
| FI (1) | FI65066C (da) |
| GR (1) | GR71193B (da) |
| HK (1) | HK87285A (da) |
| HU (1) | HU182018B (da) |
| IL (1) | IL57040A (da) |
| MY (1) | MY8600271A (da) |
| NO (1) | NO148926C (da) |
| NZ (1) | NZ190153A (da) |
| PL (2) | PL125882B1 (da) |
| PT (1) | PT69460A (da) |
| SU (2) | SU1259962A3 (da) |
| ZA (1) | ZA791702B (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2823197A1 (de) * | 1978-05-24 | 1979-11-29 | Schering Ag | Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| DE2856909A1 (de) * | 1978-12-28 | 1980-07-17 | Schering Ag | Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| DE3025484A1 (de) * | 1980-07-03 | 1982-02-04 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| US4686231A (en) * | 1985-12-12 | 1987-08-11 | Smithkline Beckman Corporation | Inhibition of 5-lipoxygenase products |
| US4780470A (en) * | 1986-08-19 | 1988-10-25 | Smithkline Beckman Corporation | Inhibition of interleukin-1 by monocytes and/or macrophages |
| FI91754C (fi) * | 1986-12-02 | 1994-08-10 | Tanabe Seiyaku Co | Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi |
| US5955480A (en) * | 1996-11-20 | 1999-09-21 | Merck & Co., Inc. | Triaryl substituted imidazoles, compositions containing such compounds and methods of use |
| CA2297176A1 (en) * | 1997-04-24 | 1998-10-29 | Ortho-Mcneil Pharmaceutical, Inc. | Substituted imidazoles useful in the treatment of inflammatory diseases |
| JP2002515915A (ja) * | 1997-06-30 | 2002-05-28 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 炎症性疾患の治療で有用な２−置換イミダゾール類 |
| DE19842833B4 (de) | 1998-09-18 | 2005-04-14 | Merckle Gmbh | 2-Arylalkylthio-imidazole, 2-Arylalkenylthio-imidazole und 2-Arylalkinylthio-imidazole als Entzündungs-Hemmstoffe und Hemmstoffe der Cytokin-Freisetzung |
| DE10107683A1 (de) * | 2001-02-19 | 2002-08-29 | Merckle Gmbh Chem Pharm Fabrik | 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie |
| DE10238045A1 (de) * | 2002-08-20 | 2004-03-04 | Merckle Gmbh Chem.-Pharm. Fabrik | 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie |
| US8134029B2 (en) | 2002-09-16 | 2012-03-13 | Sunovion Pharmaceuticals Inc. | Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine |
| MX2008000250A (es) | 2005-07-06 | 2008-03-19 | Sepracor Inc | Combinaciones de eszopiclona y trans-4-(3,4-diclorofenil)-1,2,3,4- tetrahidro-n-metil-1-naftalenamina o trans 4-(3,4-diclorofenil)-1, 2,3,4-tetrahidro-1-naftalenamina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y |
| CA2648121C (en) | 2006-03-31 | 2013-08-06 | Sepracor Inc. | Preparation of chiral amides and amines |
| EP1894925A1 (en) * | 2006-08-24 | 2008-03-05 | Merckle Gmbh | Imidazole compounds having an antiinflammatory effect |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2981739A (en) * | 1958-01-27 | 1961-04-25 | Diamond Alkali Co | Certain alpha-haloaldehyde addition products of ethylenethioureas and process |
| US3714179A (en) * | 1970-09-08 | 1973-01-30 | Searle & Co | 1-alkyl-2-furfurylthioimidazoles and congeners |
| JPS5343958B2 (da) * | 1972-07-29 | 1978-11-24 | ||
| SE428686B (sv) * | 1975-08-11 | 1983-07-18 | Du Pont | Forfarande for framstellning av antiinflammatoriskt aktiva imidazoler |
| DK16778A (da) * | 1977-02-09 | 1978-08-10 | Du Pont | Imidazolderivater deres anvendelser og fremstilling |
| US4159338A (en) * | 1977-02-09 | 1979-06-26 | E. I. Du Pont De Nemours And Company | Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones |
| LU77703A1 (de) * | 1977-07-07 | 1979-03-26 | Ciba Geigy Ag | Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen |
| DE2823197A1 (de) * | 1978-05-24 | 1979-11-29 | Schering Ag | Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| US4308277A (en) * | 1978-08-10 | 1981-12-29 | Ciba-Geigy Corporation | 2,4,5-Trisubstituted imidazolines and pharmaceutical compositions containing same |
| US4175127A (en) * | 1978-09-27 | 1979-11-20 | Smithkline Corporation | Pyridyl substituted 2,3-dihydroimidazo[2,1-b]thiazoles |
| DE2856909A1 (de) * | 1978-12-28 | 1980-07-17 | Schering Ag | Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
-
1979
- 1979-03-30 DE DE7979100962T patent/DE2963572D1/de not_active Expired
- 1979-03-30 EP EP79100962A patent/EP0004648B1/de not_active Expired
- 1979-03-30 CY CY1302A patent/CY1302A/xx unknown
- 1979-04-06 PL PL1979226123A patent/PL125882B1/pl unknown
- 1979-04-06 PL PL1979214745A patent/PL125972B1/pl unknown
- 1979-04-06 GR GR58824A patent/GR71193B/el unknown
- 1979-04-09 FI FI791158A patent/FI65066C/fi not_active IP Right Cessation
- 1979-04-09 DD DD79212098A patent/DD142712A5/de unknown
- 1979-04-10 KR KR7901118A patent/KR820002314B1/ko active
- 1979-04-10 NZ NZ190153A patent/NZ190153A/en unknown
- 1979-04-10 AU AU45994/79A patent/AU532402B2/en not_active Ceased
- 1979-04-10 NO NO791228A patent/NO148926C/no unknown
- 1979-04-10 ES ES479490A patent/ES8303355A1/es not_active Expired
- 1979-04-10 AT AT0266179A patent/AT376971B/de not_active IP Right Cessation
- 1979-04-10 IL IL57040A patent/IL57040A/xx unknown
- 1979-04-10 ZA ZA791702A patent/ZA791702B/xx unknown
- 1979-04-10 PT PT69460A patent/PT69460A/pt unknown
- 1979-04-10 SU SU2747651A patent/SU1259962A3/ru active
- 1979-04-10 HU HU79CI1925A patent/HU182018B/hu unknown
- 1979-04-10 CS CS792438A patent/CS220324B2/cs unknown
- 1979-04-10 DK DK148879A patent/DK148879A/da not_active IP Right Cessation
- 1979-04-11 JP JP4311779A patent/JPS54135769A/ja active Granted
-
1980
- 1980-05-23 SU SU802925099A patent/SU991945A3/ru active
-
1981
- 1981-11-16 US US06/321,840 patent/US4461770A/en not_active Expired - Fee Related
-
1982
- 1982-09-16 ES ES515766A patent/ES8403877A1/es not_active Expired
- 1982-10-04 KR KR8204468A patent/KR820002315B1/ko active
-
1983
- 1983-12-30 ES ES528579A patent/ES8504737A1/es not_active Expired
- 1983-12-30 ES ES528581A patent/ES528581A0/es active Granted
- 1983-12-30 ES ES528580A patent/ES528580A0/es active Granted
-
1984
- 1984-03-09 US US06/588,024 patent/US4584310A/en not_active Expired - Fee Related
- 1984-03-09 US US06/588,025 patent/US4608382A/en not_active Expired - Fee Related
-
1985
- 1985-11-07 HK HK872/85A patent/HK87285A/xx unknown
-
1986
- 1986-12-30 MY MY271/86A patent/MY8600271A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DD142712A5 (de) | Verfahren zur herstellung neuer mercaptoimidazolderivate | |
| DE69129428T2 (de) | Schwefelderivate von Imidazol, Verfahren zu ihrer Herstellung, Zwischenprodukte, ihre Verwendung als Arzneimittel und sie enthaltende pharmazeutische Zusammensetzungen | |
| DE69906554T2 (de) | P38 inhibitoren | |
| DE2655681A1 (de) | Substituierte imidazo eckige klammer auf 1,2-a eckige klammer zu pyridine | |
| DE2542329A1 (de) | Verfahren zur herstellung von neuen 2,3-dihydro-1-benzothiepin-4-carbonsaeureamiden | |
| DD145101A5 (de) | Verfahren zur herstellung von inda yl-derivaten | |
| DD145538A5 (de) | Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen | |
| EP0214479A2 (de) | Benzimidazol-2-yl-pyridiniumverbindungen | |
| DE3509333A1 (de) | Substituierte benzimidazolderivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer | |
| DE2363511A1 (de) | Pyrazol-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel | |
| EP0473963A1 (de) | Neue Pyrrolobenzimidazole, Imidazobenzoxazinone und Imidazochinolone, Verfahren zu ihrer Herstellung und ihre Verwendung sowie die Verbindungen enthaltende Zubereitungen | |
| AT374198B (de) | Verfahren zur herstellung neuer 2-substituierter mercaptoimidazolderivate, ihrer n-oxyde und ihrer salze | |
| DD145269A5 (de) | Verfahren zur herstellung neuer thiosubstituierter diazacycloalkene | |
| WO1992022536A1 (de) | Bicyclisch substituierte vinylimidazole, -triazole und -tetrazole | |
| EP0163842A1 (de) | Tricyclische Imidazolderivate | |
| AT375933B (de) | Verfahren zur herstellung neuer 2-substituierter mercaptoimidazolderivate und ihrer salze | |
| DE2805167A1 (de) | Entzuendungshemmende imidazole, verfahren zu ihrer herstellung und sie entheltende arzneimittel | |
| EP1100775A2 (de) | 2,5-substituierte benzolsulfonylharnstoffe und -thioharnstoffe, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmzeutische präparate | |
| DE3124673A1 (de) | Subsituierte 2-amino-pyridinderivate, verfahren zu ihrer herstellung, ihre verwendung in arzneimitteln, sowie deren herstellung | |
| EP0124630A1 (de) | Pyrimidin-Thioalkylpyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindung enthaltende Arzneimittel | |
| DE1950990A1 (de) | Verfahren zur Herstellung von neuen triazacyclischen Verbindungen | |
| DD201788A5 (de) | Verfahren zur herstellung neuer diaryl-imidazol-verbindungen | |
| DE2428294A1 (de) | Mercaptomethylpyridine und derivate derselben | |
| DD234005A5 (de) | Verfahren zur herstellung neuer 1,2,4-triazacycloalkadienderivate | |
| DE2357277A1 (de) | (1-alkyl-5-nitro-imidazolyl-2-alkyl)- pyridyl-verbindungen und verfahren zu ihrer herstellung |